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Journal Articles

Expanded Assessments of Germline Genetic Variants Identify Additional Risk Loci for Langerhans Cell Histiocytosis

Erin Peckham-Gregory, Priya Bhatia Shetty, Erik Stricker, Danielle Mitchell, Howard Lin, Brooks Scull, Erik Ehli, Christel Davis, Kenneth L. McClain, Philip J. Lupo, Carl E Allen, Michael E. Scheurer

Blood (2023) 142 (Supplement 1): 3193.

https://doi.org/10.1182/blood-2023-189670

Published: 2023

Journal Articles

Responses to Combination Chemotherapy with MAPK Pathway Inhibition in Relapsed and Refractory LCH

Vivekanudeep Karri, Nader Kim El-Mallawany, Howard Lin, Harshal A Abhyankar, Jennifer Elise Agrusa, Jessica Velazquez, Olive S. Eckstein, Nitya Gulati, Carl E Allen, Kenneth L. McClain

Blood (2023) 142 (Supplement 1): 6349.

https://doi.org/10.1182/blood-2023-190403

Published: 2023

Journal Articles

Retrospective Analysis of Clofarabine Salvage Therapy in Refractory Multifocal Langerhans Cell Histiocytosis (LCH)

Deevyashali Parekh, Howard Lin, Kenneth L. McClain, Nitya Gulati, Olive S. Eckstein, Nader Kim El-Mallawany, Jennifer Elise Agrusa, Carl E Allen

Blood (2023) 142 (Supplement 1): 4574.

https://doi.org/10.1182/blood-2023-184714

Published: 2023

Journal Articles

Identification of Germline, Ancestry-Specific Variants for Langerhans Cell Histiocytosis in Hispanic Patients

Priya Bhatia Shetty, Erin Peckham-Gregory, Erik Stricker, Howard Lin, Brooks Scull, Erik Ehli, Christel Davis, Kenneth L. McClain, Philip J. Lupo, Carl E Allen, Michael E. Scheurer

Blood (2023) 142 (Supplement 1): 4581.

https://doi.org/10.1182/blood-2023-191003

Published: 2023

Journal Articles

Myeloid Progenitors Define Extent of Disease in Mouse Models of Histiocytic Disorders: BRAF V600E Expression in Monocyte Lineage Recapitulates Erdheim-Chester Phenotype

C. Matthias Wilk, Brooks Scull, Ryan Fleischmann, Tsz-Kwong Man, Kenneth L. McClain, Miriam Merad, Florent Ginhoux, Carl E. Allen

Blood (2022) 140 (Supplement 1): 9597.

https://doi.org/10.1182/blood-2022-168116

Published: 2022

Journal Articles

Fine-Mapping of SMAD6 Sequence Data Identifies Additional Putative Risk Loci for Langerhans Cell Histiocytosis

Erin Peckham-Gregory, Priya B Shetty, Howard Lin, Brooks Scull, Erik Ehli, Kenneth L. McClain, Philip J. Lupo, Carl E. Allen, Michael E. Scheurer

Blood (2022) 140 (Supplement 1): 3953–3954.

https://doi.org/10.1182/blood-2022-170418

Published: 2022

Journal Articles

International expert consensus recommendations for the diagnosis and treatment of Langerhans cell histiocytosis in adults

Gaurav Goyal, Abdellatif Tazi, Ronald S. Go, Karen L. Rech, Jennifer L. Picarsic, Robert Vassallo, Jason R. Young, Christian W. Cox, Jan Van Laar, Michelle L. Hermiston, Xin-Xin Cao, Polyzois Makras, Gregory Kaltsas, Julien Haroche, Matthew Collin, Kenneth L. McClain, Eli L. Diamond, Michael Girschikofsky

Blood (2022) 139 (17): 2601–2621.

https://doi.org/10.1182/blood.2021014343

Published: 2022

Includes: Supplemental data

Journal Articles

BRAF V600E vs cell of origin: what governs LCH?

