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Alexander Tzankov
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Journal Articles

Genetic and phenotypic attributes of splenic marginal zone lymphoma

Ferdinando Bonfiglio, Alessio Bruscaggin, Francesca Guidetti, Lodovico Terzi di Bergamo, Martin Faderl, Valeria Spina, Adalgisa Condoluci, Luisella Bonomini, Gabriela Forestieri, Ricardo Koch, Deborah Piffaretti, Katia Pini, Maria Cristina Pirosa, Micol Giulia Cittone, Alberto Arribas, Marco Lucioni, Guido Ghilardi, Wei Wu, Luca Arcaini, Maria Joao Baptista, Gabriela Bastidas, Silvia Bea, Renzo Boldorini, Alessandro Broccoli, Marco Matteo Buehler, Vincenzo Canzonieri, Luciano Cascione, Luca Ceriani, Sergio Cogliatti, Paolo Corradini, Enrico Derenzini, Liliana Devizzi, Sascha Dietrich, Angela Rita Elia, Fabio Facchetti, Gianluca Gaidano, Juan Fernando Garcia, Bernhard Gerber, Paolo Ghia, Maria Gomes da Silva, Giuseppe Gritti, Anna Guidetti, Felicitas Hitz, Giorgio Inghirami, Marco Ladetto, Armando Lopez-Guillermo, Elisa Lucchini, Antonino Maiorana, Roberto Marasca, Estella Matutes, Veronique Meignin, Michele Merli, Alden Moccia, Manuela Mollejo, Carlos Montalban, Urban Novak, David Graham Oscier, Francesco Passamonti, Francesco Piazza, Stefano Pizzolitto, Alessandro Rambaldi, Elena Sabattini, Gilles Salles, Elisa Santambrogio, Lydia Scarfò, Anastasios Stathis, Georg Stüssi, Julia T. Geyer, Gustavo Tapia, Corrado Tarella, Catherine Thieblemont, Thomas Tousseyn, Alessandra Tucci, Giorgio Vanini, Carlo Visco, Umberto Vitolo, Renata Walewska, Francesco Zaja, Thorsten Zenz, Pier Luigi Zinzani, Hossein Khiabanian, Arianna Calcinotto, Francesco Bertoni, Govind Bhagat, Elias Campo, Laurence De Leval, Stefan Dirnhofer, Stefano A. Pileri, Miguel A. Piris, Alexandra Traverse-Glehen, Alexander Tzankov, Marco Paulli, Maurilio Ponzoni, Luca Mazzucchelli, Franco Cavalli, Emanuele Zucca, Davide Rossi
Journal: Blood
Blood (2022) 139 (5): 732–747.
https://doi.org/10.1182/blood.2021012386
Published: 2022
Includes: Supplemental data
Journal Articles

Akt Activation Confers an Inferior Survival in Patients with Activated B-Cell Subtype of Diffuse Large B-Cell Lymphoma: A Report from the International DLBCL Rituximab-CHOP Consortium Program

Qi Shen, Zijun Yidan Xu-Monette, PhD, Ganiraju Manyam, Carlo Visco, Alexander Tzankov, MD PhD, Xin Cao, Lijuan Deng, Santiago Montes-Moreno, MD PhD, Karen Dybkær, April Chiu, MD, Attilio Orazi, MD, Youli Zu, MD PhD, Govind Bhagat, MD, Kristy L. Richards, MDPhD, Eric D. Hsi, MD, William Choi, Joannes H.J.M. Van Krieken, PhDMD, Jooryung Huh, Maurilio Ponzoni, MD, Andres J.M. Ferreri, MD PhD, John P. Farnen, MD, Michael B. Møller, MD DMSc, Jane N. Winter, MD, Miguel Angel A. Piris, MD PhD, L. Jeffrey Medeiros, MD, Ken H. Young, MD PhD
Journal: Blood
Blood (2014) 124 (21): 143.
https://doi.org/10.1182/blood.V124.21.143.143
Published: 2014
Journal Articles

