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Journal Articles

CD49d Expression Is Included in a Revised 4-Factor Model Predicting Outcome in Patients with Chronic Lymphocytic Leukemia Treated with Ibrutinib: A Multi-Center Real-World Experience

Riccardo Bomben, Antonella Zucchetto, Roberta Laureana, Annalisa Chiarenza, Jacopo Olivieri, Erika Tissino, Francesca Rossi, Filippo Vit, Tamara Bittolo, Robel Papotti, Federico Pozzo, Annalisa Gaglio, Massimo Degan, Jerry Polesel, Roberto Marasca, Gianluigi Reda, Andrea Visentin, Riccardo Moia, Idanna Innocenti, Candida Vitale, Roberta Murru, Marzia Varettoni, Agostino Tafuri, Francesco Zaja, Massimiliano Postorino, Enrica Antonia Martino, Adalgisa Condolucci, Davide Rossi, Antonio Cuneo, Francesco Di Raimondo, Paolo Sportoletti, Ilaria Del Giudice, Robin Foa, Francesca Romana Mauro, Marta Coscia, Luca Laurenti, Gianluca Gaidano, Livio Trentin, Maria Ilaria Del Principe, Massimo Gentile, Valter Gattei
Journal: Blood
Blood (2023) 142 (Supplement 1): 3281.
https://doi.org/10.1182/blood-2023-174897
Published: 2023
Journal Articles

Measurable Residual Disease Assessment in Patients with Acute Myeloid Leukemia Aged ≥60 Years Treated with a 10-Day Decitabine Schedule Versus Intensive Chemotherapy in the AML21 Study (NCT02172872)

Adriano Venditti, Michal Kicinski, Ernesta Audisio, Mario Luppi, Gianluca Gaidano, Robin Foà, Anna Candoni, Andrea Mengarelli, Attilio Olivieri, Annalisa Imovilli, Maurizio Musso, Paolo De Fabritiis, Eliana Zuffa, Nicola Cascavilla, Agostino Tafuri, Maria Ilaria Del Principe, Stefan Suciu, Anne Giraut, Stéphanie Antunes, Pierre W. Wijermans, Michael Lübbert, Geert A. Huls, Marco Vignetti, Francesco Buccisano
Journal: Blood
Blood (2023) 142 (Supplement 1): 2948.
https://doi.org/10.1182/blood-2023-184851
Published: 2023
Journal Articles

Reappearance of CXCR4 dim /CD5 bright Proliferative Fraction Associates with BTK Mutations and Anticipates Progression in Ibrutinib-Treated CLL

Federico Pozzo, Gabriela Forestieri, Filippo Vit, Erika Tissino, Tamara Bittolo, Robel Papotti, Annalisa Gaglio, Lodovico Terzi Di Bergamo, Agostino Steffan, Roberta Laureana, Agostino Tafuri, Annalisa Chiarenza, Francesco Di Raimondo, Jacopo Olivieri, Francesco Zaja, Luca Laurenti, Maria Ilaria Del Principe, Riccardo Bomben, Antonella Zucchetto, Davide Rossi, Valter Gattei
Journal: Blood
Blood (2023) 142 (Supplement 1): 4627.
https://doi.org/10.1182/blood-2023-174906
Published: 2023
Journal Articles

International, Prospective Study Comparing Nilotinib Versus Imatinib with Early Switch to Nilotinib to Obtain Sustained Treatment-Free Remission in Patients with Chronic Myeloid Leukemia (SUSTRENIM trial): Analysis of the Eligibility to Treatment Discontinuation

Fabrizio Pane, Fausto Castagnetti, Alfonso Piciocchi, Elisabetta Abruzzese, Renato Bassan, Gianni Binotto, Massimiliano Bonifacio, Giovanni Caocci, Francesco Cavazzini, Giuseppe Cimino, Antonella Gozzini, Monia Lunghi, Roberto Marasca, Bruno Martino, Francesco Muriano, Gianantonio Rosti, Antonella Russo Rossi, Simona Sica, Agostino Tafuri, Daniele Vallisa, Monica Messina, Francesca Paola Paoloni, Paola Fazi, Peter E Westerweel, Jeroen J.W.M. Janssen, Giuseppe Saglio, Massimo Breccia
Journal: Blood
Blood (2023) 142 (Supplement 1): 3169.
https://doi.org/10.1182/blood-2023-182220
Published: 2023
Journal Articles

