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Journal Articles

Decitabine in older patients with AML: quality of life results of the EORTC-GIMEMA-GMDS-SG randomized phase 3 trial

Clinical Trials & Observations
Fabio Efficace, Michal Kicinski, Corneel Coens, Stefan Suciu, Walter J. F. M. van der Velden, Richard Noppeney, Sylvain Chantepie, Laimonas Griskevicius, Andreas Neubauer, Ernesta Audisio, Mario Luppi, Stephan Fuhrmann, Robin Foà, Martina Crysandt, Gianluca Gaidano, Radovan Vrhovac, Adriano Venditti, Eduardus F. M. Posthuma, Anna Candoni, Frédéric Baron, Olivier Legrand, Andrea Mengarelli, Paola Fazi, Marco Vignetti, Anne Giraut, Pierre W. Wijermans, Gerwin Huls, Michael Lübbert
Journal: Blood
Blood (2024) 144 (5): 541–551.
https://doi.org/10.1182/blood.2023023625
Published: 2024
Includes: Supplemental data
Journal Articles

Gimema Seifem Real-Life Study VS Randomized CPX-351 Registrative Trial for Older Patients with Secondary ACUTE Myeloid Leukemia: An Unanchored Matching-Adjusted Indirect Comparison of Infection Rates and Survival Outcomes

Luana Fianchi, Alfonso Piciocchi, Chiara Cattaneo, Fabio Guolo, Francesco Marchesi, Michele Gottardi, Francesco Restuccia, Anna Candoni, Elettra Ortu La Barbera, Rita Fazzi, Crescenza Pasciolla, Olimpia Finizio, Nicola Fracchiolla, Mario Delia, Federica Lessi, Michelina Dargenio, Valentina Bonuomo, Maria Ilaria Del Principe, Patrizia Zappasodi, Marco Picardi, Claudia Basilico, Monica Piedimonte, Paola Minetto, Marianna Criscuolo, Matteo Bonanni, Patrizia Chiusolo, Lucia Prezioso, Caterina Buquicchio, Lorella Maria Antonia Melillo, Daniele Zama, Francesca Farina, Antonio Giordano, Valentina Mancini, Irene Terrenato, Michela Rondoni, Andrea Bacigalupo, Alessandro Busca, Livio Pagano
Journal: Blood
Blood (2023) 142 (Supplement 1): 5845.
https://doi.org/10.1182/blood-2023-189358
Published: 2023
Journal Articles

Chronic Obstructive Pulmonary Disease and Previous Infections Have Impact on Infectious Complications in Patients with Chronic Lymphocytic Leukemia Treated with Venetoclax: A Multicentre Seifem Study

Francesco Autore, Andrea Visentin, Marina Deodato, Candida Vitale, Eugenio Galli, Alberto Fresa, Rita Fazzi, Alessandro Sanna, Jacopo Olivieri, Ilaria Scortechini, Maria Ilaria Del Principe, Paolo Sportoletti, Luana Schiattone, Nilla Maschio, Davide Facchinelli, Marta Coscia, Alessandra Tedeschi, Livio Trentin, Idanna Innocenti, Anna Candoni, Alessandro Busca, Livio Pagano, Luca Laurenti
Journal: Blood
Blood (2023) 142 (Supplement 1): 6529.
https://doi.org/10.1182/blood-2023-181037
Published: 2023
Journal Articles

Sequential Chemotherapy and Blinatumomab to Improve Minimal Residual Disease in Adult Ph- B-Lineage Acute Lymphoblastic Leukemia. Final Results of the Phase II Gimema LAL2317 Trial

Sabina Chiaretti, Irene Della Starza, Alessandra Santoro, Orietta Spinelli, Loredana Elia, Maria Stefania De Propris, Matteo Piccini, Patrizia Chiusolo, Felicetto Ferrara, Patrizia Zappasodi, Erika Borlenghi, Catello Califano, Monica Bocchia, Elisa Mauro, Fabrizio Pane, Anna Candoni, Albana Lico, Ernesta Audisio, Monia Lunghi, Anna Maria Mianulli, Mariangela Di Trani, Valentina Arena, Monica Messina, Alfonso Piciocchi, Paola Fazi, Alessandro Rambaldi, Robin Foà, Renato Bassan
Journal: Blood
Blood (2023) 142 (Supplement 1): 826.
https://doi.org/10.1182/blood-2023-174973
Published: 2023
Journal Articles