Conditional Expression of a Leukemogenic Fusion Oncogene in Murine Hematopoietic Stem Cells Results in Highly Invasive AML with Origin-Related Genetic Signatures of Prognostic Significance for the Human Disease

Vaia Stavropoulou, PhD, Susanne Kaspar, Laurent Brault, PhD, Sabine Juge, Alexander Tzankov, MD PhD, Mathijs A. Sanders, MSc, Michael Kyba, PhD, Peter J.M. Valk, PhD, Antoine H.F.M. Peters, PhD, Juerg Schwaller, MD
Journal: Blood
Blood (2014) 124 (21): 779.
https://doi.org/10.1182/blood.V124.21.779.779
Published: 2014
Journal Articles

A Novel Conditional Mouse Model For MLL-ENL Induced Acute Leukemia

Vaia Stavropoulou, PhD, Sabine Juge, Alexander Tzankov, MD, PhD, Michael Kyba, PhD, Antoine H.F.M. Peters, PhD, Juerg Schwaller, MD
Journal: Blood
Blood (2013) 122 (21): 1277.
https://doi.org/10.1182/blood.V122.21.1277.1277
Published: 2013
Journal Articles

STAT3 Expression and Clinical Implications In De Novo Diffuse Large B-Cell Lymphoma: A Report From The International DLBCL Rituximab-CHOP Consortium Program

Chi Young Ok, MD, Zijun Y. Xu-Monette, PhD, Alexander Tzankov, MD, PhD, Carlo Visco, MD, Santiago M. Montes, MD, PhD, Karen Dybkaer, PhD, April Chiu, MD, Attilio Orazi, MD, Youli Zu, MD, PhD, Govind Bhagat, MD, PhD, Kristy L. Richards, MD PhD, Eric D. Hsi, MD, William W. L. Choi, MD, PhD, Joannes H.J.M. Van Krieken, PhD, MD, Qin Huang, MD, PhD, Jooryung Huh, MD, Weiyun Z. Ai, MD, PhD, Maurilio Ponzoni, MD, AndrÉs J.M. Ferreri,, MD, PhD, John P. Farnen, MD, FACP, Michael B. Moller, MD, PhD, Jane N. Winter, MD, Miguel A. Piris, MD, PhD, L. Jeffrey Medeiros, MD, Ken H. Young, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 365.
https://doi.org/10.1182/blood.V122.21.365.365
Published: 2013
Journal Articles

MYC Mutation Profiling In 708 De Novo Diffuse Large B-Cell Lymphoma Demonstrates That Genetic Abnormalities In The Coding Sequence and Untranslated Regions Have Different Prognostic and Clinical Significance: A Report From The International DLBCL Rituximab-CHOP Consortium Program

Zijun Y. Xu-Monette, PhD, Alexander Tzankov, MD, Yong Li, PhD, Carlo Visco, MD, Santiago Montes-Moreno, MD, PhD, Karen Dybkaer, PhD, April Chiu, MD, Attilio Orazi, MD, Youli Zu, MD, PhD, Govind Bhagat, MD, Kristy L. Richards, MD PhD, Eric D. Hsi, MD, William W. L. Choi, MD, PhD, Joannes H.J.M. Van Krieken, PhD, MD, Jooryung Huh, MD, Weiyun Z. Ai, MD, PhD, Maurilio Ponzoni, MD, Andres J.M. Ferreri, MD, PhD, John P. Farnen, MD, FACP, Michael B. Moller, MD, PhD, Jane N. Winter, MD, Miguel A. Piris, MD, PhD, L. Jeffrey Medeiros, MD, Ken H. Young, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 363.
https://doi.org/10.1182/blood.V122.21.363.363
Published: 2013
Journal Articles

Radiation Therapy Significantly Improves Survival Of Patients With Diffuse Large B-Cell Lymphoma Associated With MYC Translocation: A Report From The International DLBCL Rituximab-CHOP Consortium Program

