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Carlo Finelli
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Journal Articles

Molecular taxonomy of myelodysplastic syndromes and its clinical implications

Clinical Trials & Observations
Elsa Bernard, Robert P. Hasserjian, Peter L. Greenberg, Juan E. Arango Ossa, Maria Creignou, Heinz Tuechler, Jesus Gutierrez-Abril, Dylan Domenico, Juan S. Medina-Martinez, Max Levine, Konstantinos Liosis, Noushin Farnoud, Maria Sirenko, Martin Jädersten, Ulrich Germing, Guillermo Sanz, Arjan A. van de Loosdrecht, Yasuhito Nannya, Olivier Kosmider, Matilde Y. Follo, Felicitas Thol, Lurdes Zamora, Ronald F. Pinheiro, Andrea Pellagatti, Harold K. Elias, Detlef Haase, Christina Ganster, Lionel Ades, Magnus Tobiasson, Laura Palomo, Matteo Giovanni Della Porta, Pierre Fenaux, Monika Belickova, Michael R. Savona, Virginia M. Klimek, Fabio P. S. Santos, Jacqueline Boultwood, Ioannis Kotsianidis, Valeria Santini, Francesc Solé, Uwe Platzbecker, Michael Heuser, Peter Valent, Carlo Finelli, Maria Teresa Voso, Lee-Yung Shih, Michaela Fontenay, Joop H. Jansen, José Cervera, Norbert Gattermann, Benjamin L. Ebert, Rafael Bejar, Luca Malcovati, Seishi Ogawa, Mario Cazzola, Eva Hellström-Lindberg, Elli Papaemmanuil
Journal: Blood
Blood (2024) 144 (15): 1617–1632.
https://doi.org/10.1182/blood.2023023727
Published: 2024
Includes: Supplemental data
Journal Articles

Molecular and clinical presentation of UBA1 -mutated myelodysplastic syndromes

Brief Report
Maria Sirenko, Elsa Bernard, Maria Creignou, Dylan Domenico, Andrea Farina, Juan E. Arango Ossa, Olivier Kosmider, Robert Hasserjian, Martin Jädersten, Ulrich Germing, Guillermo Sanz, Arjan A. van de Loosdrecht, Carmelo Gurnari, Matilde Yung Follo, Felicitas Thol, Lurdes Zamora, Ronald Feitosa Pinheiro, Andrea Pellagatti, Harold K. Elias, Detlef Haase, Birgitta Sander, Elisa Orna, Katharina Zoldan, Lea Naomi Eder, Wolfgang R. Sperr, Renate Thalhammer, Christina Ganster, Lionel Adès, Magnus Tobiasson, Laura Palomo, Matteo Giovanni Della Porta, Kety Huberman, Pierre Fenaux, Monika Belickova, Michael R. Savona, Virginia M. Klimek, Fabio P. S. Santos, Jacqueline Boultwood, Ioannis Kotsianidis, Valeria Santini, Francesc Solé, Uwe Platzbecker, Michael Heuser, Peter Valent, Carlo Finelli, Maria Teresa Voso, Lee-Yung Shih, Seishi Ogawa, Michaela Fontenay, Joop H. Jansen, Jose Cervera, Benjamin L. Ebert, Rafael Bejar, Peter L. Greenberg, Norbert Gattermann, Luca Malcovati, Mario Cazzola, David B. Beck, Eva Hellström-Lindberg, Elli Papaemmanuil
Journal: Blood
Blood (2024) 144 (11): 1221–1229.
https://doi.org/10.1182/blood.2023023723
Published: 2024
Includes: Supplemental data
Journal Articles

