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Hendrik Nogai
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Journal Articles

Safety and Efficacy Results from CLI120-001 a Phase 1 Study in RR-AML and HR-MDS: Update from Higher Dose Levels

Ewa Lech Marańda, Elżbieta Patkowska, Natalia Jakacka, Camille N. Abboud, Howard A. Burris, Scott R. Solomon, Noemi Angelosanto, Tomasz Rzymski, Peter Littlewood, Kamil Kuś, Agnieszka Sroka-Porada, Renata Dudziak, Hendrik Nogai, Axel Glasmacher, Terrence Bradley, Gautam Borthakur, Elie Mouhayar, Paweł Steckiewicz, Sylwia Kościółek- Zgódka, Agata Szymańska, Jan Maciej Zaucha
Journal: Blood
Blood (2023) 142 (Supplement 1): 2913.
https://doi.org/10.1182/blood-2023-186620
Published: 2023
Journal Articles

Preclinical and Clinical Evidence for Erythroid-Stimulating Activity of RVU120 CDK8/19 Inhibitor in AML and MDS

Noemi Angelosanto, Ewa Lech Marańda, Jan Maciej Zaucha, Camille N. Abboud, Agnieszka Sroka-Porada, Wiktoria Ogrodzińska, Magdalena Kozakowska, Urszula Głowniak-Kwitek, Karolina Bukowska-Strakova, Tomasz Rzymski, Milena Mazan, Urszula Pakulska, Kristina Göller, Ewa Zarzycka, Hendrik Nogai
Journal: Blood
Blood (2023) 142 (Supplement 1): 2800.
https://doi.org/10.1182/blood-2023-189064
Published: 2023
Journal Articles

Targeting CDK8/CDK19 to Disrupt Leukemic Stem Cell-like Population in Acute Myeloid Leukemia: Exploring RVU120 As a Promising Frontline Therapy

Milena Mazan, Urszula Pakulska, Adrianna Moszyńska, Agnieszka Sroka-Porada, Krzysztof Tomasz Szade, Michał Mikula, Magdalena Kozakowska, Przemysław Juszczyński, Katarzyna Wiklik, Kristina Göller, Marta Obacz, Camille N. Abboud, Jan Maciej Zaucha, Ewa Lech Marańda, Noemi Angelosanto, Hendrik Nogai, Tomasz Rzymski
Journal: Blood
Blood (2023) 142 (Supplement 1): 4175.
https://doi.org/10.1182/blood-2023-188866
Published: 2023
Journal Articles

CDK 8/19 Kinase Inhibitor RVU120 in Patients with AML or Higher-Risk MDS: Safety and Efficacy Results from New Dose Escalation Cohorts

Camille Abboud, Sr., Jan Maciej Zaucha, Scott R. Solomon, Terrence Bradley, Elie Mouhayar, Noemi Angelosanto, Hendrik Nogai, Renata Dudziak, Tomasz Rzymski, Peter Littlewood, Krzysztof Brzózka, Axel Glasmacher, Gautam Borthakur, Howard A. Burris, Sr., Ewa Lech Marańda
Journal: Blood
Blood (2022) 140 (Supplement 1): 6228–6229.
https://doi.org/10.1182/blood-2022-163150
Published: 2022
Journal Articles

Multiomics Analysis Confirms Effective Target Engagement for RVU120 - a First-in-Class CDK8/19 Kinase Inhibitor in AML and MR-MDS Patients and Reveals the Mechanism of Action

Tomasz Rzymski, Agnieszka Sroka-Porada, Magdalena Kozakowska, Urszula Głowniak-Kwitek, Karolina Bukowska-Strakova, Marta Obacz, Peter Littlewood, Kamil Kuś, Kristina Goller, Kinga Kęska, Urszula Pakulska, Kamila Kozłowska-Tomczyk, Monika Madej, Milena Mazan, Przemyslaw Juszczynski, Jan M. Zaucha, Agnieszka Zarzycka, Noemi Angelosanto, Hendrik Nogai, Krzysztof Brzózka
Journal: Blood
Blood (2022) 140 (Supplement 1): 5939–5940.
https://doi.org/10.1182/blood-2022-168906
Published: 2022
Journal Articles

IκB-ζ controls the constitutive NF-κB target gene network and survival of ABC DLBCL

Hendrik Nogai, Sören-Sebastian Wenzel, Stephan Hailfinger, Michael Grau, Eva Kaergel, Volkhard Seitz, Brigitte Wollert-Wulf, Matthias Pfeifer, Annette Wolf, Mareike Frick, Kerstin Dietze, Hannelore Madle, Alexander Tzankov, Michael Hummel, Bernd Dörken, Claus Scheidereit, Martin Janz, Peter Lenz, Margot Thome, Georg Lenz
Journal: Blood
Blood (2013) 122 (13): 2242–2250.
https://doi.org/10.1182/blood-2013-06-508028
Published: 2013
Includes: Supplemental data