Impact of COVID-19 in Patients with Chronic Lymphocytic Leukemia Treated with Venetoclax: A Possible Role of the Association to Anti-CD20 Antibody? a Multicentre Seifem Study

Francesco Autore, Andrea Visentin, Marina Deodato, Candida Vitale, Eugenio Galli, Alberto Fresa, RITA Fazzi, Alessandro Sanna, Jacopo Olivieri, Ilaria Scortechini, Maria Ilaria Del Principe, Paolo Sportoletti, Luana Schiattone, Nilla Maschio, Davide Facchinelli, Marta Coscia, Alessandra Tedeschi, Livio Trentin, Idanna Innocenti, Anna Candoni, Alessandro Busca, Livio Pagano, Luca Laurenti
Journal: Blood
Blood (2023) 142 (Supplement 1): 3283.
https://doi.org/10.1182/blood-2023-180955
Published: 2023
Journal Articles

Measurable Residual Disease Assessment in Patients with Acute Myeloid Leukemia Aged ≥60 Years Treated with a 10-Day Decitabine Schedule Versus Intensive Chemotherapy in the AML21 Study (NCT02172872)

Adriano Venditti, Michal Kicinski, Ernesta Audisio, Mario Luppi, Gianluca Gaidano, Robin Foà, Anna Candoni, Andrea Mengarelli, Attilio Olivieri, Annalisa Imovilli, Maurizio Musso, Paolo De Fabritiis, Eliana Zuffa, Nicola Cascavilla, Agostino Tafuri, Maria Ilaria Del Principe, Stefan Suciu, Anne Giraut, Stéphanie Antunes, Pierre W. Wijermans, Michael Lübbert, Geert A. Huls, Marco Vignetti, Francesco Buccisano
Journal: Blood
Blood (2023) 142 (Supplement 1): 2948.
https://doi.org/10.1182/blood-2023-184851
Published: 2023
Journal Articles

Multicenter Campus ALL Study on Infectious Complications in Ph- Acute Lymphoblastic Leukemia Patients Treated in the Real Life with the Gimema LAL1913 Protocol

Patrizia Zappasodi, Ludovica Calabretta, Davide Lazzarotto, Marco Cerrano, Nicola Fracchiolla, Cristina Papayannidis, Monia Lunghi, Fabio Forghieri, Elisa Buzzatti, Michelina Dargenio, Crescenza Pasciolla, Marzia Defina, Fabio Guolo, Carla Mazzone, Elisa Roncoroni, Marianna Rossi, Sabina Chiaretti, Giovanni Pizzolo, Robin Foà, Anna Candoni
Journal: Blood
Blood (2023) 142 (Supplement 1): 5877.
https://doi.org/10.1182/blood-2023-182976
Published: 2023
Journal Articles

Novel Gene Mutations Associated with Disease-Free Survival in Elderly Patients with Acute Myeloid Leukemia Receiving First-Line Induction-Consolidation with or without Azacitidine Post-Remission Treatment

Esther Natalie Oliva, Maria Cuzzola, Anna Candoni, Prassede Salutari, Giuseppe Alberto Palumbo, Gianluigi Reda, Giuseppe Ianni', Giovanni Tripepi, Debora Capelli, Caterina Alati, Maria Concetta Cannatà, Pasquale Niscola, Bianca Serio, Santina Barillà, Pellegrino Musto, Ernesto Vigna, Lorella Maria Antonia Melillo, Rocco Tripepi, Ilaria Maria Delfino, Maria Elena Zannier, Yasuhito Nannya, Seishi Ogawa, Corrado Mammì
Journal: Blood
Blood (2023) 142 (Supplement 1): 6046.
https://doi.org/10.1182/blood-2023-186325
Published: 2023
Journal Articles

10-Day Decitabine Versus Intensive Chemotherapy Followed By Transplantation in Fit AML Patients Aged ≥60 Years: Health-Related Quality of Life Outcomes of the Randomized Phase III Trial AML21 of the EORTC Leukemia Group, Gimema, Celg, and Gmds-SG

