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Ewa Zarzycka
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Journal Articles

Preclinical and Clinical Evidence for Erythroid-Stimulating Activity of RVU120 CDK8/19 Inhibitor in AML and MDS

Noemi Angelosanto, Ewa Lech Marańda, Jan Maciej Zaucha, Camille N. Abboud, Agnieszka Sroka-Porada, Wiktoria Ogrodzińska, Magdalena Kozakowska, Urszula Głowniak-Kwitek, Karolina Bukowska-Strakova, Tomasz Rzymski, Milena Mazan, Urszula Pakulska, Kristina Göller, Ewa Zarzycka, Hendrik Nogai
Journal: Blood
Blood (2023) 142 (Supplement 1): 2800.
https://doi.org/10.1182/blood-2023-189064
Published: 2023
Journal Articles

Novel Clinically Useful Inhibitor of Mediator Complex, RVU120, Relives Differentiation Block in MDS/AML

Opeyemi Ajibade, Urszula Pakulska, Emma Rabinovich, Ariel Fromowitz, Srabani Sahu, Sarah Aminov, Nandini Ramachandra, Srinivas Aluri, Shanisha Gordon Mitchell, Milagros Carbajal, Kinga Keska-Izworska, Michał Combik, Marta Obacz, Elżbieta Adamczyk, Jan M. Zaucha, Ewa Zarzycka, Przemyslaw Juszczynski, Jacqueline Boultwood, Andrea Pellagatti, Kith Pradhan, Ulrich Steidl, Aditi Shastri, Rongbao Zhao, Milena Mazan, Tomasz Rzymski, Amit Verma
Journal: Blood
Blood (2023) 142 (Supplement 1): 3225.
https://doi.org/10.1182/blood-2023-186227
Published: 2023
Journal Articles

A Phase 1 Dose-Escalation Study of the Cladribine Added to CPX-351 in Patients with Relapsed/Refractory Acute Myeloid Leukemia (AML) - the Polish Adult Leukemia Group AML-1/2018 Study

Agnieszka Wierzbowska, Agnieszka Pluta, Piotr Stelmach, Kamil Brzozowski, Magdalena Czemerska, Marta Sobas, Justyna Rybka, Tomasz Wróbel, Ewa Zarzycka, Witold Prejzner, Jan M. Zaucha, Andrzej Szczepaniak, Lidia Gil, Sebastian Giebel
Journal: Blood
Blood (2023) 142 (Supplement 1): 5914.
https://doi.org/10.1182/blood-2023-181633
Published: 2023
Journal Articles

Molecular Characterization of Clinical Response and Relapse in Patients with IDH1 m ND-AML Treated with Ivo+AZA in the AGILE Study

Hartmut Döhner, Dylan M. Marchione, Sung Choe, Pau Montesinos, Christian Recher, Susana Vives, Ewa Zarzycka, Jianxiang Wang, Claudio Cerchione, Michael Heuser, Rodrigo T. Calado, Andre C. Schuh, Su-Peng Yeh, Adolfo De La Fuente, Jianan Hui, Prapti Patel, Diego A. Gianolio, Scott R. Daigle, Courtney D. DiNardo, Stephane De Botton
Journal: Blood
Blood (2022) 140 (Supplement 1): 539–542.
https://doi.org/10.1182/blood-2022-159473
Published: 2022
Journal Articles

Emicizumab in Management of Hemophilia_A Patients with High Titer FVIII Inhibitor - Real-World Evidence from Poland

Jerzy Windyga, Joanna Zdziarska, Ewa Stefanska-Windyga, Ewa Chmielewska, Krzysztof Chojnowski, Michal Jamrozik, Aleksandra Kostyra, Justyna Kozinska, Halyna Krainiak, Jolanta Oleksiuk, Joanna Rupa-Matysek, Ewa Zarzycka, Anna Buczma
Journal: Blood
Blood (2022) 140 (Supplement 1): 5621–5622.
https://doi.org/10.1182/blood-2022-163567
Published: 2022
Journal Articles

