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David de Leeuw
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Journal Articles

ALIDHE: An ongoing open-label phase 3b study investigating ivosidenib with azacitidine in clinical practice in adult patients with newly diagnosed mutant isocitrate dehydrogenase 1 (mIDH1) Acute Myeloid Leukemia (AML) ineligible for intensive induction chemotherapy (IC)

Free
Paresh Vyas, Christian Recher, Hartmut Döhner, Adriano Venditti, Sam Salek, Samantha Nier, Blanca Boluda, Gaspar Aspas Requena, Raja Prince-Eladnani, Erika Borlenghi, Antonio Curti, Koen Theunissen, Alba Puyuelo, Ioana Codruta Rus, David de Leeuw, Emanuele Ammatuna, Lalit Saini, Johan Maertens, Andre Schuh, Dilza Camanho, Adam Sullivan, Anne-Marie De La Bigne, Mathilde Romagnoli, Bénédicte Cognet, Courtney DiNardo, Susana Vives
Journal: Blood
Blood (2025) 146 (Supplement 1): 3443.
https://doi.org/10.1182/blood-2025-3443
Published: 2025
Journal Articles

Phase 1/2 study of MP0533, a tetra-specific T cell engager (CD33 x CD123 x CD70 x CD3), in patients with relapsed/refractory AML or MDS/AML: Initial results from optimized treatment regimen including densified MP0533 dosing and adapted premedication

Free
Pierre Bories, Mojca Jongen-Lavrencic, Laimonas Griškevičius, Thomas Pabst, David de Leeuw, Gerwin A. Huls, Nicolas Boissel, Arnaud Pigneux, Steffen Boettcher, Mariola Dymkowska, Christiane Andrieu, Elena Fernandez, Paul Baverel, Vaia Stavropoulou, Michael Sanderson, Vladimir Kirkin, Philippe Legenne, Marion Subklewe
Journal: Blood
Blood (2025) 146 (Supplement 1): 3419.
https://doi.org/10.1182/blood-2025-3419
Published: 2025
Journal Articles

Establishing contemporary benchmarks for Acute Myeloid Leukemia outcomes and measurable residual disease: Real-world data utilization from the ELN-david MRD international working group

Free
Gail Roboz, Tom Reuvekamp, Jacqueline Cloos, Malte Von Bonin, Francesco Buccisano, Lukas Haaksma, Maura Ikoma-Colturato, Joana Brioso Infante, Dennis Kim, Chrysavgi Lalayanni, David de Leeuw, Josephine Anne Lucero, Francesco Mannelli, Luca Maurillo, Federico Moretti, Josep F Nomdedeu Guinot, Apostolia Papalexandri, Guillermo Ramil López, Maximilian Röhnert, Christoph Röllig, Anderson João Simione, Daniela Späth, Felicitas R Thol, Anne Tierens, Adriano Venditti, Francois Vergez, Michael Heuser, Konstanze Döhner
Journal: Blood
Blood (2025) 146 (Supplement 1): 5183.
https://doi.org/10.1182/blood-2025-5183
Published: 2025
Journal Articles

Umbilical cord blood CD34+ hematopoietic stem cell-derived natural killer cells in Acute Myeloid Leukemia – a phase I clinical study

Free
Michael Heuser, Anna-Maria Georgoudaki, Adrian Schwarzer, Arnold Kloos, Letizia Venturini, Walter Fiedler, Felicitas R Thol, Andreas Block, David de Leeuw, Arjan van de Loosdrecht, Jan Moritz Middeke, Astrid Tschan-Plessl, Jakob Passweg, Eva-Maria Wagner Drouet, Amanda van Vliet, Didem Özkazanc, Monica Raimo, Isabell Arnhardt, Michael Stadler, Arnold Ganser, Virginie Bonnamain, Jan Spanholtz, Adil Duru
Journal: Blood
Blood (2025) 146 (Supplement 1): 1640.
https://doi.org/10.1182/blood-2025-1640
Published: 2025