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Georges Natsoulis
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Journal Articles

Bomedemstat (IMG-7289), an LSD1 Inhibitor, Manages the Signs and Symptoms of Essential Thrombocythemia (ET) While Reducing the Burden of Cells Homozygous for Driver Mutations

Joachim R. Goethert, Harinder Gill, Francesca Palandri, David M. Ross, Tara Cochrane, Stephen R. Larsen, Anna B. Halpern, Jake Shortt, James M. Rossetti, James Liang, Monia Marchetti, Andrew J. Wilson, Andrew Innes, Merit Hanna, William S. Stevenson, Alessandro M. Vannucchi, Maria Kleppe, Georges Natsoulis, Claire N Harrison, Hugh Young Rienhoff Jr.
Journal: Blood
Blood (2023) 142 (Supplement 1): 747.
https://doi.org/10.1182/blood-2023-179329
Published: 2023
Journal Articles

Mutational Analysis of the Genome Stability Factor BOD1L1 in Myeloproliferative Neoplasm

Martin R Higgs, Sofia Browne, Ryan Collinson, Kathy Fuller, Wendy N. Erber, Maria Kleppe, Ben Sirnosian, Georges Natsoulis, Belinda Guo, Hugh Young Rienhoff Jr.
Journal: Blood
Blood (2023) 142 (Supplement 1): 5677.
https://doi.org/10.1182/blood-2023-179125
Published: 2023
Journal Articles

Somatic Mutational Landscape of Hereditary Hematopoietic Malignancies Associated with Germline Variants in RUNX1 , GATA2 and DDX41

Anna L. Brown, Claire Homan, Michael W. Drazer, Kai Yu, David Lawrence, Jinghua Feng, Luis Arriola-Martinez, Matthew Pozsgai, Kelsey McNeely, Thuong Ha, Parvathy Venugopal, Peer Arts, Sarah King-Smith, Jesse JC Cheah, Mark Armstrong, Csaba Bödör, Paul Wang, Alan B. Cantor, Mario Cazzola, Erin Degelman, Courtney D. DiNardo, Nicolas Duployez, Remi Favier, Stefan Fröhling, Ana Rio-Machin, Jeffery M. Klco, Alwin Krämer, Mineo Kurokawa, Joanne Lee, Luca Malcovati, Neil V Morgan, Georges Natsoulis, Carolyn Owen, Keyur P. Patel, Claude Preudhomme, Hana Raslova, Hugh Young Rienhoff, Jr., Tim Ripperger, Rachael Schulte, Kiran Tawana, Elvira Deolinda Rodrigues Pereira Velloso, Benedict Yan, Raman Sood, Amy Hsu, Steven M. Holland, Kerry Phillips, Nicola Poplawski, Milena Babic, Erika M Kwon Kim, Andrew H. Wei, Cecily Forsyth, Helen Mar Fan, Ian D Lewis, Julian Cooney, Rachel Susman, Lucy C Fox, Piers Blombery, Deepak Singhal, Devendra Hiwase, Andreas W Schreiber, Christopher N Hahn, Hamish S Scott, Paul P. Liu, Lucy A. Godley
Journal: Blood
Blood (2022) 140 (Supplement 1): 4030–4033.
https://doi.org/10.1182/blood-2022-167600
Published: 2022
Journal Articles

A Phase 2 Study of the LSD1 Inhibitor Bomedemstat (IMG-7289) for the Treatment of Advanced Myelofibrosis (MF): Updated Results and Genomic Analyses

Kristen M. Pettit, Harinder Gill, Abdulraheem Yacoub, Terrence Bradley, Aaron T. Gerds, Maciej Tatarczuch, Jake Shortt, Natasha Joan Curtin, James M. Rossetti, Kate Burbury, Adam J Mead, Joachim R Göthert, Steffen Koschmieder, Matt Reyer, Benjamin Siranosian, Georges Natsoulis, William S Stevenson, Joanne Ewing, Joseph M. Chacko, Elisa Rumi, Anna B. Halpern, Francesca Palandri, Nicola Vianelli, Francesco Passamonti, Ruben Mesa, Monia Marchetti, Claire Harrison, Alessandro M. Vannucchi, Justin Watts, David M Ross, Moshe Talpaz, Hugh Young Rienhoff, Jr.
Journal: Blood
Blood (2022) 140 (Supplement 1): 9717–9720.
https://doi.org/10.1182/blood-2022-167122
Published: 2022
Journal Articles

A Phase 2 Study of the LSD1 Inhibitor Img-7289 (bomedemstat) for the Treatment of Essential Thrombocythemia (ET)

Francesca Palandri, Nicola Vianelli, David M Ross, Tara Cochrane, Steven W Lane, Stephen R Larsen, Aaron T. Gerds, Anna B. Halpern, Jake Shortt, James M. Rossetti, Kristen M. Pettit, Amber Jones, Jennifer Peppe, Georges Natsoulis, Willis Navarro, Wan-Jen Hong, William S. Stevenson, Claire N. Harrison, Moshe Talpaz, Hugh Young Rienhoff, Jr.
Journal: Blood
Blood (2021) 138 (Supplement 1): 386.
https://doi.org/10.1182/blood-2021-148210
Published: 2021
Journal Articles

A Phase 2 Study of the LSD1 Inhibitor Img-7289 (bomedemstat) for the Treatment of Advanced Myelofibrosis