Zijun Y. Xu-Monette, PhD, Bouthaina S. Dabaja, MD, Alexander Tzankov, MD, PhD, Carlo Visco, MD, Roberto N. Miranda, MD, Karen Dybkaer, PhD, April Chiu, MD, Attilio Orazi, MD, Youli Zu, MD, PhD, Govind Bhagat, MD, Kristy L. Richards, MD PhD, Eric D. Hsi, MD, Wai Lap Choi, MD, Joannes H.J.M. Van Krieken, PhD, MD, Jooryung Huh, MD, Weiyun Z. Ai, MD, PhD, Maurilio Ponzoni, MD, Andres Ferreri, MD, PhD, Michael B. Moller, MD, PhD, Xiaoying Zhao, MD, Ronald S. Go, MD, Jane N. Winter, MD, Miguel Angel A. Piris, MD, PhD, Timothy J. McDonnell, MD, PhD, Yong Li, PhD, L. Jeffrey Medeiros, MD, Ken H. Young, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 641.
https://doi.org/10.1182/blood.V122.21.641.641
Published: 2013
Journal Articles

Radiation Therapy Significantly Improves Survival Of Patients With Diffuse Large B-Cell Lymphoma Associated With MYC Translocation: A Report From The International DLBCL Rituximab-CHOP Consortium Program

Zijun Y. Xu-Monette, PhD, Bouthaina S. Dabaja, MD, Alexander Tzankov, MD, PhD, Carlo Visco, MD, Roberto N. Miranda, MD, Karen Dybkaer, PhD, April Chiu, MD, Attilio Orazi, MD, Youli Zu, MD, PhD, Govind Bhagat, MD, Kristy L. Richards, MD PhD, Eric D. Hsi, MD, Wai Lap Choi, MD, Joannes H.J.M. Van Krieken, PhD, MD, Jooryung Huh, MD, Weiyun Z. Ai, MD, PhD, Maurilio Ponzoni, MD, Andres Ferreri, MD, PhD, Michael B. Moller, MD, PhD, Xiaoying Zhao, MD, Ronald S. Go, MD, Jane N. Winter, MD, Miguel Angel A. Piris, MD, PhD, Timothy J. McDonnell, MD, PhD, Yong Li, PhD, L. Jeffrey Medeiros, MD, Ken H. Young, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 213.
https://doi.org/10.1182/blood.V122.21.213.213
Published: 2013
Journal Articles

MDM2 phenotypic and genotypic profiling, respective to TP53 genetic status, in diffuse large B-cell lymphoma patients treated with rituximab-CHOP immunochemotherapy: a report from the International DLBCL Rituximab-CHOP Consortium Program

Zijun Y. Xu-Monette, Michael B. Møller, Alexander Tzankov, Santiago Montes-Moreno, Wenwei Hu, Ganiraju C. Manyam, Louise Kristensen, Lei Fan, Carlo Visco, Karen Dybkær, April Chiu, Wayne Tam, Youli Zu, Govind Bhagat, Kristy L. Richards, Eric D. Hsi, William W. L. Choi, J. Han van Krieken, Qin Huang, Jooryung Huh, Weiyun Ai, Maurilio Ponzoni, Andrés J. M. Ferreri, Lin Wu, Xiaoying Zhao, Carlos E. Bueso-Ramos, Sa A. Wang, Ronald S. Go, Yong Li, Jane N. Winter, Miguel A. Piris, L. Jeffrey Medeiros, Ken H. Young
Journal: Blood
Blood (2013) 122 (15): 2630–2640.
https://doi.org/10.1182/blood-2012-12-473702
Published: 2013
Includes: Supplemental data
Journal Articles

IκB-ζ controls the constitutive NF-κB target gene network and survival of ABC DLBCL