Fabio Efficace, Gerwin A. Huls, Michal Kicinski, Walter JFM Van Der Velden, Richard Noppeney, Sylvain Chantepie, Laimonas Griskevicius, Andreas Neubauer, Ernesta Audisio, Mario Luppi, Stephan Fuhrmann, Robin Foà, Martina Crysandt, Gianluca Gaidano, Radovan Vrhovac, Adriano Venditti, Eduardus F.M. Posthuma, Anna Candoni, Frederic Baron, Olivier Legrand, Andrea Mengarelli, Marco Vignetti, Anne Giraut, Corneel Coens, Stefan Suciu, P.W. Wijermans, Michael Luebbert
Journal: Blood
Blood (2022) 140 (Supplement 1): 1281–1283.
https://doi.org/10.1182/blood-2022-166544
Published: 2022
Journal Articles

Gimema ALL2418: Interim Analysis of a Phase Iia Study of Feasibility and Effectiveness of Inotuzumab Ozogamicin in Adult Patients with B-Cell Acute Lymphoblastic Leukemia with Positive Minimal Residual Disease before Any Hematopoietic Stem Cell Transplantation

Giovanni Marconi, Alfonso Piciocchi, Sabina Chiaretti, Cristina Papayannidis, Monia Lunghi, Prassede Salutari, Patrizia Zappasodi, Alessandro Rambaldi, Attilio Olivieri, Maurizio Cavallari, Stefano Soddu, Nicola S Fracchiolla, Federica Gigli, Chiara Cattaneo, Daniele Giovanni Mattei, Anna Candoni, Giovanni Grillo, Maria Chiara Abbenante, Ernesta Audisio, Massimiliano Bonifacio, Albana Lico, Roberto Massimo Lemoli, Paolo De Fabritiis, Felicetto Ferrara, Martina Rachele Marino, Monica Messina, Anna Ferrari, Valentina Robustelli, Jacopo Nanni, Irene Della Starza, Giorgia Simonetti, Maria Stefania De Propris, Maria Teresa Bochicchio, Marco Vignetti, Paola Fazi, Giovanni Martinelli
Journal: Blood
Blood (2022) 140 (Supplement 1): 6119–6121.
https://doi.org/10.1182/blood-2022-157937
Published: 2022
Journal Articles

CPX-351 Induction in Secondary Acute Myeloblastic Leukemia: Extended Follow up from the Italian Compassionate Use Program

Paola Minetto, Fabio Guolo, Luana Fianchi, Marino Clavio, Michele Gottardi, Mauro Endri, Sara Galimberti, Giuliana Rizzuto, Margherita Sciumé, Michela Rondoni, Giambattista Bertani, Michelina Dargenio, Atto Billio, Barbara Scappini, Patrizia Zappasodi, Anna Maria Scattolin, Francesco Grimaldi, Giuseppe Pietrantuono, Pellegrino Musto, Cerrano Marco, Stefano D'Ardia, Ernesta Audisio, Alessandro Cignetti, Crescenza Pasciolla, Francesca Pavesi, Anna Candoni, Carmela Gurrieri, Monica Morselli, Caterina Alati, Nicola S Fracchiolla, Giovanni Rossi, Manuela Caizzi, Fabrizio Carnevale Schianca, Michele Cea, Agostino Tafuri, Giuseppe Rossi, Felicetto Ferrara, Livio Pagano, Roberto Massimo Lemoli
Journal: Blood
Blood (2021) 138 (Supplement 1): 1262.
https://doi.org/10.1182/blood-2021-153028
Published: 2021
Journal Articles

Posaconazole at Standard Dose Is Safe and More Effective Than Echinocandins As IFD Prophylaxis in Patients with FLT3 Mutated AML Treated with Midostaurin

Chiara Cattaneo, Francesco Marchesi, Valentina Bonuomo, Nicola S Fracchiolla, Anna Candoni, Marianna Criscuolo, Lucia Prezioso, Crescenza Pasciolla, Maria Ilaria Del Principe, Michelina Dargenio, Giuseppe Tarantini, Maria Enza Mitra, Francesca Farina, Federica Colnaghi, Mariarita Sciumè, Gianpaolo Nadali, Alessandro Busca, Giuseppe Rossi, Livio Pagano
Journal: Blood
Blood (2021) 138 (Supplement 1): 4381.
https://doi.org/10.1182/blood-2021-149080
Published: 2021
Journal Articles

