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Journal Articles

Actionable Findings from an Unbiased Drug Screen for Novel Single Agent and Combination Therapies Against AML with Mecom Re-Arrangement

Christine Birdwell, Warren C. Fiskus, Christopher Peter Mill, Tapan M. Kadia, Naval Daver, Courtney D. DiNardo, Koji Sasaki, John Davis, Kaberi Das, Hanxi Hou, Michele Ceribelli, Kapil N. Bhalla

Blood (2023) 142 (Supplement 1): 1419.

https://doi.org/10.1182/blood-2023-188371

Published: 2023

Journal Articles

Preclinical Studies Demonstrating Efficacy of Tasquinimod in Models of Advanced Myeloproliferative Neoplasm (MPN) in Blastic Phase

Warren C. Fiskus, Lucia Masarova, Christopher Peter Mill, Christine Birdwell, Kaberi Das, John Davis, Hanxi Hou, Noor Alhamadani, Kevin Philip, Alicia Matthews, Taghi Manshouri, Tapan M. Kadia, Courtney D. DiNardo, Prithviraj Bose, Naveen Pemmaraju, Sanam Loghavi, Marie Törngren, Kapil N. Bhalla

Blood (2023) 142 (Supplement 1): 741.

https://doi.org/10.1182/blood-2023-185031

Published: 2023

Journal Articles

Novel Agents with Efficacy Against Cellular Models of Familial Platelet Disorder with Myeloid Malignancy (FPD-MM) Associated with Germline Mutant RUNX1

Christopher Peter Mill, Warren C. Fiskus, Courtney D. DiNardo, Patrick K Reville, John Davis, Christine Birdwell, Kaberi Das, Hanxi Hou, Koichi Takahashi, Sanam Loghavi, Joseph D. Khoury, Kapil N. Bhalla

Blood (2023) 142 (Supplement 1): 2765.

https://doi.org/10.1182/blood-2023-190655

Published: 2023

Journal Articles

Pre-Clinical Efficacy of CDK7 Inhibitor-Based Combinations in Cellular Models of Advanced Myeloproliferative Neoplasms (MPN) Transformed to AML

Warren C. Fiskus, Prithviraj Bose, Lucia Masarova, Christopher Peter Mill, Christine Birdwell, John Davis, Kaberi Das, Hanxi Hou, Taghi Manshouri, Kevin Philip, Noor Alhamadani, Alicia Matthews, Sanam Loghavi, Kapil N. Bhalla

Blood (2023) 142 (Supplement 1): 1783.

https://doi.org/10.1182/blood-2023-185089

Published: 2023

Journal Articles

Notable Efficacy of Co-Treatment with FHD-286, a Dual BRG1/BRM ATP-Ase Inhibitor, and Menin or BET Inhibitor, Decitabine or Venetoclax Against AML with MLL-r or Mutant NPM1

Warren C. Fiskus, Jessica Piel, Murphy Hentemann, Christopher Peter Mill, Christine Birdwell, Kaberi Das, John Davis, Hanxi Hou, Noor Alhamadani, Kevin Philip, Alicia Matthews, Tapan M. Kadia, Naval Daver, Sanam Loghavi, Branko Cuglievan, Courtney D. DiNardo, Kapil N. Bhalla

Blood (2023) 142 (Supplement 1): 4160.

https://doi.org/10.1182/blood-2023-182575

Published: 2023

Journal Articles

A Radiolabeled PF-4 Staph-a Binding Assay Proposed As a Solitary Method for Confirming Heparin Induced Thrombocytopenia

Kenneth A. Schwartz, MD, John Davis, B.S., Hemasri Tokala, MD

Blood (2014) 124 (21): 5011.

https://doi.org/10.1182/blood.V124.21.5011.5011

Published: 2014

Journal Articles

A Light Aggregometry Based Method To Measure The Percentage Of An Individual’s Platelets That Are Inhibited By Aspirin

Kenneth A. Schwartz, MD, John Davis, B.S., Jordan Schaefer, MD

Blood (2013) 122 (21): 2390.

https://doi.org/10.1182/blood.V122.21.2390.2390

Published: 2013

Journal Articles

Pharmacodynamics of Platelet Inhibition with Aspirin: Feasibility for Detection of Suboptimal Platelet Inhibition

Jordan Schaefer, MD, John Davis, B.S., Kenneth A. Schwartz, MD

Blood (2012) 120 (21): 4361.

https://doi.org/10.1182/blood.V120.21.4361.4361

Published: 2012

Journal Articles

Graft invariant natural killer T-cell dose predicts risk of acute graft-versus-host disease in allogeneic hematopoietic stem cell transplantation

Aristeidis Chaidos, Scott Patterson, Richard Szydlo, Mohammed Suhail Chaudhry, Francesco Dazzi, Edward Kanfer, Donald McDonald, David Marin, Dragana Milojkovic, Jiri Pavlu, John Davis, Amin Rahemtulla, Katy Rezvani, John Goldman, Irene Roberts, Jane Apperley, Anastasios Karadimitris

Blood (2012) 119 (21): 5030–5036.

https://doi.org/10.1182/blood-2011-11-389304

Published: 2012

Includes: Supplemental data

Journal Articles

Histopathologic Study of Livers From Chronic Iron Loaded C282Y Mice: Model of Hereditary Hemochromatosis?

