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Saumya E. Samaraweera
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Journal Articles

Loss of the stress sensor GADD45A promotes stem cell activity and ferroptosis resistance in LGR4/HOXA9-dependent AML

Nunki Hassan, Hangyu Yi, Bilal Malik, Lucie Gaspard-Boulinc, Saumya E. Samaraweera, Debora A. Casolari, Janith Seneviratne, Anushree Balachandran, Tracy Chew, Alastair Duly, Daniel R. Carter, Belamy B. Cheung, Murray Norris, Michelle Haber, Maria Kavallaris, Glenn M. Marshall, Xu Dong Zhang, Tao Liu, Jianlong Wang, Dan A. Liebermann, Richard J. D’Andrea, Jenny Y. Wang
Journal: Blood
Blood (2024) 144 (1): 84–98.
https://doi.org/10.1182/blood.2024024072
Published: 2024
Includes: Supplemental data
Journal Articles

IDH -mutant myeloid neoplasms are associated with seronegative rheumatoid arthritis and innate immune activation

Lih En Hong, Mihir D. Wechalekar, Monika Kutyna, Annabelle Small, Kelly Lim, Chloe Thompson-Peach, Joule J. Li, Rakchha Chhetri, Hamish S. Scott, Anna Brown, Christopher N. Hahn, David T. Yeung, Salvia Sajid, Nirmal Robinson, Ranjeny Thomas, Susan Branford, Richard J. D’Andrea, Saumya E. Samaraweera, Mrinal Patnaik, Susanna Proudman, Daniel Thomas, Chung Hoow Kok, Mithun V. Shah, Devendra K. Hiwase
Journal: Blood
Blood (2024) 143 (18): 1873–1877.
https://doi.org/10.1182/blood.2023023593
Published: 2024
Includes: Supplemental data
Journal Articles

Childhood acute myeloid leukemia shows a high level of germline predisposition

Saumya E. Samaraweera, Paul P. S. Wang, Ka Leung Li, Debora A. Casolari, Jinghua Feng, Mark Pinese, Kyaw Ze Ya Maung, Paul Leo, Mark Cowley, Kelly Perkins, Amanda M. Smith, Jonathan Ellis, Amilia Wee, Devendra K. Hiwase, Hamish S. Scott, Andreas W. Schreiber, Anna L. Brown, Andrew J. Deans, David M. Ross, Andrew S. Moore, Thomas J. Gonda, Christopher N. Hahn, Richard J. D’Andrea
Journal: Blood
Blood (2021) 138 (22): 2293–2298.
https://doi.org/10.1182/blood.2021012666
Published: 2021
Includes: Supplemental data
Journal Articles

Targeting sphingosine kinase 1 induces MCL1-dependent cell death in acute myeloid leukemia

Jason A. Powell, Alexander C. Lewis, Wenying Zhu, John Toubia, Melissa R. Pitman, Craig T. Wallington-Beddoe, Paul A. B. Moretti, Diana Iarossi, Saumya E. Samaraweera, Nik Cummings, Hayley S. Ramshaw, Daniel Thomas, Andrew H. Wei, Angel F. Lopez, Richard J. D’Andrea, Ian D. Lewis, Stuart M. Pitson
Journal: Blood
Blood (2017) 129 (6): 771–782.
https://doi.org/10.1182/blood-2016-06-720433
Published: 2017
Includes: Supplemental data
Journal Articles

Metabolic Profiling of Adult Acute Myeloid Leukemia (AML)

Mahmoud A Bassal, Bsc, BCompSc, Paul Leo, PhD, Saumya E Samaraweera, PhD, Kyaw Ze Ya Maung, BSc, Milena Babic, Parvathy Venugopal, BSc, Jesse Cheah, BSc, Christopher N Hahn, PhD, Hamish S Scott, BSc, PhD FFSc (RCPA), Evgeny Glazov, PhD, Sarah C Bray, PhD, Diana Iarossi, Ing Soo Tiong, MBChB, Mhairi Clout, MSc, Emma Duncan, PhD, L. Bik To, MD, Paula Marlton, MBBS, FRACP, FRCPA, Ian D Lewis, MBBS, PhD FRACP, FRCPA, Devinder S Gill, MBChB FRCPath MRCP, Thomas J Gonda, PhD, Anna L Brown, PhD, Richard D'Andrea, PhD
Journal: Blood
Blood (2016) 128 (22): 1684.
https://doi.org/10.1182/blood.V128.22.1684.1684
Published: 2016
Journal Articles

Hypermethylation of GADD45A Defines a Methylation Profile Distinct to Mutant IDH1/2 , and Correlates with More Aggressive AML

Saumya E Samaraweera, PhD, Francine E. Garrett-Bakelman, MD PhD, Yaseswini Neelamraju, Michelle Perugini, PhD, Debora A. Casolari, PhD, Diana Iarossi, Sarah C Bray, PhD, Caroline Sheridan, Tak C Lee, M.S., Ing Soo Tiong, MBChB, Silke Danner, Nik Cummings, BSc, Monica L. Guzman, PhD, Gail J. Roboz, Luen Bik To, MBBS, FRACP, FRCPA, PhD, Andrew Wei, Christopher E. Mason, PhD, Christopher Y. Park, MD PhD, Ross L. Levine, MD, Martin Carroll, MD, Michael W. Becker, MD, Ian D Lewis, MBBS, PhD FRACP, FRCPA, Ari Melnick, MD, Richard D'Andrea, PhD
Journal: Blood
Blood (2016) 128 (22): 2877.
https://doi.org/10.1182/blood.V128.22.2877.2877
Published: 2016
Journal Articles

The Significance of GADD45A Promoter DNA Hypermethylation in AML: Association with IDH1/2 and TET2 Mutation

Michelle Perugini, PhD, Saumya E Samaraweera, PhD, Anna L Brown, PhD, Nik Cummings, BSc, Silke Danner, Ing Soo Tiong, MBChB, Francine E Garrett-Bakelman, MD PhD, Martin P. Carroll, MD, Michael W. Becker, MD, Stephen S. Chung, MD, Christopher Y. Park, MD PhD, Christopher E Mason, PhD, Monica L. Guzman, PhD, Ross L. Levine, MD, Ari M Melnick, MD, Luen Bik To, MBBS, PhD, Andrew H Wei, MBBS, PhD, Ian D Lewis, MBBS, PhD, Richard J D'Andrea, PhD
Journal: Blood
Blood (2014) 124 (21): 69.
https://doi.org/10.1182/blood.V124.21.69.69
Published: 2014