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Esperanza Such
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Journal Articles

Influence of TP53 gene mutations and their allelic status in myelodysplastic syndromes with isolated 5q deletion

CME Clinical Trials & Observations
Maria Julia Montoro, Laura Palomo, Claudia Haferlach, Pamela Acha, Onyee Chan, Víctor Navarro, Yasuo Kubota, Felicitas Isabel Schulz, Manja Meggendorfer, Robert Briski, Najla Al Ali, Blanca Xicoy, Félix López-Cadenas, Francesc Bosch, Teresa González, Lea Naomi Eder, Andrés Jerez, Yu-Hung Wang, Alessia Campagna, Valeria Santini, Teresa Bernal del Castillo, Esperanza Such, Hwei-Fang Tien, Nicolás Diaz Varela, Uwe Platzbecker, Detlef Haase, María Díez-Campelo, Matteo Della Porta, Guillermo Garcia-Manero, Daniel H. Wiseman, Ulrich Germing, Jaroslaw P. Maciejewski, Rami S. Komrokji, Francesc Sole, Torsten Haferlach, David Valcárcel
Journal: Blood
Blood (2024) 144 (16): 1722–1731.
https://doi.org/10.1182/blood.2024023840
Published: 2024
Includes: Supplemental data
Journal Articles

Enhancing Cytogenetic Diagnostics: Incorporating Optical Genome Mapping in the Laboratory Routine

Álvaro Díaz-González, Cristian García-Ruiz, Gayane Avetisyan, Gloria Llorens, José Vicente Gil, Elvira Mora, Santiago Furió, Empar Mayordomo, Carolina López-Benet, Marina Suárez-Terrón, Mireya Morote-Faubel, Marta Santiago, Samuel Romero, Marta Llop, Eva Barragán, Lourdes Cordón, Alessandro Liquori, Dolores Linares, Irene Luna, Ana Vicente, Rafael Andreu, Amparo Sempere, Leonor Senent, José Cervera, Guillermo Sanz, Javier De La Rubia, Esperanza Such
Journal: Blood
Blood (2023) 142 (Supplement 1): 5024.
https://doi.org/10.1182/blood-2023-180691
Published: 2023
Journal Articles

Role of Allogeneic Stem Cell Transplantation in Preventing Relapse in Adult BCR::ABL1-like Acute Lymphoblastic Leukemia

Jordi Ribera, Mireia Morgades, Isabel Granada, Teresa González, Ricardo Sánchez, Rosa Ayala, Esperanza Such, Gayane Avetisyan, Susana Barrera, Beatriz Soriano, Anna Torrent, Cristina Gil, Carmen Botella, Clara Maluquer Artigal, Pere Barba, Pau Montesinos, José González-Campos, Pilar Martínez-Sánchez, Rosa Coll, Jordi Esteve, Maria Rocio Benito Sanchez, Thaysa Lopes, Celia González Gil, Eulàlia Genescà, Joaquin Martínez-López, Jesús María Hernández-Rivas, Alberto Orfao, Josep-Maria Ribera
Journal: Blood
Blood (2023) 142 (Supplement 1): 1461.
https://doi.org/10.1182/blood-2023-186265
Published: 2023
Journal Articles

Mutually-Exclusive Pathways between IKZF1 plus and RAS Mutations and TP53 double-Hit Alterations Lead Relapse in B-Other, Ph-like and Hyperdiploidy Genetic Groups in Adult B-Cell Acute Lymphoblastic Leukemia

Josgrey Del Valle Del Valle Navas Acosta, Teresa González, Inmaculada Serramito-Gómez, Angela Villaverde Ramiro, Cristina Miguel-García, Sandra Santos-Mínguez, Jordi Ribera, Isabel Granada, Mireia Morgades, Ricardo Sanchez, Esperanza Such, Susana Barrera, Juana Ciudad, Alberto Orfao, Julio Davila Valls, Natalia De Las Heras, José Fuster, Alfonso Garcia de Coca, Jorge Labrador, Jose Antonio Queizan Hernandez, María Carmen Mendoza, Susana Riesco, Sandra Martín, Josep-Maria Ribera, Maria Rocio Benito Sanchez, Jesús María Hernández-Rivas
Journal: Blood
Blood (2023) 142 (Supplement 1): 1616.
https://doi.org/10.1182/blood-2023-182163
Published: 2023
Journal Articles