Copanlisib in Combination with Rituximab and Bendamustine for Transplant-Ineligible Relapsed/Refractory Diffuse Large B-Cell Lymphoma Patients: Results from the Phase II Multicenter Fil_Copa-Rb Trial from Fondazione Italiana Linfomi (FIL)

Pio Manlio Mirko Frascione, Mattia Novo, Alessia Castellino, Luigi Marcheselli, Samantha Deianira Dattoli, Alessandra Tucci, Guido Gini, Giuseppe Tarantini, Donato Mannina, Annalisa Arcari, Roberta Martiniani, Elisabetta Scarpa, Dario Marino, Michele Spina, Ausilia Giuseppa Gorgone, Nicola Di Renzo, Salvatrice Mancuso, Luigi Petrucci, Agostino Tafuri, Umberto Vitolo
Journal: Blood
Blood (2023) 142 (Supplement 1): 1728.
https://doi.org/10.1182/blood-2023-184718
Published: 2023
Journal Articles

An Unsupervised Machine Learning Method Stratifies Chronic Lymphocytic Leukemia Patients into Novel Categories with Different Risk of Early Treatment

Federico Pozzo, Francesca Cuturello, Edith Villegas Garcia, Francesca Rossi, Massimo Degan, Paola Nanni, Ilaria Cattarossi, Eva Zaina, Paola Varaschin, Alessandra Braida, Michele Berton, Laura Zannier, Filippo Vit, Erika Tissino, Tamara Bittolo, Roberta Laureana, Giovanni Francesco D'Arena, Luca Laurenti, Agostino Tafuri, Jacopo Olivieri, Francesco Zaja, Annalisa Chiarenza, Francesco Di Raimondo, Maria Ilaria Del Principe, Riccardo Bomben, Antonella Zucchetto, Alessio Ansuini, Chris Fegan, Chris Pepper, Andrea Pepper, Kari G. Rabe, Sameer A. Parikh, Neil E. Kay, Alberto Cazzaniga, Valter Gattei
Journal: Blood
Blood (2023) 142 (Supplement 1): 1892.
https://doi.org/10.1182/blood-2023-177884
Published: 2023
Journal Articles

Patients' Perception of Usability and Utility of a Digital Health Tool for Electronic Patient-Reported Outcomes Monitoring in Real-Life Hematology Practice: Evidence from the Gimema-Alliance Platform

Fabio Efficace, Mario Luppi, Leonardo Potenza, Francesco Sparano, Giovanni Caocci, Francesca Fazio, Massimo Breccia, Maria Teresa Petrucci, Andrea Patriarca, Thomas Baldi, Michelina Santopietro, Roberta Battistini, Agostino Tafuri, Gloria Margiotta Casaluci, Elisabetta Colaci, Davide Giusti, Valeria Pioli, Paolo De Fabritiis, Nicolina Rita Ardu, Pasquale Niscola, Olga Mulas, Claudio Fozza, Sergio Siragusa, Salvatrice Mancuso, Paola Boggione, Lorenzo De Paoli, Anna Paola Leporace, Maria Paola Bianchi, Ida Carmosino, Claudio Cartoni, Alice Di Rocco, Isabella Capodanno, Massimo Pini, Alessandra Romano, Paola Fazi, Marco Vignetti
Journal: Blood
Blood (2023) 142 (Supplement 1): 3714.
https://doi.org/10.1182/blood-2023-180574
Published: 2023
Journal Articles

Venetoclax and idasanutlin in relapsed/refractory AML: a nonrandomized, open-label phase 1b trial

