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David J. Chung
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Journal Articles

Antigen escape as a shared mechanism of resistance to BCMA-directed therapies in multiple myeloma

Brief Report
Ross S. Firestone, Nicholas D. Socci, Tala Shekarkhand, Menglei Zhu, Wei Ge Qin, Malin Hultcrantz, Sham Mailankody, Carlyn Rose Tan, Neha Korde, Alexander M. Lesokhin, Hani Hassoun, Urvi Shah, Kylee H. Maclachlan, Sridevi Rajeeve, Heather J. Landau, Michael Scordo, Gunjan L. Shah, Oscar B. Lahoud, Sergio Giralt, Kazunori Murata, Saad Z. Usmani, David J. Chung
Journal: Blood
Blood (2024) 144 (4): 402–407.
https://doi.org/10.1182/blood.2023023557
Published: 2024
Includes: Supplemental data
Journal Articles

Tracking the evolution of therapy-related myeloid neoplasms using chemotherapy signatures

Benjamin Diamond, Bachisio Ziccheddu, Kylee Maclachlan, Justin Taylor, Eileen Boyle, Juan Arango Ossa, Jacob Jahn, Maurizio Affer, Tulasigeri M. Totiger, David Coffey, Namrata Chandhok, Justin Watts, Luisa Cimmino, Sydney X. Lu, Niccolò Bolli, Kelly Bolton, Heather Landau, Jae H. Park, Karuna Ganesh, Andrew McPherson, Mikkael A. Sekeres, Alexander Lesokhin, David J. Chung, Yanming Zhang, Caleb Ho, Mikhail Roshal, Jeffrey Tyner, Stephen Nimer, Elli Papaemmanuil, Saad Usmani, Gareth Morgan, Ola Landgren, Francesco Maura
Journal: Blood
Blood (2023) 141 (19): 2359–2371.
https://doi.org/10.1182/blood.2022018244
Published: 2023
Includes: Supplemental data
Journal Articles

Fc-Mediated Antibody Effector Function, Inflammation Resolution and Oligoclonality on TCR Rearrangements Predict Sustained MRD Negativity in Newly Diagnosed Multiple Myeloma Treated with Immunotherapy Regimens

Eileen M Boyle, Francesco Maura, David Coffey, Kylee H Maclachlan, Benjamin Diamond, Hussein Ghamlouch, Dylan Gagler, Patrick Blaney, Bachisio Ziccheddu, Yubao Wang, Emily Guzman, Avital Tenenbaum, Ariel Siegel, Xiaoyi Chen, Gaurav Varma, James E Hoffman, Dickran Kazandjian, Hani Hassoun, Sham Mailankody, Urvi A Shah, Carlyn Tan, Malin Hultcrantz, Michael Scordo, Gunjan L. Shah, Heather Landau, David J. Chung, Sergio A Giralt, Yanming Zhang, Ahmet Dogan, Alexander M Lesokhin, Dennis Verducci, Faith E Davies, Saad Usmani, Neha Korde, Ola Landgren, Gareth J. Morgan
Journal: Blood
Blood (2022) 140 (Supplement 1): 249–251.
https://doi.org/10.1182/blood-2022-165500
Published: 2022
Journal Articles

A Phase 2 Trial of Colesevelam for Lenalidomide-Associated Diarrhea

Malin Hultcrantz, Hani Hassoun, Neha Korde, Sham Mailankody, Tala Shekarkhand, Miranda Burge, Kylee H Maclachlan, Dhwani Patel, Urvi A Shah, David J. Chung, Michael Scordo, Kelly Barnett, Jenna Blaslov, Meghan Salcedo, Julia Caple, Linh Tran, Selena Hamid, Oscar B Lahoud, Heather Landau, Gunjan L. Shah, Sergio A Giralt, Andriy Derkach, Carlyn Tan, Cody Peer, William D. Figg, Sr., Saad Usmani, Ola Landgren, Alexander M Lesokhin
Journal: Blood
Blood (2022) 140 (Supplement 1): 4454–4456.
https://doi.org/10.1182/blood-2022-164851
Published: 2022
Journal Articles

