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Journal Articles

Identification of Germline, Ancestry-Specific Variants for Langerhans Cell Histiocytosis in Hispanic Patients

Priya Bhatia Shetty, Erin Peckham-Gregory, Erik Stricker, Howard Lin, Brooks Scull, Erik Ehli, Christel Davis, Kenneth L. McClain, Philip J. Lupo, Carl E Allen, Michael E. Scheurer
Journal: Blood
Blood (2023) 142 (Supplement 1): 4581.
https://doi.org/10.1182/blood-2023-191003
Published: 2023
Journal Articles

Expanded Assessments of Germline Genetic Variants Identify Additional Risk Loci for Langerhans Cell Histiocytosis

Erin Peckham-Gregory, Priya Bhatia Shetty, Erik Stricker, Danielle Mitchell, Howard Lin, Brooks Scull, Erik Ehli, Christel Davis, Kenneth L. McClain, Philip J. Lupo, Carl E Allen, Michael E. Scheurer
Journal: Blood
Blood (2023) 142 (Supplement 1): 3193.
https://doi.org/10.1182/blood-2023-189670
Published: 2023
Journal Articles

Myeloid Progenitors Define Extent of Disease in Mouse Models of Histiocytic Disorders: BRAF V600E Expression in Monocyte Lineage Recapitulates Erdheim-Chester Phenotype

C. Matthias Wilk, Brooks Scull, Ryan Fleischmann, Tsz-Kwong Man, Kenneth L. McClain, Miriam Merad, Florent Ginhoux, Carl E. Allen
Journal: Blood
Blood (2022) 140 (Supplement 1): 9597.
https://doi.org/10.1182/blood-2022-168116
Published: 2022
Journal Articles

Fine-Mapping of SMAD6 Sequence Data Identifies Additional Putative Risk Loci for Langerhans Cell Histiocytosis

Erin Peckham-Gregory, Priya B Shetty, Howard Lin, Brooks Scull, Erik Ehli, Kenneth L. McClain, Philip J. Lupo, Carl E. Allen, Michael E. Scheurer
Journal: Blood
Blood (2022) 140 (Supplement 1): 3953–3954.
https://doi.org/10.1182/blood-2022-170418
Published: 2022
Journal Articles

Peri-Transplant Alemtuzumab Levels Predict Risk of Secondary Graft Failure and Inversely Impact CXCL9 Levels after RIC HCT (A Correlative Biology Study to BMT-CTN 1204 RICHI)

Ashley V Geerlinks, Brooks Scull, Christa Krupski, Ryan Fleischmann, Michael A. Pulsipher, Mary Eapen, Jim A. Connelly, Catherine M. Bollard, Sung-Yun Pai, Christine N. Duncan, Leslie S Kean, K. Scott Baker, Lauri S Burroughs, Jeffrey R. Andolina, Michael B Jordan, Tsz-Kwong Man, Carl E. Allen, Rebecca A. Marsh
Journal: Blood
Blood (2021) 138 (Supplement 1): 748.
https://doi.org/10.1182/blood-2021-145629
Published: 2021
Journal Articles

Overcoming T-cell exhaustion in LCH: PD-1 blockade and targeted MAPK inhibition are synergistic in a mouse model of LCH

Amel Sengal, Jessica Velazquez, Meryl Hahne, Thomas M. Burke, Harshal Abhyankar, Robert Reyes, Walter Olea, Brooks Scull, Olive S. Eckstein, Camille Bigenwald, Catherine M. Bollard, Wendong Yu, Miriam Merad, Kenneth L. McClain, Carl E. Allen, Rikhia Chakraborty
Journal: Blood
Blood (2021) 137 (13): 1777–1791.
https://doi.org/10.1182/blood.2020005867
Published: 2021
Includes: Supplemental data
Journal Articles

Comprehensive Cell Specific Transcriptome Profiling of a Pediatric Hodgkin Lymphoma Cohort

Jennifer Agrusa, MD, Elmoataz A Abdel Fattah, MBBCh, Howard Lin, BS, Rikhia Chakraborty, PhD, Brooks Scull, MS, Harshal Abhyankar, MS, Nmazuo Wudo Ozuah, MBBS, Olive S. Eckstein, MD, Terzah M Horton, MD PhD, Kala Kamdar, MD, Kenneth L. McClain, MD PhD, Chris Tsz-Kwong Man, PhD, Carl E. Allen, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2773.
https://doi.org/10.1182/blood-2019-125982
Published: 2019
Journal Articles

Blocking MAPK Activation and Immune Checkpoints Reverse Immune Dysfunction and Reduce Disease in a Mouse Model of LCH

Amel Sengal, BS, Meryl Hahne, Jessica Velasquez, Harshal Abhyankar, MS, Thomas Burke, BS, Walter Olea, Robert Reyes, Brooks Scull, MS, Camille Bigenwald, Catherine M. Bollard, MD, Wendong Yu, Miriam Merad, MD, Kenneth L. McClain, MD PhD, Carl E. Allen, MD PhD, Rikhia Chakraborty, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3602.
https://doi.org/10.1182/blood-2019-128253
Published: 2019
Journal Articles

Evaluating Anti-TNF-Alpha Therapy in Patients with Relapsed and Refractory Langerhans Cell Histiocytosis

Thomas Burke, BS, Alejandra Legarreta, MD, Howard Lin, Brooks Scull, Olive S. Eckstein, MD, Kenneth L. McClain, MD PhD, Carl E. Allen, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4941.
https://doi.org/10.1182/blood-2018-99-114295
Published: 2018
Journal Articles