Clinical Trials & Observations
Naval G. Daver, Monique Dail, Jacqueline S. Garcia, Brian A. Jonas, Karen W. L. Yee, Kevin R. Kelly, Norbert Vey, Sarit Assouline, Gail J. Roboz, Stefania Paolini, Daniel A. Pollyea, Agostino Tafuri, Joseph M. Brandwein, Arnaud Pigneux, Bayard L. Powell, Pierre Fenaux, Rebecca L. Olin, Giuseppe Visani, Giovanni Martinelli, Maika Onishi, Jue Wang, Weize Huang, Cherie Green, Marion G. Ott, Wan-Jen Hong, Marina Y. Konopleva, Michael Andreeff
Journal: Blood
Blood (2023) 141 (11): 1265–1276.
https://doi.org/10.1182/blood.2022016362
Published: 2023
Includes: Supplemental data
Journal Articles

An Unsupervised Machine Learning Method Stratifies Chronic Lymphocytic Leukemia Patients in Novel Categories with Different Risk of Early Treatment

Francesca Cuturello, Federico Pozzo, Edith Natalia Villegas Garcia, Francesca Maria Rossi, Massimo Degan, Paola Nanni, Ilaria Cattarossi, Eva Zaina, Paola Varaschin, Alessandra Braida, Michele Berton, Laura Zannier, Filippo Vit, Erika Tissino, Tamara Bittolo, Roberta Laureana, Giovanni D'Arena, Luca Laurenti, Agostino Tafuri, Jacopo Olivieri, Francesco Zaja, Annalisa Chiarenza, Maria Ilaria Del Principe, Riccardo Bomben, Antonella Zucchetto, Stefano Cozzini, Alessio Ansuini, Alberto Cazzaniga, Valter Gattei
Journal: Blood
Blood (2022) 140 (Supplement 1): 4111–4112.
https://doi.org/10.1182/blood-2022-159981
Published: 2022
Journal Articles

Impact of COVID-19 Pandemic Waves on Outcomes of Patients with Previously Untreated Advanced Follicular Lymphoma Enrolled in the Urban Ambispective Study in Italy

Antonio Pinto, Emanuele Guardalben, Marica Battista, Giulia Chiara Gazzoli, Michele Merli, Annalisa Chiarenza, Tommasina Perrone, Attilio Guarini, Nicola Di Renzo, Carlo Visco, Agostino Tafuri, Roberta Murru, Felicetto Ferrara, Jacopo Olivieri, Attilio Olivieri, Andrés J M Ferreri, Marco Ladetto, Pier Luigi Zinzani, Luca Arcaini, Giuseppe Gritti
Journal: Blood
Blood (2022) 140 (Supplement 1): 6504–6506.
https://doi.org/10.1182/blood-2022-166486
Published: 2022
Journal Articles

Real-World Outcome of Treatment with Single-Agent Ibrutinib in Patients with Chronic Lymphocytic Leukemia: Results from the Italian Study Evidence

Stefano Molica, Potito Rosario Scalzulli, Lydia Scarfò, Attilio Guarini, Roberta Murru, Paolo Sportoletti, Ferdinando Frigeri, Francesco Albano, Nicola Di Renzo, Alessandro Sanna, Idanna Innocenti, Massimo Massaia, Marta Coscia, Elsa Pennese, Caterina Patti, Gianluigi Reda, Agostino Tafuri, Giulia Regazzoni, Michele Di Candia, Francesca Romana Mauro
Journal: Blood
Blood (2022) 140 (Supplement 1): 4178–4180.
https://doi.org/10.1182/blood-2022-166140
Published: 2022
Journal Articles

Remarkable Remission Rate and Long-Term Efficacy of Upfront Metronomic Chemotherapy in Elderly/FRAIL Patients, with Diffuse Large B-Cell Lymphoma

M. Christina Cox, Sabrina Pelliccia, Paola Orlandi, Arianna Di Napoli, Gerardo Musuraca, Caterina Patti, Maria Paola Bianchi, Matteo Caridi, Marta Banchi, Roberta Battistini, Tiziana Lanzolla, Agostino Tafuri, Guido Bocci
Journal: Blood
Blood (2022) 140 (Supplement 1): 3796–3797.
https://doi.org/10.1182/blood-2022-165379
Published: 2022
Journal Articles

The CXCR4 dim /CD5 bright Proliferative Fraction Reappears in Relapsed CLL Under Ibrutinib, Enriched in BTK Mutations