Stem Cell Autograft Minimal Residual Disease Negativity Improves Outcomes after Autotransplant for Multiple Myeloma

Noriko Nishimura, Samantha Brown, Sean M. Devlin, Parastoo B. Dahi, Heather Landau, Oscar B Lahoud, Michael Scordo, Gunjan L. Shah, Hani Hassoun, Malin Hultcrantz, Neha Korde, Alexander M Lesokhin, Sham Mailankody, Urvi A Shah, Carlyn Tan, Saad Usmani, Sergio A. Giralt, David J. Chung, Gaurav Gupta, Elena Maryamchik, Evangelos Ntrivalas, Mikhail Roshal
Journal: Blood
Blood (2022) 140 (Supplement 1): 620–622.
https://doi.org/10.1182/blood-2022-160271
Published: 2022
Journal Articles

A Randomized Placebo Controlled Study of a Plant-Based Dietary Versus Supplement Versus Placebo Intervention in Patients with Monoclonal Gammopathy of Undetermined Significance (MGUS) and Smoldering Multiple Myeloma (SMM) - the Nutrition Prevention (NUTRIVENTION-3) Study

Urvi A. Shah, Francesca Castro, Aishwarya Anuraj, Eliana Schach, Andriy Derkach, Nisha S. Joseph, Peter A. Adintori, Laura Guttentag, Jenna Blaslov, Justin R. Cross, Kylee H. Maclachlan, Sham Mailankody, Neha Korde, Carlyn Tan, Malin Hultcrantz, Hani Hassoun, Oscar B. Lahoud, Gunjan L. Shah, Michael Scordo, Jonathan U. Peled, David J. Chung, Heather Landau, Jun J. Mao, Neil M. Iyengar, Saad Usmani, Sergio A. Giralt, Marcel R.M. van den Brink, Alexander M. Lesokhin
Journal: Blood
Blood (2022) 140 (Supplement 1): 5052–5055.
https://doi.org/10.1182/blood-2022-159794
Published: 2022
Journal Articles

Tracking the Evolution of Therapy-Related Myeloid Neoplasms Using Chemotherapy Signatures

Bachisio Ziccheddu, Benjamin Diamond, Kylee H Maclachlan, Justin Taylor, Eileen M Boyle, Juan E. Arango Ossa, Jahn Jacob, Maurizio Affer, Tulasigeri M Totiger, David Coffey, Justin Watts, Sydney X. Lu, Niccolo Bolli, Kelly L Bolton, Jae H Park, Heather Landau, Karuna Ganesh, Andrew McPherson, Mikkael A. Sekeres, Alexander M Lesokhin, David J. Chung, Yanming Zhang, Caleb Ho, Mikhail Roshal, Jeffrey W. Tyner, Stephen D Nimer, Elli Papaemmanuil, Saad Usmani, Gareth J. Morgan, Ola Landgren, Francesco Maura
Journal: Blood
Blood (2022) 140 (Supplement 1): 2088–2090.
https://doi.org/10.1182/blood-2022-158992
Published: 2022
Journal Articles

Stem Cell Mobilization Characteristics for Transplant Eligible Patients with Newly Diagnosed Multiple Myeloma (NDMM) Treated with Carfilzomib, Lenalidomide, Dexamethasone, and Daratumumab (KRd-Dara)

Manisha Bhutani, Myra Robinson, Shebli Atrash, Nicole Watts, Barry Paul, Saurabh Chhabra, Neha Korde, Xhevahire Begic, David M Foureau, David J. Chung, Mauricio Pineda-Roman, Brinda Koya, Cindy Varga, Jing Ai, Natonya Daniels, Sarah Norek, Sara A Sutton, Michelle B Anderson, Ashley N Jewell, Paul W Eldridge, Donna Acampora, James T Symanowski, Luciano J. Costa, Saad Usmani, Peter M. Voorhees
Journal: Blood
Blood (2022) 140 (Supplement 1): 4393–4395.
https://doi.org/10.1182/blood-2022-160071
Published: 2022
Journal Articles

