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Journal Articles

BP-2-047, a Novel Small-Molecule Inhibitor of Stat3 Is Active in Myeloma Pre-Clinical Models: Rationale for Treatment of Stat3-Dependent Multiple Myeloma

Victor Hugo Jimenez-Zepeda, MD, Brent DG Page, BS, Li Zhia Hua, Ellen Wei, Leif Bergsagel, M.D., Patrick T Gunning, PhD, Suzanne Trudel, MD, MSC, FRCPC
Journal: Blood
Blood (2012) 120 (21): 576.
https://doi.org/10.1182/blood.V120.21.576.576
Published: 2012
Journal Articles

The Potent STAT3/5 Inhibitor, BP-1-102 Demonstrates Significant Anti-Tumor Activity Against Waldenström Macroglobulinemia

Danielle C Croucher, Victor H Jimenez-Zepeda, MD, PD, Zhi Hua Li, Ellen Wei, Brent DG Page, James Turkson, Patrick T Gunning, Suzanne Trudel, MD, MSC, FRCPC
Journal: Blood
Blood (2011) 118 (21): 5101.
https://doi.org/10.1182/blood.V118.21.5101.5101
Published: 2011
Journal Articles

Studies of BP-1-102, a Novel Direct Small-Molecule Inhibitor of Stat3 Demonstrates Substantial Anti-Myeloma Pre-Clinical Activity

Victor H Jimenez-Zepeda, MD, PD, Zhi Hua Li, Brent DG Page, Seda Zeng, Ellen Wei, Chungyee Leung-Hagesteijn, James Turkson, Patrick T. Gunning, Suzanne Trudel, MD, MSC, FRCPC
Journal: Blood
Blood (2010) 116 (21): 138.
https://doi.org/10.1182/blood.V116.21.138.138
Published: 2010
Journal Articles

A Phase II Study of Lenalidomide in Previously Untreated, Symptomatic Chronic Lymphocytic Leukemia (CLL)

Christine Chen, MD, Harminder Paul, Wei Xu, PhD, Vishal Kukreti, Suzanne Trudel, Ellen Wei, Zhi Hua Li, Joseph Brandwein, Mariela Pantoja, Chungyee Leung-Hagensteijn
Journal: Blood
Blood (2008) 112 (11): 44.
https://doi.org/10.1182/blood.V112.11.44.44
Published: 2008
Journal Articles

A Phase II Study of Lenalidomide in Previously Untreated, Symptomatic Chronic Lymphocytic Leukemia (CLL).

Christine I. Chen, MD, Harminder Paul, Pantoja Mariela, Joseph Brandwein, MD, Vishal Kukreti, MD, Suzanne Trudel, MD, Ellen Wei, Jieffei Tong, Mike Moran
Journal: Blood
Blood (2007) 110 (11): 2042.
https://doi.org/10.1182/blood.V110.11.2042.2042
Published: 2007
Journal Articles

MIP-1α (CCL3) is a downstream target of FGFR3 and RAS-MAPK signaling in multiple myeloma

Esther Masih-Khan, Suzanne Trudel, Carla Heise, Zhihua Li, Joshua Paterson, Vincent Nadeem, Ellen Wei, David Roodman, Jaime O. Claudio, P. Leif Bergsagel, A. Keith Stewart
Journal: Blood
Blood (2006) 108 (10): 3465–3471.
https://doi.org/10.1182/blood-2006-04-017087
Published: 2006
Includes: Supplemental data
Journal Articles

The inhibitory anti-FGFR3 antibody, PRO-001, is cytotoxic to t(4;14) multiple myeloma cells

Suzanne Trudel, A. Keith Stewart, Eran Rom, Ellen Wei, Zhi Hua Li, Sarit Kotzer, Irina Chumakov, Yossi Singer, Hong Chang, Sheng-Ben Liang, Avner Yayon
Journal: Blood
Blood (2006) 107 (10): 4039–4046.
https://doi.org/10.1182/blood-2005-10-4179
Published: 2006
Journal Articles

Macrophage Inflammatory Protein (MIP)-1alpha (CCL3) Is a Downstream Target of FGFR3 and RAS Signaling in Multiple Myeloma.

Esther Masih-Khan, Suzanne Trudel, MD, ZhiHua Li, Vincent Nadeem, Ellen Wei, Joshua Paterson, Jaime O. Claudio, A. Keith Stewart, MD
Journal: Blood
Blood (2005) 106 (11): 251.
https://doi.org/10.1182/blood.V106.11.251.251
Published: 2005
Journal Articles

CHIR-258, a novel, multitargeted tyrosine kinase inhibitor for the potential treatment of t(4;14) multiple myeloma

Suzanne Trudel, Zhi Hua Li, Ellen Wei, Marion Wiesmann, Hong Chang, Christine Chen, Donna Reece, Carla Heise, A. Keith Stewart
Journal: Blood
Blood (2005) 105 (7): 2941–2948.
https://doi.org/10.1182/blood-2004-10-3913
Published: 2005
Journal Articles

Targeting FGFR3 in t(4;14) Mutiple Myeloma: Pre-Clinical Studies of PRO-001, a Novel Anti-FGFR3 Neutralizing Antibody.

Suzanne Trudel, M.D., M.Sc., Ellen Wei, M.Sc., Zhi Hua Li, M.Sc., Eran Rom, Ph.D., Ira Chumakov, M.Sc., Yossi Singer, M.Sc., Chris Chen, M.D., Donna Reece, M.D., Joseph Mikhael, M.D., A. Keith Stewart, M.D., Avner Yayon, M.D., Ph.D.
Journal: Blood
Blood (2004) 104 (11): 2479.
https://doi.org/10.1182/blood.V104.11.2479.2479
Published: 2004
Journal Articles

CHIR258, a Novel Multi-Targeted Tyrosine Kinase Inhibitor, for the Treatment of t(4;14) Multiple Myeloma.

Suzanne Trudel, M.D., M.Sc., Zhi Hua Li, M.D., Ellen Wei, M.Sc., Marion Wiesmann, Ph.D., Katherine Rendahl, Ph.D., Eddie Moler, Ph.D., Chris Chen, M.D., Donna Reece, M.D., Joesph Mikhael, M.D., Carla Heise, Ph.D., A. Keith Stewart, M.D.
Journal: Blood
Blood (2004) 104 (11): 641.
https://doi.org/10.1182/blood.V104.11.641.641
Published: 2004