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Juan-Jose Garces
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Journal Articles

Biological and Clinical Significance of Undetectable Circulating Tumor Cells (CTCs) in Patients (Pts) with Multiple Myeloma (MM)

Juan-José Garcés, Rosalinda Termini, Esperanza Martín-Sánchez, Marta Lasa, Jose J Perez, Norma C. Gutierrez, Manuela Fernández, Maria Jose Calasanz, Laura Rosiñol, Miguel Teodoro Hernández Garcia, Albert Oriol, Anna Maria Sureda Balari, Albert Perez Montaña, Enrique M Ocio, Maria Casanova Espinosa, Felipe Prosper, Joaquin Martinez-Lopez, Jorge Labrador, Esther Gonzalez Garcia, Rafael Ríos, Fernando Escalante, Joan Bargay, Elena Cabezudo, Valentín Cabañas, Niels Weinhold, Aldo Roccaro, Herve Avet-Loiseau, Alberto Orfao, Joan Blade Creixenti, Maria Victoria Mateos, Juan Jose Lahuerta Palacios, Jesus San-Miguel, María T Cedena, Noemi Puig, Bruno Paiva
Journal: Blood
Blood (2023) 142 (Supplement 1): 646.
https://doi.org/10.1182/blood-2023-186411
Published: 2023
Journal Articles

Kinetics and Biology of Circulating Tumor Cells (CTCs) and Measurable Residual Disease (MRD): Two Dynamic High-Risk Clones in Multiple Myeloma (MM)

Camila Guerrero, Rosalinda Termini, Juan-José Garcés, Maria Jose Calasanz, Rafael Ríos, Elena Cabezudo, Laura Rosiñol, Bargay Joan, Albert Pérez-Montaña, Albert Oriol Rocafiguera, Valentin Cabanas Perianes, Maria-Josefa Najera, Esther Gonzalez Garcia, Enrique M Ocio, Anna Maria Sureda Balari, Felipe De Arriba, Miguel Teodoro Hernández Garcia, Antonio Garcia, Joaquin Martinez-Lopez, María-Jesús Blanchard, Marta Sonia Gonzalez Perez, Rebeca Iglesias, Alberto Orfao, Maria Victoria Mateos, Juan Jose Lahuerta Palacios, Joan Bladé, Jesus San-Miguel, María T Cedena, Noemi Puig, Bruno Paiva
Journal: Blood
Blood (2023) 142 (Supplement 1): 871.
https://doi.org/10.1182/blood-2023-185661
Published: 2023
Journal Articles

Transcriptional and Genomic Characterization of Measurable Residual Disease (MRD) Cells in Acute Myeloid Leukemia (AML)

Catia Patricia Simoes, Sara Villar, Beñat Ariceta, Juan-José Garcés, Leire Burgos, Diego Alignani, Sarvide Sarai, David Martinez-Cuadron, Juan Miguel Bergua Burgués, Susana Vives, Lorenzo Algarra, Mar Tormo, Pilar Martinez Sanchez, Josefina Serrano, Pilar Herrera, Fernando Ramos, Olga Salamero, Esperanza Lavilla, Cristina Gil, Jose Luiz Lopez Lorenzo, María Belén Vidriales, María Carmen Chillón Santos, Jorge Labrador, José F. Falantes, Maria Jose Sayas, Rosa Ayala, Joaquín Martínez-López, Ana Alfonso-Pierola, María José Calasanz, Felipe Prosper, Jesús San-Miguel, Miguel A. Sanz, Pau Montesinos, Bruno Paiva
Journal: Blood
Blood (2022) 140 (Supplement 1): 2270–2272.
https://doi.org/10.1182/blood-2022-163159
Published: 2022
Journal Articles

Circulating Tumor Cells (CTCs) in Smoldering and Active Multiple Myeloma (MM): Mechanism of Egression, Clinical Significance and Therapeutic Endpoints

Juan-José Garcés, Noemi Puig, Rosalinda Termini, María Teresa Cedena, Cristina Moreno, José J Pérez, Diego Alignani, Sarvide Sarai, Albert Oriol, Esther González Garcia, Fernando Escalante, Anna Sureda, Felipe De Arriba, Rafael Rios, Jose Maria Moraleda, Mercedes Gironella, Miguel T Hernández, Juan Jose Joan Bargay, Luis Palomera, Alberto Orfao, Evangelos Terpos, Albert Pérez, Tomas Jelinek, Alexia Suárez, Hartmut Goldschmidt, Hervé Avet-Loiseau, Aldo M. Roccaro, Joaquin Martinez-Lopez, Juan Jose Lahuerta, Enrique Ocio, Laura Rosinol, Joan Bladé Creixenti, Maria-Victoria Mateos, Jesus San-Miguel, Bruno Paiva
Journal: Blood
Blood (2021) 138 (Supplement 1): 76.
https://doi.org/10.1182/blood-2021-146535
Published: 2021
Journal Articles

A Machine Learning Model Based on Tumor and Immune Biomarkers to Predict Undetectable Measurable Residual Disease (MRD) in Transplant-Eligible Multiple Myeloma (MM)