Kenneth L. McClain, Rikhia Chakraborty

Blood (2021) 138 (14): 1203–1204.

https://doi.org/10.1182/blood.2021012907

Published: 2021

Journal Articles

Overcoming T-cell exhaustion in LCH: PD-1 blockade and targeted MAPK inhibition are synergistic in a mouse model of LCH

Amel Sengal, Jessica Velazquez, Meryl Hahne, Thomas M. Burke, Harshal Abhyankar, Robert Reyes, Walter Olea, Brooks Scull, Olive S. Eckstein, Camille Bigenwald, Catherine M. Bollard, Wendong Yu, Miriam Merad, Kenneth L. McClain, Carl E. Allen, Rikhia Chakraborty

Blood (2021) 137 (13): 1777–1791.

https://doi.org/10.1182/blood.2020005867

Published: 2021

Includes: Supplemental data

Journal Articles

ALPS or not?

Kenneth L. McClain, Nitya Gulati

Blood (2020) 136 (17): 1895–1896.

https://doi.org/10.1182/blood.2020007418

Published: 2020

Journal Articles

Erdheim-Chester disease: consensus recommendations for evaluation, diagnosis, and treatment in the molecular era

Blood (2020) 135 (22): 1929–1945.

https://doi.org/10.1182/blood.2019003507

Published: 2020

Journal Articles

Checkmate for EBV-HLH

Nader Kim El-Mallawany, Kenneth L. McClain

Blood (2020) 135 (11): 782–784.

https://doi.org/10.1182/blood.2020005041

Published: 2020

Journal Articles

Blocking MAPK Activation and Immune Checkpoints Reverse Immune Dysfunction and Reduce Disease in a Mouse Model of LCH

Amel Sengal, BS, Meryl Hahne, Jessica Velasquez, Harshal Abhyankar, MS, Thomas Burke, BS, Walter Olea, Robert Reyes, Brooks Scull, MS, Camille Bigenwald, Catherine M. Bollard, MD, Wendong Yu, Miriam Merad, MD, Kenneth L. McClain, MD PhD, Carl E. Allen, MD PhD, Rikhia Chakraborty, PhD

Blood (2019) 134 (Supplement_1): 3602.

https://doi.org/10.1182/blood-2019-128253

Published: 2019

Journal Articles

Genomic Characterization of a Pediatric Cohort with Non-Malignant Lymphoproliferative Disorders

Blood (2019) 134 (Supplement_1): 83.

https://doi.org/10.1182/blood-2019-131884

Published: 2019

Journal Articles

Comprehensive Cell Specific Transcriptome Profiling of a Pediatric Hodgkin Lymphoma Cohort

Jennifer Agrusa, MD, Elmoataz A Abdel Fattah, MBBCh, Howard Lin, BS, Rikhia Chakraborty, PhD, Brooks Scull, MS, Harshal Abhyankar, MS, Nmazuo Wudo Ozuah, MBBS, Olive S. Eckstein, MD, Terzah M Horton, MD PhD, Kala Kamdar, MD, Kenneth L. McClain, MD PhD, Chris Tsz-Kwong Man, PhD, Carl E. Allen, MD PhD

Blood (2019) 134 (Supplement_1): 2773.

https://doi.org/10.1182/blood-2019-125982

Published: 2019

Journal Articles

Inherited Genetic Risk Factors and Langerhans Cell Histiocytosis Relapse Events

Erin Peckham-Gregory, PhD, Michael Scheurer, MPH, PhD, Rikhia Chakraborty, PhD, Harshal Abhyankar, MS, Kenneth L. McClain, MD PhD, Carl E. Allen, MD PhD, Philip J Lupo, PhD

Blood (2018) 132 (Supplement 1): 4278.

https://doi.org/10.1182/blood-2018-99-118743

Published: 2018

Journal Articles

Evaluating Anti-TNF-Alpha Therapy in Patients with Relapsed and Refractory Langerhans Cell Histiocytosis