Federico Pozzo, Gabriela Forestieri, Giulia Ianna, Filippo Vit, Erika Tissino, Tamara Bittolo, Lodovico Terzi Di Bergamo, Roberta Laureana, Agostino Tafuri, Annalisa Chiarenza, Francesco Di Raimondo, Jacopo Olivieri, Francesco Zaja, Luca Laurenti, Maria Ilaria Del Principe, Riccardo Bomben, Antonella Zucchetto, Davide Rossi, Valter Gattei
Journal: Blood
Blood (2022) 140 (Supplement 1): 4103–4104.
https://doi.org/10.1182/blood-2022-159947
Published: 2022
Journal Articles

CPX-351 Induction in Secondary Acute Myeloblastic Leukemia: Extended Follow up from the Italian Compassionate Use Program

Paola Minetto, Fabio Guolo, Luana Fianchi, Marino Clavio, Michele Gottardi, Mauro Endri, Sara Galimberti, Giuliana Rizzuto, Margherita Sciumé, Michela Rondoni, Giambattista Bertani, Michelina Dargenio, Atto Billio, Barbara Scappini, Patrizia Zappasodi, Anna Maria Scattolin, Francesco Grimaldi, Giuseppe Pietrantuono, Pellegrino Musto, Cerrano Marco, Stefano D'Ardia, Ernesta Audisio, Alessandro Cignetti, Crescenza Pasciolla, Francesca Pavesi, Anna Candoni, Carmela Gurrieri, Monica Morselli, Caterina Alati, Nicola S Fracchiolla, Giovanni Rossi, Manuela Caizzi, Fabrizio Carnevale Schianca, Michele Cea, Agostino Tafuri, Giuseppe Rossi, Felicetto Ferrara, Livio Pagano, Roberto Massimo Lemoli
Journal: Blood
Blood (2021) 138 (Supplement 1): 1262.
https://doi.org/10.1182/blood-2021-153028
Published: 2021
Journal Articles

Clinical Utility and Physician Perceptions of a Digital Platform for Electronic Patient-Reported Outcomes Monitoring in Patients with Hematologic Malignancies in Real-World Practice

Fabio Efficace, Massimo Breccia, Giovanni Caocci, Leonardo Potenza, Ida Carmosino, Francesca Fazio, Maria Teresa Petrucci, Isabella Capodanno, Francesco Cottone, Alice Di Rocco, Caterina Patti, Valeria Pioli, Elisabetta Colaci, Davide Giusti, Elisabetta Lugli, Luigi Rigacci, Michelina Santopietro, Fulvia Fanelli, Agostino Tafuri, Maria Paola Bianchi, Claudio Cartoni, Giusy Antolino, Esmeralda Conte, Edoardo La Sala, Massimo Pini, Claudio Fozza, Sergio Siragusa, Marco Santoro, Salvatrice Mancuso, Paolo De Fabritiis, Nicolina Rita Ardu, Pasquale Niscola, Andrea Patriarca, Ombretta Annibali, Mario Luppi, Paola Fazi, Marco Vignetti
Journal: Blood
Blood (2021) 138 (Supplement 1): 4017.
https://doi.org/10.1182/blood-2021-146508
Published: 2021
Journal Articles

The Use of Ibrutinib in Italian CLL Patients Treated in a Real-World Setting (EVIDENCE): A Preliminary Report

Stefano Molica, Potito Rosario Scalzulli, Lydia Scarfo, Attilio Guarini, Roberta Murru, Paolo Sportoletti, Ferdinando Frigeri, Francesco Albano, Nicola Di Renzo, Alessandro Sanna, Idanna Innocenti, Massimo Massaia, Marta Coscia, Elsa Pennese, Caterina Patti, Gianluigi Reda, Agostino Tafuri, Anna Grugnetti, Valeria Magarotto, Francesca Romana Mauro
Journal: Blood
Blood (2021) 138 (Supplement 1): 4684.
https://doi.org/10.1182/blood-2021-148378
Published: 2021
Journal Articles

The Accuracy of the International Myeloma Working Group Frailty Score in Capturing Health-Related Quality of Life Profile of Patients with Relapsed Refractory Multiple Myeloma