Cis-Acting Splicing-Associated Variants Can Redefine the Molecular Signature of Genes Commonly Mutated in Acute Myeloid Leukemia

Mireya Morote-Faubel, Maria Guaita-Céspedes, Beatriz Fernández-Blanco, Cristina Martínez-Valiente, Cristian García-Ruiz, Marta Santiago, Alvaro Diaz-Gonzalez, Alejandra Sanjuan-Pla, Mariam Ibáñez, Eva Barragan, Esperanza Such, Mireya Morote Faubel, Pau Montesinos, Javier De La Rubia, Alessandro Liquori, Jose Cervera
Journal: Blood
Blood (2023) 142 (Supplement 1): 2936.
https://doi.org/10.1182/blood-2023-177571
Published: 2023
Journal Articles

TP53 G ene a llelic State in Myelodysplastic Syndromes (MDS) with Isolated 5q Deletion

Julia Montoro, Laura Palomo, Claudia Haferlach, Pamela Acha, Onyee Chan, Victor Navarro Garces, Yasuo Kubota, Felicitas Schulz, Manja Meggendorfer, Robert Briski, Najla H Al Ali, Blanca Xicoy, Felix Lopez, Pablo Vidal, Francesc Bosch, Teresa González, Lea Naomi Eder, Andres Jerez, Hwei-Fang Tien, Valeria Santini, Teresa Bernal Del Castillo, Esperanza Such, Yu-Hung Wang, Anne Sophie Kubasch, Uwe Platzbecker, Detlef Haase, Maria Diez-Campelo, Matteo Giovanni Della Porta, Guillermo Garcia-Manero, Daniel H Wiseman, Ulrich Germing, Jaroslaw P. Maciejewski, Rami S. Komrokji, Francesc Sole, Torsten Haferlach, David Valcarcel
Journal: Blood
Blood (2023) 142 (Supplement 1): 1001.
https://doi.org/10.1182/blood-2023-179171
Published: 2023
Journal Articles

Clinical and Molecular Characterization of Patients with Therapy Related Myeloid Neoplasms (TRMN)

Oriol Calvete, Julia Mestre, Guillermo Montalban-Bravo, Koji Sasaki, Courtney D. DiNardo, Ana Manzanares, Pamela Acha, Blanca Xicoy, Lurdes Zamora, Isabel Granada, Alvaro Diaz-Gonzalez, Esperanza Such, Laura Palomo, Maria Julia Montoro, Sara García, Leonor Arenillas, David Valcarcel Ferreiras, Andres Jerez, Maria Diez-Campelo, Felipe Prosper, Hui Yang, Carlos E. Bueso-Ramos, Guillermo Garcia-Manero, Francesc Sole, Rashmi Kanagal-Shamanna
Journal: Blood
Blood (2023) 142 (Supplement 1): 3224.
https://doi.org/10.1182/blood-2023-188701
Published: 2023
Journal Articles

ERCC6L2 in Early-Onset Adult Myelodysplastic Syndrome without Pre-Existing Disorder

Salvador Carrillo-Tornel, Tzu Hua Chen-Liang, Ana Yeguas Bermejo, Helena Pomares, Alessandro Liquori, Teresa González, Teresa Bernal del Castillo, Marta Santiago, Félix López Cadenas, Bernardo López Andrade, Raul Teruel Montoya, Esperanza Such, Francisca Maria Hernandez, Blanca Xicoy, Montserrat Arnan Sangerman, Francesc Solé, Jose Cervera, Maria Diez-Campelo, Andres Jerez
Journal: Blood
Blood (2022) 140 (Supplement 1): 4074–4075.
https://doi.org/10.1182/blood-2022-168759
Published: 2022
Journal Articles

Pilot Inter-Laboratory Comparison Study of Optical Genome Mapping Analysis for Cytogenomic Characterization of Hematological Malignancies: A Spanish Multicentric Study

