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Journal Articles

Antigen escape as a shared mechanism of resistance to BCMA-directed therapies in multiple myeloma

Brief Report
Ross S. Firestone, Nicholas D. Socci, Tala Shekarkhand, Menglei Zhu, Wei Ge Qin, Malin Hultcrantz, Sham Mailankody, Carlyn Rose Tan, Neha Korde, Alexander M. Lesokhin, Hani Hassoun, Urvi Shah, Kylee H. Maclachlan, Sridevi Rajeeve, Heather J. Landau, Michael Scordo, Gunjan L. Shah, Oscar B. Lahoud, Sergio Giralt, Kazunori Murata, Saad Z. Usmani, David J. Chung
Journal: Blood
Blood (2024) 144 (4): 402–407.
https://doi.org/10.1182/blood.2023023557
Published: 2024
Includes: Supplemental data
Journal Articles

Engraftment Syndrome during Autologous Stem Cell Transplant in Hodgkin Lymphoma Patients Treated with Checkpoint Inhibitors: A Multi-Center Retrospective Analysis

Eleanor Taranto, Wei-Ting Hwang, Maria Alfaro, Annika S Surapaneni, Sarvarinder Kaur Gill, Tatyana Feldman, Michael P Randall, Michael A Spinner, Fateeha Furqan, Nirav N. Shah, Yazeed Samara, Matthew G. Mei, Alex F. Herrera, Alison Moskowitz, Gunjan L. Shah, Jakub Svoboda
Journal: Blood
Blood (2023) 142 (Supplement 1): 3603.
https://doi.org/10.1182/blood-2023-187199
Published: 2023
Journal Articles

Patterns of Cytokine Release Syndrome with Teclistamab in Relapsed/Refractory Multiple Myeloma with or without Prior T-Cell Redirection Therapy

Issam S. Hamadeh, Tala Shekarkhand, Colin Rueda, Ross Firestone, Alice Wang, Neha Korde, Malin Hultcrantz, Alexander Lesokhin, Sham Mailankody, Hani Hassoun, Urvi A Shah, Kylee H Maclachlan, Dhwani Patel, Gunjan L. Shah, Michael Scordo, Oscar Boutros Lahoud, David Chung, Heather Landau, Sergio A. Giralt, Saad Z Usmani, Carlyn Rose Tan
Journal: Blood
Blood (2023) 142 (Supplement 1): 1961.
https://doi.org/10.1182/blood-2023-180283
Published: 2023
Journal Articles

Evaluating the Effect of Evolving Changes in Serum Biomarkers on the Risk of Progression in Smoldering Multiple Myeloma

Theresia Akhlaghi, David Nemirovsky, Kylee H Maclachlan, Neha Korde, Sham Mailankody, Alexander Lesokhin, Hani Hassoun, Dhwani Patel, Urvi A Shah, Carlyn Tan, Oscar Boutros Lahoud, Heather Landau, Gunjan L. Shah, Michael Scordo, David Chung, Ola Landgren, Sergio A. Giralt, Saad Z Usmani, Andriy Derkach, Malin Hultcrantz
Journal: Blood
Blood (2023) 142 (Supplement 1): 877.
https://doi.org/10.1182/blood-2023-180315
Published: 2023
Journal Articles

From Widespread to Tailored Antifungal Prophylaxis in Lymphoma Patients Treated with CD19 CAR T- Cell Therapy: Less Is Better

Giovanna Melica, Alejandro Luna De Abia, Magdalena Corona, Joshua Fein, Parastoo B Dahi, Sergio A. Giralt, Ivan Landego, Richard J. Lin, Maria Lia Palomba, Allison Parascondola, Jae H. Park, Gilles Salles, Amethyst Saldia, Michael Scordo, Ana Alarcon Tomas, Gunjan L. Shah, Roni Shouval, Ying Taur, Miguel-Angel Perales, Susan K. Seo
Journal: Blood
Blood (2023) 142 (Supplement 1): 3514.
https://doi.org/10.1182/blood-2023-181997
Published: 2023
Journal Articles

Impact of Response to Systemic Bridging Therapy on Clinical Outcomes and Cytokine Profiles in Patients Receiving CD19- CAR T-Cell Therapy for B-Cell Lymphoma