Hendrik Nogai, Sören-Sebastian Wenzel, Stephan Hailfinger, Michael Grau, Eva Kaergel, Volkhard Seitz, Brigitte Wollert-Wulf, Matthias Pfeifer, Annette Wolf, Mareike Frick, Kerstin Dietze, Hannelore Madle, Alexander Tzankov, Michael Hummel, Bernd Dörken, Claus Scheidereit, Martin Janz, Peter Lenz, Margot Thome, Georg Lenz
Journal: Blood
Blood (2013) 122 (13): 2242–2250.
https://doi.org/10.1182/blood-2013-06-508028
Published: 2013
Includes: Supplemental data
Journal Articles

Single nucleotide variation in the TP53 3′ untranslated region in diffuse large B-cell lymphoma treated with rituximab-CHOP: a report from the International DLBCL Rituximab-CHOP Consortium Program

Yong Li, Michael W. Gordon, Zijun Y. Xu-Monette, Carlo Visco, Alexander Tzankov, Dehui Zou, Lugui Qiu, Santiago Montes-Moreno, Karen Dybkaer, Attilio Orazi, Youli Zu, Govind Bhagat, Kristy L. Richards, Eric D. Hsi, William W. L. Choi, J. Han van Krieken, Qin Huang, Weiyun Ai, Maurilio Ponzoni, Andrés J. M. Ferreri, Jane N. Winter, Ronald S. Go, Miguel A. Piris, Michael B. Møller, Lin Wu, Michael Wang, Kenneth S. Ramos, L. Jeffrey Medeiros, Ken H. Young
Journal: Blood
Blood (2013) 121 (22): 4529–4540.
https://doi.org/10.1182/blood-2012-12-471722
Published: 2013
Includes: Supplemental data
Journal Articles

MYC/BCL2 protein coexpression contributes to the inferior survival of activated B-cell subtype of diffuse large B-cell lymphoma and demonstrates high-risk gene expression signatures: a report from The International DLBCL Rituximab-CHOP Consortium Program

CME
Shimin Hu, Zijun Y. Xu-Monette, Alexander Tzankov, Tina Green, Lin Wu, Aarthi Balasubramanyam, Wei-min Liu, Carlo Visco, Yong Li, Roberto N. Miranda, Santiago Montes-Moreno, Karen Dybkaer, April Chiu, Attilio Orazi, Youli Zu, Govind Bhagat, Kristy L. Richards, Eric D. Hsi, William W. L. Choi, Xiaoying Zhao, J. Han van Krieken, Qin Huang, Jooryung Huh, Weiyun Ai, Maurilio Ponzoni, Andrés J. M. Ferreri, Fan Zhou, Graham W. Slack, Randy D. Gascoyne, Meifeng Tu, Daina Variakojis, Weina Chen, Ronald S. Go, Miguel A. Piris, Michael B. Møller, L. Jeffrey Medeiros, Ken H. Young
Journal: Blood
Blood (2013) 121 (20): 4021–4031.
https://doi.org/10.1182/blood-2012-10-460063
Published: 2013
Includes: Supplemental data
Journal Articles

CD30 expression defines a novel subgroup of diffuse large B-cell lymphoma with favorable prognosis and distinct gene expression signature: a report from the International DLBCL Rituximab-CHOP Consortium Program Study

Shimin Hu, Zijun Y. Xu-Monette, Aarthi Balasubramanyam, Ganiraju C. Manyam, Carlo Visco, Alexander Tzankov, Wei-min Liu, Roberto N. Miranda, Li Zhang, Santiago Montes-Moreno, Karen Dybkær, April Chiu, Attilio Orazi, Youli Zu, Govind Bhagat, Kristy L. Richards, Eric D. Hsi, William W. L. Choi, J. Han van Krieken, Qin Huang, Jooryung Huh, Weiyun Ai, Maurilio Ponzoni, Andrés J. M. Ferreri, Xiaoying Zhao, Jane N. Winter, Mingzhi Zhang, Ling Li, Michael B. Møller, Miguel A. Piris, Yong Li, Ronald S. Go, Lin Wu, L. Jeffrey Medeiros, Ken H. Young
Journal: Blood
Blood (2013) 121 (14): 2715–2724.
https://doi.org/10.1182/blood-2012-10-461848
Published: 2013
Includes: Supplemental data
Journal Articles