Anna Puiggros, Mar Mallo, Marta Salido, Ana Gómez-García, Adela Cisneros, Rocío García-Serra, Celia González-Gil, Gayane Avetisyan, María Rodríguez-Rivera, Alvaro Diaz-Gonzalez, Isabel Granada, Esperanza Such, Eulàlia Genescà, Rosa Collado, Manuel Ramírez-Orellana, Francesc Solé, Blanca Espinet
Journal: Blood
Blood (2022) 140 (Supplement 1): 4981–4983.
https://doi.org/10.1182/blood-2022-166293
Published: 2022
Journal Articles

TP53 Allelic State in Myelodysplastic Syndromes with 5q Deletion

Maria Julia Montoro Gómez, Laura Palomo, Pablo Vidal, Francisco Fuster-Tormo, Esperanza Such, Margarita Ortega, Teresa González, Felix Lopez-Cadenas, Sara Garcia-Avila, Nieves Garcia-Gisbert, Elvira Mora Casterá, Eugenia Rivero, Francesc Bosch, Andrés Jerez, Maria Diez-Campelo, Francesc Solé, David Valcárcel
Journal: Blood
Blood (2022) 140 (Supplement 1): 6949–6951.
https://doi.org/10.1182/blood-2022-165257
Published: 2022
Journal Articles

IKZF1 Deletions Are Markers of Treatment Resistance in Adult Ph-Negative B-Cell Acute Lymphoblastic Leukemia Patients Treated within the Ongoing Risk-Adapted Pethema LAL19 Trial

Jordi Ribera, Isabel Granada, Teresa González, Mireia Morgades, Olga Garcia, Ricardo Sanchez, Esperanza Such, Susana Barrena, Juana Ciudad, Beatriz Soriano, Rocio Benito, Gayane Avetisyan, Eva Lumbreras, Cristina Miguel-García, Sandra Santos-Mínguez, Lurdes Zamora, Mar Mallo, Celia González-Gil, Eulàlia Genescà, Thaysa Lopes, Jesus Maria Hernández-Rivas, Alberto Orfao, Josep-Maria Ribera
Journal: Blood
Blood (2022) 140 (Supplement 1): 6345–6347.
https://doi.org/10.1182/blood-2022-162159
Published: 2022
Journal Articles

Overactivation of the NLRP3 Inflammasome in Chronic Myelomonocytic Leukemia KRAS Mutated Patients Can be Detected By the Apoptosis-Associated Speck-like Protein (ASC) and Reverted By IL1β Inhibitors

Laura Hurtado-Navarro, Ernesto J Cuenca, Eva Soler, Andres Jerez, Helios Martínez-Banaclocha, Esperanza Such, Beatriz Bellosillo, Lurdes Zamora, Jesus Maria Hernández-Rivas, Javier Marco, Laura Martínez-Alarcón, María Dolores Linares-Latorre, Josefa Marco, Sara García Ávila, Paula Amat, Teresa González, Marta Martín Izquierdo, Montserrat Arnan Sangerman, Helena Pomares, Tzu Hua Chen-Liang, Maite Herranz, Gonzalo Carreño, Carlos Garcia-Palenciano, Raul Teruel Montoya, Pablo Pelegrin, Francisca Ferrer Marin
Journal: Blood
Blood (2021) 138 (Supplement 1): 3670.
https://doi.org/10.1182/blood-2021-153686
Published: 2021
Journal Articles

Myelodysplastic Syndromes with 20q Deletion: Incidence, Prognostic Value and Impact on Response to Azacitidine of ASXL1 Chromosomal Deletion and Genetic Mutations