Beatriz Wills, Roni Shouval, Jessica R. Flynn, Sean M. Devlin, Allison Parascondola, Amethyst Saldia, Brandon S. Imber, Ana Alarcon Tomas, Ivan Landego, Richard J. Lin, Michael Scordo, Parastoo Bahrami Dahi, Gunjan L. Shah, Andrew Ip, Lori A Leslie, Hyung Chan Suh, Gilles Salles, Miguel-Angel Perales, Maria Lia Palomba
Journal: Blood
Blood (2023) 142 (Supplement 1): 3014.
https://doi.org/10.1182/blood-2023-181116
Published: 2023
Journal Articles

Low Target Antigen Expression Mediates Resistance to BCMA CAR T Cell Therapy

Karlo Perica, Sarah Nataraj, Maria Lemdal Sjojstrand, Katherine Nagel, Emma Pavkovic, Erica Payson, Ana Cuenca, Anjali Patel, David Chung, Sham Mailankody, Gunjan L. Shah, Saad Z Usmani, Sergio A. Giralt, Michel Sadelain
Journal: Blood
Blood (2023) 142 (Supplement 1): 2124.
https://doi.org/10.1182/blood-2023-178954
Published: 2023
Journal Articles

CNS Radiotherapy As Bridging Prior to CAR T-Cell Therapy for Non-Hodgkin B-Cell Lymphoma

Gustav Cederquist, Javin Schefflein, Sean M. Devlin, Harper Hubbeling, Kathryn Tringale, Gunjan L. Shah, Ana Alarcon Tomas, Roni Shouval, Carla Hajj, Beatrice Fregonese, Parastoo B. Dahi, Richard J. Lin, Maria Lia Palomba, Miguel-Angel Perales, Gilles Salles, Lorenzo Falchi, Christian Grommes, Michael Scordo, Joachim Yahalom, Brandon S. Imber
Journal: Blood
Blood (2023) 142 (Supplement 1): 4491.
https://doi.org/10.1182/blood-2023-190326
Published: 2023
Journal Articles

Responses and Outcomes after Second-Line Therapy in Transplant-Eligible Patients with DLBCL Relapse over 1 Year after First-Line Therapy

David A Qualls, Gunjan L. Shah, Roni Shouval, Philip Caron, Kevin A. David, Lorenzo Falchi, Paola Ghione, Paul A. Hamlin, Steven M. Horwitz, Andrew M. Intlekofer, William Johnson, Anita Kumar, Oscar Boutros Lahoud, Jennifer Kimberly Lue, Alison Moskowitz, Ariela Noy, Maria Lia Palomba, Pallawi Torka, Santosha A Vardhana, Andrew D. Zelenetz, Michelle Okwali, Parastoo Bahrami Dahi, Michael Scordo, Richard J. Lin, Miguel-Angel Perales, Gilles Salles
Journal: Blood
Blood (2023) 142 (Supplement 1): 4970.
https://doi.org/10.1182/blood-2023-182733
Published: 2023
Journal Articles

Comparison of Bendamustine Versus Fludarabine/ Cyclophosphamide Lymphodepletion in Adult Patients Receiving CD19 CAR-T Cell Therapy

Ivan Landego, David Nemirovsky, Sean M. Devlin, Beatriz Wills, Allison Parascondola, Amethyst Saldia, Parastoo B. Dahi, Ana Alarcon Tomas, Andrew Ip, Hyung C Suh, Lori A. Leslie, Karthik Nath, Sergio A. Giralt, Richard J. Lin, Maria Lia Palomba, Gilles Salles, Gunjan L. Shah, Roni Shouval, Miguel-Angel Perales, Michael Scordo
Journal: Blood
Blood (2023) 142 (Supplement 1): 3510.
https://doi.org/10.1182/blood-2023-189349
Published: 2023
Journal Articles

Dynamics of Radiomic Features Following Bridging Therapy Determine CD19 Chimeric Antigen Receptor (CAR) T-Cell Therapy Outcome