Kenneth A. Schwartz, MD, John Davis, B.S., Michael A. Scott, DVM, PhD, Lana Kaiser, MD, DVM

Blood (2011) 118 (21): 5288.

https://doi.org/10.1182/blood.V118.21.5288.5288

Published: 2011

Journal Articles

Cryopreserved Allogeneic Peripheral Blood Stem Cells Result in Outcome Equivalent to Those of Fresh Infusions Enabling Rational Scheduling of Donations,

Bhuvan Kishore, John Davis, Katayoun Rezvani, MD, PhD, David Marin, Richard M Szydlo, Loaiza Sandra, Giles Chrissy, Aristeidis Chaidos, Edward J Kanfer, Anastasios Karadimitris, Donald H MacDonald, Dragana Milojkovic, MD, Amin Rahemtulla, John M Goldman, Jane F Apperley, MBChB, MD, FRCP, FRCPath, Jiri Pavlu

Blood (2011) 118 (21): 4052.

https://doi.org/10.1182/blood.V118.21.4052.4052

Published: 2011

Journal Articles

Amount of Platelet Inhibition Produced When Initiating Aspirin Therapy: Comparison of Two Doses 81 Vs. 325

Kenneth A. Schwartz, MD, Simona Chivu, MD, John Davis, B.S.

Blood (2011) 118 (21): 1250.

https://doi.org/10.1182/blood.V118.21.1250.1250

Published: 2011

Journal Articles

Variations In Efficiency of Donor Searches Between International Unrelated Blood and Marrow Donor Registries.

Roisin Dunwoody, BSc, Richard Szydlo, PhD, Linda Casey, John Davis, PhD, Susan LLoyd, Ian H Gabriel, MD, Katayoun Rezvani, MD, PhD, Jane F Apperley, MD

Blood (2010) 116 (21): 1524.

https://doi.org/10.1182/blood.V116.21.1524.1524

Published: 2010

Journal Articles

High Frequency and Cell Dose of Invariant NKT Cells In the Graft Are Associated with Lack of Clinically Significant Acute Gvhd In T Cell-Replete Sibling Allografts

Aristeidis Chaidos, MD, PhD, Richard M. Szydlo, Edward J. Kanfer, Francesco Dazzi, Donald H. MacDonald, David Marin, MD, FRCP, Dragana Milojkovic, Jiri Pavlu, John Davis, PhD, Katayoun Rezvani, MD, PhD, Amin Rahemtulla, MBBS, PhD, FRCP, Irene Roberts, MD, Jane F. Apperley, Anastasios Karadimitris

Blood (2010) 116 (21): 2539.

https://doi.org/10.1182/blood.V116.21.2539.2539

Published: 2010

Journal Articles

Interaction between KIR3DS1 and HLA-Bw4 predicts for progression-free survival after autologous stem cell transplantation in patients with multiple myeloma

Ian H. Gabriel, Ruhena Sergeant, Richard Szydlo, Jane F. Apperley, Hugues deLavallade, Abdullah Alsuliman, Ahmad Khoder, David Marin, Edward Kanfer, Nichola Cooper, John Davis, Donald MacDonald, Marco Bua, Letizia Foroni, Chrissy Giles, Dragana Milojkovic, Amin Rahemtulla, Katayoun Rezvani

Blood (2010) 116 (12): 2033–2039.

https://doi.org/10.1182/blood-2010-03-273706

Published: 2010

Journal Articles

Presence of the Killer Immunoglobulin-Like Gene KIR3DS1 Is Associated with Poor Progression Free and Overall Survival Following Autologous Stem Cell Transplantation in Patients with Myeloma.

Ian H Gabriel, Dr, Ruhena Sargent, Dr, Hugues de Lavallade, Richard Szydlo, Jane Apperley, Ahmad Khoder, Dr, Abdullah Alsuliman, David Marin, Letizia Foroni, John Davis, Chrissy Giles, Edward Kanfer, MD, Amin Rahemtulla, MBBS, PhD, FRCP, Katayoun Rezvani, MD, PhD

Blood (2009) 114 (22): 2840.

https://doi.org/10.1182/blood.V114.22.2840.2840

Published: 2009

Journal Articles

Low Dose Alemtuzumab Achieves Long-Term Engraftment with Low Level Mixed Chimerism in Related Haemopoietic Stem Cell Transplantation for Haemoglobinopathies

