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Olivier Legrand
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Journal Articles

Decitabine in older patients with AML: quality of life results of the EORTC-GIMEMA-GMDS-SG randomized phase 3 trial

Clinical Trials & Observations
Fabio Efficace, Michal Kicinski, Corneel Coens, Stefan Suciu, Walter J. F. M. van der Velden, Richard Noppeney, Sylvain Chantepie, Laimonas Griskevicius, Andreas Neubauer, Ernesta Audisio, Mario Luppi, Stephan Fuhrmann, Robin Foà, Martina Crysandt, Gianluca Gaidano, Radovan Vrhovac, Adriano Venditti, Eduardus F. M. Posthuma, Anna Candoni, Frédéric Baron, Olivier Legrand, Andrea Mengarelli, Paola Fazi, Marco Vignetti, Anne Giraut, Pierre W. Wijermans, Gerwin Huls, Michael Lübbert
Journal: Blood
Blood (2024) 144 (5): 541–551.
https://doi.org/10.1182/blood.2023023625
Published: 2024
Includes: Supplemental data
Journal Articles

10-Day Decitabine Versus Intensive Chemotherapy Followed By Transplantation in Fit AML Patients Aged ≥60 Years: Health-Related Quality of Life Outcomes of the Randomized Phase III Trial AML21 of the EORTC Leukemia Group, Gimema, Celg, and Gmds-SG

Fabio Efficace, Gerwin A. Huls, Michal Kicinski, Walter JFM Van Der Velden, Richard Noppeney, Sylvain Chantepie, Laimonas Griskevicius, Andreas Neubauer, Ernesta Audisio, Mario Luppi, Stephan Fuhrmann, Robin Foà, Martina Crysandt, Gianluca Gaidano, Radovan Vrhovac, Adriano Venditti, Eduardus F.M. Posthuma, Anna Candoni, Frederic Baron, Olivier Legrand, Andrea Mengarelli, Marco Vignetti, Anne Giraut, Corneel Coens, Stefan Suciu, P.W. Wijermans, Michael Luebbert
Journal: Blood
Blood (2022) 140 (Supplement 1): 1281–1283.
https://doi.org/10.1182/blood-2022-166544
Published: 2022
Journal Articles

Replacing the Anthracycline By Gemtuzumab Ozogamicin in Older Patients with De Novo Standard-Risk Acute Myeloid Leukemia Treated Intensively - Results of the Randomized ALFA1401-Mylofrance 4 Study

Juliette Lambert, Jérôme Lambert, Emilie Lemasle, Magalie Joris, Sylvain Chantepie, Cecile Pautas, Xavier Thomas, Jean Valere Malfuson, Lauris Gastaud, Denis Caillot, Emmanuelle Tavernier, Pascal Turlure, Diana Carp, Celine Berthon, Olivier Legrand, Ambroise Marçais, Iona Vaida, Sarah Barbieux, Philippe Rousselot, Claude Gardin, Christine Terré, Nicolas Duployez, Claude Preudhomme, Karine Celli-Lebras, Sylvie Castaigne, Herve Dombret
Journal: Blood
Blood (2021) 138 (Supplement 1): 31.
https://doi.org/10.1182/blood-2021-145152
Published: 2021
Journal Articles

Olutasidenib (FT-2102) in Combination with Azacitidine Induces Durable Complete Remissions in Patients with mIDH1 Acute Myeloid Leukemia

Jorge E. Cortes, Jordi Esteve, Ashish Bajel, Karen Yee, Thorsten Braun, Stephane De Botton, Pierre Peterlin, Christian Recher, Xavier Thomas, Justin Watts, Montserrat Arnan Sangerman, Antonio Curti, Carolyn Grove, Brian A. Jonas, Francesco Lanza, Olivier Legrand, Pau Montesinos, Prapti Patel, Thomas Prebet, Eunice S. Wang, Olga Polyanskaya, Julie Brevard, Jennifer Sweeney, Pierre Fenaux, Andrew H. Wei
Journal: Blood
Blood (2021) 138 (Supplement 1): 698.
https://doi.org/10.1182/blood-2021-144905
Published: 2021
Journal Articles

Molecular Characteristics of Response to Olutasidenib (FT-2102) in Patients with Relapsed/Refractory mIDH1 Acute Myeloid Leukemia

