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Journal Articles

Loss of the stress sensor GADD45A promotes stem cell activity and ferroptosis resistance in LGR4/HOXA9-dependent AML

Blood (2024) 144 (1): 84–98.

https://doi.org/10.1182/blood.2024024072

Published: 2024

Includes: Supplemental data

Journal Articles

The ERK2-DBP domain opposes pathogenesis of a mouse JAK2V617F-driven myeloproliferative neoplasm

Yong Zhang, Billy Truong, Shawn P. Fahl, Esteban Martinez, Kathy Q. Cai, Essel D. Al-Saleem, Yulan Gong, Dan A. Liebermann, Jonathan Soboloff, Roland Dunbrack, Ross L. Levine, Steven Fletcher, Dietmar Kappes, Stephen M. Sykes, Paul Shapiro, David L. Wiest

Blood (2022) 140 (4): 359–373.

https://doi.org/10.1182/blood.2021013068

Published: 2022

Includes: Supplemental data

Journal Articles

Gadd45 Null Mice and Neutrophils/Macrophages Derived From the Bone Marrow of These Mice Exhibit Impaired Innate-Immune/Inflammatory Reponses.

Dominic M Salerno, Barbara Hoffman, PhD, Dan A. Liebermann, PhD

Blood (2009) 114 (22): 1350.

https://doi.org/10.1182/blood.V114.22.1350.1350

Published: 2009

Journal Articles

Stress Response Gadd45a Gene as Tumor Suppressor in MYC Expressing Myeloid Cells Is Cytokine Specific.

Alisha A Mohamed-Hadley, B.S., Dan A. Liebermann, PhD, Barbara Hoffman, PhD

Blood (2009) 114 (22): 1481.

https://doi.org/10.1182/blood.V114.22.1481.1481

Published: 2009

Journal Articles

Loss of Growth Arrest DNA Damage 45a,b (GADD45a,b) Enhances Oncogenicity in BCR/ABL-Driven Chronic Myelogenous Leukemia.

Xiaojin Sha, PhD, MD, Dan A. Liebermann, PhD, Barbara Hoffman, PhD

Blood (2009) 114 (22): 3264.

https://doi.org/10.1182/blood.V114.22.3264.3264

Published: 2009

Journal Articles

Loss of Growth Arrest DNA Damage 45b (GADD45b) Enhances Oncogenicity in BCR/ABL-Induced Chronic Myelogenous Leukemia

Xiaojin Sha, PhD, MD, Barbara Hoffman, PhD, Dan A. Liebermann, PhD

Blood (2008) 112 (11): 5337.

https://doi.org/10.1182/blood.V112.11.5337.5337

Published: 2008

Journal Articles

Gadd45 Genes Participate in Myeloid Cell Fate Determination.

John D. Gibbs, PhD, Alisha Mohamed-Hadley, BS, Dan A. Liebermann, PhD, Barbara Hoffman, PhD

Blood (2007) 110 (11): 4043.

https://doi.org/10.1182/blood.V110.11.4043.4043

Published: 2007

Journal Articles

Gadd45a Behaves as a Tumor Suppressor and Gadd45b Behaves as an Oncogene in myc-Mediated Block in Myeloid Differentiation.

Alisha Mohamed-Hadley, BS, John D. Gibbs, PhD, Dan A. Liebermann, PhD, Barbara Hoffman, PhD

Blood (2007) 110 (11): 4163.

https://doi.org/10.1182/blood.V110.11.4163.4163

Published: 2007

Journal Articles

Egr-1 Functions as a Tumor Suppressor for Leukemias Caused by Different Oncogenes.

John D. Gibbs, BS, Dan A. Liebermann, Ph.D., Barbara Hoffman, Ph.D.

Blood (2006) 108 (11): 1450.

https://doi.org/10.1182/blood.V108.11.1450.1450

Published: 2006

Journal Articles

Egr-1 abrogates the block imparted by c-Myc on terminal M1 myeloid differentiation

Marianna Shafarenko, Dan A. Liebermann, Barbara Hoffman

Blood (2005) 106 (3): 871–878.

https://doi.org/10.1182/blood-2004-08-3056

Published: 2005

Journal Articles

Gadd45a and Gadd45b Protect Haematopoetic Cells from Ultraviolet Radiation Induced Apoptosis Via Distinct Signaling Pathways.

Mamta Gupta, Ph.D, Shiv K. Gupta, Ph.D, Barbara Hoffman, Ph.D, Dan A. Liebermann, Ph.D

Blood (2004) 104 (11): 1258.

https://doi.org/10.1182/blood.V104.11.1258.1258

Published: 2004

Journal Articles

Egr-1 Abrogates the Block Imparted by c-Myc on Terminal M1 Myeloid Differentiation.

Barbara Hoffman, PhD, Marianna Shafarenko, PhD, Dan A. Liebermann, PhD

Blood (2004) 104 (11): 2579.

https://doi.org/10.1182/blood.V104.11.2579.2579

Published: 2004

Journal Articles

IL6 Protection of Myeloid Leukemic Cells Against P53 Induced Apoptosis Is Mediated by Activation of P13kinase/AKT and Stabilization of C-FLIP.

Diana L. Vesely, BA, Barbara Hoffman, PhD, Dan A. Liebermann, PhD

Blood (2004) 104 (11): 1271.

https://doi.org/10.1182/blood.V104.11.1271.1271

Published: 2004

Journal Articles

Challenging E2F-1 and c-Myb Block of Myeloid Terminal Differentiation with the Tumor Suppressor-Egr1.

