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Hiba El Hajj
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Journal Articles

Arsenic Trioxide and Interferon-Alpha Eradicate Adult T Cell Leukemia Initiating Cells through PML/p53 Senescence and Activation of Innate Immunity

Hiba El Hajj, Dr, Rita Hleihel, Zaatari Ghazi, Julie Bruneau, Hideki Hasegawa, William Hall, Olivier Hermine, MD PhD, Hugues de The, MD PhD, Ali Bazarbachi, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1233.
https://doi.org/10.1182/blood.V130.Suppl_1.1233.1233
Published: 2017
Journal Articles

Arsenic Trioxide and Lenalidomide: A Promising Combination Therapy for Primary Effusion Lymphoma

Rita Hleihel, Nadim Tawil, Martin Karam, Raghida Abou Merhi, Ali Bazarbachi, MD PhD, Hiba El Hajj, Dr
Journal: Blood
Blood (2017) 130 (Supplement 1): 2817.
https://doi.org/10.1182/blood.V130.Suppl_1.2817.2817
Published: 2017
Journal Articles

Retinoic acid and arsenic trioxide trigger degradation of mutated NPM1, resulting in apoptosis of AML cells

Clinical Trials & Observations
Hiba El Hajj, Zeina Dassouki, Caroline Berthier, Emmanuel Raffoux, Lionel Ades, Olivier Legrand, Rita Hleihel, Umut Sahin, Nadim Tawil, Ala Salameh, Kazem Zibara, Nadine Darwiche, Mohamad Mohty, Hervé Dombret, Pierre Fenaux, Hugues de Thé, Ali Bazarbachi
Journal: Blood
Blood (2015) 125 (22): 3447–3454.
https://doi.org/10.1182/blood-2014-11-612416
Published: 2015
Includes: Supplemental data
Journal Articles

ATL response to arsenic/interferon therapy is triggered by SUMO/PML/RNF4-dependent Tax degradation

Zeina Dassouki, Umut Sahin, Hiba El Hajj, Florence Jollivet, Youmna Kfoury, Valérie Lallemand-Breitenbach, Olivier Hermine, Hugues de Thé, Ali Bazarbachi
Journal: Blood
Blood (2015) 125 (3): 474–482.
https://doi.org/10.1182/blood-2014-04-572750
Published: 2015
Includes: Supplemental data
Journal Articles

Preclinical efficacy of the synthetic retinoid ST1926 for treating adult T-cell leukemia/lymphoma

Hiba El Hajj, Bariaa Khalil, Botheina Ghandour, Rihab Nasr, Sharif Shahine, Akram Ghantous, Rana Abdel-Samad, Ansam Sinjab, Hideki Hasegawa, Mark Jabbour, William W. Hall, Ghazi Zaatari, Ghassan Dbaibo, Claudio Pisano, Ali Bazarbachi, Nadine Darwiche
Journal: Blood
Blood (2014) 124 (13): 2072–2080.
https://doi.org/10.1182/blood-2014-03-560060
Published: 2014
Includes: Supplemental data
Journal Articles

The Combination Of Arsenic, Interferon-Alpha, and Zidovudine Restores An “Immunocompetent-like” Micro-Environment In Patients With Adult T-Cell Leukemia/Lymphoma

Ghada Kchour, S. A. Rahim Rezaee, Reza Farid, Akram Ghantous, Houshang Rafatpana, Mahdi Tarhini, Mohamad-Mehdi Kooshyar, Hiba El Hajj, PhD, Fadwa Berry, Roudaina Nasser, Abbas Shirdel, Zeina Dassouki, Mohamad Ezzedine, Hossein Rahimi, Ardeshir Ghavamzadeh, Hugues de Thé, MD, PhD, Olivier Hermine, MD, PhD, Mahmoud Mahmoudi, Ali Bazarbachi, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 5100.
https://doi.org/10.1182/blood.V122.21.5100.5100
Published: 2013
Journal Articles

Combination Of Arsenic and Interferon-a Inhibits Expression Of KSHV Latent Transcripts and Synergistically Improves Survival Of Mice With Primary Effusion Lymphomas

Hiba El Hajj, PhD, Jihane Ali, Akram Ghantous, Dana Hodroj, Ahmad Daher, Ahmad Daher, Kazem Zibara, Chloé Journo, Zaher K. Otrock, MD, Ghazi Zaatari, MD, Renaud Mahieux, PhD, Marwan El Sabban, Raghida Abou Merhi, Ali Bazarbachi, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 5154.
https://doi.org/10.1182/blood.V122.21.5154.5154
Published: 2013
Journal Articles

