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Journal Articles

Genome-wide transcription factor–binding maps reveal cell-specific changes in the regulatory architecture of human HSPCs

Blood (2023) 142 (17): 1448–1462.

https://doi.org/10.1182/blood.2023021120

Published: 2023

Includes: Supplemental data

Journal Articles

Somatic Mutational Landscape of Hereditary Hematopoietic Malignancies Associated with Germline Variants in RUNX1 , GATA2 and DDX41

Anna L. Brown, Claire Homan, Michael W. Drazer, Kai Yu, David Lawrence, Jinghua Feng, Luis Arriola-Martinez, Matthew Pozsgai, Kelsey McNeely, Thuong Ha, Parvathy Venugopal, Peer Arts, Sarah King-Smith, Jesse JC Cheah, Mark Armstrong, Csaba Bödör, Paul Wang, Alan B. Cantor, Mario Cazzola, Erin Degelman, Courtney D. DiNardo, Nicolas Duployez, Remi Favier, Stefan Fröhling, Ana Rio-Machin, Jeffery M. Klco, Alwin Krämer, Mineo Kurokawa, Joanne Lee, Luca Malcovati, Neil V Morgan, Georges Natsoulis, Carolyn Owen, Keyur P. Patel, Claude Preudhomme, Hana Raslova, Hugh Young Rienhoff, Jr., Tim Ripperger, Rachael Schulte, Kiran Tawana, Elvira Deolinda Rodrigues Pereira Velloso, Benedict Yan, Raman Sood, Amy Hsu, Steven M. Holland, Kerry Phillips, Nicola Poplawski, Milena Babic, Erika M Kwon Kim, Andrew H. Wei, Cecily Forsyth, Helen Mar Fan, Ian D Lewis, Julian Cooney, Rachel Susman, Lucy C Fox, Piers Blombery, Deepak Singhal, Devendra Hiwase, Andreas W Schreiber, Christopher N Hahn, Hamish S Scott, Paul P. Liu, Lucy A. Godley

Blood (2022) 140 (Supplement 1): 4030–4033.

https://doi.org/10.1182/blood-2022-167600

Published: 2022

Journal Articles

Deleterious Germline Variants, Especially in the DNA Repair Pathway, Are Common in Patients with Non-Related Multiple Cancers, One of Them Being Hematological Malignancy

Blood (2019) 134 (Supplement_1): 1704.

https://doi.org/10.1182/blood-2019-126462

Published: 2019

Journal Articles

Therapy-Related Myeloid Neoplasms (T-MN) and Primary MDS (PMDS) Patients with Very Low (VL) or Low (L) IPSS-R Score Share Clinical and Biological Characteristics and Have Similar Outcome

Blood (2018) 132 (Supplement 1): 3078.

https://doi.org/10.1182/blood-2018-99-115828

Published: 2018

Journal Articles

Genetic Predisposition to Therapy-Related Myeloid Neoplasm By Rare, Deleterious Germline Variants in DNA Repair Pathway and Myeloid Driver Genes

Blood (2018) 132 (Supplement 1): 1802.

https://doi.org/10.1182/blood-2018-99-117815

Published: 2018

Journal Articles

Red Cell Alloimmunisation Is Associated with Increased Red Cell Transfusion Requirements in Myelodysplastic Syndrome

Rakchha Chhetri, MBBS, Amilia Wee, BSc (Hons), Romi Sinha, MBBS, Monika M Kutyna, MSc, Soumya Gupta, Lakshmi Nath, MDDM,FRCPA, Shriram V. Nath, MDDM, FRCPA, FRACP, Nicholas Wickham, FRCPA, FRACP, FRCPath, Ian D Lewis, MBBS,PhD, David M Ross, Luen Bik To, MBBS, FRACP, FRCPA, PhD, Deepak Singhal, MBBS, MDFRACP, FRCPA, David John Roxby, B App Sc, M App Sc, ARCPA, Devendra K Hiwase, MBBS, MD FRACP, FRCPA, PhD

Blood (2018) 132 (Supplement 1): 1826.

https://doi.org/10.1182/blood-2018-99-115848

Published: 2018

Journal Articles

A Geriatric Screening Tool (G8) Provides an Independent Prognostic Index for Azacitidine Treated Elderly MDS Patients

