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Zhi-Hua Li
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Journal Articles

A composite single-nucleotide polymorphism prediction signature for extranodal natural killer/T-cell lymphoma

Clinical Trials & Observations
Xiao-Peng Tian, Shu-Yun Ma, Ken H. Young, Choon Kiat Ong, Yan-Hui Liu, Zhi-Hua Li, Qiong-Li Zhai, Hui-Qiang Huang, Tong-Yu Lin, Zhi-Ming Li, Zhong-Jun Xia, Li-Ye Zhong, Hui-Lan Rao, Mei Li, Jun Cai, Yu-Chen Zhang, Fen Zhang, Ning Su, Peng-Fei Li, Feng Zhu, Zijun Y. Xu-Monette, Esther Kam Yin Wong, Jeslin Chian Hung Ha, Lay Poh Khoo, Le Ai, Run-Fen Cheng, Jing Quan Lim, Sanjay de Mel, Siok-Bian Ng, Soon Thye Lim, Qing-Qing Cai
Journal: Blood
Blood (2021) 138 (6): 452–463.
https://doi.org/10.1182/blood.2020010637
Published: 2021
Includes: Supplemental data
Journal Articles

Biomarker Driven Phase II Clinical Trial of Trametinib in Relapsed/Refractory Multiple Myeloma with Sequential Addition of the AKT Inhibitor, GSK2141795 at Time of Disease Progression to Overcome Treatment Failure: A Trial of the Princess Margaret Phase II Consortium

Suzanne Trudel, MD, Nizar J. Bahlis, MD, Christopher P. Venner, MD, Annette E Hay, MB ChB, Olena Kis, PhD, Signy Chow, MD FRCPC, Zhi Hua Li, MD, Ellen Nong Wei, MSc, Lisa Wang, PhD, Christine Tran, Smitha Udagani, Chantale Blattler, Trevor J. Pugh, PhD, Helen X Chen, MD, Amit Oza, MD
Journal: Blood
Blood (2016) 128 (22): 4526.
https://doi.org/10.1182/blood.V128.22.4526.4526
Published: 2016
Journal Articles

The Potent STAT3/5 Inhibitor, BP-1-102 Demonstrates Significant Anti-Tumor Activity Against Waldenström Macroglobulinemia

Danielle C Croucher, Victor H Jimenez-Zepeda, MD, PD, Zhi Hua Li, Ellen Wei, Brent DG Page, James Turkson, Patrick T Gunning, Suzanne Trudel, MD, MSC, FRCPC
Journal: Blood
Blood (2011) 118 (21): 5101.
https://doi.org/10.1182/blood.V118.21.5101.5101
Published: 2011
Journal Articles

Studies of BP-1-102, a Novel Direct Small-Molecule Inhibitor of Stat3 Demonstrates Substantial Anti-Myeloma Pre-Clinical Activity

Victor H Jimenez-Zepeda, MD, PD, Zhi Hua Li, Brent DG Page, Seda Zeng, Ellen Wei, Chungyee Leung-Hagesteijn, James Turkson, Patrick T. Gunning, Suzanne Trudel, MD, MSC, FRCPC
Journal: Blood
Blood (2010) 116 (21): 138.
https://doi.org/10.1182/blood.V116.21.138.138
Published: 2010
Journal Articles

Pre-Clinical Evaluation of a Small Molecule Inhibitor of CDK1 as Potential Therapy for MYC Expressing Mutiple Myeloma Tumors

Seda Zeng, Zhi Hua Li, MD, Marta Chesi, Chungyee Leung-Hagesteijn, MSc, Sheng-ben Liang, PhD, P. Leif Bergsagel, MD, Suzanne Trudel, MD
Journal: Blood
Blood (2008) 112 (11): 3667.
https://doi.org/10.1182/blood.V112.11.3667.3667
Published: 2008
Journal Articles

A Phase II Study of Lenalidomide in Previously Untreated, Symptomatic Chronic Lymphocytic Leukemia (CLL)

Christine Chen, MD, Harminder Paul, Wei Xu, PhD, Vishal Kukreti, Suzanne Trudel, Ellen Wei, Zhi Hua Li, Joseph Brandwein, Mariela Pantoja, Chungyee Leung-Hagensteijn
Journal: Blood
Blood (2008) 112 (11): 44.
https://doi.org/10.1182/blood.V112.11.44.44
Published: 2008
Journal Articles

Potentiated Phospho-Protein Network Profiling of Multiple Myeloma Cell Lines and Primary Patient Samples by Multi-Parameter Flow Cytometry.

Zhi Hua Li, MD, Peter Leif Bergsagel, MD, Sue Chow, David Hedley, MD, Suzanne Trudel, MD
Journal: Blood
Blood (2007) 110 (11): 1505.
https://doi.org/10.1182/blood.V110.11.1505.1505
Published: 2007
Journal Articles

Evaluation of XL999, a Potent Inhibitor of FGFR3, for the Potential Treatment of t(4;14) Positive Multiple Myeloma.

