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Joachim R. Goethert
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Journal Articles

Firstline Treatment with Ruxolitinib Versus Best Available Therapy in Patients with Polycythemia Vera: Pre-Specified Interim Analysis of the Randomized Phase 2b Ruxobeat Clinical Trial of the German Study Group for Myeloproliferative Neoplasms (GSG-MPN)

Steffen Koschmieder, Susanne Isfort, Lino L. Teichmann, Philippe Schafhausen, Florian Heidel, Andreas Hochhaus, Martin Griesshammer, Katja Sockel, Philipp Jost, Denise Wolleschak, Konstanze Döhner, Joachim R. Goethert, Markus P. Radsak, Marinela Augustin, Heiko Becker, Aristoteles Giagounidis, Markus Schaich, Martine Klausmann, Nikolas Von Bubnoff, Frank Stegelmann, Maike Kortmann, Julia Frank, Martin Hellmich, Tim H. Brümmendorf
Journal: Blood
Blood (2023) 142 (Supplement 1): 619.
https://doi.org/10.1182/blood-2023-173225
Published: 2023
Journal Articles

Bomedemstat (IMG-7289), an LSD1 Inhibitor, Manages the Signs and Symptoms of Essential Thrombocythemia (ET) While Reducing the Burden of Cells Homozygous for Driver Mutations

Joachim R. Goethert, Harinder Gill, Francesca Palandri, David M. Ross, Tara Cochrane, Stephen R. Larsen, Anna B. Halpern, Jake Shortt, James M. Rossetti, James Liang, Monia Marchetti, Andrew J. Wilson, Andrew Innes, Merit Hanna, William S. Stevenson, Alessandro M. Vannucchi, Maria Kleppe, Georges Natsoulis, Claire N Harrison, Hugh Young Rienhoff Jr.
Journal: Blood
Blood (2023) 142 (Supplement 1): 747.
https://doi.org/10.1182/blood-2023-179329
Published: 2023
Journal Articles

Genomic Landscape and Molecular Risk in Patients with Advanced Myelofibrosis Treated within the Multicenter Phase Ib/II MPNSG0212 (POMINC) Trial

Ekaterina Panina, Steffen Koschmieder, Florian H. Heidel, Andreas Hochhaus, Holger Hebart, Susanne Isfort, Frank G. Rücker, Andreas Reiter, Markus Bangerter, Cornelius Waller, Christoph Scheid, Denise Wolleschak, Joachim R. Goethert, Philippe Schafhausen, Thomas Kindler, Markus P. Radsak, Norbert Gattermann, Robert Möhle, Nikolas von Bubnoff, Tim H Brümmendorf, Hartmut Döhner, Martin Griesshammer, Frank Stegelmann, Konstanze Döhner
Journal: Blood
Blood (2021) 138 (Supplement 1): 4637.
https://doi.org/10.1182/blood-2021-150361
Published: 2021
Journal Articles

AML Associated Mesenchymal Stroma Cells Support Growth of AML Cells As a Result of Activated Notch Signaling and This Can be Targeted By Dexamethasone

Helal Mohammed Mohammed Ahmed Ahmed, MBBS, Yahya Saleh Al-Matary, PhD, Subbaiah Chary Nimmagadda, PhD, Maren Fiori, Pradeep Kumar Patnana, M.Sc., Daria Frank, Lanying Wei, M.Sc., Judith Schütte, PhD, Tobias May, Joachim R. Goethert, MD, Thomas Schroeder, MD, Ulrike Buttkereit, PhD, Christian Recher, MD PhD, Manuel Rodríguez-Paredes, Thorsten Koenig, Wolfgang Hartmann, MD, Jan Tuckermann, PhD, Bertram Opalka, PhD, Georg Lenz, Cyrus Khandanpour, PD, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 1.
https://doi.org/10.1182/blood-2020-134177
Published: 2020
Journal Articles

Comorbidities Such As Thromboembolic Events Significantly Worsen Patient-Reported Quality of Life (QoL) and Symptoms in Myeloproliferative Neoplasms (MPN) - Data from the Bioregistry of the German Study Group for MPN (GSG-MPN)

Susanne Isfort, Frank Stegelmann, MD, Martine Klausmann, MD, Holger Schulz, Wiebke Hollburg, MD, Haifa Kathrin Al-Ali, Joachim R. Goethert, MD, Florian H. Heidel, MD, Christoph Maintz, MD, Mathias Haenel, MD, Uwe Platzbecker, Richard Hansen, MD, Andras Keszei, MD, Judith Gecht, Kim Kricheldorf, Andrea Kaifie, MD, Martina Crysandt, Deniz Gezer, MD, Martin Griesshammer, MD PhD, Tim H Brümmendorf, MD, Konstanze Döhner, MD, Steffen Koschmieder, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4292.
https://doi.org/10.1182/blood-2018-99-112377
Published: 2018
Journal Articles

Chuvash Polycythemia Patients from Afghanistan and Southern India Share a Common VHL Gene Haplotype. Support for Its Origin before Asians and Europeans Diverged

Christine Min, Jihyun Song, PhD, Joachim R. Goethert, MD, Soo Jin Kim, MS, Victor R. Gordeuk, MD, Josef T. Prchal, MD, Alan Lubin, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 930.
https://doi.org/10.1182/blood.V130.Suppl_1.930.930
Published: 2017
Journal Articles

Nuclear NFATc1 Causes Development of Fms-like Receptor Tyrosine Kinase 3 Receptor (FLT3) Internal Tandem Duplication Mutation-Positive (FLT3-ITD) Acute Myeloid Leukemia (AML) and Mediates Drug Resistance

Maria A. Solovey, Ying Wang, MD, Stefan Gattenloehner, MD, Elisabeth Hessmann, MD, Stephan Metzelder, MD, Christian Michel, MD, Volker Ellenrieder, MD, Joachim R. Goethert, MD, Andreas Neubauer, Andreas Burchert, MD
Journal: Blood
Blood (2016) 128 (22): 1722.
https://doi.org/10.1182/blood.V128.22.1722.1722
Published: 2016
Journal Articles

Diagnosis and Treatment of Myeloproliferative Neoplasms in Germany: First Results from the SAL-MPN Registry

Andrea Kaifie, MD, Susanne Isfort, MD, Dominik Wolf, MD, Mathias Hanel, MD, Christoph Maintz, MD, Norbert Gattermann, MD PhD, Uwe Platzbecker, MD, Eray Goekkurt, MD, Ina Boeters, MD, Richard Hansen, MD, Fabian Lang, MD, Joachim R. Goethert, Karla Bennemann, MD, Christoph Rollig, MD MSC, Hubert Serve, MD, Wolfgang E Berdel, MD, Gerhard Ehninger, MD, Tim H Bruemmendorf, MD, Steffen Koschmieder, MD
Journal: Blood
Blood (2014) 124 (21): 5561.
https://doi.org/10.1182/blood.V124.21.5561.5561
Published: 2014
Journal Articles

Heterogeneous Interactions of Leukemic and Control Bone Marrow Stroma Cells with an AML Cell Line and AML Leukemic Blasts.

Ulrike Buttkereit, Sana Mohamad, Monika Lindemann, Joachim R. Goethert, Bertram Opalka, Jan Duerig, Ulrich Duehrsen
Journal: Blood
Blood (2010) 116 (21): 1047.
https://doi.org/10.1182/blood.V116.21.1047.1047
Published: 2010