Fabio Efficace, Gianluca Gaidano, Maria Teresa Petrucci, Pasquale Niscola, Lucia Tognazzi, Elisabetta Antonioli, Francesco Cottone, Ombretta Annibali, Agostino Tafuri, Catello Califano, Alessandra Larocca, Leonardo Potenza, Giulia Palazzo, Claudio Fozza, Domenico Pastore, Gian Matteo Rigolin, Massimo Offidani, Alessandra Romano, Patrizia Tosi, Charalampia Kyriakou, Nicola Cascavilla, Stefano Molica, Alessandro Gozzetti, Daniele Derudas, Marco Vignetti, Michele Cavo
Journal: Blood
Blood (2021) 138 (Supplement 1): 115.
https://doi.org/10.1182/blood-2021-145977
Published: 2021
Journal Articles

Chronic Lymphocytic Leukemia Cells with Mutated Nfkbie Are Positively Selected By Microenvironmental Signals and Display Reduced Sensitivity to Ibrutinib Treatment

Alice Bonato, Riccardo Bomben, Supriya Chakraborty, Giulia Felician, Claudio Martines, Antonella Zucchetto, Annalisa Chiarenza, Giovanni Del Poeta, Roberto Marasca, Agostino Tafuri, Luca Laurenti, Aleksandar J. Dimovski, Valter Gattei, Dimitar G Efremov
Journal: Blood
Blood (2021) 138 (Supplement 1): 248.
https://doi.org/10.1182/blood-2021-149442
Published: 2021
Journal Articles

Sequential Treatments in Chronic Phase Chronic Myeloid Leukemia (CML) Patients without Optimal Response after Frontline Nilotinib or Dasatinib: An Italian CML Campus Study

Gabriele Gugliotta, MD PhD, Mario Annunziata, MD, Isabella Capodanno, MD, Davide Rapezzi, MD, Immacolata Attolico, MD, Iolanda Donatella Vincelli, Mario Tiribelli, MD, Alessandra Malato, MD PhD, Michele Pizzuti, MD, Vincenzo Accurso, MD, Massimiliano Bonifacio, MD, Sara Galimberti, MD PhD, Giuseppina Loglisci, MD, Elisabetta Abruzzese, MD, Monica Bocchia, Antonella Gozzini, MD, Micaela Bergamaschi, MD, Maria Cristina Miggiano, MD, Agostino Tafuri, MD, Grazia Sanpaolo, MD, Gianni Binotto, MD, Fausto Castagnetti, MDPhD, Giorgina Specchia, MD, Francesco Di Raimondo, MD, Michele Cavo, Gianantonio Rosti, MD, Robin Foà, MD, Giuseppe Saglio, MD PhD, Massimo Breccia, MD, Fabio Stagno, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 45–46.
https://doi.org/10.1182/blood-2020-141077
Published: 2020
Journal Articles

Do Not Miss Karyotyping at Chronic Myeloid Leukemia Diagnosis: An Italian Campus CML Study on the Role of Complex Variant Translocations

Massimiliano Bonifacio, MD, Chiara Elena, MD, Mariella D'Adda, MD, Luigi Scaffidi, MD, Mairi Pucci, MD, Fiorenza Aprili, Jacqueline Ferrari, MD, Alessandra Tucci, MD, Fabio Stagno, MD PhD, Anna Rita Scortechini, MD, Gianni Binotto, MD, Mario Annunziata, MD, Maria Cristina Miggiano, MD, Isabella Capodanno, MD, Sara Galimberti, MD PhD, Mario Tiribelli, MD, Emilia Giugliano, Giovanni Caocci, MD, Monica Crugnola, MD, Paola Ronchi, MD, Sabina Russo, MD, Martina Tinelli, MD, Agostino Tafuri, MD, Monica Bocchia, Alessandra Malato, MD PhD, Mauro Krampera, MD PhD, Giuseppe Lippi, MD PhD, Massimo Breccia, MD, Giuseppe Saglio, MD PhD, Antonella Gozzini, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 43–44.
https://doi.org/10.1182/blood-2020-139826
Published: 2020