Suzanne Trudel, MD, Xiu Zhi Yang, MD, Zhi Hua Li, MD, Sheng-ben Liang, PhD, Dana T. Aftab, PhD
Journal: Blood
Blood (2007) 110 (11): 2515.
https://doi.org/10.1182/blood.V110.11.2515.2515
Published: 2007
Journal Articles

Preclinical studies of the pan-Bcl inhibitor obatoclax (GX015-070) in multiple myeloma

Suzanne Trudel, Zhi Hua Li, Jennifer Rauw, Rodger E. Tiedemann, Xiao Yan Wen, A. Keith Stewart
Journal: Blood
Blood (2007) 109 (12): 5430–5438.
https://doi.org/10.1182/blood-2006-10-047951
Published: 2007
Journal Articles

The inhibitory anti-FGFR3 antibody, PRO-001, is cytotoxic to t(4;14) multiple myeloma cells

Suzanne Trudel, A. Keith Stewart, Eran Rom, Ellen Wei, Zhi Hua Li, Sarit Kotzer, Irina Chumakov, Yossi Singer, Hong Chang, Sheng-Ben Liang, Avner Yayon
Journal: Blood
Blood (2006) 107 (10): 4039–4046.
https://doi.org/10.1182/blood-2005-10-4179
Published: 2006
Journal Articles

Studies of the Bcl Inhibitor GX15-070 in Multiple Myeloma Demonstrate Substantial Pre-Clinical Activity.

A. Keith Stewart, MD, Zhi Hua Li, Xiao Yan Wen, PhD, Jennifer Rauw, Latha Pathangey, P. Leif Bergsagel, MD, Suzanne Trudel, MD
Journal: Blood
Blood (2005) 106 (11): 1572.
https://doi.org/10.1182/blood.V106.11.1572.1572
Published: 2005
Journal Articles

Immunohistochemistry accurately predicts FGFR3 aberrant expression and t(4;14) in multiple myeloma

Brief Report
Hong Chang, A. Keith Stewart, Xiao Ying Qi, Zhi Hua Li, Qi Long Yi, Suzanne Trudel
Journal: Blood
Blood (2005) 106 (1): 353–355.
https://doi.org/10.1182/blood-2005-01-0033
Published: 2005
Journal Articles

CHIR-258, a novel, multitargeted tyrosine kinase inhibitor for the potential treatment of t(4;14) multiple myeloma

Suzanne Trudel, Zhi Hua Li, Ellen Wei, Marion Wiesmann, Hong Chang, Christine Chen, Donna Reece, Carla Heise, A. Keith Stewart
Journal: Blood
Blood (2005) 105 (7): 2941–2948.
https://doi.org/10.1182/blood-2004-10-3913
Published: 2005
Journal Articles

Targeting FGFR3 in t(4;14) Mutiple Myeloma: Pre-Clinical Studies of PRO-001, a Novel Anti-FGFR3 Neutralizing Antibody.

Suzanne Trudel, M.D., M.Sc., Ellen Wei, M.Sc., Zhi Hua Li, M.Sc., Eran Rom, Ph.D., Ira Chumakov, M.Sc., Yossi Singer, M.Sc., Chris Chen, M.D., Donna Reece, M.D., Joseph Mikhael, M.D., A. Keith Stewart, M.D., Avner Yayon, M.D., Ph.D.
Journal: Blood
Blood (2004) 104 (11): 2479.
https://doi.org/10.1182/blood.V104.11.2479.2479
Published: 2004
Journal Articles

Targeting Hematopoietic Cells Using a Blimp-1 Promoter Helper Dependent Adenoviruses.

Chang-Xin Shi, Ph.D, Xiao-Yan Wen, Ph.D, Ding-Yan Wang, Ph.D, Bo Gao, Ph.D, Gillian Sleep, Li-Hua Zhuang, Ph.D, Zhi-Hua Li, Mary M. Hitt, Ph.D, A. Keith Stewart, MD
Journal: Blood
Blood (2004) 104 (11): 5259.
https://doi.org/10.1182/blood.V104.11.5259.5259
Published: 2004
Journal Articles

CHIR258, a Novel Multi-Targeted Tyrosine Kinase Inhibitor, for the Treatment of t(4;14) Multiple Myeloma.

Suzanne Trudel, M.D., M.Sc., Zhi Hua Li, M.D., Ellen Wei, M.Sc., Marion Wiesmann, Ph.D., Katherine Rendahl, Ph.D., Eddie Moler, Ph.D., Chris Chen, M.D., Donna Reece, M.D., Joesph Mikhael, M.D., Carla Heise, Ph.D., A. Keith Stewart, M.D.
Journal: Blood
Blood (2004) 104 (11): 641.
https://doi.org/10.1182/blood.V104.11.641.641
Published: 2004
Journal Articles

A molecular compendium of genes expressed in multiple myeloma

Jaime O. Claudio, Esther Masih-Khan, Hongchang Tang, Jason Gonçalves, Michael Voralia, Zhi Hua Li, Vincent Nadeem, Eva Cukerman, Ofelia Francisco-Pabalan, Choong Chin Liew, James R. Woodgett, A. Keith Stewart
Journal: Blood
Blood (2002) 100 (6): 2175–2186.
https://doi.org/10.1182/blood-2002-01-0008
Published: 2002