Cellular and Molecular Targets of MLL-AF9 in a Novel Conditional Mouse Model

Vaia Stavropoulou, PhD, Susanne Kaspar, Laurent Brault, PhD, Sabine Juge, Stefano Morettini, PhD, Alexander Tzankov, MD, Michael Kyba, PhD, Antoine H.F.M. Peters, PhD, Juerg Schwaller, MD
Journal: Blood
Blood (2012) 120 (21): 1280.
https://doi.org/10.1182/blood.V120.21.1280.1280
Published: 2012
Journal Articles

Prognostic Significance and Phenotypic Manifestations of MYC/BCL2 Protein Expression in Diffuse Large B-Cell Lymphoma (DLBCL) with Extranodal Organ Involvement: A Report of the International DLBCL Rituximab-CHOP Consortium Program Study

Anusha Madadi, MD, Meghana Raghavendra, MD, Shimin Hu, Zijun Y. Xu-Monette, PhD, Carlo Visco, MD, Alexander Tzankov, MD, Santiago Montes-Moreno, MD, Karen Dybkaer, April Chiu, MD, Attilio Orazi, MD, Youli Zu, MD, PhD, Govind Bhagat, MD, Cherie H. Dunphy, MD, Eric D. Hsi, MD, Frank X. Zhao, MD, PhD, William W. L. Choi, MD, Xiaoying Zhao, MD, Joannes H.J.M. Van Krieken, PhD, MD, Jooryung Huh, MD, Qin Huang, MD, PhD, Wei Ai, MD, Maurilio Ponzoni, Andrés J.M. Ferreri, MD, Fan Zhou, MD, PhD, Jane N. Winter, MD, Miguel Piris, MD, Michael B. Møller, MD, DMSc, L. Jeffrey Medeiros, MD, Ronald S. Go, MD, Ken H. Young, MD
Journal: Blood
Blood (2012) 120 (21): 544.
https://doi.org/10.1182/blood.V120.21.544.544
Published: 2012
Journal Articles

Mutational profile and prognostic significance of TP53 in diffuse large B-cell lymphoma patients treated with R-CHOP: report from an International DLBCL Rituximab-CHOP Consortium Program Study

Clinical Trials & Observations
Zijun Y. Xu-Monette, Lin Wu, Carlo Visco, Yu Chuan Tai, Alexander Tzankov, Wei-min Liu, Santiago Montes-Moreno, Karen Dybkær, April Chiu, Attilio Orazi, Youli Zu, Govind Bhagat, Kristy L. Richards, Eric D. Hsi, X. Frank Zhao, William W. L. Choi, Xiaoying Zhao, J. Han van Krieken, Qin Huang, Jooryung Huh, Weiyun Ai, Maurilio Ponzoni, Andrés J. M. Ferreri, Fan Zhou, Brad S. Kahl, Jane N. Winter, Wei Xu, Jianyong Li, Ronald S. Go, Yong Li, Miguel A. Piris, Michael B. Møller, Roberto N. Miranda, Lynne V. Abruzzo, L. Jeffrey Medeiros, Ken H. Young
Journal: Blood
Blood (2012) 120 (19): 3986–3996.
https://doi.org/10.1182/blood-2012-05-433334
Published: 2012
Includes: Supplemental data
Journal Articles

The t(14;18)(q32;q21) Characterizes a Subset of Patients with Diffuse Large-B Cell Lymphoma of Germinal Center Origin with Poor Outcome: Report From the International DLBCL Rituximab-CHOP Consortium Program Study

