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Journal Articles

Tumor-Infiltrating Normal B Lymphocytes Have Remarkable Prognostic Effects and Are Crucial for Antitumor Immune Responses in Diffuse Large B-Cell Lymphoma

Zijun Y. Xu-Monette, Yong Li, Thomas Snyder, Tiantian Yu, Tingxun LU, Alexandar Tzankov, Carlo Visco, Govind Bhagat, Wenbin Qian, Karen Dybkaer, April Chiu, Wayne Tam, Youli Zu, Eric D. Hsi, Frederick Hagemeister, Heounjeong Go, Maurilio Ponzoni, Andrés José María Ferreri, Michael Møller, Benjamin M. Parsons, Joannes H.J.M. Van Krieken, Yingjun Wang, Miguel Angel Piris, Jane Winter, Qingyan Au, Ilan Kirsch, Mingzhi Zhang, John D Shaughnessy, Jr, Bing Xu, Ken H. Young
Journal: Blood
Blood (2023) 142 (Supplement 1): 429.
https://doi.org/10.1182/blood-2023-179972
Published: 2023
Journal Articles

Diffuse Large B-Cell Lymphoma Has a Low Frequency of dMMR and High Frequencies of DNA Mismatch Repair Protein High Expression Associated with Lower T-Cell Infiltration

Zijun Y. Xu-Monette, Li Yu, Cancan Luo, Yong Li, Govind Bhagat, Alexandar Tzankov, Carlo Visco, Xiangshan Fan, Xiaosheng Fang, Karen Dybkaer, Ali Sakhdari, April Chiu, Wayne Tam, Youli Zu, Eric D. Hsi, F. B. Hagemeister, Dennis O'Malley, Qingyan Au, Harry Nunns, Heounjeong Go, Maurilio Ponzoni, Andrés José María Ferreri, Michael Møller, Benjamin M. Parsons, Joannes H.J.M. Van Krieken, Miguel Piris, Jane Winter, Bing Xu, Mingzhi Zhang, Ken H. Young
Journal: Blood
Blood (2023) 142 (Supplement 1): 6079.
https://doi.org/10.1182/blood-2023-178366
Published: 2023
Journal Articles

Research on Different Compound Combinations of Realgar-Indigo Naturalis Formula to Reverse APL Arsenic Resistance By Regulating Autophagy through mTOR Pathway

Ruibai Li, Yiming Pan, Chengyuan Xue, Guangda Li, Jieya Wu, Jingfang Zhang, Yayue Zhang, Jing Wang, Xinyi Chen, Ken H. Young, Li Hou
Journal: Blood
Blood (2023) 142 (Supplement 1): 5960.
https://doi.org/10.1182/blood-2023-181340
Published: 2023
Journal Articles

Chidamide Maintenance Therapy after Induction or Salvage Treatment in Patients with Peripheral T-Cell Lymphoma Ineligible for Autologous Stem Cell Transplantation

Wei Guo, Yangzhi Zhao, Xingtong Wang, Jia Li, Qiang Guo, Junna Li, Ken H. Young, Ou Bai
Journal: Blood
Blood (2021) 138 (Supplement 1): 2442.
https://doi.org/10.1182/blood-2021-152164
Published: 2021
Journal Articles

Determining Clinical Course of Diffuse Large B-Cell Lymphoma Using Targeted Transcriptome and Machine Learning Algorithms

Maher Albitar, Hong Zhang, Andre H. Goy, Zijun Xu-Monette, Govind Bhagat, Carlo Visco, Alexandar Tzankov, Xiaosheng Fang, Feng Zhu, Karen Dybkaer, April Chiu, Wayne Tam, Youli Zu, Eric D. Hsi, F. B. Hagemeister, Jooryung Huh, Maurilio Ponzoni, Andrés J M Ferreri, Michael Moller, Benjamin M Parsons, Joannes H.J.M. Van Krieken, Miguel Angel Piris, Jane N. Winter, Yong Li, Bing Xu, Ken H. Young
Journal: Blood
Blood (2021) 138 (Supplement 1): 2395.
https://doi.org/10.1182/blood-2021-148841
Published: 2021
Journal Articles

The Short-Term Efficacy and Safety of Brentuximab Vedotin Plus Cyclophosphamide, Epirubicin and Prednisone Acetate in Peripheral T Cell Lymphomas: A Real-World, Retrospective Case Series from China

Wei Guo, Xiaomeng Feng, Yinping Wang, Jia Li, Yangzhi Zhao, Limei Qu, Xu Yan, Junna Li, Qiang Guo, Ken H. Young, Ou Bai
Journal: Blood
Blood (2021) 138 (Supplement 1): 4563.
https://doi.org/10.1182/blood-2021-147695
Published: 2021
Journal Articles

A composite single-nucleotide polymorphism prediction signature for extranodal natural killer/T-cell lymphoma