Molecular Taxonomy of Myelodysplastic Syndromes and Its Clinical Implications

Elsa Bernard, Robert Hasserjian, Peter L. Greenberg, Juan E Arango Ossa, Maria Creignou, Yasuhito Nannya, Heinz Tuechler, Juan S Medina-Martínez, Max F Levine, Martin Jädersten, Ulrich Germing, Guillermo Sanz, Arjan A. van de Loosdrecht, Olivier Kosmider, Matilde Yung Follo, Felicitas Thol, Lurdes Zamora, Ronald Feitosa Pinheiro, Andrea Pellagatti, Harold K Elias, Detlef Haase, Maria Sirenko, Christina Ganster, Lionel Ades, Magnus Tobiasson, Laura Palomo, Matteo Giovanni Della Porta, Pierre Fenaux, Monika Belickova, Michael R. Savona, Virginia M. Klimek, Fabio P. S. Santos, Jacqueline Boultwood, Ioannis Kotsianidis, Valeria Santini, Francesc Sole, Uwe Platzbecker, Michael Heuser, Peter Valent, Carlo Finelli, Maria Teresa Voso, Lee-Yung Shih, Michaela Fontenay, Joop H. Jansen, Jose Cervera, Norbert Gattermann, Benjamin L. Ebert, Rafael Bejar, Luca Malcovati, Mario Cazzola, Seishi Ogawa, Eva Hellstrom Lindberg, Elli Papaemmanuil
Journal: Blood
Blood (2023) 142 (Supplement 1): 997.
https://doi.org/10.1182/blood-2023-186863
Published: 2023
Journal Articles

Bone Marrow Microenvironment As a Potential Key Regulator of Hematopoietic Cells Stemness in Myelodysplastic Syndromes (MDS)

Irene Casalin, Alessia De Stefano, Alessandra Cappellini, Eleonora Ceneri, Martina Lops, Andrea Pellagatti, Jacqueline Boultwood, Michele Cavo, Stefano Ratti, Lucia Manzoli, Lucio Cocco, Marilena Ciciarello, Miriam Fogli, Stefania Paolini, Sarah Parisi, Antonio Curti, Carlo Finelli, Matilde Yung Follo
Journal: Blood
Blood (2023) 142 (Supplement 1): 6463.
https://doi.org/10.1182/blood-2023-179914
Published: 2023
Journal Articles

UBA1 Mutations Identify a Rare but Distinct Subtype of Myelodysplastic Syndromes

Maria Sirenko, Elsa Bernard, Maria Creignou, Dylan Domenico, Andrea Farina, Juan E Arango Ossa, Olivier Kosmider, Robert Hasserjian, Martin Jädersten, Ulrich Germing, Guillermo Sanz, Arjan A. van de Loosdrecht, Carmelo Gurnari, Matilde Yung Follo, Felicitas Thol, Lurdes Zamora, Andrea Pellagatti, Harold K Elias, Detlef Haase, Christina Ganster, Lionel Ades, Magnus Tobiasson, Laura Palomo, Matteo Giovanni Della Porta, Kety Huberman, Pierre Fenaux, Monika Belickova, Michael R. Savona, Virginia M. Klimek, Fabio P. S. Santos, Jacqueline Boultwood, Ioannis Kotsianidis, Valeria Santini, Francesc Sole, Uwe Platzbecker, Michael Heuser, Peter Valent, Carlo Finelli, Maria Teresa Voso, Lee-Yung Shih, Seishi Ogawa, Michaela Fontenay, Joop H. Jansen, Jose Cervera, Benjamin L. Ebert, Rafael Bejar, Peter L. Greenberg, Norbert Gattermann, Luca Malcovati, Mario Cazzola, David B Beck, Eva Hellstrom Lindberg, Elli Papaemmanuil
Journal: Blood
Blood (2023) 142 (Supplement 1): 1862.
https://doi.org/10.1182/blood-2023-182949
Published: 2023
Journal Articles

Incidence, Clinical Associations, and Co-Mutation Patterns of UBA1 Mutations in MDS

