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Kelly L. Bolton
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Journal Articles

Impact of PARP Inhibitor and Platinum Therapy on Clonal Hematopoiesis

Jeremy T. Baeten, Irenaeus C.C. Chan, Lea Moukarzel, Amber C. Carter, Minal Patel, Konrad H. Stopsack, Paul Pharoah, James Brenton, Bob T Li, Wassim Abida, Alison M. Schram, Karen Cadoo, Britta Weigelt, Carlos Cruchaga, Howard Scher, Ross L Levine, Elli Papaemmanuil, Daniel C. Link, Kelly L. Bolton
Journal: Blood
Blood (2023) 142 (Supplement 1): 1315.
https://doi.org/10.1182/blood-2023-190457
Published: 2023
Journal Articles

Ivosidenib for Patients with Clonal Cytopenia of Undetermined Significance and Mutations in IDH1

Giulia Petrone, Eytan M. Stein, Kelly L. Bolton
Journal: Blood
Blood (2023) 142 (Supplement 1): 3253.
https://doi.org/10.1182/blood-2023-184977
Published: 2023
Journal Articles

Plasma Proteomic Signature Predicts Risk of Myeloid Neoplasm

J. Scott Beeler, Duc Tran, Jie Liu, Zilan Xin, Brian Wiley, Irenaeus C.C. Chan, Michael H. Kramer, Armel L. Batchi-Bouyou, Xiaoyu Zong, Matthew J. Walter, Sarantis Chlamydas, Francesca Ferraro, Stephen T. Oh, Ben Busby, Daniel C. Link, Yin Cao, Kelly L. Bolton
Journal: Blood
Blood (2023) 142 (Supplement 1): 940.
https://doi.org/10.1182/blood-2023-190857
Published: 2023
Journal Articles

Deconvoluting Clonal and Cellular Architecture in IDH -Mutant Acute Myeloid Leukemia

Maria Sirenko, Soobeom Lee, Zhengxi Sun, Ronan Chaligne, Georgios Asimomitis, Charlotte K Brierley, Elsa Bernard, Sheng F. Cai, Robert M Myers, Bettina Nadorp, Max F Levine, Dylan Domenico, Juan E Arango Ossa, Juan Santiago Medina Martinez, Kamal Menghrajani, Audrey Lasry, Alice Mims, Helee Desai, Andrea Laganson, Christopher Famulare, Minal Patel, Gerard Lozanski, Sanam Loghavi, Kelly L. Bolton, Aaron D. Viny, Mikhail Roshal, Ross L Levine, Eytan M. Stein, Dan A. Landau, Ann-Kathrin Eisfeld, Iannis Aifantis, Elli Papaemmanuil
Journal: Blood
Blood (2023) 142 (Supplement 1): 1591.
https://doi.org/10.1182/blood-2023-186322
Published: 2023
Journal Articles

Clonal Hematopoiesis Is Common in Unrelated Stem Cell Donors but Has No Impact on Patient Outcome after Hematopoietic Stem Cell Transplantation

Johannes Schetelig, Frederik Damm, Ulf - Peter Günther, Henning Baldauf, Carina Rave, Linda Koster, Gerhard Schöfl, Anja Klussmeier, Kamal Menghrajani, Kelly L. Bolton, Elke Rücker-Braun, Falk Heidenreich, Marie Münn, Markus Fuhrmann, Ilaria Visco, Mareike Frick, Raphael Hablesreiter, Christopher Maximilian Arends, Liesbeth C. de Wreede, Olena Nesterenko, Matthias Stelljes, Gesine Bug, Thomas Schröder, Ivan Sergeevich Moiseev, Helene Schoemans, Christian Koenecke, Raphael Teipel, Malte von Bonin, Lars Bullinger, Martin Bornhäuser, Marcel R.M. van den Brink, Alexander H. Schmidt, Vinzenz Lange, Zinaida Peric, Olaf Penack
Journal: Blood
Blood (2023) 142 (Supplement 1): 942.
https://doi.org/10.1182/blood-2023-179112
Published: 2023
Journal Articles

Genetic Determinants of Clonal Hematopoiesis and Progression to Hematologic Malignancies in 479,117 Individuals