Iván Martín, PhD, Eva Villamón, PhD, Rosario Abellán, PhD, Maria Jose Calasanz, PhD BSc, Aroa Irigoyen, PhD, Guillermo F Sanz, MD PhD, Esperanza Such, PhD, Elvira Mora Casterá, MD, Míriam Gutiérrez, PhD, Rosa Collado, MD, Míriam Vara, PhD, Laura Blanco, MD, Itziar Oiartzabal, MD, Sara Álvarez, PhD, Teresa Bernal del Castillo, MD PhD, Isabel Granada, PhD, Blanca Xicoy, MD, Lurdes Zamora, PhD, Andres Jerez, MDPhD, Raquel Fernández, PhD, Marisa Calabuig, MD, Francisca García, Alejandro Sanz, MD, Rosana Díez, MD, Ángela Gil, MD, Raquel de Paz, MD, Francisca López, MD, Teresa González, MD, Carlos Solano, MD PhD, Mar Tormo, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 1–2.
https://doi.org/10.1182/blood-2020-139588
Published: 2020
Journal Articles

Germinal Predisposition in Myelodysplastic Syndromes in Young Adults without a Preexisting Disorder or Organ Dysfunction: Identification of Deleterious Variants in Microsatellite Instability Genes

Tzu Hua Chen-Liang, Ana M Hurtado López, María Zurdo, Esperanza Such, Raul Teruel-Montoya, PhD, Laura Palomo, María-José Jimenez, MD, Rafael Andres del Orbe Barreto, Blanca Navarro, MD PhD, Félix López Cadenas, MD, Eduardo José Salido, MD, Carmen Benet, MD, Begoña Muiña, Raquel de Oña, Nuria de Haro, Fernando Ramos, Montserrat Arnan Sangerman, Francisca Maria Hernandez, MD, Francisco José Ortuño, Leonor Senent, Ana Vicente, María Díez-Campelo, MD PhD, Maria Lourdes Hermosin, MD, Teresa Bernal Del Castillo, MD PhD, Mar Tormo, MD PhD, Beatriz Arrizabalaga, Blanca Xicoy, MD MSc, José Cervera, MD PhD, Francesc Sole, PhD, Guillermo F. Sanz, MD PhD, Andres Jerez
Journal: Blood
Blood (2019) 134 (Supplement_1): 4226.
https://doi.org/10.1182/blood-2019-127204
Published: 2019
Journal Articles

Clinical Characteristics and Cardioavscular Events in Patients with Esential Thrombocythemia with <10% Vs. ≥10% JAK2 V617F Allele Burden

Blanca Xicoy, MD MSc, Natalia Estrada, Alberto Alvarez-Larran, Xavier Calvo Gonzalez, Beatriz Bellosillo, Arenillas Leonor, Iván Martín, Juan Carlos Hernandez Boluda, Vicente Vicente, MD PhD, Andrea Espasa, Francisca Ferrer Marin, MD PhD, Gonzalo Caballero, MD, Valle Recanses Flores, MD, María Teresa Gómez-Casares, MD PhD, Marisol Xandri, Beatriz Cuevas, MD, Jose Maria Alonso Alonso, Manuel Pérez, Dr., Maribel Mata, Venancio Conesa, Carmen Albo, MD, Victor Marco, Juan-Manuel Alonso, Maria Laura Fox, MD, Raul Perez, M Jesús Rodriguez Domínguez, Valentin Garcia Gutierrez, MD PhD, Marina Gordillo, MD, Maria DOLORES Carrera, MD, Esperanza Such, Carlos Fernández, Lurdes Zamora, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4171.
https://doi.org/10.1182/blood-2019-126980
Published: 2019
Journal Articles

Germline and Acquired Genetic Variants in Myelodysplastic Syndromes in Young Adults without a Preexisting Disorder or Organ Dysfunction

Tzu Hua Chen-Liang, Ana M Hurtado López, Laura Palomo, MSc, Teresa Bernal Del Castillo, MD PhD, Mar Tormo, Maria Lourdes Hermosin, MD, María-José Jimenez, Navarro Blanca, Esperanza Such, Rafael Andres DEL Orbe Barreto, Nuria de Haro, Félix López Cadenas, MD, Begoña Muiña, Raquel de Oña, Carmen Benet, Eduardo José Salido, MD, Raul Teruel-Montoya, Fernando Ramos, Leonor Senent, Maria Díez-Campelo, Beatriz Arrizabalaga, MD PhD, Blanca Xicoy, Francisco José Ortuño, Francesc Solé, PhD, Guillermo Sanz, Andres Jerez
Journal: Blood
Blood (2018) 132 (Supplement 1): 4339.
https://doi.org/10.1182/blood-2018-99-116045
Published: 2018
Journal Articles

