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Mikhail Roshal
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Journal Articles

Polytypic B-Cells, B-Cell Lymphoproliferative Disorders/Lymphomas, and Neoplastic T-Cells Divergently Differentiate from TET2 -/ DNMT3A -Mutated Clonal Hematopoiesis in Patients with Follicular Helper T-Cell Lymphomas/Lymphoproliferative Disorders

Natasha Lewis, Kseniya Petrova-Drus, Rohan Sardana, Qi Gao, Shenon Sethi, Wenbin Xiao, Mikhail Roshal, Jeeyeon Baik, Himanshu Bhurtel, Alison Moskowitz, Steven M. Horwitz, Ahmet Dogan
Journal: Blood
Blood (2023) 142 (Supplement 1): 849.
https://doi.org/10.1182/blood-2023-187320
Published: 2023
Journal Articles

Deconvoluting Clonal and Cellular Architecture in IDH -Mutant Acute Myeloid Leukemia

Maria Sirenko, Soobeom Lee, Zhengxi Sun, Ronan Chaligne, Georgios Asimomitis, Charlotte K Brierley, Elsa Bernard, Sheng F. Cai, Robert M Myers, Bettina Nadorp, Max F Levine, Dylan Domenico, Juan E Arango Ossa, Juan Santiago Medina Martinez, Kamal Menghrajani, Audrey Lasry, Alice Mims, Helee Desai, Andrea Laganson, Christopher Famulare, Minal Patel, Gerard Lozanski, Sanam Loghavi, Kelly L. Bolton, Aaron D. Viny, Mikhail Roshal, Ross L Levine, Eytan M. Stein, Dan A. Landau, Ann-Kathrin Eisfeld, Iannis Aifantis, Elli Papaemmanuil
Journal: Blood
Blood (2023) 142 (Supplement 1): 1591.
https://doi.org/10.1182/blood-2023-186322
Published: 2023
Journal Articles

Classic Hodgkin Lymphomas Display Neuronal-Glial Lineage Transdifferentiation

Mirca S. Saurty-Seerunghen, Sara Moein, Tsega-Ab Abera, Xiaotian Sun, Sohani Sharma, Chhiring Lama, Mansi Totwani, Shira Rosenberg, Qi Gao, Neelang Parghi, Amy Chadburn, Kui Nie, Vicenta Trujillo Alonso, Elizabeth Bier, Jenny Xiang, Ethel Cesarman, Wayne Tam, Mikhail Roshal, Lisa Giulino Roth, Anna S Nam
Journal: Blood
Blood (2023) 142 (Supplement 1): 715.
https://doi.org/10.1182/blood-2023-189533
Published: 2023
Journal Articles

Tracking the evolution of therapy-related myeloid neoplasms using chemotherapy signatures

Benjamin Diamond, Bachisio Ziccheddu, Kylee Maclachlan, Justin Taylor, Eileen Boyle, Juan Arango Ossa, Jacob Jahn, Maurizio Affer, Tulasigeri M. Totiger, David Coffey, Namrata Chandhok, Justin Watts, Luisa Cimmino, Sydney X. Lu, Niccolò Bolli, Kelly Bolton, Heather Landau, Jae H. Park, Karuna Ganesh, Andrew McPherson, Mikkael A. Sekeres, Alexander Lesokhin, David J. Chung, Yanming Zhang, Caleb Ho, Mikhail Roshal, Jeffrey Tyner, Stephen Nimer, Elli Papaemmanuil, Saad Usmani, Gareth Morgan, Ola Landgren, Francesco Maura
Journal: Blood
Blood (2023) 141 (19): 2359–2371.
https://doi.org/10.1182/blood.2022018244
Published: 2023
Includes: Supplemental data
Journal Articles

Tracking the Evolution of Therapy-Related Myeloid Neoplasms Using Chemotherapy Signatures

Bachisio Ziccheddu, Benjamin Diamond, Kylee H Maclachlan, Justin Taylor, Eileen M Boyle, Juan E. Arango Ossa, Jahn Jacob, Maurizio Affer, Tulasigeri M Totiger, David Coffey, Justin Watts, Sydney X. Lu, Niccolo Bolli, Kelly L Bolton, Jae H Park, Heather Landau, Karuna Ganesh, Andrew McPherson, Mikkael A. Sekeres, Alexander M Lesokhin, David J. Chung, Yanming Zhang, Caleb Ho, Mikhail Roshal, Jeffrey W. Tyner, Stephen D Nimer, Elli Papaemmanuil, Saad Usmani, Gareth J. Morgan, Ola Landgren, Francesco Maura
Journal: Blood
Blood (2022) 140 (Supplement 1): 2088–2090.
https://doi.org/10.1182/blood-2022-158992
Published: 2022
Journal Articles