Jie Liu, Duc Tran, Irenaeus C.C. Chan, Brian Wiley, Caroline Watson, Armel L. Batchi-Bouyou, Xiaoyu Zong, Konrad H. Stopsack, Paul Pharoah, Li Ding, Jamie R Blundell, Yin Cao, Matthew J. Walter, Nilanjan Chatterjee, Kenneth Offit, Lucy Godley, Daniel C. Link, Zsofia Stadler, Kelly L. Bolton
Journal: Blood
Blood (2023) 142 (Supplement 1): 811.
https://doi.org/10.1182/blood-2023-182423
Published: 2023
Journal Articles

Arcch: Improving the Performance of Clonal Hematopoiesis Variant Calling and Interpretation Using a Consensus Based Approach

Evelyn L Schmidt, Irenaeus C.C. Chan, Alex Panchot, Brian Wiley, Jie Liu, Lea Moukarzel, Yiwen Zhang, Daniel C. Link, Konrad Stopsack, Kelly L Bolton
Journal: Blood
Blood (2022) 140 (Supplement 1): 5762–5763.
https://doi.org/10.1182/blood-2022-170221
Published: 2022
Journal Articles

Tracking the Evolution of Therapy-Related Myeloid Neoplasms Using Chemotherapy Signatures

Bachisio Ziccheddu, Benjamin Diamond, Kylee H Maclachlan, Justin Taylor, Eileen M Boyle, Juan E. Arango Ossa, Jahn Jacob, Maurizio Affer, Tulasigeri M Totiger, David Coffey, Justin Watts, Sydney X. Lu, Niccolo Bolli, Kelly L Bolton, Jae H Park, Heather Landau, Karuna Ganesh, Andrew McPherson, Mikkael A. Sekeres, Alexander M Lesokhin, David J. Chung, Yanming Zhang, Caleb Ho, Mikhail Roshal, Jeffrey W. Tyner, Stephen D Nimer, Elli Papaemmanuil, Saad Usmani, Gareth J. Morgan, Ola Landgren, Francesco Maura
Journal: Blood
Blood (2022) 140 (Supplement 1): 2088–2090.
https://doi.org/10.1182/blood-2022-158992
Published: 2022
Journal Articles

Chemotherapy-Related Mutational Signatures Reveal the Origins of Therapy-Related Myeloid Neoplasms

Benjamin Diamond, Bachisio Ziccheddu, Eileen M Boyle, Kylee H Maclachlan, Juan Arango Ossa, Justin Taylor, Justin Watts, Sydney X. Lu, Venkata D Yellapantula, Christopher Famulare, Monika Chojnacka, Arjun Raj Rajanna, Emilia Mason, David G. Coffey, James E. Hoffman, Dickran Kazandjian, Terrence J Bradley, Menglei Zhu, Niccolo Bolli, Elli Papaemmanuil, Kelly L. Bolton, Michael Scordo, Oscar B Lahoud, Eytan M. Stein, Craig S. Sauter, Hani Hassoun, Sham Mailankody, Neha Korde, Malin Hultcrantz, Urvi A Shah, Gunjan L Shah, Jae H Park, Heather J Landau, Karuna Ganesh, Mikkael A. Sekeres, Stephen Nimer, David J. Chung, Caleb Ho, Mikhail Roshal, Alexander Lesokhin, Gareth J. Morgan, Ola Landgren, Francesco Maura
Journal: Blood
Blood (2021) 138 (Supplement 1): 3271.
https://doi.org/10.1182/blood-2021-145927
Published: 2021
Journal Articles

Clonal Hematopoiesis Is Associated with Risk of Cardiovascular Disease in Individuals with Human Immunodeficiency Virus

Brian Wiley, Kristin Erlandson, Katherine Tassiopoulos, Yizhe Song, Rachel Presti, Kelly L Bolton, Grant A. Challen
Journal: Blood
Blood (2021) 138 (Supplement 1): 3277.
https://doi.org/10.1182/blood-2021-151843
Published: 2021
Journal Articles

Effects of PARP Inhibitor Therapy on p53-Deficient Hematopoietic Stem and Progenitor Cell Fitness

Jeremy T Baeten, Irenaeus C.C. Chan, Daniel C. Link, Kelly L. Bolton
Journal: Blood
Blood (2021) 138 (Supplement 1): 3275.
https://doi.org/10.1182/blood-2021-151373
Published: 2021
Journal Articles