Results of the 6-Year Follow-up of the Gimema AML1310 Trial: A Risk-Adapted, MRD-Directed Therapy for Young Adults with Newly Diagnosed Acute Myeloid Leukemia

Adriano Venditti, Alfonso Piciocchi, Raffaele Palmieri, Valentina Arena, Anna Candoni, Valeria Calafiore, Lorella MA Melillo, Roberto Cairoli, Paolo De Fabritiis, Gabriella Storti, Prassede Salutari, Francesco Lanza, Giovanni Martinelli, Mario Luppi, Saveria Capria, Luca Maurillo, Maria Ilaria Del Principe, Giovangiacinto Paterno, Elisa Buzzatti, Maria Teresa Voso, Tiziana Ottone, Maria irno Consalvo, Paola Fazi, Marco Vignetti, William Arcese, Sergio Amadori, Francesco Buccisano
Journal: Blood
Blood (2021) 138 (Supplement 1): 2359.
https://doi.org/10.1182/blood-2021-147200
Published: 2021
Journal Articles

Impact of Comorbidities on Prognosis of Elderly Patients with Acute Myeloid Leukemia Who Receive Hypomethylating Agents

Giovanni Marconi, Anna Candoni, Roberta di Nicola, Chiara Sartor, Sarah Parisi, Mariachiara Abbenante, Jacopo Nanni, Gianluca Cristiano, Davide Lazzarotto, Maria Benedetta Giannini, Carmen Baldazzi, Maria Chiara Fontana, Lorenza Bandini, Emanuela Ottaviani, Nicoletta Testoni, Chiara Di Giovanni Bezzi, Rania Abd-alatif, Renato Fanin, Giovanni Martinelli, Stefania Paolini, Michele Cavo, Cristina Papayannidis, Antonio Curti
Journal: Blood
Blood (2021) 138 (Supplement 1): 3373.
https://doi.org/10.1182/blood-2021-149459
Published: 2021
Journal Articles

ACUTE Lymphoblastic Leukemia (ALL) and COVID-19 Infection. a Campus ALL Report

Sabina Chiaretti, Massimiliano Bonifacio, Roberta Agrippino, Mario Annunziata, Anna Candoni, Cerrano Marco, Michele Cedrone, Maria Ciccone, Patrizia Chiusolo, Antonio Curti, Michelina Dargenio, Marzia Defina, Mario Delia, Maria Ilaria Del Principe, Mauro Endri, Carmen Fava, Fabio Forghieri, Alessandro Fiorentini, Fabio Giglio, Francesco Grimaldi, Fabio Guolo, Michela Lamanda, Monia Lunghi, Federico Lussana, Valentina Mancini, Carla Mazzone, Antonino Mulè, Crescenza Pasciolla, Matteo Piccini, Giovanna Rege Cambrin, Prassede Salutari, Lidia Santoro, Anna Maria Scattolin, Mariarita Sciumè, Elisabetta Todisco, Felicetto Ferrara, Giovanni Pizzolo, Robin Foà
Journal: Blood
Blood (2021) 138 (Supplement 1): 216.
https://doi.org/10.1182/blood-2021-150958
Published: 2021
Journal Articles

Azacitidine and Lenalidomide in Higher-Risk Myelodysplastic Syndromes. Long-Term Results of a Randomized Phase II Multicenter Study and Impact of Cytogenetic Scores and Mutational Status on Long-Lasting Responses

Carlo Finelli, Sarah Parisi, MDPhD, Matilde Y Follo, PhD, Cristina Clissa, MD, Miriam Fogli, PhD, Sara Mongiorgi, PhD, Costanza Bosi, MD, Isabella Capodanno, MD, Barbara Castagnari, MD, Anna Candoni, Monica Crugnola, MD, Maria Benedetta Giannini, MD, Giovanna Leonardi, Maurizio Miglino, PhD, Gian Matteo Rigolin, Domenico Russo, MD, Patrizia Tosi, Andrea Pellagatti, Jacqueline Boultwood, Lucio Cocco, MD, Michele Cavo
Journal: Blood
Blood (2020) 136 (Supplement 1): 45.
https://doi.org/10.1182/blood-2020-138371
Published: 2020
Journal Articles

