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Journal Articles

MALT1 Degradation with a Proteolysis-Targeting Chimera for the Treatment of Activated B-Cell Type Diffuse Large B-Cell Lymphoma

Madhav R Seshadri, Lorena Fontan, Prasanna Sreevatsan, David Scott, John Hatcher, Guangyan Du, Min Xia, Ilkay Us, Nathanael Gray, Ari Melnick
Journal: Blood
Blood (2021) 138 (Supplement 1): 269.
https://doi.org/10.1182/blood-2021-153855
Published: 2021
Journal Articles

Identification of MALT1 feedback mechanisms enables rational design of potent antilymphoma regimens for ABC-DLBCL

Lorena Fontan, Rebecca Goldstein, Gabriella Casalena, Matthew Durant, Matthew R. Teater, Jimmy Wilson, Jude Phillip, Min Xia, Shivem Shah, Ilkay Us, Himaly Shinglot, Ankur Singh, Giorgio Inghirami, Ari Melnick
Journal: Blood
Blood (2021) 137 (6): 788–800.
https://doi.org/10.1182/blood.2019004713
Published: 2021
Includes: Supplemental data
Journal Articles

Mapping MALT1 Signaling Connectivity Unveils Novel B-Cell Feedback Mechanisms Directing Assembly of Potent Anti-Lymphoma Regimens

Lorena Fontan, PhD, Matthew Durant, Rebecca Goldstein, PhD, Matthew R Teater, PhD, Gabriella Casalena, PhD, Min Xia, PhD, Jimmy Wilson, Ilkay Us, Giorgio Inghirami, MD, Ari Melnick, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 173.
https://doi.org/10.1182/blood-2019-130516
Published: 2019
Journal Articles

Chemically Induced Degradation of MALT1 to Treat B-Cell Lymphomas

Lorena Fontan, PhD, John Hatcher, PhD, David Scott, Qi Qiao, Ilkay Us, Guangyan Du, Matthew Durant, Jimmy Wilson, Hao Wu, PhD, Nathanael Gray, Ari Melnick, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2073.
https://doi.org/10.1182/blood-2019-130666
Published: 2019
Journal Articles

RNA Interference Screen Implicates TNFAIP3 and FOXO1 in MALT1 Inhibition Resistance

Lorena Fontan, PhD, Rebecca Goldstein, PhD, Gabriella Casalena, PhD, Himaly Shinglot, MS, Ilkay Us, MS, Haiying Ju, MS, Yanwen Jiang, PhD, Natalia Bilchuk, MS, Ari Melnick, MD
Journal: Blood
Blood (2016) 128 (22): 837.
https://doi.org/10.1182/blood.V128.22.837.837
Published: 2016