Maria Sirenko, Elsa Bernard, David B. Beck, Maria Creignou, Dylan Domenico, Andrea Farina, Juan E Arango, Olivier Kosmider, Robert P. Hasserjian, Martin Jadersten, Ulrich Germing, Guillermo Sanz, Arjan A. van de Loosdrecht, Matilde Y Follo, Felicitas R. Thol, Lurdes Zamora, Ronald Feitosa Pinheiro, Andrea Pellagatti, Harold K. Elias, Detlef Haase, Christina Ganster, Lionel Ades, Magnus Tobiasson, Laura Palomo, Matteo G. Della Porta, Kety Huberman, Pierre Fenaux, Monika Belickova, Michael R. Savona, Virginia M. Klimek, Fabio Pires de Souza Santos, Jacqueline Boultwood, Ioannis Kotsianidis, Valeria Santini, Francesc Solé, Uwe Platzbecker, Michael Heuser, Peter Valent, Carlo Finelli, Maria Teresa Voso, Lee-Yung Shih, Seishi Ogawa, Michaela Fontenay, Joop H. Jansen, Jose Cervera, Benjamin L. Ebert, Rafael Bejar, Peter L Greenberg, Norbert Gattermann, Luca Malcovati, Mario Cazzola, Eva Hellström-Lindberg, Elli Papaemmanuil
Journal: Blood
Blood (2022) 140 (Supplement 1): 9785–9788.
https://doi.org/10.1182/blood-2022-162397
Published: 2022
Journal Articles

DNA Methylation Profiles Capture Clinical and Molecular Heterogeneity of MDS and Can be Harnessed for the Development of Robust Biomarkers Predictive of Response to Azacitidine

Qin Yang, Alice Brogi, Elizabeth A. Griffiths, Matilde Y Follo, Carlo Finelli, Jerald P. Radich, Michael J Rauh, Mikkael A. Sekeres, Rafael Bejar, Valeria Santini, Maria Ken E. Figueroa
Journal: Blood
Blood (2022) 140 (Supplement 1): 9769–9770.
https://doi.org/10.1182/blood-2022-163704
Published: 2022
Journal Articles

Venetoclax Rapidly and Strongly Enhances the Phospholipase C Response to Azacitidine Therapy in Myelodysplastic Syndromes

Matilde Y Follo, Alessia De Stefano, Sara Mongiorgi, Irene Casalin, Alessandra Cappellini, Stefano Ratti, Andrea Pellagatti, Miriam Fogli, Michele Cavo, Lucia Manzoli, Lucio Cocco, Jacqueline Boultwood, Sarah Parisi, Stefania Paolini, Antonio Curti, Carlo Finelli
Journal: Blood
Blood (2022) 140 (Supplement 1): 6905–6906.
https://doi.org/10.1182/blood-2022-163628
Published: 2022
Journal Articles

Neutrophil and platelet increases with luspatercept in lower-risk MDS: secondary endpoints from the MEDALIST trial

Clinical Trials & Observations
Guillermo Garcia-Manero, Ghulam J. Mufti, Pierre Fenaux, Rena Buckstein, Valeria Santini, María Díez-Campelo, Carlo Finelli, Osman Ilhan, Mikkael A. Sekeres, Amer M. Zeidan, Rodrigo Ito, Jennie Zhang, Anita Rampersad, Daniel Sinsimer, Jay T. Backstrom, Uwe Platzbecker, Rami S. Komrokji
Journal: Blood
Blood (2022) 139 (4): 624–629.
https://doi.org/10.1182/blood.2021012589
Published: 2022
Journal Articles

Efficacy and Safety of Eltrombopag Combined with Cyclosporine As First-Line Therapy in Adults with Severe Acquired Aplastic Anemia: Results of the Interventional Phase 2 Single-Arm Soar Study

Carlos Vallejo, Jun Ho Jang, Carlo Finelli, Efreen Montaño Figueroa, Lalita Norasetthada, Rodrigo T. Calado, Mehmet Turgut, Regis Peffault De Latour, Ulrike Kriemler-Krahn, Jens Haenig, Joan Maier, Phillip Scheinberg
Journal: Blood
Blood (2021) 138 (Supplement 1): 2174.
https://doi.org/10.1182/blood-2021-147733
Published: 2021
Journal Articles