John D. Gibbs, B.S, Alaina A. Borden, B.S, Dan A. Liebermann, Ph.D, Barbara Hoffman, Ph.D.

Blood (2004) 104 (11): 4330.

https://doi.org/10.1182/blood.V104.11.4330.4330

Published: 2004

Journal Articles

The Addition of the Estrogen Receptor to the Carboxy Terminus of c-Myc Inhibits the Fas/CD-95 Apoptotic Pathway Associated with the Myc-Mediated Block in Myeloid Differentiation.

Santo A. D’Angelo, MS, Dan A. Liebermann, PhD, Barbara Hoffman, PhD.

Blood (2004) 104 (11): 4346.

https://doi.org/10.1182/blood.V104.11.4346.4346

Published: 2004

Journal Articles

Hematopoietic Cells from Gadd45a, Gadd45b Deficent Mice Exhibit Altered Myelopoiesis and Higher Apoptosis after Cytokine Treatment.

Shiv K. Gupta, Ph.D., Mamta Gupta, Ph.D., Barbara Hoffman, Ph.D., Dan A. Liebermann, Ph.D.

Blood (2004) 104 (11): 1697.

https://doi.org/10.1182/blood.V104.11.1697.1697

Published: 2004

Journal Articles

Fos modulates myeloid cell survival and differentiation and partially abrogates the c-Myc block in terminal myeloid differentiation

Marianna Shafarenko, Arshad Amanullah, Bernard Gregory, Dan A. Liebermann, Barbara Hoffman

Blood (2004) 103 (11): 4259–4267.

https://doi.org/10.1182/blood-2002-09-2704

Published: 2004

Journal Articles

Activation of the Jak3 pathway is associated with granulocytic differentiation of myeloid precursor cells

Sushil G. Rane, James K. Mangan, Arshad Amanullah, Brian C. Wong, Renu K. Vora, Dan A. Liebermann, Barbara Hoffman, Xavier Graña, E. Premkumar Reddy

Blood (2002) 100 (8): 2753–2762.

https://doi.org/10.1182/blood.V100.8.2753

Published: 2002

Journal Articles

Transcriptional regulation of myeloid differentiation primary response (MyD) genes during myeloid differentiation is mediated by nuclear factor Y

Robert M. Tjin Tham Sjin, Kandasamy Krishnaraju, Barbara Hoffman, Dan A. Liebermann

Blood (2002) 100 (1): 80–88.

https://doi.org/10.1182/blood.V100.1.80

Published: 2002

Journal Articles

Early growth response gene 1 stimulates development of hematopoietic progenitor cells along the macrophage lineage at the expense of the granulocyte and erythroid lineages

Kandasamy Krishnaraju, Barbara Hoffman, Dan A. Liebermann

Blood (2001) 97 (5): 1298–1305.

https://doi.org/10.1182/blood.V97.5.1298

Published: 2001

NARROW

Loss of the stress sensor GADD45A promotes stem cell activity and ferroptosis resistance in LGR4/HOXA9-dependent AML

The ERK2-DBP domain opposes pathogenesis of a mouse JAK2V617F-driven myeloproliferative neoplasm

Gadd45 Null Mice and Neutrophils/Macrophages Derived From the Bone Marrow of These Mice Exhibit Impaired Innate-Immune/Inflammatory Reponses.

Stress Response Gadd45a Gene as Tumor Suppressor in MYC Expressing Myeloid Cells Is Cytokine Specific.

Loss of Growth Arrest DNA Damage 45a,b (GADD45a,b) Enhances Oncogenicity in BCR/ABL-Driven Chronic Myelogenous Leukemia.

Loss of Growth Arrest DNA Damage 45b (GADD45b) Enhances Oncogenicity in BCR/ABL-Induced Chronic Myelogenous Leukemia

Gadd45 Genes Participate in Myeloid Cell Fate Determination.

Gadd45a Behaves as a Tumor Suppressor and Gadd45b Behaves as an Oncogene in myc-Mediated Block in Myeloid Differentiation.

Egr-1 Functions as a Tumor Suppressor for Leukemias Caused by Different Oncogenes.

Egr-1 abrogates the block imparted by c-Myc on terminal M1 myeloid differentiation

Gadd45a and Gadd45b Protect Haematopoetic Cells from Ultraviolet Radiation Induced Apoptosis Via Distinct Signaling Pathways.

Egr-1 Abrogates the Block Imparted by c-Myc on Terminal M1 Myeloid Differentiation.

IL6 Protection of Myeloid Leukemic Cells Against P53 Induced Apoptosis Is Mediated by Activation of P13kinase/AKT and Stabilization of C-FLIP.

Challenging E2F-1 and c-Myb Block of Myeloid Terminal Differentiation with the Tumor Suppressor-Egr1.

The Addition of the Estrogen Receptor to the Carboxy Terminus of c-Myc Inhibits the Fas/CD-95 Apoptotic Pathway Associated with the Myc-Mediated Block in Myeloid Differentiation.

Hematopoietic Cells from Gadd45a, Gadd45b Deficent Mice Exhibit Altered Myelopoiesis and Higher Apoptosis after Cytokine Treatment.

Fos modulates myeloid cell survival and differentiation and partially abrogates the c-Myc block in terminal myeloid differentiation

Activation of the Jak3 pathway is associated with granulocytic differentiation of myeloid precursor cells

Transcriptional regulation of myeloid differentiation primary response (MyD) genes during myeloid differentiation is mediated by nuclear factor Y

Early growth response gene 1 stimulates development of hematopoietic progenitor cells along the macrophage lineage at the expense of the granulocyte and erythroid lineages

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American Society of Hematology

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American Society of Hematology

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