Angela Molga, MBBS, FRACP, Michelle Wall, Dip HE (Nursing), BA (Hons), MSc, PG Cert, Deepak Singhal, MBBS, MD FRCPA, FRACP, Rakchha Chhetri, MBBS, Amilia Wee, BSc (Hons), Lucy Cussans, Nimit Singhal, MBBS MDDM FRACP, Gillian Caughey, PhD, Luen Bik To, MBBS, FRACP, FRCPA, PhD, Peter Bardy, MBBS, FRACP, FRCPA, FRCPath, Sepehr Shakib, MBBS, FRACP, PhD, Ian D Lewis, MBBS, PhD FRACP, FRCPA, Timothy To, BSc, BMBS, FRACP, FAChPM, Devendra K Hiwase, MBBS, MD FRACP, FRCPA, PhD

Blood (2017) 130 (Supplement 1): 1692.

https://doi.org/10.1182/blood.V130.Suppl_1.1692.1692

Published: 2017

Journal Articles

Presence of Rare Germline Variants in Fanconi Anaemia Pathway Genes Confers a Poor Prognosis Comparable to TP53 Mutations in Therapy-Related Myeloid Neoplasms

Blood (2017) 130 (Supplement 1): 4231.

https://doi.org/10.1182/blood.V130.Suppl_1.4231.4231

Published: 2017

Journal Articles

Red Cell Alloimmunisation Is Associated with Development of Autoantibodies and Increased Red Cell Transfusion Requirements in Myelodysplastic Syndromes (MDS)

Deepak Singhal, MBBS, MD FRCPA, FRACP, Monika M Kutyna, MSc, Rakchha Chhetri, MBBS, Amilia Wee, BSc (Hons), Sophia Hague, Lakshmi Nath, MDDM,FRCPA, Shriram V Nath, MBBS, DM, FRCPA, Romi Sinha, MBBS, Nicholas Wickham, FRCPA,FRACP,FRCPath, Ian D Lewis, MBBS, PhD FRACP, FRCPA, David M Ross, MBBS, PhD FRACP, FRCPA, Peter G Bardy, MBBS, FRACP, FRCPA, FRCPath, Luen Bik To, MBBS, FRACP, FRCPA, PhD, John Reynolds, PhD, Erica Wood, David John Roxby, Devendra K Hiwase, MBBS, MD FRACP, FRCPA, PhD

Blood (2017) 130 (Supplement 1): 2411.

https://doi.org/10.1182/blood.V130.Suppl_1.2411.2411

Published: 2017

Journal Articles

Targeting sphingosine kinase 1 induces MCL1-dependent cell death in acute myeloid leukemia

Jason A. Powell, Alexander C. Lewis, Wenying Zhu, John Toubia, Melissa R. Pitman, Craig T. Wallington-Beddoe, Paul A. B. Moretti, Diana Iarossi, Saumya E. Samaraweera, Nik Cummings, Hayley S. Ramshaw, Daniel Thomas, Andrew H. Wei, Angel F. Lopez, Richard J. D’Andrea, Ian D. Lewis, Stuart M. Pitson

Blood (2017) 129 (6): 771–782.

https://doi.org/10.1182/blood-2016-06-720433

Published: 2017

Includes: Supplemental data

Journal Articles

High-Dose Cytarabine (HiDAC) Improves the Cure Rate of Patients with Newly Diagnosed Acute Myeloid Leukemia (AML): Is It Better to be Given As Induction Therapy or As Consolidation Therapy?

Anthony P Schwarer, MD MBBS (Hons), FRACP, FRCPA, Joel Wight, MBBS, Kathryn Jackson, MBBS, Ashanka Mahilal Beligaswatte, BA, MBBS, MD FRACP, FRCPA, Jason P Butler, MBBS, MMedSc, FRACP, FRCPA, Glen Kennedy, MBBS, FRACP, FRCPA, Louisa Martin, MBBS, Ian D. Lewis, MBBS PhD FRACP FRCPA, Devendra Hiwase, MBBS, FRACP, FRCPA, MD PhD, Daniela Zantomio, FRACP, FRCPA, MBBS, Simon Z. He, MBBS,FRACP,FRCPA, Andrew Grigg, MBBS, MD FRACP, FRCPA, Kirk Morris, FRACP FRCPA MBBS, Peter Mollee, MBBS, MMedSc, FRACP, FRCPA, Paula Marlton, MBBS

Blood (2016) 128 (22): 3989.