Role of Mir-192-5p during Response to Azacitidine and Lenalidomide Therapy in Myelodysplastic Syndromes

Matilde Y Follo, Alessia De Stefano, Sara Mongiorgi, Valentina Indio, Annalisa Astolfi, Stefano Ratti, Andrea Pellagatti, Miriam Fogli, Andrea Pession, Michele Cavo, Lucia Manzoli, Lucio Cocco, Jacqueline Boultwood, Sarah Parisi, Stefania Paolini, Carlo Finelli
Journal: Blood
Blood (2021) 138 (Supplement 1): 3673.
https://doi.org/10.1182/blood-2021-149183
Published: 2021
Journal Articles

Azacitidine and Lenalidomide in Higher-Risk Myelodysplastic Syndromes. Long-Term Results of a Randomized Phase II Multicenter Study and Impact of Cytogenetic Scores and Mutational Status on Long-Lasting Responses

Carlo Finelli, Sarah Parisi, MDPhD, Matilde Y Follo, PhD, Cristina Clissa, MD, Miriam Fogli, PhD, Sara Mongiorgi, PhD, Costanza Bosi, MD, Isabella Capodanno, MD, Barbara Castagnari, MD, Anna Candoni, Monica Crugnola, MD, Maria Benedetta Giannini, MD, Giovanna Leonardi, Maurizio Miglino, PhD, Gian Matteo Rigolin, Domenico Russo, MD, Patrizia Tosi, Andrea Pellagatti, Jacqueline Boultwood, Lucio Cocco, MD, Michele Cavo
Journal: Blood
Blood (2020) 136 (Supplement 1): 45.
https://doi.org/10.1182/blood-2020-138371
Published: 2020
Journal Articles

Sequential Analysis of miRNA Profiling during Azacitidine and Lenalidomide Therapy in Myelodysplastic Syndromes

Matilde Y Follo, PhD, Sara Mongiorgi, PhD, Alessia De Stefano, BSc, Valentina Indio, PhD, Annalisa Astolfi, PhD, Andrea Pellagatti, Stefano Ratti, MD, Miriam Fogli, PhD, Sarah Parisi, MDPhD, Andrea Pession, Michele Cavo, Lucia Manzoli, MD, Lucio Cocco, MD, Jacqueline Boultwood, Carlo Finelli
Journal: Blood
Blood (2020) 136 (Supplement 1): 6–7.
https://doi.org/10.1182/blood-2020-136942
Published: 2020
Journal Articles

Efficacy and Safety of Luspatercept Treatment in Patients with Myelodysplastic Syndrome/Myeloproliferative Neoplasm with Ring Sideroblasts and Thrombocytosis (MDS/MPN-RS-T): A Retrospective Analysis from the Medalist Study

Rami S. Komrokji, MD, Uwe Platzbecker, Pierre Fenaux, MD PhD, Guillermo Garcia-Manero, MD, Ghulam J. Mufti, Professor, Valeria Santini, Maria Diez-Campelo, PhDMD, Carlo Finelli, Joseph G. Jurcic, MD, Peter L. Greenberg, Mikkael A. Sekeres, Amer M. Zeidan, MBBS, MHS, Amy E. DeZern, MD, Michael R. Savona, MD, Jeevan K. Shetty, Rodrigo Ito, George Zhang, Xianwei Ha, Daniel Sinsimer, Jay T. Backstrom, Amit Verma, MBBS
Journal: Blood
Blood (2020) 136 (Supplement 1): 13–15.
https://doi.org/10.1182/blood-2020-137232
Published: 2020
Journal Articles

TP53 State Dictates Genome Stability, Clinical Presentation and Outcomes in Myelodysplastic Syndromes