Erythroid and Megakaryocytic Differentiation Program in JAK2 -Mutated Acute Myeloid Leukemia with or without Antecedent Myeloproliferative Neoplasm

Ying Liu, Shenon Sethi, Richard Koche, Qi Gao, Deepika Dilip, Jacob L Glass, Pallavi K Galera, Sonali Persaud, Tanmay Mishra, Xiaotian Sun, Dory Londono, Robert Cimera, Menglei Zhu, Christopher Famulare, Jeeyeon Baik, Himanshu Bhurtel, Maria E. Arcila, Ahmet Dogan, Ross L. Levine, Yanming Zhang, Mikhail Roshal, Raajit K Rampal, Wenbin Xiao
Journal: Blood
Blood (2022) 140 (Supplement 1): 9160–9162.
https://doi.org/10.1182/blood-2022-169215
Published: 2022
Journal Articles

Single Cell Genotypic and Phenotypic Analysis of Measurable Residual Disease in Acute Myeloid Leukemia

Troy Robinson, Robert L. Bowman, Sonali Persaud, Ying Liu, Qi Gao, Jing-Ping Zhang, Xiaotian Sun, Adam Sciambi, Aaron Llanso, Christopher Famulare, Aaron D Goldberg, Ahmet Dogan, Mikhail Roshal, Ross L. Levine, Wenbin Xiao
Journal: Blood
Blood (2022) 140 (Supplement 1): 2275–2277.
https://doi.org/10.1182/blood-2022-166501
Published: 2022
Journal Articles

High-Resolution Single Cell T-Cell Phenotyping of B-Cell Lineage Lymphomas Reveals Unique Immune Signatures and Potential Targetable Vulnerabilities

Sary El Daker, Jeeyeon Baik, Ahmet Dogan, Menglei Zhu, Mikhail Roshal, Pallavi K Galera
Journal: Blood
Blood (2022) 140 (Supplement 1): 3570–3572.
https://doi.org/10.1182/blood-2022-163543
Published: 2022
Journal Articles

Immune Escape after Allogeneic Hematopoietic Cell Transplantation in Pediatric Patients with Acute Myeloid Leukemia

Sanam Shahid, Nicholas Ceglia, Jean-Benoit Le Luduec, Andrew McPherson, Barbara Spitzer, Viktoria Bojilova, M. Kazim Panjwani, Mikhail Roshal, Sohrab Shah, Omar Abdel-Wahab, Benjamin Greenbaum, Katharine C. Hsu
Journal: Blood
Blood (2022) 140 (Supplement 1): 10209–10210.
https://doi.org/10.1182/blood-2022-162436
Published: 2022
Journal Articles

Stem Cell Autograft Minimal Residual Disease Negativity Improves Outcomes after Autotransplant for Multiple Myeloma

Noriko Nishimura, Samantha Brown, Sean M. Devlin, Parastoo B. Dahi, Heather Landau, Oscar B Lahoud, Michael Scordo, Gunjan L. Shah, Hani Hassoun, Malin Hultcrantz, Neha Korde, Alexander M Lesokhin, Sham Mailankody, Urvi A Shah, Carlyn Tan, Saad Usmani, Sergio A. Giralt, David J. Chung, Gaurav Gupta, Elena Maryamchik, Evangelos Ntrivalas, Mikhail Roshal
Journal: Blood
Blood (2022) 140 (Supplement 1): 620–622.
https://doi.org/10.1182/blood-2022-160271
Published: 2022
Journal Articles

Updated Survival and Response Analyses from a Phase 1 Study of Ivosidenib or Enasidenib Combined with Induction and Consolidation Chemotherapy in Patients with Newly Diagnosed AML with an IDH1 or IDH2 Mutation

Eytan M. Stein, Courtney D. DiNardo, Amir T. Fathi, Alice S. Mims, Michael R. Savona, Anthony S. Stein, Richard M. Stone, Eric S. Winer, Christopher S. Seet, Hartmut Döhner, Daniel A. Pollyea, James K McCloskey, Olatoyosi Odenike, Bob Lowenberg, Gert J. Ossenkoppele, Prapti Patel, Mikhail Roshal, Mark G. Frattini, Frederik Lersch, Salah Nabhan, Caroline Almon, Duygu Saatcioglu, Vickie Zhang, Michael Cooper, Hagop Kantarjian, Martin S. Tallman
Journal: Blood
Blood (2021) 138 (Supplement 1): 1276.
https://doi.org/10.1182/blood-2021-146507
Published: 2021
Journal Articles