Harper Hubbeling, Doris Leithner, Emily A. Silverman, Jessica R. Flynn, Sean M. Devlin, Gunjan L. Shah, Beatrice Fregonese, Akshay Bedmutha, Beatriz Wills, Ana Alarcon Tomas, Allison Parascondola, Amethyst Saldia, Ivan Landego, Parastoo B. Dahi, Sergio A. Giralt, Richard J. Lin, Michael Scordo, Gilles Salles, Joachim Yahalom, Maria Lia Palomba, Heiko Schoder, Miguel-Angel Perales, Roni Shouval, Brandon S. Imber
Journal: Blood
Blood (2023) 142 (Supplement 1): 2123.
https://doi.org/10.1182/blood-2023-187763
Published: 2023
Journal Articles

Evaluating Tumor-Intrinsic and Patient-Specific Mechanisms of Resistance to Teclistamab in Anti-BCMA Exposed and Naïve Multiple Myeloma

Ross Firestone, Devin McAvoy, Tala Shekarkhand, Edith Serrano, Issam S. Hamadeh, Alice Wang, Menglei Zhu, Dhwani Patel, Carlyn Tan, Malin Hultcrantz, Sham Mailankody, Hani Hassoun, Urvi A Shah, Neha Korde, Kylee H Maclachlan, Heather Landau, Michael Scordo, Gunjan L. Shah, Oscar Boutros Lahoud, Sergio A. Giralt, Kinga K Hosszu, David Chung, Alexander Lesokhin, Saad Z Usmani
Journal: Blood
Blood (2023) 142 (Supplement 1): 333.
https://doi.org/10.1182/blood-2023-187467
Published: 2023
Journal Articles

Identifying Causes of Unscheduled Healthcare Interactions and Changes to Patient Disposition in Individuals Receiving Outpatient Commercial Bispecific Antibody Therapy in Relapsed/Refractory Multiple Myeloma (RRMM)

Anna J Howard, Tala Shekarkhand, Issam S. Hamadeh, Alice Wang, Dhwani Patel, Carlyn Tan, Malin Hultcrantz, Sham Mailankody, Hani Hassoun, Urvi A Shah, Neha Korde, Kylee H Maclachlan, Heather Landau, Michael Scordo, Gunjan L. Shah, Oscar Boutros Lahoud, Sergio A. Giralt, David Chung, Alexander Lesokhin, Saad Z Usmani, Ross Firestone
Journal: Blood
Blood (2023) 142 (Supplement 1): 3707.
https://doi.org/10.1182/blood-2023-187889
Published: 2023
Journal Articles

Clinical Outcomes Associated with Del(17p) in Newly Diagnosed Multiple Myeloma Treated with Triplet and Daratumumab-Based Quadruplet Induction Regimens

Eric Jurgens, Ross Firestone, Kylee H Maclachlan, David Nemirovsky, Andriy Derkach, Malin Hultcrantz, Hani Hassoun, Sham Mailankody, Urvi A Shah, Sridevi Rajeeve, Dhwani Patel, Tala Shekarkhand, Colin Rueda, Yanming Zhang, Oscar Boutros Lahoud, Gunjan L. Shah, Michael Scordo, David Chung, Heather Landau, Sergio A. Giralt, Alexander Lesokhin, Neha Korde, Saad Z Usmani, Carlyn Tan
Journal: Blood
Blood (2023) 142 (Supplement 1): 2024.
https://doi.org/10.1182/blood-2023-190728
Published: 2023
Journal Articles

PD-1 Blockade before Autologous Stem Cell Transplantation Improves Outcomes in Relapsed/Refractory Classic Hodgkin Lymphoma: Results from a Multicenter Cohort

Sanjal H. Desai, Reid W. Merryman, Harsh Shah, Levi D. Pederson, Susan M. Geyer, Nivetha Ganesan, Tiffany Chang, Tamer Othman, Ayo S Falade, Gunjan L. Shah, Urshila Durani, Kelsey Baron, Shin Yeu Ong, Steve M Ansell, Philippe Armand, Siddharth Iyengar, Ivana Micallef, Alison Moskowitz, Alex F. Herrera, Robert Stuver, Matthew Genyeh Mei
Journal: Blood
Blood (2023) 142 (Supplement 1): 182.
https://doi.org/10.1182/blood-2023-179573
Published: 2023
Journal Articles