Thomas Burke, BS, Alejandra Legarreta, MD, Howard Lin, Brooks Scull, Olive S. Eckstein, MD, Kenneth L. McClain, MD PhD, Carl E. Allen, MD PhD

Blood (2018) 132 (Supplement 1): 4941.

https://doi.org/10.1182/blood-2018-99-114295

Published: 2018

Journal Articles

Clinical Outcomes and Molecular Responses in Children with Langerhans Cell Histiocytosis Treated with MAPK Pathway Inhibitors

Olive S. Eckstein, MD, Daniel Zinn, MD, Carolyn Fein Levy, MD, Michael M. Henry, MD, Patrick Campbell, MD, Michael B. Jordan, MD, Ashish R Kumar, MD PhD, Carlos Rodriguez-Galindo, MD PhD, Nobuko Hijiya, MD, Oussama Abla, MD, Kenneth L. McClain, MD PhD, Carl E. Allen, MD PhD

Blood (2018) 132 (Supplement 1): 3684.

https://doi.org/10.1182/blood-2018-99-120393

Published: 2018

Journal Articles

HLH: watch and wait, or act and cure ?

Kenneth L. McClain, Caridad A. Martinez

Blood (2018) 132 (19): 2005–2006.

https://doi.org/10.1182/blood-2018-09-873646

Published: 2018

Journal Articles

Genetic and mechanistic diversity in pediatric hemophagocytic lymphohistiocytosis

Blood (2018) 132 (1): 89–100.

https://doi.org/10.1182/blood-2017-11-814244

Published: 2018

Includes: Supplemental data

NARROW

Expanded Assessments of Germline Genetic Variants Identify Additional Risk Loci for Langerhans Cell Histiocytosis

Responses to Combination Chemotherapy with MAPK Pathway Inhibition in Relapsed and Refractory LCH

Retrospective Analysis of Clofarabine Salvage Therapy in Refractory Multifocal Langerhans Cell Histiocytosis (LCH)

Identification of Germline, Ancestry-Specific Variants for Langerhans Cell Histiocytosis in Hispanic Patients

Myeloid Progenitors Define Extent of Disease in Mouse Models of Histiocytic Disorders: BRAF V600E Expression in Monocyte Lineage Recapitulates Erdheim-Chester Phenotype

Fine-Mapping of SMAD6 Sequence Data Identifies Additional Putative Risk Loci for Langerhans Cell Histiocytosis

International expert consensus recommendations for the diagnosis and treatment of Langerhans cell histiocytosis in adults

BRAF V600E vs cell of origin: what governs LCH?

Overcoming T-cell exhaustion in LCH: PD-1 blockade and targeted MAPK inhibition are synergistic in a mouse model of LCH

ALPS or not?

Erdheim-Chester disease: consensus recommendations for evaluation, diagnosis, and treatment in the molecular era

Checkmate for EBV-HLH

Blocking MAPK Activation and Immune Checkpoints Reverse Immune Dysfunction and Reduce Disease in a Mouse Model of LCH

Genomic Characterization of a Pediatric Cohort with Non-Malignant Lymphoproliferative Disorders

Comprehensive Cell Specific Transcriptome Profiling of a Pediatric Hodgkin Lymphoma Cohort

Inherited Genetic Risk Factors and Langerhans Cell Histiocytosis Relapse Events

Evaluating Anti-TNF-Alpha Therapy in Patients with Relapsed and Refractory Langerhans Cell Histiocytosis

Clinical Outcomes and Molecular Responses in Children with Langerhans Cell Histiocytosis Treated with MAPK Pathway Inhibitors

HLH: watch and wait, or act and cure ?

Genetic and mechanistic diversity in pediatric hemophagocytic lymphohistiocytosis

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American Society of Hematology

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ASH Publications

American Society of Hematology

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