Josu de la Fuente, Farah O’Boyle, Natalie Killeen, Allison Tso, Helen New, Ayad Atra, Inderjeet Dokal, Tom Vulliamy, John Davis, Letizia Foroni, Richard M. Szydlo, Irene Roberts

Blood (2008) 112 (11): 3304.

https://doi.org/10.1182/blood.V112.11.3304.3304

Published: 2008

Journal Articles

Iron Sufficient to Cause Hepatic Fibrosis and Ascites Does Not Cause Cardiac Arrhythmias in the Gerbil

Lana Kaiser, MD, DVM, John Davis, BS, Jon Patterson, DVM, Abby Johnson, George Bohart, DVM, Kenneth A. Schwartz, MD

Blood (2008) 112 (11): 3834.

https://doi.org/10.1182/blood.V112.11.3834.3834

Published: 2008

Journal Articles

Full Donor Engraftment without Chronic GvHD Following HLA-Matched Sibling Donor Haemopoietic Stem Cell Transplantation for Diamond Blackfan Anaemia

Jayanthi Alamelu, Farah O’Boyle, Natalie Killeen, Helen New, Ayad Atra, Inderjeet Dokal, John Davis, Letizia Foroni, Richard M. Szydlo, Irene Roberts, Josu de la Fuente

Blood (2008) 112 (11): 4394.

https://doi.org/10.1182/blood.V112.11.4394.4394

Published: 2008

Journal Articles

Iron Does Not Cause Arrhythmias in the Guinea Pig Model of Transfusional Iron Overload.

Lana Kaiser, MD, DVM, John Davis, BS, Jon Patterson, DVM, N. Bari Olivier, DVM, George Bohart, DVM, Kenneth Schwartz, MD

Blood (2006) 108 (11): 3724.

https://doi.org/10.1182/blood.V108.11.3724.3724

Published: 2006

NARROW

Actionable Findings from an Unbiased Drug Screen for Novel Single Agent and Combination Therapies Against AML with Mecom Re-Arrangement

Preclinical Studies Demonstrating Efficacy of Tasquinimod in Models of Advanced Myeloproliferative Neoplasm (MPN) in Blastic Phase

Novel Agents with Efficacy Against Cellular Models of Familial Platelet Disorder with Myeloid Malignancy (FPD-MM) Associated with Germline Mutant RUNX1

Pre-Clinical Efficacy of CDK7 Inhibitor-Based Combinations in Cellular Models of Advanced Myeloproliferative Neoplasms (MPN) Transformed to AML

Notable Efficacy of Co-Treatment with FHD-286, a Dual BRG1/BRM ATP-Ase Inhibitor, and Menin or BET Inhibitor, Decitabine or Venetoclax Against AML with MLL-r or Mutant NPM1

A Radiolabeled PF-4 Staph-a Binding Assay Proposed As a Solitary Method for Confirming Heparin Induced Thrombocytopenia

A Light Aggregometry Based Method To Measure The Percentage Of An Individual’s Platelets That Are Inhibited By Aspirin

Pharmacodynamics of Platelet Inhibition with Aspirin: Feasibility for Detection of Suboptimal Platelet Inhibition

Graft invariant natural killer T-cell dose predicts risk of acute graft-versus-host disease in allogeneic hematopoietic stem cell transplantation

Histopathologic Study of Livers From Chronic Iron Loaded C282Y Mice: Model of Hereditary Hemochromatosis?

Cryopreserved Allogeneic Peripheral Blood Stem Cells Result in Outcome Equivalent to Those of Fresh Infusions Enabling Rational Scheduling of Donations,

Amount of Platelet Inhibition Produced When Initiating Aspirin Therapy: Comparison of Two Doses 81 Vs. 325

Variations In Efficiency of Donor Searches Between International Unrelated Blood and Marrow Donor Registries.

High Frequency and Cell Dose of Invariant NKT Cells In the Graft Are Associated with Lack of Clinically Significant Acute Gvhd In T Cell-Replete Sibling Allografts

Interaction between KIR3DS1 and HLA-Bw4 predicts for progression-free survival after autologous stem cell transplantation in patients with multiple myeloma

Presence of the Killer Immunoglobulin-Like Gene KIR3DS1 Is Associated with Poor Progression Free and Overall Survival Following Autologous Stem Cell Transplantation in Patients with Myeloma.

Low Dose Alemtuzumab Achieves Long-Term Engraftment with Low Level Mixed Chimerism in Related Haemopoietic Stem Cell Transplantation for Haemoglobinopathies

Iron Sufficient to Cause Hepatic Fibrosis and Ascites Does Not Cause Cardiac Arrhythmias in the Gerbil

Full Donor Engraftment without Chronic GvHD Following HLA-Matched Sibling Donor Haemopoietic Stem Cell Transplantation for Diamond Blackfan Anaemia

Iron Does Not Cause Arrhythmias in the Guinea Pig Model of Transfusional Iron Overload.

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American Society of Hematology

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American Society of Hematology

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