A Phase 1 Dose-Escalation Study of the Cladribine Added to CPX-351 in Patients with Relapsed/Refractory Acute Myeloid Leukemia (AML) a Study of the Polish Adult Leukemia Group (AML-1/2018): Preliminary Results of the Dose Escalation Stage

Agnieszka Wierzbowska, Agnieszka Pluta, Piotr Stelmach, Marta Anna Sobas, Justyna Rybka, Tomasz Wróbel, Ewa Zarzycka, Witold Prejzner, Jan Zaucha, Andrzej Szczepaniak, Lidia Gil, Sebastian Giebel
Journal: Blood
Blood (2022) 140 (Supplement 1): 6165–6166.
https://doi.org/10.1182/blood-2022-163109
Published: 2022
Journal Articles

A Comparison of Outcomes in Patients with Secondary Acute Promyelocytic Leukemia (APL) and De Novo APL - a Case-Match Retrospective Analysis of Polish Adult Leukemia Group (PALG)

Agnieszka Pluta, Marta Anna Sobas, Damian Mikulski, Kinga Krawiec, Magdalena Czemerska, Bozena Katarzyna Budziszewska, Tomasz Wróbel, Marzena Watek, Ewa Lech-Marańda, Tomasz Gromek, Dorota Hawrylecka, Marek Hus, Ewa Zarzycka, Jan Zaucha, Anna Armatys, Grzegorz Helbig, Jolanta Oleksiuk, Jaroslaw Piszcz, Andrzej Szczepaniak, Lidia Gil, Rafal Becht, Wojciech Fendler, Sebastian Giebel, Agnieszka Wierzbowska
Journal: Blood
Blood (2022) 140 (Supplement 1): 3206–3207.
https://doi.org/10.1182/blood-2022-166227
Published: 2022
Journal Articles

AGILE: A Global, Randomized, Double-Blind, Phase 3 Study of Ivosidenib + Azacitidine Versus Placebo + Azacitidine in Patients with Newly Diagnosed Acute Myeloid Leukemia with an IDH1 Mutation

Pau Montesinos, Christian Recher, Susana Vives, Ewa Zarzycka, Jianxiang Wang, Giambattista Bertani, Michael Heuser, Rodrigo T. Calado, Andre C. Schuh, Su-Peng Yeh, Scott R. Daigle, Jianan Hui, Vickie Zhang, Shuchi S. Pandya, Diego A. Gianolio, Stephane de Botton, Hartmut Döhner
Journal: Blood
Blood (2021) 138 (Supplement 1): 697.
https://doi.org/10.1182/blood-2021-147805
Published: 2021
Journal Articles

RVU120 (SEL120) CDK8/19 Inhibitor - a Drug Candidate for the Treatment of MDS Can Induce Erythroid Differentiation

Urszula Pakulska, Marta Obacz, Kristina Goller, Michal Combik, Kinga Keska, Jan Zaucha, Ewa Zarzycka, Milena Mazan, Michal Mikula, Magdalena Cybulska, Anna Polak, Przemyslaw Juszczynski, Johan Flygare, Jun Chen, Krzysztof Brzozka, Marcus Järås, Katarzyna Dziedzic, Noemi Angelosanto, Setareh Shamsili, Tomasz Rzymski
Journal: Blood
Blood (2021) 138 (Supplement 1): 1518.
https://doi.org/10.1182/blood-2021-150662
Published: 2021
Journal Articles

The Efficacy and Safety of Low-Dose Inotuzumab Ozogamicin in Patients with Relapsed or Refractory Acute Lymphoblastic Leukemia: Interim Results of a Phase 4 Study

Muhit Özcan, Ryan D. Cassaday, Pawan Singh, Ewa Zarzycka, Xin Zhang, Eric Nègre, Erik Vandendries, Fevzi Altuntas
Journal: Blood
Blood (2021) 138 (Supplement 1): 1208.
https://doi.org/10.1182/blood-2021-150001
Published: 2021