Tax ubiquitylation and SUMOylation control the dynamic shuttling of Tax and NEMO between Ubc9 nuclear bodies and the centrosome

Youmna Kfoury, Niclas Setterblad, Marwan El-Sabban, Alessia Zamborlini, Zeina Dassouki, Hiba El Hajj, Olivier Hermine, Claudine Pique, Hugues de Thé, Ali Saïb, Ali Bazarbachi
Journal: Blood
Blood (2011) 117 (1): 190–199.
https://doi.org/10.1182/blood-2010-05-285742
Published: 2011
Includes: Supplemental data
Journal Articles

The Combination of Arsenic Trioxide and Interferon-Alpha Eradicates Leukemia Initiating Cells in TAX-Driven Murine Adult T Cell Leukemia/Lymphoma.

Ali Bazarbachi, MD, PhD, Hiba El Hajj, Marwan El-Sabban, Hideki Hasegawa, Ghazi Zaatari, Shahrazad Saab, Anne Janin, Rami Mahfouz, Rihab Nasr, Youmna Kfoury, Christophe Nicot, Olivier Hermine, William Hall, Hugues de The, MD, PhD
Journal: Blood
Blood (2009) 114 (22): 2714.
https://doi.org/10.1182/blood.V114.22.2714.2714
Published: 2009
Journal Articles

Phase 2 study of the efficacy and safety of the combination of arsenic trioxide, interferon alpha, and zidovudine in newly diagnosed chronic adult T-cell leukemia/lymphoma (ATL)

Clinical Trials & Observations
Ghada Kchour, Mahdi Tarhini, Mohamad-Mehdi Kooshyar, Hiba El Hajj, Eric Wattel, Mahmoud Mahmoudi, Hassan Hatoum, Hossein Rahimi, Masoud Maleki, Houshang Rafatpanah, S. A. Rahim Rezaee, Mojtaba Tabatabaei Yazdi, Abbas Shirdel, Hugues de Thé, Olivier Hermine, Reza Farid, Ali Bazarbachi
Journal: Blood
Blood (2009) 113 (26): 6528–6532.
https://doi.org/10.1182/blood-2009-03-211821
Published: 2009
Journal Articles

EAPB0203, a member of the imidazoquinoxaline family, inhibits growth and induces caspase-dependent apoptosis in T-cell lymphomas and HTLV-I–associated adult T-cell leukemia/lymphoma

Georges Moarbess, Hiba El-Hajj, Youmna Kfoury, Marwan E. El-Sabban, Yves Lepelletier, Olivier Hermine, Carine Deleuze-Masquéfa, Pierre-Antoine Bonnet, Ali Bazarbachi
Journal: Blood
Blood (2008) 111 (7): 3770–3777.
https://doi.org/10.1182/blood-2007-11-121913
Published: 2008
Journal Articles

Molecular Mechanisms of NF-kappaB Activation by the HTLV-I Oncoprotein Tax: Role of Post Translational Protein Modification.

Youmna Kfoury, Rihab Nasr, PhD, Arnaud Favre-Bonvin, PhD, Marwan El-Sabban, PhD, Noemie Renault, Marie-Louise Giron, PhD, Hiba El Hajj, PhD, Estelle Chiari, PhD, Abdul Ghani Mikati, Olivier Hermine, MD, PhD, Ali Saib, PhD, Hugues de Thé, MD, PhD, Claudine Pique, PhD, Ali Bazarbachi, MD, PhD
Journal: Blood
Blood (2007) 110 (11): 4159.
https://doi.org/10.1182/blood.V110.11.4159.4159
Published: 2007
Journal Articles

Targeted Therapy with Arsenic Trioxide and Interferon alpha Eradicates Leukemic Cells in SCID Mice Model of Adult T-Cell Leukemia/Lymphoma.

Hiba El Hajj, PhD, Hideki Hasegawa, PhD, Marwan El-Sabban, PhD, Ghazi Zaatari, MD, Shehrazad Saab, MD, Rami Mahfouz, MD, Rihab Nasr, PhD, Youmna Kfoury, Olivier Hermine, MD, PhD, Hugues de Thé, MD, PhD, William Hall, Ali Bazarbachi, MD, PhD
Journal: Blood
Blood (2007) 110 (11): 1379.
https://doi.org/10.1182/blood.V110.11.1379.1379
Published: 2007