https://doi.org/10.1182/blood.V128.22.3989.3989

Published: 2016

Journal Articles

Hypermethylation of GADD45A Defines a Methylation Profile Distinct to Mutant IDH1/2 , and Correlates with More Aggressive AML

Blood (2016) 128 (22): 2877.

https://doi.org/10.1182/blood.V128.22.2877.2877

Published: 2016

Journal Articles

Rare Variants Affecting the Fanconi Anaemia DNA Repair Genes Associate with Increased Risk for AML

Kyaw Ze Ya Maung, BSc, Paul Leo, PhD, Anna L Brown, PhD, Mahmoud A Bassal, Bsc, BCompSc, Debora A. Casolari, PhD, Adam Ewing, B.A & PhD, Emma Duncan, PhD, Sarah C Bray, PhD, Evgeny Glazov, PhD, Luen Bik To, MBBS, FRACP, FRCPA, PhD, Russell Saal, MMSc, BSMedTech, Ian D Lewis, MBBS, PhD FRACP, FRCPA, Devinder S Gill, MBChB FRCPath MRCP, Paula Marlton, MBBS, FRACP, FRCPA, James X Gray, MD PhD, Thomas J Gonda, PhD, Richard D'Andrea, PhD

Blood (2016) 128 (22): 41.

https://doi.org/10.1182/blood.V128.22.41.41

Published: 2016

Journal Articles

Metabolic Profiling of Adult Acute Myeloid Leukemia (AML)

Blood (2016) 128 (22): 1684.

https://doi.org/10.1182/blood.V128.22.1684.1684

Published: 2016

Journal Articles

Expanded Phenotypic and Genetic Heterogeneity in the Clinical Spectrum of FPD-AML: Lymphoid Malignancies and Skin Disorders Are Common Features in Carriers of Germline RUNX1 Mutations

Anna L Brown, PhD, Christopher N Hahn, PhD, Catherine Carmichael, Ella Wilkins, Milena Babic, BMPharBio (Hons), Chan-Eng Chong, PhD, Xiao-Chun Li, Joelle Michaud, Ping Cannon, Nicola Poplawski, MBChB, DipPaed, FRACP, MD, Meryl Altree, Kerry Phillips, Louise Jaensch, Miriam Fine, Andreas W Schreiber, PhD, Jinghua Feng, PhD, Lesley Rawlings, PhD, Cassandra Vakulin, Carolyn Butcher, Richard D'Andrea, PhD, Ian D Lewis, MBBS, PhD FRACP, FRCPA, Nigel Patton, Cecily Forsyth, MBBS, FRACP, FRCPA, Sally Mapp, PhD MD, Helen Mar Fan, Rachel Susman, Sue Morgan, FRACP, FRCPA, MBBS, Julian Cooney, MD, Mark S Currie, MD, Uday R. Popat, MD, Kenneth Bradstock, MBBS, PhD, April D. Sorrell, MD, Carolyn J. Owen, MD MDes(UK), FRCPC, Marshall S Horwitz, MD PhD, Devendra Hiwase, MBBS, FRACP, FRCPA, MD PhD, Alwin Krämer, MD, Stefan Fröhling, MD, Lucy A Godley, MD PhD, Jane E Churpek, MD, Hamish S Scott, BSc, PhD FFSc (RCPA), FAHMS

Blood (2016) 128 (22): 1212.

https://doi.org/10.1182/blood.V128.22.1212.1212

Published: 2016

Journal Articles

The Genomic Landscape of Childhood and Adult Acute Erythroid Leukemia

Blood (2016) 128 (22): 39.

https://doi.org/10.1182/blood.V128.22.39.39

Published: 2016

Journal Articles

Changes of the Mutational Landscape in Relapsed Acute Myeloid Leukemia

Blood (2016) 128 (22): 599.

https://doi.org/10.1182/blood.V128.22.599.599

Published: 2016

Journal Articles

RBC-Transfusion Dependency Improves the Prognostic Value of the Revised-IPSS in MDS Patients: Analysis of South Australian and Dusseldorf MDS Registries

Deepak Singhal, MD FRCPA, Corinna Strupp, Rakchha Chhetri, MBBS, Monika M Kutyna, MSc, L Amilia Wee, B.Sc(Hons), Shriram V. Nath, FRCPA, DM, MD, Nicholas Wickham, FRCPA, FRACP, FRCPath, Chi-hung Hui, MBBS, MRCP, FRCPath, FRACP, FRCPA, James X Gray, MD PhD, David M. Ross, MBBS, PhD FRACP, FRCPA, Ian D Lewis, MBBS, PhD FRACP, FRCPA, Peter G Bardy, MBBS, FRACP, FRCPA, John Reynolds, PhD, Luen Bik To, MBBS, PhD, Devendra K Hiwase, MBBS, MD FRACP, FRCPA, PhD, Ulrich Germing

