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Journal Articles

Safety and Efficacy Results from CLI120-001 a Phase 1 Study in RR-AML and HR-MDS: Update from Higher Dose Levels

Ewa Lech Marańda, Elżbieta Patkowska, Natalia Jakacka, Camille N. Abboud, Howard A. Burris, Scott R. Solomon, Noemi Angelosanto, Tomasz Rzymski, Peter Littlewood, Kamil Kuś, Agnieszka Sroka-Porada, Renata Dudziak, Hendrik Nogai, Axel Glasmacher, Terrence Bradley, Gautam Borthakur, Elie Mouhayar, Paweł Steckiewicz, Sylwia Kościółek- Zgódka, Agata Szymańska, Jan Maciej Zaucha
Journal: Blood
Blood (2023) 142 (Supplement 1): 2913.
https://doi.org/10.1182/blood-2023-186620
Published: 2023
Journal Articles

Phase 1/2 Study of TP-3654, a Selective PIM1 Kinase Inhibitor: Preliminary Data Showed Clinical Activity and Cytokine Reductions in Relapsed/Refractory Myelofibrosis Patients

Lindsay A.M Rein, Firas El Chaer, Junichiro Yuda, Kazuya Shimoda, James McCloskey, Akiyoshi Takami, Tamanna Haque, Michiko Ichii, Shuichi Shirane, Masafumi Fukaya, Joseph M. Scandura, Terrence Bradley, Pankit Vachhani, Takayuki Tabayashi, Steven Green, Stanley Cheung, Prithviraj Bose, Sharad Khurana, Casey L. O'Connell, Idoroenyi Amanam, David M. Ross, Sujan Kabir, Masataka Seki, Mark Wade, Vishnu Peddagali, Zhonggai Li, Jatin Shah, Raajit K. Rampal
Journal: Blood
Blood (2023) 142 (Supplement 1): 626.
https://doi.org/10.1182/blood-2023-180164
Published: 2023
Journal Articles

Outcomes of Patients with Accelerated/Blast-Phase MPNs That Received Allogeneic Stem-Cell Transplant in the Current Era of Myeloid Therapies

Anand Ashwin Patel, James J. Yoon, Hannah Johnston, Marta Beata Davidson, Auro Viswabandya, Rory M. Shallis, Evan C. Chen, Madelyn Burkart, Timothy S. Oh, Sunil G. Iyer, Ellen Madarang, Chandrasekar Muthiah, Raven Dean, Joshua Kassner, Raajit K. Rampal, Guru Subramanian Guru Murthy, Terrence Bradley, Yasmin Abaza, Jacqueline S. Garcia, Vikas Gupta, Kristen Marie Pettit, John Cursio, Olatoyosi Odenike
Journal: Blood
Blood (2023) 142 (Supplement 1): 3192.
https://doi.org/10.1182/blood-2023-174790
Published: 2023
Journal Articles

CDK 8/19 Kinase Inhibitor RVU120 in Patients with AML or Higher-Risk MDS: Safety and Efficacy Results from New Dose Escalation Cohorts

Camille Abboud, Sr., Jan Maciej Zaucha, Scott R. Solomon, Terrence Bradley, Elie Mouhayar, Noemi Angelosanto, Hendrik Nogai, Renata Dudziak, Tomasz Rzymski, Peter Littlewood, Krzysztof Brzózka, Axel Glasmacher, Gautam Borthakur, Howard A. Burris, Sr., Ewa Lech Marańda
Journal: Blood
Blood (2022) 140 (Supplement 1): 6228–6229.
https://doi.org/10.1182/blood-2022-163150
Published: 2022
Journal Articles

MYF1001: An Open Label, Dose Escalation and Expansion, Phase 1/1b Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics and Clinical Activity of Imetelstat in Combination with Ruxolitinib in Patients with Intermediate 1, Intermediate 2 or High-Risk Myelofibrosis

Terrence Bradley, Andrew Kuykendall, Rami S. Komrokji, Tymara Berry, Souria Dougherty, Laurie Sherman, Lixian Peng, Fei Huang, Ying Wan, Faye Feller, John Mascarenhas
Journal: Blood
Blood (2022) 140 (Supplement 1): 3941–3942.
https://doi.org/10.1182/blood-2022-159614
Published: 2022
Journal Articles

Toxicity and Outcomes in Octo- and Nonagenarians with AML Treated with Venetoclax and Hypomethylating Agent Therapy