Clinical and Genomic Characterization of Secondary Acute Myeloid Leukemia with Mixed Phenotype

Pallavi Galera, Alexander Chan, Andriy Derkach, Ying Liu, Jeeyeon Baik, Christopher Famulare, Allison Sigler, Maria E. Arcila, Douglas A Mata, Ahmet Dogan, Martin S. Tallman, Ross L. Levine, Yanming Zhang, Mikhail Roshal, Jacob L Glass, Wenbin Xiao
Journal: Blood
Blood (2021) 138 (Supplement 1): 687.
https://doi.org/10.1182/blood-2021-151263
Published: 2021
Journal Articles

Deep Phenotyping Reveals Expansion of T Follicular Regulatory Cells and Triple Positive (CTLA4, TIGIT, PD1) Exhausted Effector Memory T Cells Characterizing the Immunosuppressive Microenvironment in Follicular Lymphoma

Sary El Daker, Daniel Freeman, Jeeyeon Baik, Menglei Zhu, Pratip Chattopadhyay, Mikhail Roshal, Ahmet Dogan, Pallavi Galera
Journal: Blood
Blood (2021) 138 (Supplement 1): 3524.
https://doi.org/10.1182/blood-2021-153872
Published: 2021
Journal Articles

Chemotherapy-Related Mutational Signatures Reveal the Origins of Therapy-Related Myeloid Neoplasms

Benjamin Diamond, Bachisio Ziccheddu, Eileen M Boyle, Kylee H Maclachlan, Juan Arango Ossa, Justin Taylor, Justin Watts, Sydney X. Lu, Venkata D Yellapantula, Christopher Famulare, Monika Chojnacka, Arjun Raj Rajanna, Emilia Mason, David G. Coffey, James E. Hoffman, Dickran Kazandjian, Terrence J Bradley, Menglei Zhu, Niccolo Bolli, Elli Papaemmanuil, Kelly L. Bolton, Michael Scordo, Oscar B Lahoud, Eytan M. Stein, Craig S. Sauter, Hani Hassoun, Sham Mailankody, Neha Korde, Malin Hultcrantz, Urvi A Shah, Gunjan L Shah, Jae H Park, Heather J Landau, Karuna Ganesh, Mikkael A. Sekeres, Stephen Nimer, David J. Chung, Caleb Ho, Mikhail Roshal, Alexander Lesokhin, Gareth J. Morgan, Ola Landgren, Francesco Maura
Journal: Blood
Blood (2021) 138 (Supplement 1): 3271.
https://doi.org/10.1182/blood-2021-145927
Published: 2021
Journal Articles

Molecular Evolution of Classical Hodgkin Lymphoma Revealed Though Whole Genome Sequencing of Hodgkin and Reed-Sternberg Cells

Francesco Maura, Marcin Imielinski, Jenny Z Xiang, Bhavneet Binder, Kenneth Eng, Manik Uppal, Feng He, Wei Zhang, Qi Gao, Sunita I. Park, Matthew J. Oberley, Elizabeth Ruckdeschel, Megan S. Lim, Gerald Wertheim, Matthew J. Barth, Terzah M. Horton, Bachisio Ziccheddu, Federico Abascal, Kylee H Maclachlan, Venkata D Yellapantula, Ola Landgren, Craig H. Moskowitz, Ethel Cesarman, Mikhail Roshal, Olivier Elemento, Lisa Giulino Roth
Journal: Blood
Blood (2021) 138 (Supplement 1): 805.
https://doi.org/10.1182/blood-2021-148663
Published: 2021
Journal Articles

Phase I First-in-Class Trial of MCARH109, a G Protein Coupled Receptor Class C Group 5 Member D (GPRC5D) Targeted CAR T Cell Therapy in Patients with Relapsed or Refractory Multiple Myeloma

Sham Mailankody, Claudia Diamonte, Lisa Fitzgerald, Peter Kane, Xiuyan Wang, Devanjan S. Sikder, Brigitte Senechal, Vladimir P. Bermudez, Diana Frias, Justina Morgan, Patrick Grant, Terence J Purdon, Kinga Hosszu, Sean M Devlin, Urvi A Shah, Jonathan Landa, Alexander Lesokhin, Neha Korde, Hani Hassoun, Carlyn Tan, Malin Hultcrantz, Gunjan L. Shah, Heather J Landau, David J. Chung, Michael Scordo, Mikhail Roshal, Ola Landgren, Ahmet Dogan, Sergio A Giralt, Jae H Park, Isabelle Rivière, Renier J Brentjens, Eric L Smith
Journal: Blood
Blood (2021) 138 (Supplement 1): 827.
https://doi.org/10.1182/blood-2021-153204
Published: 2021
Journal Articles