Clinical Trials & Observations
Xiao-Peng Tian, Shu-Yun Ma, Ken H. Young, Choon Kiat Ong, Yan-Hui Liu, Zhi-Hua Li, Qiong-Li Zhai, Hui-Qiang Huang, Tong-Yu Lin, Zhi-Ming Li, Zhong-Jun Xia, Li-Ye Zhong, Hui-Lan Rao, Mei Li, Jun Cai, Yu-Chen Zhang, Fen Zhang, Ning Su, Peng-Fei Li, Feng Zhu, Zijun Y. Xu-Monette, Esther Kam Yin Wong, Jeslin Chian Hung Ha, Lay Poh Khoo, Le Ai, Run-Fen Cheng, Jing Quan Lim, Sanjay de Mel, Siok-Bian Ng, Soon Thye Lim, Qing-Qing Cai
Journal: Blood
Blood (2021) 138 (6): 452–463.
https://doi.org/10.1182/blood.2020010637
Published: 2021
Includes: Supplemental data
Journal Articles

MYD88 L265P elicits mutation-specific ubiquitination to drive NF-κB activation and lymphomagenesis

Xinfang Yu, Wei Li, Qipan Deng, Haidan Liu, Xu Wang, Hui Hu, Ya Cao, Zijun Y. Xu-Monette, Ling Li, Mingzhi Zhang, Zhongxin Lu, Ken H. Young, Yong Li
Journal: Blood
Blood (2021) 137 (12): 1615–1627.
https://doi.org/10.1182/blood.2020004918
Published: 2021
Includes: Supplemental data
Journal Articles

Fotemustine-Based in Combination with Rituximab As First-Line Induction Chemotherapy for Newly Diagnosed Primary Central Nervous System Lymphoma:a Prospective Phaseii Trial

Jingjing Wu, Fenghua Gao, Lei Zhang, Xin Li, Ling Li, Xinhua Wang, Linan Zhu, Xudong Zhang, Xiaorui Fu, Zhenchang Sun, MD, PhD, Meng Dong, Mengjie Ding, Hui Yu, Feifei Nan, Jiaqin Yan, Yu Chang, Xiaolong Wu, Zhiyuan Zhou, Mingzhi Zhang, MD, Ken H. Young
Journal: Blood
Blood (2020) 136 (Supplement 1): 5.
https://doi.org/10.1182/blood-2020-137449
Published: 2020
Journal Articles

Autologous Vs. Allogeneic Stem Cell Transplantation in Double-Expressor Lymphoma

Issa F. Khouri, MD, Stephen K. Gruschkus, PhD MPH, Celina Ledesma, Paolo Anderlini, Qaiser Bashir, May Daher, Swami P. Iyer, MD, David Marin, Rohtesh Mehta, Amanda L. Olson, Uday R. Popat, MD, Felipe Samaniego, MD, Muzaffar H. Qazilbash, MD, Jin S. Im, Gabriela Rondon, Richard E. Champlin, MD, Alison Gulbis, Ken H. Young
Journal: Blood
Blood (2020) 136 (Supplement 1): 24–25.
https://doi.org/10.1182/blood-2020-138741
Published: 2020
Journal Articles

Activating NOTCH1 Mutations Alter T-ALL Chemosensitivity By PREX2-AKT Pathway

Hui Yu, MD, PhD, Yuxin DU, MD, M.S., Ji Xu, MD, PhD, Zhenchang Sun, MD, PhD, Xiaorui Fu, MD, PhD, Ken H. Young, MD, PhD, Mingzhi Zhang, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 46–47.
https://doi.org/10.1182/blood-2020-138665
Published: 2020
Journal Articles

Stemness Signature Defined By Logistic Regression Machine Learning and Artificial Intelligence Predicts Outcomes in Diffuse Large B-Cell Lymphoma

Xiao-jie Liang, Na Yao, Dan Liu, Hai-ying Chen, Xin Xu, Jing-Wen Wang, Ken H. Young, Liang Wang
Journal: Blood
Blood (2020) 136 (Supplement 1): 19–20.
https://doi.org/10.1182/blood-2020-141791
Published: 2020
Journal Articles

Efficacy and Survival in Newly Diagnosed Advanced Extranodal Natural Killer/T-Cell Lymphoma: A Randomized, Controlled, Multicenter and Open-Labled Study with Ddgp Regimen Versus SMILE Regimen

Xinhua Wang, MD PhD, Lei Zhang, Xiangli Liu, Xin Li, Ling Li, Xiaorui Fu, Zhenchang Sun, Jingjing Wu, Xudong Zhang, Jiaqin Yan, Yu Chang, Feifei Nan, Zhiyuan Zhou, Xiaolong Wu, Li Tian, Wencai Li, Hongwei Xue, Jinghua Wang, Liqun Zou, Liping Su, Yi Lu, Yanzhen Guo, Ken H. Young, Mingzhi Zhang
Journal: Blood
Blood (2019) 134 (Supplement_1): 463.
https://doi.org/10.1182/blood-2019-127811
Published: 2019
Journal Articles

Addition of Drug-Response Specific Micro-RNAs to the International Prognostic Index Improves Prognostic Stratification of GCB-DLBCL Patients Treated with R-CHOP

