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Journal Articles

Next-Generation STAT3 Inhibitors As Targeted Therapeutics in Chronic Myeloid Leukemia.

Ira L Kraft, BS, Anna M. Eiring, PhD, Brent DG Page, BS, Clinton C Mason, PhD, Zhimin Gu, PhD, Jamshid S Khorashad, MD, PhD, David J Anderson, BA, Anthony D Pomicter, MS, Kimberly R Reynolds, MS, Johanna Estrada, Matthew S Zabriskie, BS, Patrick T Gunning, PhD, Thomas O'Hare, PhD, Michael W Deininger, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 2445.
https://doi.org/10.1182/blood.V120.21.2445.2445
Published: 2012
Journal Articles

STAT3 Inhibition Synergizes with BCR-ABL1 Inhibition to Overcome Kinase-Independent TKI Resistance in Chronic Myeloid Leukemia (CML)

Anna M. Eiring, PhD, Ira L Kraft, BS, Brent DG Page, BS, David J Anderson, BA, Zhimin Gu, PhD, Jamshid S Khorashad, MD, PhD, Anthony D Pomicter, MS, Kimberly R Reynolds, MS, Matthew S Zabriskie, BS, Richard Moriggl, PhD, Patrick T Gunning, PhD, Thomas O'Hare, PhD, Michael W Deininger, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 31.
https://doi.org/10.1182/blood.V120.21.31.31
Published: 2012
Journal Articles

BP-2-047, a Novel Small-Molecule Inhibitor of Stat3 Is Active in Myeloma Pre-Clinical Models: Rationale for Treatment of Stat3-Dependent Multiple Myeloma

Victor Hugo Jimenez-Zepeda, MD, Brent DG Page, BS, Li Zhia Hua, Ellen Wei, Leif Bergsagel, M.D., Patrick T Gunning, PhD, Suzanne Trudel, MD, MSC, FRCPC
Journal: Blood
Blood (2012) 120 (21): 576.
https://doi.org/10.1182/blood.V120.21.576.576
Published: 2012
Journal Articles

The Potent STAT3/5 Inhibitor, BP-1-102 Demonstrates Significant Anti-Tumor Activity Against Waldenström Macroglobulinemia

Danielle C Croucher, Victor H Jimenez-Zepeda, MD, PD, Zhi Hua Li, Ellen Wei, Brent DG Page, James Turkson, Patrick T Gunning, Suzanne Trudel, MD, MSC, FRCPC
Journal: Blood
Blood (2011) 118 (21): 5101.
https://doi.org/10.1182/blood.V118.21.5101.5101
Published: 2011
Journal Articles

Studies of BP-1-102, a Novel Direct Small-Molecule Inhibitor of Stat3 Demonstrates Substantial Anti-Myeloma Pre-Clinical Activity

Victor H Jimenez-Zepeda, MD, PD, Zhi Hua Li, Brent DG Page, Seda Zeng, Ellen Wei, Chungyee Leung-Hagesteijn, James Turkson, Patrick T. Gunning, Suzanne Trudel, MD, MSC, FRCPC
Journal: Blood
Blood (2010) 116 (21): 138.
https://doi.org/10.1182/blood.V116.21.138.138
Published: 2010