Elsa Bernard, PhD, Yasuhito Nannya, MD PhD, Tetsuichi Yoshizato, MD PhD, Robert P. Hasserjian, MD, Ryunosuke Saiki, Yusuke Shiozawa, MD PhD, Sean M. Devlin, PhD, Heinz Tuechler, Araxe Sarian, Luca Malcovati, MD, Francesc Sole, PhD, Detlef Haase, MD, Maria Creignou, Max Levine, MS, Ulrich Germing, MD, Catherine Cargo, MB, FRCPath, Yanming Zhang, MD, Juan Medina, MS, Juan E. Arango Ossa, BS, Julie Schanz, MD PhD, Arjan van de Loosdrecht, MD PhD, Martin Jädersten, MD PhD, John M. Bennett, MD, Magnus Tobiasson, MD PhD, Olivier Kosmider, PharmD, PhD, Matilde Y Follo, PhD, Felicitas Thol, MD, Ronald F Pinheiro, MD, Valeria Santini, MD, Ioannis Kotsianidis, Jacqueline Boultwood, Fabio PS Santos, MD, Senji Kasahara, MD PhD, Takayuki Ishikawa, MD PhD, Hisashi Tsurumi, MD PhD, Akifumi Takaori-Kondo, MD PhD, Toru Kiguchi, Chantana Polprasert, MD, Virginia M. Klimek, MD, Michael R. Savona, MD, Monika Belickova, PhD, Christina Ganster, Lionel Ades, MD PhD, Matteo Giovanni Della Porta, MD, Alexandra Smith, PhD, Yesenia Werner, Minal A Patel, MPH, Agnes Viale, PhD, Katelynd Vanness, Donna S Neuberg, ScD, Kristen E. Stevenson, MS, Kamal Menghrajani, MD, Kelly Bolton, MD PhD, Pierre Fenaux, MD PhD, Andrea Pellagatti, Uwe Platzbecker, MD, Michael Heuser, MD, Peter Valent, MD, Shigeru Chiba, MD PhD, Yasushi Miyazaki, MD PhD, Carlo Finelli, Maria Teresa Voso, MD, Lee-Yung Shih, MD, Michaela Fontenay, MD PhD, Joop H. Jansen, PhD, José Cervera, MD PhD, Yoshiko Atsuta, MD PhD, Norbert Gattermann, MD, Benjamin L. Ebert, MD PhD, Rafael Bejar, MD PhD, Peter L Greenberg, MD, Mario Cazzola, MD, Eva Hellstrom Lindberg, MD PhD, Seishi Ogawa, MD PhD, Elli Papaemmanuil, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 675.
https://doi.org/10.1182/blood-2019-129392
Published: 2019
Journal Articles

Hematologic Improvement-Neutrophil and -Platelet in the MEDALIST Trial: Multilineage Data from a Phase 3, Randomized, Double-Blind, Placebo-Controlled Study of Luspatercept to Treat Anemia in Patients with Very Low-, Low-, or Intermediate-Risk Myelodysplastic Syndromes (MDS) with Ring Sideroblasts (RS) Who Require Red Blood Cell (RBC) Transfusions

Guillermo Garcia-Manero, MD, Ghulam J. Mufti, Pierre Fenaux, MD PhD, Rena Buckstein, MD FRCPC, Valeria Santini, MD, María Díez-Campelo, MD PhD, Carlo Finelli, Mario Cazzola, MD, Osman Ilhan, Mikkael A. Sekeres, MD MS, Alan F. List, MD, Abderrahmane Laadem, Rodrigo Ito, Jennie Zhang, Anita Rampersad, Daniel Sinsimer, Peter G. Linde, Uwe Platzbecker, MD, Rami Komrokji
Journal: Blood
Blood (2019) 134 (Supplement_1): 4243.
https://doi.org/10.1182/blood-2019-123048
Published: 2019
Journal Articles

Clinical Relevance of Individual Response to Iron Chelation Therapy (ICT) in Patients with Myelodysplastic Syndromes (MDS) and Transfusion Requirement