Stephane De Botton, Karen Yee, Christian Recher, Andrew H. Wei, Pau Montesinos, David Taussig, Arnaud Pigneux, Thorsten Braun, Antonio Curti, Jordi Esteve, Carolyn Grove, Brian A. Jonas, Asim Khwaja, Olivier Legrand, Pierre Peterlin, Montserrat Arnan Sangerman, William G. Blum, Daniela Cilloni, Devendra Hiwase, Joseph G. Jurcic, Jürgen Krauter, Xavier Thomas, Justin Watts, Jay Yang, Zihao Xin, Alex Sedkov, Sylvie Guichard, Jennifer Sweeney, Christophe Marzac, Jorge E. Cortes, Pierre Fenaux
Journal: Blood
Blood (2021) 138 (Supplement 1): 2351.
https://doi.org/10.1182/blood-2021-144912
Published: 2021
Journal Articles

CPX-351 Induces Deep Response and Suppress the Impact of Poor Prognosis Mutations ( TP53, ASXL1, RUNX1 and EVI1 ) Defined By ELN-2017 in t-AML and MRC AML: A Report from a Multicentric French Cohort

Edmond Chiche, Sarah Bertoli, MD PhD, Ramy Rahmé, MD, Jean Baptiste Micol, Florence Pasquier, MD PhD, Pierre Peterlin, Patrice Chevallier, MD, Xavier Thomas, MD PhD, Michael Loschi, MD PhD, Alexis Genthon, Olivier Legrand, MD PhD, Mohamad Mohty, MD PhD, Emmanuel Raffoux, MD, Patrick Auberger, PhD, Alexis Caulier, MD, Magalie Joris, MD, Caroline Bonmati, Gabrielle Roth Guepin, Mathieu Sauvezie, Caroline Lejeune, Arnaud Pigneux, Christian Recher, MD PhD, Lionel Ades, MD PhD, Thomas Cluzeau, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1355.
https://doi.org/10.1182/blood-2019-125623
Published: 2019
Journal Articles

Retinoic acid and arsenic trioxide trigger degradation of mutated NPM1, resulting in apoptosis of AML cells

Clinical Trials & Observations
Hiba El Hajj, Zeina Dassouki, Caroline Berthier, Emmanuel Raffoux, Lionel Ades, Olivier Legrand, Rita Hleihel, Umut Sahin, Nadim Tawil, Ala Salameh, Kazem Zibara, Nadine Darwiche, Mohamad Mohty, Hervé Dombret, Pierre Fenaux, Hugues de Thé, Ali Bazarbachi
Journal: Blood
Blood (2015) 125 (22): 3447–3454.
https://doi.org/10.1182/blood-2014-11-612416
Published: 2015
Includes: Supplemental data
Journal Articles

Results of the AFR07 Prospective Study in De Novo Philadelphia Positive ALL Patients Aged over 55 Years: Efficacy and Safety of a Glivec® Based Induction Followed by Maintenance Therapy with Glivec® and Pegasys®.

Philippe Rousselot, Christian Recher, Agnès Buzyn, Francis Witz, Norbert Vey, Martine Escoffre-Barbe, Olivier Legrand, Pascal Turlure, Françoise Huguet, Thibaut Leguay, Jacques Delaunay, Bruno Audhuy, Cécile Fohrer, Sébastien Maury, Sylvie Castaigne, Eric Vicaux, Hervé Dombret, Jean Michel Cayuela
Journal: Blood
Blood (2007) 110 (11): 2816.
https://doi.org/10.1182/blood.V110.11.2816.2816
Published: 2007
Journal Articles

Assessment of PML-RARa Real-Time Quantitative PCR for Definition of Molecular Relapse in APL Patients (Results of the APL Study Group).

Bruno Cassinat, Stephane De Botton, Lionel Ades, Emmanuel Raffoux, Martine Escoffre-Barbe, Andre Baruchel, Jean-Michel Miclea, Oumedaly Reman, Martine Gardembas, Philippe Brault, Noel Milpied, Olivier Legrand, Herve Dombret, Pierre Fenaux, Christine Chomienne
Journal: Blood
Blood (2005) 106 (11): 672.
https://doi.org/10.1182/blood.V106.11.672.672
Published: 2005
Journal Articles

Fractionated Doses Mylotarg in First Relapsed AML Patients Is Effective and Safe: Results of a Prospective French Alfa Group Study.

Anne Laure Taksin, Emmanuel Raffoux, Thierry de Revel, Xavier Thomas, Nathalie Contentin, Reda Bouabdallah, Cecile Pautas, Dominique Bordessoulle, Olivier Legrand, Herve Dombret, Fadela Pousset, Sylvie Chevret, Sylvie Castaigne
Journal: Blood
Blood (2005) 106 (11): 1850.
https://doi.org/10.1182/blood.V106.11.1850.1850
Published: 2005