Carfilzomib, Lenalidomide and Dexamethasone (KRd) Vs Bortezomib, Lenalidomide, and Dexamethasone (VRd) As Induction Therapy in Newly Diagnosed High-Risk Multiple Myeloma

Carlyn Tan, David Nemirovsky, Andriy Derkach, Malin Hultcrantz, Hani Hassoun, Sham Mailankody, Urvi A Shah, Dhwani Patel, Kylee H Maclachlan, Oscar B Lahoud, Gunjan L. Shah, Michael Scordo, David J. Chung, Heather Landau, Sergio A Giralt, Alexander M Lesokhin, Neha Korde, Saad Usmani
Journal: Blood
Blood (2022) 140 (Supplement 1): 1817–1819.
https://doi.org/10.1182/blood-2022-169161
Published: 2022
Journal Articles

A Pilot Plant Based Dietary Intervention in MGUS and SMM Patients with Elevated BMI Is Feasible and Associated with Improvements in Metabolic and Microbiome Biomarkers of Progression

Urvi A. Shah, Andriy Derkach, Francesca Castro, Aishwarya Anuraj, Jenna Blaslov, Linh Tran, Peter A. Adintori, Miranda Burge, Sharon Funkhouser, Kinga Hosszu, Justin R. Cross, Michael N. Pollak, Devin P. McAvoy, David Nemirovsky, Kylee H. Maclachlan, Sham Mailankody, Neha Korde, Carlyn Tan, Malin Hultcrantz, Dhwani Patel, Hani Hassoun, Gunjan L. Shah, Michael Scordo, Oscar B. Lahoud, David J. Chung, Marius E. Mayerhoefer, Jonathan U. Peled, Heather Landau, Anita D'Souza, Ola Landgren, Sergio A. Giralt, Neil M. Iyengar, Saad Usmani, Marcel R.M. van den Brink, Alexander M. Lesokhin
Journal: Blood
Blood (2022) 140 (Supplement 1): 5066–5069.
https://doi.org/10.1182/blood-2022-163281
Published: 2022
Journal Articles

Genomic Determinants of Resistance in Newly Diagnosed Multiple Myeloma Treated with Targeted-Immunotherapy

Francesco Maura, Eileen Boyle, David Coffey, Kylee H Maclachlan, Benjamin Diamond, Patrick Blaney, Dylan Gagler, Bachisio Ziccheddu, Hussein Ghamlouch, Yubao Wang, James E. Hoffman, Dickran Kazandjian, Hani Hassoun, Emily Guzman, Sham Mailankody, Urvi A Shah, Carlyn Tan, Malin Hultcrantz, Michael Scordo, Gunjan L. Shah, Heather Landau, David J. Chung, Sergio A. Giralt, Yanming Zhang, Ahmet Dogan, Alexander M Lesokhin, Dennis Verducci, Faith E. Davies, Saad Usmani, Neha Korde, Gareth J. Morgan, Ola Landgren
Journal: Blood
Blood (2022) 140 (Supplement 1): 1137–1139.
https://doi.org/10.1182/blood-2022-160308
Published: 2022
Journal Articles

Belantamab Mafodotin in Patients with Relapsed/Refractory Multiple Myeloma, a Real-World Single Center Experience

Malin Hultcrantz, Andriy Derkach, Hani Hassoun, Neha Korde, Kylee H Maclachlan, Sham Mailankody, Dhwani Patel, Urvi A Shah, Carlyn Tan, Theresia Akhlaghi, Issam S. Hamadeh, David J. Chung, Oscar B Lahoud, Heather Landau, Michael Scordo, Gunjan L. Shah, Sergio A. Giralt, Alexander M Lesokhin, Saad Usmani
Journal: Blood
Blood (2022) 140 (Supplement 1): 7246–7248.
https://doi.org/10.1182/blood-2022-171077
Published: 2022
Journal Articles

Genomic and Immune Signatures Predict Sustained MRD Negativity in Newly Diagnosed Multiple Myeloma Patients Treated with Daratumumab, Carfilzomib, Lenalidomide, and Dexamethasone (D-KRd)