Carlo Visco, MD, Alexander Tzankov, MD, Zijun Y. Xu-Monette, PhD, Roberto N. Miranda, MD, Emanuele S. G. d'Amore, MD, Santiago Montes-Moreno, MD, Karen Dybkaer, PhD, April Chiu, MD, Wayne Tam, MD, PhD, Attilio Orazi, MD, Youli Zu, MD, PhD, Govind Bhagat, MD, Brad S. Kahl, MD, Jane N. Winter, MD, Huan-You Wang, MD, PhD, Cherie H. Dunphy, MD, Eric D. Hsi, MD, Frank X. Zhao, MD, PhD, Ronald S. Go, MD, William W. L. Choi, MD, Fan Zhou, MD, PhD, Magdalena Czader, MD, PhD, Xiaoying Zhao, MD, Joannes H.J.M. Van Krieken, PhD, MD, Qin Huang, MD, PhD, Weiyun Ai, MD, PhD, Joan E. Etzell, MD, Maurilio Ponzoni, MD, Andres J.M. Ferreri, MD, Miguel A. Piris, MD, Michael B. Møller, MD, PhD, Carlos E. Bueso-Ramos, MD, PhD, L. Jeffrey Medeiros, MD, Ken H. Young, MD
Journal: Blood
Blood (2011) 118 (21): 949.
https://doi.org/10.1182/blood.V118.21.949.949
Published: 2011
Journal Articles

Myc-mediated repression of microRNA-34a promotes high-grade transformation of B-cell lymphoma by dysregulation of FoxP1

Vanessa J. Craig, Sergio B. Cogliatti, Jochen Imig, Christoph Renner, Stefan Neuenschwander, Hubert Rehrauer, Ralph Schlapbach, Stephan Dirnhofer, Alexander Tzankov, Anne Müller
Journal: Blood
Blood (2011) 117 (23): 6227–6236.
https://doi.org/10.1182/blood-2010-10-312231
Published: 2011
Includes: Supplemental data
Journal Articles

Large Granular Lymphocyte Expansion Following Allogeneic Hematopoietic Stem Cell Transplantation Is Associated with the Presence of CMV Reactivation and Probably with Acute GvHD and Shows An Indolent Outcome.

Sabine Nann, MD, Alexander Tzankov, MD, Nathan Cantoni, MD, Jörg Halter, MD, Dominik Heim, MD, Dimitrios Tsakiris, MD, Caroline Arber, MD, Andreas Buser, MD, Alois Gratwohl, MD, Andre Tichelli, MD, Alicia Rovo, MD
Journal: Blood
Blood (2010) 116 (21): 3461.
https://doi.org/10.1182/blood.V116.21.3461.3461
Published: 2010
Journal Articles

Clinical Impact of TP53 Gene Mutations in Diffuse Large B-Cell Lymphoma (DLBCL): An International DLBCL Rituxan-CHOP Consortium Program Study.

Ken H. Young, MD, PhD, Nancy Patten, PhD, Sim Truong, PhD, Jens Eickhoff, PhD, Gabrielle L. Rocque, MD, Jeffrey T. Malik, MD, Yan Li, PhD, Kazunori Kanehira, MD, PhD, Matthew Twohig, MD, William M. Rehrauer, PhD, Michelle A. Waknitz, MS, Brad S. Kahl, MD, Michael B. Moller, MD, PhD, Alexander Tzankov, PhD, Santiago M. Moreno, MD, Miguel A. Piris, MD, Carlo Visco, MD, Karen Dybkaer, PhD, April Chiu, MD, Attilio Orazi, MD, Jeff C. Chang, MD, PhD, Govind Bhagat, MD, Jane N. Winter, MD, Huan-You Wang, MD, PhD, Cherie Dunphy, MD, Stacey O'Neill, MD, PhD, Eric D. Hsi, MD, Xianfeng Zhao, MD, PhD, Kristin Hunt, MD, Weina Chen, MD, PhD, Ronald S. Go, MD, William W.L. Choi, MD, Fan Zhou, MD, PhD, Magdalena Czader, MD, PhD, Yong Li, PhD, Suzanne Selvaggi, MD, James S. Malter, MD, Lin Wu, PhD
Journal: Blood
Blood (2009) 114 (22): 967.
https://doi.org/10.1182/blood.V114.22.967.967
Published: 2009