Pilot Study of Longitudinal Geriatric Assessment and Neurocognitive Evaluation in CAR T-Cell Therapy for Older Patients with Relapsed Refractory, Large B-Cell Lymphoma

Richard J. Lin, Soo Jung Kim, Denise Correa, Theresa A Elko, Stephanie Lobaugh, Raymond Baser, Adrian Koch, Danielle M Hanley, M. Lia Palomba, Parastoo B. Dahi, Michael Scordo, Gunjan L. Shah, Craig S Sauter, Katherine Nagel, Danielle Engstler, Nicole Lee, Emma Pavkovic, Jae H. Park, Miguel-Angel Perales, Sean M. Devlin, Beatriz Korc-Grodzicki, Paul A. Hamlin, Sergio A. Giralt
Journal: Blood
Blood (2023) 142 (Supplement 1): 7406.
https://doi.org/10.1182/blood-2023-190497
Published: 2023
Journal Articles

Higher CD4+ T Cell Counts after CAR-T in Large B-Cell Lymphomas Are Significantly Associated with Better Overall Survival

Danny Luan, Roni Shouval, Teng Fei, Efrat Luttwak, Alejandro Luna, Magdalena Corona, Maria Lia Palomba, Allison Parascondola, Michael Scordo, Gunjan L. Shah, Susan DeWolf, Miguel-Angel Perales
Journal: Blood
Blood (2023) 142 (Supplement 1): 4812.
https://doi.org/10.1182/blood-2023-184909
Published: 2023
Journal Articles

Artificial Intelligence Enabled ECG Interpretation Informs Outcomes after Autologous Transplantation for Multiple Myeloma

Brian C. Shaffer, Itzhak Zachi Attia, Grace Greason, Stephanie Chinapen, Samantha Brown, David Chung, Oscar Boutros Lahoud, Francisco Lopez-Jimenez, Wendy Schaffer, Jennifer Liu, Sergio A. Giralt, Gunjan L. Shah, Heather Landau, Saad Z Usmani, Paul A Friedman, Bernard J Gersh, Peter Noseworthy, Ioanna Kosmidou
Journal: Blood
Blood (2023) 142 (Supplement 1): 4965.
https://doi.org/10.1182/blood-2023-184725
Published: 2023
Journal Articles

Comprehensive Genomic Characterization of Response and Resistance to Daratumumab-Based Quadruplet Induction in Newly Diagnosed Multiple Myeloma Patients

Kylee H Maclachlan, Carlyn Rose Tan, Tala Shekarkhand, Colin Rueda, Edith Serrano, David Nemirovsky, Andriy Derkach, Andrew McPherson, Benjamin Diamond, Bachisio Ziccheddu, Eileen Boyle, Hani Hassoun, Sham Mailankody, Urvi A Shah, Malin Hultcrantz, Sergio A. Giralt, David Chung, Heather Landau, Oscar Boutros Lahoud, Michael Scordo, Gunjan L. Shah, Yanming Zhang, Robert Cimera, Maria E. Arcila, Ahmet Dogan, Alexander Lesokhin, Gareth J. Morgan, Ola Landgren, Francesco Maura, Neha Korde, Saad Z Usmani
Journal: Blood
Blood (2023) 142 (Supplement 1): 3370.
https://doi.org/10.1182/blood-2023-187891
Published: 2023
Journal Articles

T-Cell Exhaustion Signature Predicts Early Relapse after Autologous Stem Cell Transplant for Multiple Myeloma: BMT CTN 0702 Secondary Immune Analysis

Nezar Mehanna, Andriy Derkach, Billel Gasmi, Theodora Anagnostou, Heather Landau, Oscar Boutros Lahoud, Michael Scordo, Gunjan L. Shah, Hani Hassoun, Kylee H Maclachlan, Malin Hultcrantz, Neha Korde, Sham Mailankody, Urvi A Shah, Carlyn Rose Tan, Saad Z Usmani, Sergio A. Giralt, Alexander Lesokhin, David Chung
Journal: Blood
Blood (2023) 142 (Supplement 1): 3326.
https://doi.org/10.1182/blood-2023-177960
Published: 2023