Karen Dybkær, PhD, Hanne Due, MSc, Rasmus Froberg Brøndum, PhD, Ken H. Young, MD PhD, Martin Bøgsted, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1623.
https://doi.org/10.1182/blood-2019-122351
Published: 2019
Journal Articles

Clinical Relevance of MYC/BCL2 and Cell of Origin in Patients with Relapsed Diffuse Large B-Cell Lymphoma Treated with Autologous Stem Cell Transplantation

Yingjun Wang, Ken H. Young, MD PhD, Denái R. Milton, Celina Ledesma, Elias Jabbour, MD, Zijun Yidan Xu-Monette, PhD, Jeffrey J. Molldrem, Paolo Anderlini, Amin M. Alousi, MD, Qaiser Bashir, MBBS, May Daher, MD, Luis E. Fayad, MD, Swaminathan P. Iyer, MD, Partow Kebriaei, MD, David Marin, MD, Rohtesh S. Mehta, MD, Amanda L. Olson, MD, Uday Popat, MD, Felipe Samaniego, MD, Jason R. Westin, MD, Muzaffar H. Qazilbash, MD, Jin S Im, MD PhD, Gabriela Rondon, MD, Alison Gulbis, Richard E. Champlin, MD, Issa F. Khouri, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2021.
https://doi.org/10.1182/blood-2019-126719
Published: 2019
Journal Articles

Smart Start: Rituximab, Lenalidomide, and Ibrutinib Alone and in Combination with Standard Chemotherapy for Patients with Newly Diagnosed Diffuse Large B-Cell Lymphoma: Final Phase II Results

Jason R. Westin, MD, Loretta J. Nastoupil, MD MSc, Luis Fayad, MD, Fredrick B. Hagemeister, MD, Yasuhiro Oki, MD, Francesco Turturro, MD, Sairah Ahmed, MD, Maria Alma Rodriguez, MD, Hun Ju Lee, Raphael Eric Steiner, MD, Ranjit Nair, MBBS,MD, Simrit Parmar, MBBS, Ken H. Young, Timothy J. McDonnell, MD PhD, Hubert Chuang, Michael R Green, PhD, Sattva S Neelapu, MD, Eric Davis, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1581.
https://doi.org/10.1182/blood-2019-128475
Published: 2019
Journal Articles

Higher Stability of Mutant mRNA As Compared to Wild-Type mRNA in Diffuse Large B-Cell Lymphoma

Maher Albitar, MD, Zijun Yidan Xu-Monette, PhD, Wanlong Ma, Yingjun Wang, Deng Manman, MD, Alexandar Tzankov, MD, Carlo Visco, Govind Bhagat, MD, Karen Dybkær, PhD, Ivan De Dios, BS, Wayne Tam, MD PhD, Eric D. Hsi, MD, Maurilio Ponzoni, MD, Andres JM Ferreri, MD, Michael Boe Møller, Miguel A. Piris, Joannes H.J.M. Van Krieken, PhDMD, Youli Zu, MD PhD, Hagop M. Kantarjian, MD, Yong Li, PhD, Ken H. Young
Journal: Blood
Blood (2019) 134 (Supplement_1): 1499.
https://doi.org/10.1182/blood-2019-128516
Published: 2019
Journal Articles

Efficacy and Safety of Apatinib in Relapsed or Refractory Diffuse Large B Cell Lymphoma: An Open-Label, Single-Arm, Prospective Study

Xinran Ma, MSc, Ling Li, Lei Zhang, Xin Li, Xiaorui Fu, Xinhua Wang, PhD, Jingjing Wu, Xudong Zhang, Xiaoyan Feng, Zhiyuan Zhou, Yu Chang, Zhaoming Li, MD PhD, Ken H. Young, Mingzhi Zhang
Journal: Blood
Blood (2019) 134 (Supplement_1): 2873.
https://doi.org/10.1182/blood-2019-127912
Published: 2019
Journal Articles

Cell of Origin Classification of DLBCL Using Targeted NGS Expression Profiling and Deep Learning

Maher Albitar, MD, Zijun Yidan Xu-Monette, PhD, Babak Shahbaba, PhD, Ivan De Dios, BS, Yingjun Wang, Deng Manman, MD, Alexandar Tzankov, MD, Carlo Visco, Govind Bhagat, MD, Karen Dybkær, PhD, Wayne Tam, MD PhD, Eric D. Hsi, MD, Maurilio Ponzoni, MD, Andres JM Ferreri, MD, Michael Moller, Miguel A. Piris, Joannes H.J.M. Van Krieken, PhDMD, Youli Zu, MD PhD, Wanlong Ma, Hagop M. Kantarjian, MD, Yong Li, PhD, Ken H. Young, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2891.
https://doi.org/10.1182/blood-2019-126927
Published: 2019
Journal Articles

Gene Expression Profiling Using Nanostring™ Reveals Differences According to Location, Histology and MIPI Score in Mantle Cell Lymphoma

Diana Lucia Martínez Baquero, MD, Ken H. Young, Roberto N. Miranda, MD, L. Jeffrey Medeiros, MD, Chi Young Ok, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5218.
https://doi.org/10.1182/blood-2019-132056
Published: 2019