Preexisting Mutations in Hematopoietic Stem Cells in Patients with Therapy-Related Myeloid Neoplasms

Mariam Ibañez, Maria López-Pavía, Esperanza Such, Blanca Navarro, Alexander Neef, PhD, Javier Marco, Mireia Boluda-Navarro, Marta Llop, Claudia Sargas, Beatricce De Matteo, Alessandro Liquori, PhD, Elisa Gonzalez, Andres Jerez, David Valcárcel, Julia Montoro, Maria Díez-Campelo, Jesús-María Hernández-Rivas, MD PhD, Jesus M Hernández-Sánchez, Teresa Bernal Del Castillo, MD PhD, Alejandra Sanjuan, PhD, Pau Montesinos, MD PhD, Eva Barragán, Miguel A. Sanz, MD, José Cervera, MD PhD, Guillermo Sanz, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3956.
https://doi.org/10.1182/blood.V130.Suppl_1.3956.3956
Published: 2017
Journal Articles

A Novel Single Next-Generation Sequencing (NGS) Approach for the Molecular Karyotyping and Genotyping of Patients with Myelodysplastic Syndromes

Alessandro Liquori, PhD, Esperanza Such, Laura Palomo, MSc, Ivan Lesende, Alexander Neef, PhD, Mariam Ibañez, Gayane Avetisyan, Desiré Company, Sarah Moreau, Laia Pedrola, PhD, Jorge Selles, Ana Saus, Javi Ayala, Pamela Acha, Alejandra Sanjuan, PhD, Mireia Boluda, Beatrice De Matteo, Elisa Gonzalez, Miguel A. Sanz, MD, Francesc Sole, PhD, Guillermo Sanz, MD, José Cervera, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1700.
https://doi.org/10.1182/blood.V130.Suppl_1.1700.1700
Published: 2017
Journal Articles

Rapid Screening of Targetable Kinase Gene Fusions in Acute Lymphoblastic Leukemia

Esperanza Such, Gayane Avetisyan, Iván Martín, Inés Gómez-Seguí, PhD, Francisca García, Eva Villamón, PhD, Alessandro Liquori, PhD, Francisco Mares, MD, Marta Llop, Paula Amat, MDPhD, Mariam Ibañez, Eva Barragán, Mar Tormo, MD PhD, Guillermo Sanz, MD, Carlos Solano, MD PhD, José Cervera, MD PhD, Blanca Navarro, Miguel A. Sanz, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1436.
https://doi.org/10.1182/blood.V130.Suppl_1.1436.1436
Published: 2017
Journal Articles

Comparison of the Molecular Spectrum of Lenalidomide-Treated Myelodysplastic Syndrome with and without Del(5q)

Vera Adema, PhD, Laura Palomo, MSc, Francisco Fuster-Tormo, MSc, Rocío Benito, PhD, Rocio Salgado, PhD, Esperanza Such, PhD, Olivier Kosmider, PharmD, PhD, Maria Jose Larrayoz, MD, Blanca Xicoy, MD, Kamila Janusz, Paolo Maietta, Alexander Neef, PhD, Beatriz Arrizabalaga Amunchastegui, MD PhD, Michaela Fontenay, MD PhD, Paula Gomez-Marzo, MSc, Monica Del Rey, PhD, Mariam Ibáñez, PhD, Nuri Haro, Mar Mallo, PhD, Lurdes Zamora, PhD, Valeria Visconte, PhD, Jaroslaw P. Maciejewski, MD, PhD, FACP, Pierre Fenaux, MD PhD, Jose Cervera, MD PhD, Maria Jose Calasanz, BSc, PhD, Jesús María Hernández-Rivas, MD, Juan Cigudosa, PhD, Francesc Sole, PhD
Journal: Blood
Blood (2016) 128 (22): 3172.
https://doi.org/10.1182/blood.V128.22.3172.3172
Published: 2016