Blood (2016) 128 (22): 1998.

https://doi.org/10.1182/blood.V128.22.1998.1998

Published: 2016

Journal Articles

A Prospective Randomized Double Blind Phase 3 Clinical Trial of Anti- T Lymphocyte Globulin (ATLG) to Assess Impact on Chronic Graft-Versus-Host Disease (cGVHD) Free Survival in Patients Undergoing HLA Matched Unrelated Myeloablative Hematopoietic Cell Transplantation (HCT)

Blood (2016) 128 (22): 505.

https://doi.org/10.1182/blood.V128.22.505.505

Published: 2016

Journal Articles

The Frequency of Genetic Mutations in T-MN Is High and Comparable to Primary MDS but the Spectrum Is Different

Blood (2016) 128 (22): 3157.

https://doi.org/10.1182/blood.V128.22.3157.3157

Published: 2016

NARROW

Genome-wide transcription factor–binding maps reveal cell-specific changes in the regulatory architecture of human HSPCs

Somatic Mutational Landscape of Hereditary Hematopoietic Malignancies Associated with Germline Variants in RUNX1 , GATA2 and DDX41

Deleterious Germline Variants, Especially in the DNA Repair Pathway, Are Common in Patients with Non-Related Multiple Cancers, One of Them Being Hematological Malignancy

Therapy-Related Myeloid Neoplasms (T-MN) and Primary MDS (PMDS) Patients with Very Low (VL) or Low (L) IPSS-R Score Share Clinical and Biological Characteristics and Have Similar Outcome

Genetic Predisposition to Therapy-Related Myeloid Neoplasm By Rare, Deleterious Germline Variants in DNA Repair Pathway and Myeloid Driver Genes

Red Cell Alloimmunisation Is Associated with Increased Red Cell Transfusion Requirements in Myelodysplastic Syndrome

A Geriatric Screening Tool (G8) Provides an Independent Prognostic Index for Azacitidine Treated Elderly MDS Patients

Presence of Rare Germline Variants in Fanconi Anaemia Pathway Genes Confers a Poor Prognosis Comparable to TP53 Mutations in Therapy-Related Myeloid Neoplasms

Red Cell Alloimmunisation Is Associated with Development of Autoantibodies and Increased Red Cell Transfusion Requirements in Myelodysplastic Syndromes (MDS)

Targeting sphingosine kinase 1 induces MCL1-dependent cell death in acute myeloid leukemia

High-Dose Cytarabine (HiDAC) Improves the Cure Rate of Patients with Newly Diagnosed Acute Myeloid Leukemia (AML): Is It Better to be Given As Induction Therapy or As Consolidation Therapy?

Hypermethylation of GADD45A Defines a Methylation Profile Distinct to Mutant IDH1/2 , and Correlates with More Aggressive AML

Rare Variants Affecting the Fanconi Anaemia DNA Repair Genes Associate with Increased Risk for AML

Metabolic Profiling of Adult Acute Myeloid Leukemia (AML)

Expanded Phenotypic and Genetic Heterogeneity in the Clinical Spectrum of FPD-AML: Lymphoid Malignancies and Skin Disorders Are Common Features in Carriers of Germline RUNX1 Mutations

The Genomic Landscape of Childhood and Adult Acute Erythroid Leukemia

Changes of the Mutational Landscape in Relapsed Acute Myeloid Leukemia

RBC-Transfusion Dependency Improves the Prognostic Value of the Revised-IPSS in MDS Patients: Analysis of South Australian and Dusseldorf MDS Registries

A Prospective Randomized Double Blind Phase 3 Clinical Trial of Anti- T Lymphocyte Globulin (ATLG) to Assess Impact on Chronic Graft-Versus-Host Disease (cGVHD) Free Survival in Patients Undergoing HLA Matched Unrelated Myeloablative Hematopoietic Cell Transplantation (HCT)

The Frequency of Genetic Mutations in T-MN Is High and Comparable to Primary MDS but the Spectrum Is Different

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American Society of Hematology

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American Society of Hematology

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