Ellen Madarang, Jillian Lykon, Wei Zhao, Mikkael A. Sekeres, Terrence Bradley, Namrata Sonia Chandhok, Justin Taylor, Tulay Koru-Sengul, Sunil G. Iyer, Jacopo Nanni, Cristina Papayannidis, Ryan M Miller, Ashwin Kishtagari, Michael R. Savona, Jason Gilbert, Daniel A. Pollyea, David A. Sallman, Najla Al Ali, Rami S. Komrokji, Justin Watts
Journal: Blood
Blood (2022) 140 (Supplement 1): 3306–3308.
https://doi.org/10.1182/blood-2022-170771
Published: 2022
Journal Articles

Outcomes of Patients with Accelerated/Blast-Phase Myeloproliferative Neoplasms in the Current Era of Myeloid Therapies

Anand Ashwin Patel, James J. Yoon, Hannah Johnston, Evan C. Chen, Madelyn Burkart, Timothy Seijung Oh, Sunil G. Iyer, Ellen Madarang, Iyana Gross, Terrence Bradley, Yasmin Abaza, Jacqueline S. Garcia, Rory Michael Shallis, Guru Subramanian Guru Murthy, Vikas Gupta, Kristen M. Pettit, John Cursio, Olatoyosi Odenike
Journal: Blood
Blood (2022) 140 (Supplement 1): 6860–6862.
https://doi.org/10.1182/blood-2022-157603
Published: 2022
Journal Articles

A Phase 2 Study of the LSD1 Inhibitor Bomedemstat (IMG-7289) for the Treatment of Advanced Myelofibrosis (MF): Updated Results and Genomic Analyses

Kristen M. Pettit, Harinder Gill, Abdulraheem Yacoub, Terrence Bradley, Aaron T. Gerds, Maciej Tatarczuch, Jake Shortt, Natasha Joan Curtin, James M. Rossetti, Kate Burbury, Adam J Mead, Joachim R Göthert, Steffen Koschmieder, Matt Reyer, Benjamin Siranosian, Georges Natsoulis, William S Stevenson, Joanne Ewing, Joseph M. Chacko, Elisa Rumi, Anna B. Halpern, Francesca Palandri, Nicola Vianelli, Francesco Passamonti, Ruben Mesa, Monia Marchetti, Claire Harrison, Alessandro M. Vannucchi, Justin Watts, David M Ross, Moshe Talpaz, Hugh Young Rienhoff, Jr.
Journal: Blood
Blood (2022) 140 (Supplement 1): 9717–9720.
https://doi.org/10.1182/blood-2022-167122
Published: 2022
Journal Articles

Octogenarians with AML Can Have Durable Remissions with Venetoclax and Hypomethylating Agent Therapy Despite Significant Dose Reductions

Ellen Madarang, Jillian Lykon, Wenhui Li, Sunil Iyer, Michele Stanchina, Nina Nguyen, Terrence Bradley, Mikkael A. Sekeres, Justin Taylor, Namrata Sonia Chandhok, Justin Watts
Journal: Blood
Blood (2021) 138 (Supplement 1): 1259.
https://doi.org/10.1182/blood-2021-151738
Published: 2021
Journal Articles

Use of High Dose Cytarabine (HiDAC) for Post-Remission or Re-Induction Therapy Is Safe and Effective in Select Older AML Patients

Jillian Lykon, Ellen Madarang, Nina Nguyen, Wenhui Li, Sunil G. Iyer, Michele Stanchina, Terrence Bradley, Justin Taylor, Namrata Sonia Chandhok, Mikkael A. Sekeres, Justin Watts
Journal: Blood
Blood (2021) 138 (Supplement 1): 4422.
https://doi.org/10.1182/blood-2021-153143
Published: 2021
Journal Articles

Venetoclax in Combination with Gilteritinib Demonstrates Molecular Clearance of FLT3 mutation in Relapsed/Refractory FLT3 -Mutated Acute Myeloid Leukemia

Naval Daver, Alexander E. Perl, Joseph Maly, Mark Levis, Ellen Ritchie, Mark R. Litzow, James McCloskey, Catherine C. Smith, Gary J. Schiller, Terrence Bradley, Ramon V. Tiu, Kiran Naqvi, Monique Dail, Satya Siddani, Jing Wang, Brenda Chyla, Paul Lee, Jessica K. Altman
Journal: Blood
Blood (2021) 138 (Supplement 1): 691.
https://doi.org/10.1182/blood-2021-150743
Published: 2021
Journal Articles

CLI120-001 Phase Ib Study of RVU120(SEL120) in Patients with AML and High Risk MDS: Updated Safety/Efficacy Results from Initial Dose Escalation

