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Hayley S. Ramshaw
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Journal Articles

Targeting sphingosine kinase 1 induces MCL1-dependent cell death in acute myeloid leukemia

Jason A. Powell, Alexander C. Lewis, Wenying Zhu, John Toubia, Melissa R. Pitman, Craig T. Wallington-Beddoe, Paul A. B. Moretti, Diana Iarossi, Saumya E. Samaraweera, Nik Cummings, Hayley S. Ramshaw, Daniel Thomas, Andrew H. Wei, Angel F. Lopez, Richard J. D’Andrea, Ian D. Lewis, Stuart M. Pitson
Journal: Blood
Blood (2017) 129 (6): 771–782.
https://doi.org/10.1182/blood-2016-06-720433
Published: 2017
Includes: Supplemental data
Journal Articles

Monoclonal antibody targeting of IL-3 receptor α with CSL362 effectively depletes CML progenitor and stem cells

Eva Nievergall, Hayley S. Ramshaw, Agnes S. M. Yong, Mark Biondo, Samantha J. Busfield, Gino Vairo, Angel F. Lopez, Timothy P. Hughes, Deborah L. White, Devendra K. Hiwase
Journal: Blood
Blood (2014) 123 (8): 1218–1228.
https://doi.org/10.1182/blood-2012-12-475194
Published: 2014
Includes: Supplemental data
Journal Articles

IL3-Receptor Signaling Is Dispensable For The Generation and Maintenance Of Jak2V617F-Induced Myeloproliferative Neoplasm (MPN

Therese Vu, Claudia Bruedigam, Rebecca Austin, Catherine Paine-Kuhn, Hayley S. Ramshaw, PhD, Angel F. Lopez, MBBS, PhD, Geoff Hill, MD, Ann Mullally, MD, Steven W Lane, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 2841.
https://doi.org/10.1182/blood.V122.21.2841.2841
Published: 2013
Journal Articles

Effective Elimination of CML Progenitor and Stem Cells Through Combination of α-CD123 Antibody-Dependent Cell-Mediated Cytotoxicity and Tyrosine Kinase Inhibitor Treatment

Eva Nievergall, PhD, Deborah L. White, PhD, FFSc(RCPA), Agnes S.M. Yong, MD, PhD, Hayley S. Ramshaw, PhD, Samantha J. Busfield, PhD, Gino Vairo, PhD, Angel F. Lopez, MBBS, PhD, Timothy P. Hughes, MD, MBBS, Devendra K. Hiwase, MBBS, MD, PhD, FRACP, FRCPA
Journal: Blood
Blood (2012) 120 (21): 32.
https://doi.org/10.1182/blood.V120.21.32.32
Published: 2012
Journal Articles

CSL362: A Monoclonal Antibody to Human Interleukin-3 Receptor (CD123), Optimized for NK Cell-Mediated Cytotoxicity of AML Stem Cells

Samantha J. Busfield, PhD, Mark Biondo, PhD, Mae Wong, PhD, Hayley S. Ramshaw, PhD, Erwin M Lee, PhD, Kirstee Martin, PhD, Souravi Ghosh, PhD, Hal Braley, Vesna Tomasetig, Con Panousis, PhD, Gino Vairo, PhD, Andrew W. Roberts, MBBS, PhD, Simon Z. He, MBBS, Naomi Sprigg, Daniel Thomas, MBBS, PhD, Mark DeWitte, VMD, Richard B. Lock, PhD, Angel F. Lopez, MBBS, PhD, Andrew Nash, PhD
Journal: Blood
Blood (2012) 120 (21): 3598.
https://doi.org/10.1182/blood.V120.21.3598.3598
Published: 2012
Journal Articles

Immune insufficiency during GVHD is due to defective antigen presentation within dendritic cell subsets

Kate A. Markey, Motoko Koyama, Rachel D. Kuns, Katie E. Lineburg, Yana A. Wilson, Stuart D. Olver, Neil C. Raffelt, Alistair L. J. Don, Antiopi Varelias, Renee J. Robb, Melody Cheong, Christian R. Engwerda, Raymond J. Steptoe, Hayley S. Ramshaw, Angel F. Lopez, Javier Vega-Ramos, Andrew M. Lew, Jose A. Villadangos, Geoffrey R. Hill, Kelli P. A. MacDonald
Journal: Blood
Blood (2012) 119 (24): 5918–5930.
https://doi.org/10.1182/blood-2011-12-398164
Published: 2012
Journal Articles

Sphingosine kinase regulates the rate of endothelial progenitor cell differentiation

Claudine S. Bonder, Wai Y. Sun, Tyson Matthews, Carlos Cassano, Xiaochun Li, Hayley S. Ramshaw, Stuart M. Pitson, Angel F. Lopez, P. Toby Coates, Richard L. Proia, Mathew A. Vadas, Jennifer R. Gamble
Journal: Blood
Blood (2009) 113 (9): 2108–2117.
https://doi.org/10.1182/blood-2008-07-166942
Published: 2009
Includes: Supplemental data
Journal Articles

CD123 (IL-3 Receptor α Chain) Neutralization by a Monoclonal Antibody Selectively Eliminates Human Acute Myeloid Leukemic Stem Cells.

Richard B. Lock, PhD, Liqing Jin, PhD, Erwin M. Lee, PhD, Hayley S. Ramshaw, PhD, Sam Busfield, PhD, Armando G. Peoppl, BSc, Lucy Wilkinson, BSc, Mark A. Guthridge, PhD, Andrew Boyd, PhD, David Gearing, PhD, Gino Vairo, PhD, Angel Lopez, MD, PhD, John E. Dick, PhD
Journal: Blood
Blood (2007) 110 (11): 161.
https://doi.org/10.1182/blood.V110.11.161.161
Published: 2007
Journal Articles

The Shc-binding site of the β c subunit of the GM-CSF/IL-3/IL-5 receptors is a negative regulator of hematopoiesis

Hayley S. Ramshaw, Mark A. Guthridge, Frank C. Stomski, Emma F. Barry, Lisa Ooms, Christina A. Mitchell, C. Glenn Begley, Angel F. Lopez
Journal: Blood
Blood (2007) 110 (10): 3582–3590.
https://doi.org/10.1182/blood-2007-01-070391
Published: 2007
Includes: Supplemental data
Journal Articles

Increased Recruitment of Hematopoietic Progenitor Cells Underlies the Ex Vivo Expansion Potential of FLT3 Ligand

David N. Haylock, Martyn J. Horsfall, Tracey L. Dowse, Hayley S. Ramshaw, Silvana Niutta, Sandra Protopsaltis, Li Peng, Christopher Burrell, Irene Rappold, Hans-Jorg Buhring, Paul J. Simmons
Journal: Blood
Blood (1997) 90 (6): 2260–2272.
https://doi.org/10.1182/blood.V90.6.2260
Published: 1997
Journal Articles

Cytokine-Facilitated Transduction Leads to Low-Level Engraftment in Nonablated Hosts

Ellen L.W. Kittler, Stefan O. Peters, Rowena B. Crittenden, Michelle E. Debatis, Hayley S. Ramshaw, F. Marc Stewart, Peter J. Quesenberry
Journal: Blood
Blood (1997) 90 (2): 865–872.
https://doi.org/10.1182/blood.V90.2.865
Published: 1997