Francesco Maura, Eileen M Boyle, Benjamin Diamond, Patrick Blaney, Hussein Ghamlouch, Bachisio Ziccheddu, Yubao Wang, Kylee H Maclachlan, James E. Hoffman, Hani Hassoun, Sham Mailankody, Urvi A Shah, Carlyn Tan, Malin Hultcrantz, Michael Scordo, Dickran Kazandjian, Gunjan L Shah, Heather J Landau, David J. Chung, Sergio Giralt, Benedetto Bruno, Yanming Zhang, Arnaldo A Arbini, Ahmet Dogan, Alexander Lesokhin, Faith E Davies, Neha Korde, Gareth J Morgan, Ola Landgren
Journal: Blood
Blood (2021) 138 (Supplement 1): 325.
https://doi.org/10.1182/blood-2021-149112
Published: 2021
Journal Articles

Impact of Autologous Hematopoietic Cell Transplant (HCT) Followed By Dendritic Cell/Myeloma Fusion Vaccine with Lenalidomide Maintenance in Increasing Multiple Myeloma (MM) Immunity (BMT CTN 1401)

David J. Chung, Nina Shah, Dina Stroopinsky, Juan WU, Lina Bisharat, Natalie S. Callander, Brent R. Logan, Kenneth C. Anderson, Thinle Chodon, Meera Mohan, Steven Devine, Yvonne A. Efebera, Nancy Geller, Peiman Hematti, Leona A. Holmberg, Alan Howard, Bryon Johnson, Hillard M Lazarus, Ehsan Malek, Philip L. McCarthy, David H. McKenna, Adam M. Mendizabal, Nikhil C. Munshi, Lynn O'Donnell, Aaron P. Rapoport, Ajay K. Nooka, Jane Reese, Robert J. Soiffer, Lynne Uhl, Giulia Cheloni, Dimitra Karagkouni, Ioannis Vlachos, James W. Young, Jacalyn Rosenblatt, Edmund K. Waller, Marcelo C Pasquini, David Avigan
Journal: Blood
Blood (2021) 138 (Supplement 1): 899.
https://doi.org/10.1182/blood-2021-149659
Published: 2021
Journal Articles

Chemotherapy-Related Mutational Signatures Reveal the Origins of Therapy-Related Myeloid Neoplasms

Benjamin Diamond, Bachisio Ziccheddu, Eileen M Boyle, Kylee H Maclachlan, Juan Arango Ossa, Justin Taylor, Justin Watts, Sydney X. Lu, Venkata D Yellapantula, Christopher Famulare, Monika Chojnacka, Arjun Raj Rajanna, Emilia Mason, David G. Coffey, James E. Hoffman, Dickran Kazandjian, Terrence J Bradley, Menglei Zhu, Niccolo Bolli, Elli Papaemmanuil, Kelly L. Bolton, Michael Scordo, Oscar B Lahoud, Eytan M. Stein, Craig S. Sauter, Hani Hassoun, Sham Mailankody, Neha Korde, Malin Hultcrantz, Urvi A Shah, Gunjan L Shah, Jae H Park, Heather J Landau, Karuna Ganesh, Mikkael A. Sekeres, Stephen Nimer, David J. Chung, Caleb Ho, Mikhail Roshal, Alexander Lesokhin, Gareth J. Morgan, Ola Landgren, Francesco Maura
Journal: Blood
Blood (2021) 138 (Supplement 1): 3271.
https://doi.org/10.1182/blood-2021-145927
Published: 2021
Journal Articles

Timing and Immune Status after Cellular Therapies Predict Response to COVID-19 Vaccines

Roni Tamari, Ioannis Politikos, David Knorr, Santosha Vardhana, Jennifer Young, Leeann Marcello, Sital Doddi, Sean M Devlin, Lakshmi Ramanathan, Melissa S. Pessin, Erica Dunn, Meighan A. Palazzo, Christina Bravo, Genovefa A. Papanicolaou, Mini Kamboj, Miguel-Angel Perales, David J. Chung, Gunjan L Shah
Journal: Blood
Blood (2021) 138 (Supplement 1): 3891.
https://doi.org/10.1182/blood-2021-151376
Published: 2021
Journal Articles

