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Journal Articles

ERK2 Substrate Binding Domains Play Distinct Roles in Megakaryocytic-Erythroid Lineage Progression and Mediates Clonal Fitness in Myeloproliferative Neoplasms

Billy Truong, Yong Zhang, Esteban Martinez, Brianna Trankle, Anna-Mariya Kukuyan, Susan Shinton, James Oesterling, Xiang Hua, Dietmar J Kappes, Joan Font-Burgada, Tomasz Skorski, David Wiest

Blood (2022) 140 (Supplement 1): 6733–6734.

https://doi.org/10.1182/blood-2022-170264

Published: 2022

Journal Articles

Fatty Acid Desaturation Is a Metabolic Vulnerability of Acute Myeloid Leukemia Cells

Joice Kanefsky, Yorrick Jaspers, Esteban Martinez, Jacklyn Huhn, Daniela Di Marcoantonio, Stephan Kemp, David Wiest, Stephen M. Sykes

Blood (2022) 140 (Supplement 1): 5885–5886.

https://doi.org/10.1182/blood-2022-170721

Published: 2022

Journal Articles

Identification of ATF4 As a Key Upstream Regulator of Acute Myeloid Leukemia Cell Metabolism

Jacklyn Huhn, Esteban Martinez, Joice Kanefsky, Aaron Goldman, Simone Sidoli, David Wiest, Stephen M. Sykes

Blood (2022) 140 (Supplement 1): 11838.

https://doi.org/10.1182/blood-2022-170467

Published: 2022

Journal Articles

Acute Myeloid Leukemia Cells Rely on the Glycolytic Enzyme PGK1 to Support Energy Production and Amino Acid Metabolism

Liana Valin, Joice Kanefsky, Esteban Martinez, Jacklyn Huhn, Orsola Di Martino, Stephen M. Sykes, Judith Sokei

Blood (2022) 140 (Supplement 1): 8694–8695.

https://doi.org/10.1182/blood-2022-166659

Published: 2022

Journal Articles

The ERK2-DBP domain opposes pathogenesis of a mouse JAK2V617F-driven myeloproliferative neoplasm

Yong Zhang, Billy Truong, Shawn P. Fahl, Esteban Martinez, Kathy Q. Cai, Essel D. Al-Saleem, Yulan Gong, Dan A. Liebermann, Jonathan Soboloff, Roland Dunbrack, Ross L. Levine, Steven Fletcher, Dietmar Kappes, Stephen M. Sykes, Paul Shapiro, David L. Wiest

Blood (2022) 140 (4): 359–373.

https://doi.org/10.1182/blood.2021013068

Published: 2022

Includes: Supplemental data

Journal Articles

ERK2 Substrate Binding Domains Perform Opposing Roles in Pathogenesis of a JAK2V617F-Driven Myeloproliferative Neoplasm

Billy Truong, Yong Zhang, Shawn Fahl, Kathy Q Cai, Esteban Martinez, Essel D. Al-Saleem, Yulan Gong, Dan Liebermann, Jonathan Soboloff, Roland Dunbrack, Ross L. Levine, Dietmar J Kappes, Stephen M. Sykes, Paul Shapiro, David Wiest

Blood (2021) 138 (Supplement 1): 2547.

https://doi.org/10.1182/blood-2021-152063

Published: 2021

Journal Articles

Pkcε Is a Central Regulator of Mitochondrial Function and Metabolism in Acute Myeloid Leukemia

Daniela Di Marcantonio, PhD, Elena Masselli, MD, Esteban Martinez, BS, Daniela Araiza-Olivera, MD PhD, Giuliana Gobbi, PhD, Prisco Mirandola, PhD, Marco Vitale, MD, Stephen M. Sykes, PhD

Blood (2018) 132 (Supplement 1): 3926.

https://doi.org/10.1182/blood-2018-99-119758

Published: 2018

Journal Articles

JUN and ATF3 Regulate the Transcriptional Output of the Unfolded Protein Response to Support Acute Myeloid Leukemia

Stephen M. Sykes, PhD, Daniela Di Marcantonio, PhD, Esteban Martinez, BS, Jacqueline Huhn, BS, Anushk Gupta, Ritika Mistry

Blood (2018) 132 (Supplement 1): 1327.

https://doi.org/10.1182/blood-2018-99-119742

Published: 2018

Journal Articles

Foxos Suppress Lipid Peroxidation to Promote AML Progression and Chemotherapy Resistance

Turan Aghayev, Chun Zhou, PhD, Alyssa Klein, Esteban Martinez, Claudia Scholl, Stefan Fröhling, Stephen Matthew Sykes, PhD

Blood (2015) 126 (23): 1861.

https://doi.org/10.1182/blood.V126.23.1861.1861

Published: 2015

Journal Articles

C-Jun Regulates ER Stress Signaling to Promote Chemotherapy Resistance in Acute Myeloid Leukemia

Chun Zhou, PhD, Daniela Di Marcantonio, PhD, Esteban Martinez, Nehal Solanki-Patel, Suraj Peri, PhD, Claudia Scholl, Stefan Fröhling, David L. Wiest, PhD, Stephen Matthew Sykes, PhD

Blood (2015) 126 (23): 2464.

https://doi.org/10.1182/blood.V126.23.2464.2464

Published: 2015

Journal Articles

Pkc Epsilon Regulates Mitochondrial Redox Biology to Support the Differentiation Blockade in Acute Myeloid Leukemia

Daniela Di Marcantonio, PhD, Jessica Vadaketh, Esteban Martinez, Prisco Mirandola, PhD, Giuliana Gobbi, PhD, Michael D. Milsom, PhD, Claudia Scholl, Stefan Fröhling, Marco Vitale, MD, Stephen Matthew Sykes, PhD

Blood (2015) 126 (23): 444.

https://doi.org/10.1182/blood.V126.23.444.444

Published: 2015

NARROW

ERK2 Substrate Binding Domains Play Distinct Roles in Megakaryocytic-Erythroid Lineage Progression and Mediates Clonal Fitness in Myeloproliferative Neoplasms

Fatty Acid Desaturation Is a Metabolic Vulnerability of Acute Myeloid Leukemia Cells

Identification of ATF4 As a Key Upstream Regulator of Acute Myeloid Leukemia Cell Metabolism

Acute Myeloid Leukemia Cells Rely on the Glycolytic Enzyme PGK1 to Support Energy Production and Amino Acid Metabolism

The ERK2-DBP domain opposes pathogenesis of a mouse JAK2V617F-driven myeloproliferative neoplasm

ERK2 Substrate Binding Domains Perform Opposing Roles in Pathogenesis of a JAK2V617F-Driven Myeloproliferative Neoplasm

Pkcε Is a Central Regulator of Mitochondrial Function and Metabolism in Acute Myeloid Leukemia

JUN and ATF3 Regulate the Transcriptional Output of the Unfolded Protein Response to Support Acute Myeloid Leukemia

Foxos Suppress Lipid Peroxidation to Promote AML Progression and Chemotherapy Resistance

C-Jun Regulates ER Stress Signaling to Promote Chemotherapy Resistance in Acute Myeloid Leukemia

Pkc Epsilon Regulates Mitochondrial Redox Biology to Support the Differentiation Blockade in Acute Myeloid Leukemia

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American Society of Hematology

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ASH Publications

American Society of Hematology

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