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Journal Articles

Multi-endpoint AI morphology model (MEAM) enhances risk prediction for vascular events and disease progression in MPNs

Free
Xuezi Hu, Alan Aberdeen, Sharon Ruane, Rosalin Cooper, Timothy Ebsworth, Sanam Loghavi, David Ross, Diana Iarossi, Markus Tiemann, Amin Turki, Andrew Sung, Mingyi Chen, Zijun Xu-Monette, Ken H. Young, Anna Godfrey, Jyoti Nangalia, Joanna Baxter, Anthony Green, Mary Frances McMullin, Adam Mead, Claire Harrison, Jens Rittscher, Korsuk Sirinukunwattana, Daniel Royston
Journal: Blood
Blood (2025) 146 (Supplement 1): 5599.
https://doi.org/10.1182/blood-2025-5599
Published: 2025
Journal Articles

Toward precision pathology: Deep learning supported fibrosis grading augments performance of international hematopathologists in a large real-world cohort

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Timothy Ebsworth, Sharon Ruane, Neha Bhardwaj, Rosalin Cooper, Anna Green, Deborah Hay, Jana Ihlow, Fatima Jelloul, Rashmi Kanagal-Shamanna, Philip Macklin, Vidhya Manohar, Edoardo Olmeda, Mark Ong, Carlo Pescia, Andres Quesada, Saad Bashir, Sam Maxwell, Korsuk Sirinukunwattana, Alan Aberdeen, Jens Rittscher, Daniel Royston
Journal: Blood
Blood (2025) 146 (Supplement 1): 4335.
https://doi.org/10.1182/blood-2025-4335
Published: 2025
Journal Articles

Mapping the Human Bone Marrow in Myeloproliferative Neoplasia Using Spatial Transcriptomics

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Rosalin Cooper, Emily Thomas, Dawood Muhammad, Carlo Pescia, Anna Sozanska, Oliver McCallion, Hosuk Ryou, Renuka Teague, Alan King Lun Liu, Joanna Hester, Fadi Issa, Bethan Psaila, Adam J Mead, Jens Rittscher, Dan Woodcock, Daniel Royston
Journal: Blood
Blood (2024) 144 (Supplement 1): 876.
https://doi.org/10.1182/blood-2024-205266
Published: 2024
Journal Articles

Spatial Transcriptomics Identifies Aberrant Communication between Dendritic Cells and Leukemia Stem Cells As a Therapeutically Targetable Axis in Juvenile Myelomonocytic Leukemia

Free
Eleni Louka, Kristian Gurashi, Sean Wen, Mariolina Salio, Christina Simoglou Karali, Roman Doll, Sally-Ann Clark, Anastasia Kosmidou, Rosalin Cooper, Daniel Royston, Deena Iskander, Nawshad Hayder, Renuka Teague, Cristina Tormo Garcia, Maria Greco, Paola Vargas Gutierrez, Joshua Bull, Anupama Rao, Irene Roberts, Adam J Mead
Journal: Blood
Blood (2024) 144 (Supplement 1): 822.
https://doi.org/10.1182/blood-2024-208902
Published: 2024