Belantamab Mafodotin in Patients with Relapsed/Refractory Multiple Myeloma, a Real-World Experience

Malin Hultcrantz, Jennifer Orozco, Tim J Peterson, Andriy Derkach, Hani Hassoun, Neha Korde, Sydney X. Lu, Sham Mailankody, Dhwani Patel, Urvi A Shah, Carlyn Tan, Kylee H Maclachlan, David J. Chung, Heather J Landau, Gunjan L Shah, Oscar B Lahoud, Michael Scordo, Ola Landgren, Sergio Giralt, Alexander Lesokhin
Journal: Blood
Blood (2021) 138 (Supplement 1): 1644.
https://doi.org/10.1182/blood-2021-153443
Published: 2021
Journal Articles

Phase I First-in-Class Trial of MCARH109, a G Protein Coupled Receptor Class C Group 5 Member D (GPRC5D) Targeted CAR T Cell Therapy in Patients with Relapsed or Refractory Multiple Myeloma

Sham Mailankody, Claudia Diamonte, Lisa Fitzgerald, Peter Kane, Xiuyan Wang, Devanjan S. Sikder, Brigitte Senechal, Vladimir P. Bermudez, Diana Frias, Justina Morgan, Patrick Grant, Terence J Purdon, Kinga Hosszu, Sean M Devlin, Urvi A Shah, Jonathan Landa, Alexander Lesokhin, Neha Korde, Hani Hassoun, Carlyn Tan, Malin Hultcrantz, Gunjan L. Shah, Heather J Landau, David J. Chung, Michael Scordo, Mikhail Roshal, Ola Landgren, Ahmet Dogan, Sergio A Giralt, Jae H Park, Isabelle Rivière, Renier J Brentjens, Eric L Smith
Journal: Blood
Blood (2021) 138 (Supplement 1): 827.
https://doi.org/10.1182/blood-2021-153204
Published: 2021
Journal Articles

Daratumumab Versus Lenalidomide Maintenance Therapy for Multiple Myeloma: A Randomized Pilot Study Comparing Patient-Reported Health Related Quality of Life Measures

Urvi A Shah, Maria Malik, Kelly Werner, Miranda Burge, Sean M Devlin, Sham Mailankody, Neha Korde, Malin Hultcrantz, Hani Hassoun, Carlyn Tan, Kylee H Maclachlan, Sydney X. Lu, Dhwani Patel, Audrey Hamilton, Michael Scordo, Parastoo B. Dahi, Oscar B Lahoud, David J. Chung, Heather J Landau, Gunjan L. Shah, Sergio A Giralt, Alexander Lesokhin, Ola Landgren
Journal: Blood
Blood (2021) 138 (Supplement 1): 4762.
https://doi.org/10.1182/blood-2021-150684
Published: 2021
Journal Articles

Fecal microbiota diversity disruption and clinical outcomes after auto-HCT: a multicenter observational study

Niloufer Khan, Sarah Lindner, Antonio L. C. Gomes, Sean M. Devlin, Gunjan L. Shah, Anthony D. Sung, Craig S. Sauter, Heather J. Landau, Parastoo B. Dahi, Miguel-Angel Perales, David J. Chung, Alexander M. Lesokhin, Anqi Dai, Annelie Clurman, John B. Slingerland, Ann E. Slingerland, Daniel G. Brereton, Paul A. Giardina, Molly Maloy, Gabriel K. Armijo, Carlos Rondon-Clavo, Emily Fontana, Lauren Bohannon, Sendhilnathan Ramalingam, Amy T. Bush, Meagan V. Lew, Julia A. Messina, Eric Littmann, Ying Taur, Robert R. Jenq, Nelson J. Chao, Sergio Giralt, Kate A. Markey, Eric G. Pamer, Marcel R. M. van den Brink, Jonathan U. Peled
Journal: Blood
Blood (2021) 137 (11): 1527–1537.
https://doi.org/10.1182/blood.2020006923
Published: 2021
Includes: Supplemental data