Harinder Gill, Abdulraheem Yacoub, Kristen M. Pettit, Terrence Bradley, Aaron T. Gerds, Maciej Tatarczuch, Jake Shortt, Natasha Joan Curtin, James M. Rossetti, Kate Burbury, Adam J. Mead, Joachim R. Göthert, Steffen Koschmieder, Amber Jones, Jennifer Peppe, Georges Natsoulis, Wan-Jen Hong, William S. Stevenson, Joanne Ewing, Claire N. Harrison, Alessandro Vannucchi, Justin Watts, David M Ross, Moshe Talpaz, Hugh Young Rienhoff, Jr.
Journal: Blood
Blood (2021) 138 (Supplement 1): 139.
https://doi.org/10.1182/blood-2021-148682
Published: 2021
Journal Articles

A Phase 2a Study of the LSD1 Inhibitor Img-7289 (bomedemstat) for the Treatment of Myelofibrosis

Kristen Pettit, MD, Aaron T. Gerds, MD MS, Abdulraheem Yacoub, MD, Justin M. Watts, MD, Maciej Tartaczuch, MD, Terrence J Bradley, MD, Jake Shortt, MBBS FRACP FRCPA PhD, William S. Stevenson, MBBS,PhD, Natasha Joan Curtin, MDFRACP,FRCPA, James M. Rossetti, DO, Kate Burbury, MBBS, FRACP, FRCPA, DPhil, Georges Natsoulis, PhD, Amber Jones, MA, Moshe Talpaz, MD, Jennifer Peppe, BS, David M Ross, MD PhD, Hugh Young Rienhoff, Jr., MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 556.
https://doi.org/10.1182/blood-2019-123244
Published: 2019
Journal Articles

An Enhanced Sensitivity DNA Sequencing Protocol for the Detection in AML of Measurable Residual Disease (MRD) Applicable for All Mutations

Hugh Y. Rienhoff, Jr., MD, Georges Natsoulis, PhD, Amber Jones, MA, Jennifer Peppe, BS, Ru Cao, PhD, Khalid Hanif, PhD, Justin M. Watts, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 5279.
https://doi.org/10.1182/blood-2018-99-115505
Published: 2018
Journal Articles

Development of a Data Portal for Aggregation and Analysis of Genomics Data in Familial Platelet Disorder with Predisposition to Myeloid Malignancy - the RUNX1.DB

Anna L. Brown, PhD BSc, Mark Armstrong, MSc, David Lawrence, Paul Wang, Peer Arts, PhD, Nicolas Duployez, PharmD, PhD, Jane Churpek, MD, Kiran Tawana, MD, Erin Degelman, MSc, BSc, Georges Natsoulis, PhD, Monica L. Guzman, PhD, Mrinal M. Patnaik, MD MBBS, Akiko Shimamura, MD PhD, Alan B. Cantor, MD PhD, Tim Ripperger, MD PhD, Brigitte Schlegelberger, MD PhD, Doris Steinemann, PhD, Courtney D. DiNardo, MD MSc, Cristina Mecucci, MD PhD, Elvira DRP Velloso, MD PhD, Fabio PS Santos, MD, Marcela CA Silva, Uma Borate, MD, Shannon K. McWeeney, PhD, Grzegorz Nalepa, MD PhD, Susanne Ragg, MD PhD, Erika Mijin Kwon, PhD, Anupriya Agarwal, PhD, Stephen Langabeer, PhD, Jeffery M. Klco, MD PhD, Jun J. Yang, PhD, Cecily Forsyth, FRACP, FRCPA, MBBS, Sally Mapp, MD PhD, Helen Mar Fan, MD, Lesley Rawlings, PhD, Rachel Susman, Sue Morgan, FRACP, FRCPA, MBBS, Andrew H Wei, MBBS,PhD, Inderjeet Dokal, MD, Tom Vulliamy, Devendra K Hiwase, MBBS, MD FRACP, FRCPA, PhD, Deepak Singhal, MBBS, MD FRACP, FRCPA, Susan Branford, PhD, Elli Papaemmanuil, PhD, Jean Soulier, MDPhD, Stefan Fröhling, MD, Alwin Kramer, MD, Guy Sauvageau, MD PhD, Neil Morgan, Carolyn Owen, Csaba Bödör, PhD, Jude Fitzgibbon, Hugh Y. Rienhoff, Jr., MD, Mineo Kurokawa, MD PhD, Lucy Godley, MD PhD, Claude Preudhomme, Paul P Liu, MD PhD, Nicola Poplawski, MD, Christopher N. Hahn, PhD, Hamish S. Scott, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 5241.
https://doi.org/10.1182/blood-2018-99-118017
Published: 2018
Journal Articles

Identification of Novel LNK Mutations In Patients with Chronic Myeloproliferative Neoplasms and Related Disorders

Stephen T. Oh, M.D., Ph.D., Jacob M. Zahn, Ph.D., Carol D. Jones, B.A., Bing Zhang, M.D., M.S., Mignon L. Loh, M.D., Hagop Kantarjian, MD, Erin F. Simonds, B.S., Robert V. Bruggner, B.S., Parveen Abidi, Ph.D., Georges Natsoulis, Ph.D., John Bell, M.S., Jason Buenrostro, B.S., Garry P. Nolan, Ph.D., James L. Zehnder, M.D., Hanlee P. Ji, M.D., Jason Gotlib, M.D., M.S.
Journal: Blood
Blood (2010) 116 (21): 315.
https://doi.org/10.1182/blood.V116.21.315.315
Published: 2010