Genomic profiling identifies somatic mutations predicting thromboembolic risk in patients with solid tumors

Andrew Dunbar, Kelly L. Bolton, Sean M. Devlin, Francisco Sanchez-Vega, Jianjiong Gao, Jodi V. Mones, Jonathan Wills, Daniel Kelly, Mirko Farina, Keith B. Cordner, Young Park, Sirish Kishore, Krishna Juluru, Neil M. Iyengar, Ross L. Levine, Ahmet Zehir, Wungki Park, Alok A. Khorana, Gerald A. Soff, Simon Mantha
Journal: Blood
Blood (2021) 137 (15): 2103–2113.
https://doi.org/10.1182/blood.2020007488
Published: 2021
Includes: Supplemental data
Journal Articles

Interplay between Chromosomal Alterations and Gene Mutations Shapes the Evolutionary Trajectory of Clonal Hematopoiesis

Teng Gao, Ryan Ptashkin, MS, Kelly L. Bolton, MD PhD, Christopher Fong, PhD, Barbara Spitzer, MD, Kamal Menghrajani, MD, Juan E. Arango Ossa, BS, Yangyu Zhou, BS, Elsa Bernard, PhD, Max Levine, MS, Juan Medina, MS, Yanming Zhang, MD, Sebastià Franch-Expósito, PhD, Minal A Patel, MPH, Lior Braunstein, MD, Daniel Kelly, MS, Mariko Yabe, MD PhD, Ryma Benayed, PhD, Nicole M Caltabellotta, BA, John Philip, BA, MS, Ederlinda Paraiso, Simon Mantha, MDMPH, David B. Solit, MD, Luis Alberto Diaz, MD, Michael F. Berger, PhD, Virginia M. Klimek, MD, Ross L. Levine, MD, Ahmet Zehir, PhD, Sean Devlin, PhD, Elli Papaemmanuil, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 29–30.
https://doi.org/10.1182/blood-2020-141882
Published: 2020
Journal Articles

Germline Contributions to Clonal Hematopoiesis in Solid Cancer Patients

Sebastià Franch-Expósito, PhD, Preethi Srinivasan, PhD, Ryan Ptashkin, MS, Chaitanya Bandlamudi, PhD, Kelly L. Bolton, MD PhD, Erika Gedvilaite, Kamal Menghrajani, MD, Diana Mandelker, MD PhD, Elizabeth Comen, MD, Larry Norton, MD, Ryma Benayed, PhD, Teng Gao, Elli Papaemmanuil, PhD, Barry S Taylor, PhD, Ross L. Levine, MD, Michael F. Berger, PhD, Ahmet Zehir, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 30–31.
https://doi.org/10.1182/blood-2020-140868
Published: 2020
Journal Articles

Clonal Hematopoiesis and COVID-19 Severity in Cancer Patients

Kelly L. Bolton, MD PhD, Michael Foote, MD, Justin Jee, Anton Safonov, MD, Ryan Ptashkin, MS, Sean Devlin, PhD, Erika Gedvilaite, Teng Gao, Elli Papaemmanuil, PhD, Melissa S. Pessin, MD PhD, Mini Kamboj, Joseph Vijai, PhD, Kenneth Offit, MD, Phillip Awadalla, PhD, Pradeep Nataranjan, Michael F. Berger, PhD, Larry Norton, MD, Ross L. Levine, MD, Ahmet Zehir, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 37–38.
https://doi.org/10.1182/blood-2020-143041
Published: 2020
Journal Articles

Machine Learning for Prediction of Cancer-Associated Venous Thromboembolism

Simon Mantha, MDMPH, Andrew Dunbar, MD, Kelly L. Bolton, MD PhD, Sean Devlin, PhD, Dmitriy Gorenshteyn, PhD, Mark Donoghue, PhD, Maria E. Arcila, MD, Gerald A. Soff, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 37.
https://doi.org/10.1182/blood-2020-138579
Published: 2020
Journal Articles

What to tell your patient with clonal hematopoiesis and why: insights from 2 specialized clinics

David P. Steensma, Kelly L. Bolton
Journal: Blood
Blood (2020) 136 (14): 1623–1631.
https://doi.org/10.1182/blood.2019004291
Published: 2020
Includes: Supplemental data