Validation of ELN2017 Risk Stratification in a Post-Hoc Analysis of the Prospective Biomarker-Based Gimema AML1310 Protocol

Raffaele Palmieri, MD, Francesco Buccisano, MD, Alfonso Piciocchi, MS, Valentina Arena, MS, Anna Candoni, Lorella MA Melillo, MD, Valeria Calafiore, Roberto Cairoli, MD, Paolo De Fabritiis, MD, Gabriella Storti, Prassede Salutari, MD, Francesco Lanza, MD, Giovanni Martinelli, MD, Mario Luppi, Saveria Capria, MD, Luca Maurillo, Maria Ilaria Del Principe, Giovangiacinto Paterno, Maria Teresa Voso, MD, Tiziana Ottone, Serena Lavorgna, Paola Fazi, MD, Marco Vignetti, MD, William Arcese, MD PhD, Adriano Venditti, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 34–35.
https://doi.org/10.1182/blood-2020-139773
Published: 2020
Journal Articles

Intensive Fludarabine, High Dose Cytarabine and Idarubicin-Based Induction for Younger NPM1-Mutated AML Patient: Overcoming the Negative Prognosis of FLT3-ITD Mutation

Paola Minetto, MD PhD, Anna Candoni, Fabio Guolo, MD, Marino Clavio, MD, Maria Elena Zannier, MD, Maurizio Miglino, PhD, Maria Vittoria Dubbini, MD, Anna Sicuranza, PhD, Sara Ciofini, Elisabetta Tedone, Nicoletta Colombo, PhD, Girolamo Pugliese, Filippo Ballerini, MD, Michele Cea, Monica Bocchia, Renato Fanin, MD, Roberto Massimo Lemoli, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 32–33.
https://doi.org/10.1182/blood-2020-142887
Published: 2020
Journal Articles

Long Term Effects of Eltrombopag Treatment Versus Placebo for Low-Risk Myelodysplastic Syndromes with Thrombocytopenia (EQoL-MDS): Interim Results of a Single-Blind, Randomised, Controlled, Phase 2 Superiority Trial

Esther Natalie Oliva, MD, Caterina Alati, MD, Valeria Santini, MD, Antonella Poloni, PhD MD, Marta Riva, MD, Pasquale Niscola, MD PhD, Valentina Giai, MD, Grazia Sanpaolo, MD, Enrico Balleari, Elena Crisà, MD, Dario Ferrero, MD, Ulrich Germing, MD, Pierre Fenaux, MD PhD, Giuseppe A. Palumbo, MD PhD, Prassede Salutari, MD, Stefana Impera, MD, Isabella Capodanno, MD, Gianluigi Reda, MD, Anna Marina Liberati, Alfredo Molteni, MD, Giorgina Specchia, MD, Francesco Buccisano, MD, Maria Teresa Voso, MD, Stefano Mancini, MD, Monica Bocchia, Anna Candoni, MD, Bruno Martino, MD, Patrizia Cufari, Maria Grazia D'Errigo, Gina Zini, MD PhD, Roberto Latagliata
Journal: Blood
Blood (2019) 134 (Supplement_1): 3000.
https://doi.org/10.1182/blood-2019-126744
Published: 2019
Journal Articles

Azacitidine for Post-Remission Therapy in Elderly Patients with Acute Myeloid Leukemia : Final Results of the Qoless AZA-Amle Randomized Trial

Esther Natalie Oliva, MD, Anna Candoni, MD, Prassede Salutari, MD, Francesco Di Raimondo, MD, Gianluigi Reda, MD, Debora Capelli, MD, Pasquale Niscola, MD PhD, Carmine Selleri, MD, Pellegrino Musto, MD, Ernesto Vigna, MD, Antonio Volpe, MD, Nicola Cascavilla, Donato Mannina, MD, Paola Carluccio, MD, Maria Elena Zannier, MD, Elisa Mauro, MD, Alessandra Freyrie, MD, Carla Mazzone, MD, Bruno Martino, MD, Caterina Alati, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 117.
https://doi.org/10.1182/blood-2019-125562
Published: 2019