Plasma Inflammatory Protein Profiles Distinguish Hemophagocytic Lymphohistiocytosis from Sepsis and SIRS

Harshal Abhyankar, MS, Carl E. Allen, MD PhD, Howard Lin, Baruch Goldberg, Brooks Scull, Kenneth L. McClain, MD PhD, Jordana Goldman, Trung Nguyen, Michael B. Jordan, MD, Tsz-kwong Man, Olive S. Eckstein, MD, Joseph Lubega, Dalia Bashir, Rikhia Chakraborty, PhD BSc, MSc, Hector Wong, Eyal Muscal, Daniel Zinn, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1011.
https://doi.org/10.1182/blood.V130.Suppl_1.1011.1011
Published: 2017
Journal Articles

Immune Checkpoint Inhibitors Restore Function of Lesion Infiltrating T Lymphocytes in Langerhans Cell Histiocytosis

Rikhia Chakraborty, PhD BSc, MSc, Carl E. Allen, MD PhD, Amel Sengal, BS, Amos S. Gaikwad, PhD, Harshal Abhyankar, MS, Brooks Scull, Olive S. Eckstein, MD, Miriam Merad, MD, Kenneth L. McClain, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2280.
https://doi.org/10.1182/blood.V130.Suppl_1.2280.2280
Published: 2017
Journal Articles

BRAF-V600E in Peripheral Mononuclear Cells and Microglia-like Brain Cells Suggest Hematopoietic Origin of Langerhans Cell Histiocytosis-Associated Neurodegeneration

Daniel Zinn, MD, Jennifer Picarsic, Rikhia Chakraborty, PhD BSc, MSc, Howard Lin, Harshal Abhyankar, MS, Brooks Scull, Albert Shih, Karen Phaik Har Lim, Olive S. Eckstein, MD, Tricia L. Peters, MD, Walter Olea, Thomas Burke, Nabil Ahmed, MD, John Hicks, Brandon Tran, Jeremy Jones, Robert Dauser, Michael R. Jeng, MD, Robert A Baiocchi, MD PhD, Deborah E. Schiff, MD, Stanton Goldman, MD, Kenneth Matthew Heym, MD, Harry Wilson, Benjamin Carcamo, Ashish Kumar, MBBS, Carlos Rodriguez-Galindo, MD, Nicholas Whipple, Patrick Campbell, MD PhD, Geoffrey Murdoch, Simon Heales, Marian Malone, Randy Woltjer, Joseph Quinn, Paul Orchard, MD, Michael Kruer, Ronald Jaffe, Markus G Manz, MD, Sergio Lira, Donald Will Parsons, MD PhD, Miriam Merad, MD, Tsz-kwong Man, Kenneth L. McClain, MD PhD, Carl E. Allen, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2930.
https://doi.org/10.1182/blood.V130.Suppl_1.2930.2930
Published: 2017
Journal Articles

Clonal, Exhausted and Activated Infiltrating T Lymphocytes in Langerhans Cell Histiocytosis Lesions

Rikhia Chakraborty, PhD, Amel G Sengal, MS, Meryl Hahne, BS, Amos S. Gaikwad, PhD, Brooks Scull, MS, Harshal Abhyankar, MS, Miriam Merad, MD PhD, Kenneth McClain, MD PhD, Carl E. Allen, MD PhD
Journal: Blood
Blood (2016) 128 (22): 3708.
https://doi.org/10.1182/blood.V128.22.3708.3708
Published: 2016
Journal Articles

Alternative genetic mechanisms of BRAF activation in Langerhans cell histiocytosis

Clinical Trials & Observations Brief Report
Rikhia Chakraborty, Thomas M. Burke, Oliver A. Hampton, Daniel J. Zinn, Karen Phaik Har Lim, Harshal Abhyankar, Brooks Scull, Vijetha Kumar, Nipun Kakkar, David A. Wheeler, Angshumoy Roy, Poulikos I. Poulikakos, Miriam Merad, Kenneth L. McClain, D. Williams Parsons, Carl E. Allen
Journal: Blood
Blood (2016) 128 (21): 2533–2537.
https://doi.org/10.1182/blood-2016-08-733790
Published: 2016
Includes: Supplemental data
Journal Articles

A Genome-Wide Assessment of Inherited Genetic Variants and the Risk of Langerhans Cell Histiocytosis

Erin Peckham, PhD, Philip J Lupo, PhD MPH, Michael E Scheurer, PhD MPH, Rikhia Chakraborty, PhD BSc, MSc, John Belmont, MDPhD, Spiridon Tsavachidis, MS, Albert Shih, BS, Harshal Abhyankar, MS, Karen Phaik Har Lim, MS, Brooks Scull, MS, Kenneth L. McClain, MD PhD, Carl Allen, MD PhD
Journal: Blood
Blood (2015) 126 (23): 4059.
https://doi.org/10.1182/blood.V126.23.4059.4059
Published: 2015
Journal Articles

Inflammatory Plasma Proteins Predict Disease Severity and Response to Therapy in Patients with LCH

Daniel Zinn, MD, Howard Lin, Albert Shih, BS, Brooks Scull, MS, Miguel Dario Cantu, Harshal Abhyankar, MS, Rikhia Chakraborty, PhD BSc, MSc, Karen Phaik Har Lim, Tricia L. Peters, MD, Sergio Lira, MD PhD, Chris Tsz-Kwong, PhD, Kenneth McClain, MD PhD, Miriam Merad, MD PhD, Carl Allen, MD PhD
Journal: Blood
Blood (2015) 126 (23): 4072.
https://doi.org/10.1182/blood.V126.23.4072.4072
Published: 2015