Camille Abboud, Sr., Gautam Borthakur, Scott R. Solomon, Howard A. Burris, Sr., Terrence Bradley, JAN Maciej Zaucha, Sr., Ewa Lech-Marańda, Krzysztof Brzozka, Tomasz Rzymski, Peter Littlewood, Elie Mouhayar, Setareh Shamsili, Noemi Angelosanto
Journal: Blood
Blood (2021) 138 (Supplement 1): 3418.
https://doi.org/10.1182/blood-2021-151030
Published: 2021
Journal Articles

Combination Venetoclax and Selinexor Effective in Relapsed/Refractory Multiple Myeloma with Translocation t(11;14)

Nina Nguyen, Sana Chaudhry, Tulasigeri M Totiger, Skye Montoya, Jumana Afaghani, Terrence Bradley, Francesco Maura, Dickran Kazandjian, Jennifer R Chapman, Ola Landgren, James E. Hoffman, Justin Taylor
Journal: Blood
Blood (2021) 138 (Supplement 1): 2270.
https://doi.org/10.1182/blood-2021-146925
Published: 2021
Journal Articles

Outcomes for Hispanic Patients with Acute Leukemia Treated at Academic Centers

Namrata Sonia Chandhok, Ameena Shrestha, Justin M Watts, Terrence Bradley, Mikkael A. Sekeres
Journal: Blood
Blood (2021) 138 (Supplement 1): 2282.
https://doi.org/10.1182/blood-2021-151250
Published: 2021
Journal Articles

A Phase 2 Study of the LSD1 Inhibitor Img-7289 (bomedemstat) for the Treatment of Advanced Myelofibrosis

Harinder Gill, Abdulraheem Yacoub, Kristen M. Pettit, Terrence Bradley, Aaron T. Gerds, Maciej Tatarczuch, Jake Shortt, Natasha Joan Curtin, James M. Rossetti, Kate Burbury, Adam J. Mead, Joachim R. Göthert, Steffen Koschmieder, Amber Jones, Jennifer Peppe, Georges Natsoulis, Wan-Jen Hong, William S. Stevenson, Joanne Ewing, Claire N. Harrison, Alessandro Vannucchi, Justin Watts, David M Ross, Moshe Talpaz, Hugh Young Rienhoff, Jr.
Journal: Blood
Blood (2021) 138 (Supplement 1): 139.
https://doi.org/10.1182/blood-2021-148682
Published: 2021
Journal Articles

Efficacy and Safety of Venetoclax in Combination with Gilteritinib for Relapsed/Refractory FLT3 -Mutated Acute Myeloid Leukemia in the Expansion Cohort of a Phase 1b Study

Naval Daver, MD, Jessica K. Altman, MD, Joseph Maly, MD, Mark Levis, MD PhD, Ellen Ritchie, MD, Mark Litzow, MD, James K. McCloskey, MD, Catherine C. Smith, MD, Gary J. Schiller, MD, Terrence Bradley, MD, Ramon V. Tiu, MD, Wan-Jen Hong, MD, Bo Tong, PhD, Qin Qin, MS, Kimberley Dilley, MD MPH, Alexander E. Perl, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 20–22.
https://doi.org/10.1182/blood-2020-139705
Published: 2020
Journal Articles

Mutational Frequency in Hispanic Vs. Non-Hispanic Patients with Acute Myeloid Leukemia (AML)

Jorge Monge, MD, Christine Vaupel, PhD, Ronan T Swords, MD PhD FRCPI, FRCPath, Terrence Bradley, MD, Ryan Chapman, DO, Naiomi Gunaratne, Jennifer R Chapman, MD, Francisco Vega, MD PhD, Eric Padron, MD, Fernando Vargas, MD, Jeff Hall, PhD, Justin M Watts, MD
Journal: Blood
Blood (2016) 128 (22): 2796.
https://doi.org/10.1182/blood.V128.22.2796.2796
Published: 2016
Journal Articles

Early Detection of Myelodysplastic Syndromes: Maximizing the Utility of Automated Hematology

Yamina Lilliana Carattini, MCLS, Terrence Bradley, MD, Fernando Vargas, MD, Justin M Watts, MD, Jennifer R Chapman, MD, German Campuzano-Zuluaga, MD, Francisco Vega, MD PhD, Deukwoo Kwon, PhD, Ronan T Swords, MD PhD FRCPI, FRCPath
Journal: Blood
Blood (2016) 128 (22): 5527.
https://doi.org/10.1182/blood.V128.22.5527.5527
Published: 2016