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Vanessa Gonzalez
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Journal Articles

IL-10 Levels Differentially Regulate IFNg Signaling of CART19 and CART22

Caroline Diorio, Regina M. Myers, Anastasia Frank-Kamenetski, Rawan Shraim, Amanda M. Dinofia, Zachary Martinez, Ohaila Mustafa, Joseph A Fraietta, Vanessa Gonzalez, Vivian Yi, Lahari Uppuluri, Haley Newman, Edward Behrens, Carl June, Scott Canna, Stephan Grupp, David T. Teachey
Journal: Blood
Blood (2023) 142 (Supplement 1): 3431.
https://doi.org/10.1182/blood-2023-182377
Published: 2023
Journal Articles

CD22-Targeted CAR-Modified T-Cells Safely Induce Remissions in Children and Young Adults with Relapsed, CD19-Negative B-ALL after Treatment with CD19-Targeted CAR T-Cells

Regina M. Myers, Amanda M. DiNofia, Yimei Li, Caroline Diorio, Richard Aplenc, Diane Baniewicz, Jennifer L Brogdon, Colleen Callahan, Boris Engels, Joseph A. Fraietta, Vanessa Gonzalez, Emma Iannone, Allison Barz Leahy, Hongyan Liu, Susan E. McClory, Susan R. Rheingold, Laura Shinehouse, Gerald Wertheim, Lisa Wray, Noelle V. Frey, Shannon L. Maude, Stephan A. Grupp
Journal: Blood
Blood (2022) 140 (Supplement 1): 2376–2377.
https://doi.org/10.1182/blood-2022-168139
Published: 2022
Journal Articles

Checkpoint Inhibitors Augment CD19-Directed Chimeric Antigen Receptor (CAR) T Cell Therapy in Relapsed B-Cell Acute Lymphoblastic Leukemia

Amanda M. Li, MD, George E Hucks, Amanda M. Dinofia, MD, Alix E. Seif, MD, David T Teachey, MD, Diane Baniewicz, Colleen Callahan, Christina Fasano, Beth McBride, Vanessa Gonzalez, Farzana Nazimuddin, MS, David L. Porter, MD, Simon F Lacey, PhD BS, Carl H June, MD, Stephan A. Grupp, MD PhD, Shannon L. Maude, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 556.
https://doi.org/10.1182/blood-2018-99-112572
Published: 2018
Journal Articles

PD-1 Inhibitor Combinations As Salvage Therapy for Relapsed/Refractory Multiple Myeloma (MM) Patients Progressing after Bcma-Directed CAR T Cells

Luca Bernabei, Alfred L. Garfall, MD, J. Joseph Melenhorst, PhD, Simon F Lacey, PhD BS, Edward A. Stadtmauer, MD FACP, Dan T. Vogl, MD, Vanessa Gonzalez, Gabriela Plesa, MD, Regina M Young, PhD, Adam Waxman, MD, Bruce L Levine, PhD, Carl H June, MD, Michael C. Milone, MD PhD, Adam D. Cohen, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1973.
https://doi.org/10.1182/blood-2018-99-119514
Published: 2018
Journal Articles

Predictors of T Cell Expansion and Clinical Responses Following B-Cell Maturation Antigen-Specific Chimeric Antigen Receptor T Cell Therapy (CART-BCMA) for Relapsed/Refractory Multiple Myeloma (MM)

Adam D. Cohen, MD, J. Joseph Melenhorst, PhD, Alfred L. Garfall, MD, Simon F Lacey, PhD BS, Megan Davis, PhD, Dan T. Vogl, MD, Lifeng Tian, PhD, Vanessa Gonzalez, Iulian Pruteanu, PhD, Anne Marie Nelson, Gabriela Plesa, MD, Adam Waxman, MD, Regina M Young, PhD, Bruce L Levine, PhD, Carl H June, MD, Edward A. Stadtmauer, MD FACP, Michael C. Milone, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1974.
https://doi.org/10.1182/blood-2018-99-119665
Published: 2018
Journal Articles

Safety and Efficacy of B-Cell Maturation Antigen (BCMA)-Specific Chimeric Antigen Receptor T Cells (CART-BCMA) with Cyclophosphamide Conditioning for Refractory Multiple Myeloma (MM)

Adam D. Cohen, MD, Alfred L. Garfall, MD, Edward A. Stadtmauer, MD FACP, Simon F Lacey, PhD BS, Eric Lancaster, Dan T. Vogl, MD, Brendan M Weiss, MD, David E Ambrose, BS, Anne Marie Nelson, Fang Chen, PhD, Gabriela Plesa, MD, Irina Kulikovskaya, Vanessa Gonzalez, Minnal Gupta, Regina M Young, PhD, Karen Dengel, BSN, RN, Laura O'keefe, Samantha Le, Celeste Richardson, PhD, Randi E. Isaacs, MD, J. Joseph Melenhorst, PhD, Bruce L Levine, PhD, Carl H June, MD, Michael C. Milone, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 505.
https://doi.org/10.1182/blood.V130.Suppl_1.505.505
Published: 2017
Journal Articles

PD-1 blockade modulates chimeric antigen receptor (CAR)–modified T cells: refueling the CAR

Clinical Trials & Observations
Elise A. Chong, J. Joseph Melenhorst, Simon F. Lacey, David E. Ambrose, Vanessa Gonzalez, Bruce L. Levine, Carl H. June, Stephen J. Schuster
Journal: Blood
Blood (2017) 129 (8): 1039–1041.
https://doi.org/10.1182/blood-2016-09-738245
Published: 2017
Journal Articles

Biomarkers Accurately Predict Cytokine Release Syndrome (CRS) after Chimeric Antigen Receptor (CAR) T Cell Therapy for Acute Lymphoblastic Leukemia (ALL)

David T Teachey, MD, Simon F. Lacey, PhD BSc, Pamela A Shaw, PhD, J Joseph Melenhorst, PhD, Noelle V. Frey, MD, Shannon L Maude, MD PhD, David M. Barrett, MD PhD, Richard Aplenc, MD PhD, Fang Chen, PhD, Julie Fitzgerald, MD PhD, Vanessa Gonzalez, M.B.A, Edward Pequignot, PhD, Susan R. Rheingold, MD, Scott Weiss, MD, Jason C. White, DO, Carl H. June, MD, David L. Porter, MD, Stephan A. Grupp, MD PhD
Journal: Blood
Blood (2015) 126 (23): 1334.
https://doi.org/10.1182/blood.V126.23.1334.1334
Published: 2015
Journal Articles

Cytokine Release Syndrome (CRS) after Chimeric Antigen Receptor (CAR) T Cell Therapy for Relapsed/Refractory (R/R) CLL

David L. Porter, MD, Simon F. Lacey, PhD BSc, Wei-Ting Hwang, PhD, Pamela Shaw, PhD, Noelle V. Frey, MDMS, Anne Chew, PhD, Fang Chen, PhD, Michael Kalos, PhD, Vanessa Gonzalez, PhD, Katherine T. Marcucci, PhD, Shannon L Maude, MD PhD, Jan J Melenhorst, PhD, Manuel Litchman, MD, David T. Teachey, MD, Angela Shen, MD, Alfonso Quintas-Cardamas, MD, Patricia A. Wood, MD PhD, Bruce L. Levine, PhD, Carl H. June, MD, Stephan A. Grupp, MD PhD
Journal: Blood
Blood (2014) 124 (21): 1983.
https://doi.org/10.1182/blood.V124.21.1983.1983
Published: 2014