Zanubrutinib, Obinutuzumab, and Venetoclax in Chronic Lymphocytic Leukemia: Early MRD Kinetics Define a High-Risk Patient Cohort with Delayed Bone Marrow Undetectable MRD and Earlier Post-Treatment MRD Recurrence

Jacob D. Soumerai, Anthony R. Mato, Ahmet Dogan, Venkatraman Seshan, Erel Joffe, Kelsey Flaherty, Jason Carter, Ephraim P Hochberg, Jeffrey A Barnes, Audrey Hamilton, Jeremy S. Abramson, Connie Lee Batlevi, Matthew J. Matasar, Ariela Noy, Colette Owens, M. Lia Palomba, Anita Kumar, Tak Takvorian, Ai Ni, Morgan Choma, Chaya Friedman, Puja Chadha, Elizabeth Simkins, Jade Ruiters, Sidney Sechio, Daneal Portman, Natascha Nolet, Neena Mahajan, Rosalba Martignetti, Joanna Mi, Krista J Scorsune, Julia M Lynch, Brianne McGree, Stephanie Y Hughes, Clare Grieve, Lindsey E. Roeker, Meghan C. Thompson, P. Connor Johnson, Mikhail Roshal, Jane Huang, Juliana M.L. Biondo, Jenny Qun Wu, Allison P. Jacob, Omar Abdel-Wahab, Andrew D. Zelenetz
Journal: Blood
Blood (2021) 138 (Supplement 1): 3753.
https://doi.org/10.1182/blood-2021-150961
Published: 2021
Journal Articles

HHV-6 in the Lymphoma Microenvironment: Both Chicken and Egg?

Genevieve M Crane, Dmitry Tychinin, Anton Karelin, Aleksandr Cherdintsev, Olga Kudryashova, Evgeniy Egorov, Sandrine Degryse, Nikita Kotlov, Alexander Bagaev, Joseph Casano, Jonathan Reichel, Lisa Giulino Roth, Mikhail Roshal, Sakellarios Zairis, Raul Rabadan, Olivier Elemento, Giorgio Inghirami, Ethel Cesarman
Journal: Blood
Blood (2021) 138 (Supplement 1): 1377.
https://doi.org/10.1182/blood-2021-146336
Published: 2021
Journal Articles

Interventions and outcomes of adult patients with B-ALL progressing after CD19 chimeric antigen receptor T-cell therapy

Clinical Trials & Observations
Kitsada Wudhikarn, Jessica R. Flynn, Isabelle Rivière, Mithat Gönen, Xiuyan Wang, Brigitte Senechal, Kevin J. Curran, Mikhail Roshal, Peter G. Maslak, Mark B. Geyer, Elizabeth F. Halton, Claudia Diamonte, Marco L. Davila, Michel Sadelain, Renier J. Brentjens, Jae H. Park
Journal: Blood
Blood (2021) 138 (7): 531–543.
https://doi.org/10.1182/blood.2020009515
Published: 2021
Includes: Supplemental data
Journal Articles

Ivosidenib or enasidenib combined with intensive chemotherapy in patients with newly diagnosed AML: a phase 1 study

Clinical Trials & Observations
Eytan M. Stein, Courtney D. DiNardo, Amir T. Fathi, Alice S. Mims, Keith W. Pratz, Michael R. Savona, Anthony S. Stein, Richard M. Stone, Eric S. Winer, Christopher S. Seet, Hartmut Döhner, Daniel A. Pollyea, James K. McCloskey, Olatoyosi Odenike, Bob Löwenberg, Gert J. Ossenkoppele, Prapti A. Patel, Mikhail Roshal, Mark G. Frattini, Frederik Lersch, Aleksandra Franovic, Salah Nabhan, Bin Fan, Sung Choe, Hongfang Wang, Bin Wu, Lei Hua, Caroline Almon, Michael Cooper, Hagop M. Kantarjian, Martin S. Tallman
Journal: Blood
Blood (2021) 137 (13): 1792–1803.
https://doi.org/10.1182/blood.2020007233
Published: 2021
Includes: Supplemental data