Roberto Latagliata, Pasquale Niscola, MD PhD, Esther Natalie Oliva, MD, Marta Riva, MD, Isabella Capodanno, MD, Antonio Volpe, MD, Federica Pilo, MD, Claudia Baratè, Alessia Campagna, MD, Anna Maria Pelizzari, Antonella Poloni, PhD MD, Chiara Sarlo, MD, Giovanna Mansueto, Anna Lina Piccioni, Serena Rosati, MD, Ida Carmosino, Antonella Carbone, MD, Lucia Tognazzi, Prassede Salutari, MD, Annalisa Mancini, Patrizia Cuffari, Elsa Pennese, MD, Susanna Fenu, Maria Antonietta Aloe Spiriti, MD, Sara Galimberti, MD PhD, Alfredo Molteni, MD, Enrico Balleari, Massimo Breccia, MD, Robin Foà, MD, Luca Maurillo, Carlo Finelli
Journal: Blood
Blood (2019) 134 (Supplement_1): 3010.
https://doi.org/10.1182/blood-2019-129902
Published: 2019
Journal Articles

Assessment of Longer-Term Efficacy and Safety in the Phase 3, Randomized, Double-Blind, Placebo-Controlled MEDALIST Trial of Luspatercept to Treat Anemia in Patients (Pts) with Revised International Prognostic Scoring System (IPSS-R) Very Low-, Low-, or Intermediate-Risk Myelodysplastic Syndromes (MDS) with Ring Sideroblasts (RS) Who Require Red Blood Cell (RBC) Transfusions

Pierre Fenaux, MD PhD, Ghulam J. Mufti, Rena Buckstein, MD FRCPC, Valeria Santini, MD, María Díez-Campelo, MD PhD, Carlo Finelli, Mario Cazzola, MD, Osman Ilhan, MD, Mikkael A. Sekeres, MD MS, Rami S. Komrokji, MD, Alan F. List, MD, Amer M. Zeidan, MBBS, MHS, Amit Verma, MBBS, Abderrahmane Laadem, Rodrigo Ito, Jennie Zhang, Anita Rampersad, Daniel Sinsimer, Peter G. Linde, Guillermo Garcia-Manero, MD, Uwe Platzbecker, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 841.
https://doi.org/10.1182/blood-2019-123064
Published: 2019
Journal Articles

Negative Prognostic Relevance of a Specific 3-Gene Cluster in Myelodysplastic Syndromes during Azacitidine and Lenalidomide Therapy

Matilde Y Follo, PhD, Andrea Pellagatti, PhD, Richard N Armstrong, PhD, Stefano Ratti, MD, Sara Mongiorgi, PhD, Annalisa Astolfi, PhD, Valentina Indio, PhD, Maria Teresa Bochicchio, Cristina Clissa, MD PhD, Domenico Russo, MD, Marco Gobbi, MD, Sarah Parisi, Miriam Fogli, PhD, Giovanni Martinelli, Andrea Pession, MD, Michele Cavo, MD, Lucia Manzoli, MD, Lucio Cocco, MD, Jacqueline Boultwood, PhD, Carlo Finelli, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4347.
https://doi.org/10.1182/blood-2018-99-112062
Published: 2018
Journal Articles

Comparison of Two Different Therapeutic Regimens with Azacitidine and Lenalidomide (Combined versus Sequential) in Higher-Risk Myelodysplastic Syndromes. Update of Long-Term Results of a Randomized Phase II Multicenter Study

Carlo Finelli, MD, Cristina Clissa, MD, Matilde Y Follo, PhD, Sarah Parisi, Miriam Fogli, PhD, Sara Mongiorgi, PhD, Isabella Capodanno, Costanza Bosi, MD, Barbara Castagnari, MD, Anna Candoni, MD, Monica Crugnola, MD, Maria Benedetta Giannini, MD, Marco Gobbi, MD, Giovanna Leonardi, Gian Matteo Rigolin, Domenico Russo, MD, Patrizia Tosi, MD, Andrea Pellagatti, PhD, Jacqueline Boultwood, PhD, Lucio Cocco, MD, Michele Cavo, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4365.
https://doi.org/10.1182/blood-2018-99-117714
Published: 2018