Camila Guerrero, Noemi Puig, María Teresa Cedena, Ibai Goicoechea, Cristina Pérez Ruiz, Juan José Garcés, Cirino Botta, Maria Jose Calasanz, Norma C. Gutierrez, Maria Luisa Martin-Ramos, Albert Oriol, Rafael Rios, Miguel Hernández, Rafael Martínez, Joan Bargay, Felipe De Arriba, Luis Palomera, Ana Pilar Gonzalez, Adrián Mosquera Orgueira, Marta Sonia Gonzalez, Joaquín Martínez-López, Juan Jose Lahuerta, Laura Rosinol, Joan Bladé Creixenti, Maria-Victoria Mateos, Jesus San-Miguel, Bruno Paiva
Journal: Blood
Blood (2021) 138 (Supplement 1): 1596.
https://doi.org/10.1182/blood-2021-145968
Published: 2021
Journal Articles

Deep MRD profiling defines outcome and unveils different modes of treatment resistance in standard- and high-risk myeloma

Clinical Trials & Observations
Ibai Goicoechea, Noemi Puig, Maria-Teresa Cedena, Leire Burgos, Lourdes Cordón, María-Belén Vidriales, Juan Flores-Montero, Norma C. Gutierrez, Maria-Jose Calasanz, Maria-Luisa Martin Ramos, David Lara-Astiaso, Amaia Vilas-Zornoza, Diego Alignani, Idoia Rodriguez, Sarai Sarvide, Daniel Alameda, Juan José Garcés, Sara Rodriguez, Vicente Fresquet, Jon Celay, Ramón Garcia-Sanz, Joaquin Martinez-Lopez, Albert Oriol, Rafael Rios, Jesus Martin-Sanchez, Rafael Martinez-Martinez, Josep Sarra, Miguel-Teodoro Hernandez, Javier de la Rubia, Isabel Krsnik, Jose-Maria Moraleda, Luis Palomera, Joan Bargay, Jose-Angel Martinez-Climent, Alberto Orfao, Laura Rosiñol, Maria-Victoria Mateos, Juan-José Lahuerta, Joan Blade, Jesús San Miguel, Bruno Paiva
Journal: Blood
Blood (2021) 137 (1): 49–60.
https://doi.org/10.1182/blood.2020006731
Published: 2021
Includes: Supplemental data
Journal Articles

Waldenström's Macroglobulinemia (WM) Is Preceded By Clonal Lymphopoiesis Including MYD88 L265P in Progenitor B Cells

Sara Rodríguez, PhD, Cirino Botta, MDPhD, Jon Celay, PhD, Ibai Goicoechea, PhD, Cristina Jiménez, PhD, Maria J Garcia-Barchino, PhD, Rafael Valdés-Mas, Yolanda Carrasco, Juan José Garcés, Marta Larrayoz, PhD, Susana Santos, Diego Alignani, PhD, Amaia Vilas-Zornoza, PhD, Cristina Pérez Ruiz, Sonia Garate, Sarvide Sarai, Aitziber Lopez Lopez, Christian Reinhardt, MD, Isidro Sanchez-Garcia, PhD, Maria Jose Larrayoz, BSc, María José Calasanz, PhD, Felipe Prosper, MD, Marina Motta, MD, Giuseppe Rossi, MD, Antonio Sacco, RN, Massimo Gentile, Sara Duarte, Helena Vitoria, Catarina Geraldes, MD PhD, Artur Paiva, Ramón Garcia-Sanz, MD PhD, Aldo M. Roccaro, MDPhD, Jesus F. San-Miguel, MD PhD, Jose Angel Martinez-Climent, MD PhD, Bruno Paiva, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 42–43.
https://doi.org/10.1182/blood-2020-136982
Published: 2020
Journal Articles

Discordances between Immunofixation (IFx) and Minimal Residual Disease (MRD) Assessment with Next-Generation Flow (NGF) and Sequencing (NGS) in Patients (Pts) with Multiple Myeloma (MM): Clinical and Pathogenic Significance

Sara Rodríguez, PhD, Ibai Goicoechea, PhD, Katerina Gemenetzi, Cirino Botta, MDPhD, Andreas Agathangelidis, PhD, Noemi Puig, MD PhD, María Teresa Cedena, MD, Alejandro Medina, MD, Rafael Valdés-Mas, Juan José Garcés, José J Pérez, Leire Burgos, María José Calasanz, PhD, Diego Alignani, PhD, Amaia Vilas-Zornoza, PhD, Sarvide Sarai, Felipe Prosper, MD, Jose Angel Martinez-Climent, MD PhD, Alberto Orfao, MD PhD, Ramón García-Sanz, MD PhD, Ana Jiménez Ubieto, MDPhD, Joaquin Martinez Lopez, Juan Jose Lahuerta, MD PhD, Laura Rosinol, MD PhD, Joan Bladé, MD PhD, María-Victoria Mateos, MD PhD, Anastasia Chatzidimitriou, Jesus F. San-Miguel, MD PhD, Bruno Paiva, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 5–6.
https://doi.org/10.1182/blood-2020-136258
Published: 2020
Journal Articles

Immunologic Characterization of Coronavirus Disease 2019 (COVID-19) Patients with Hematological Cancer: Biologic and Clinical Significance

Catarina Maia, Esperanza Martín-Sánchez, Juan José Garcés, Ascensión López-Diaz de Cerio, Susana Inogés, MD PhD, Manuel Landecho, Belen Gil-Alzugaray, Cristina Pérez Ruiz, Cirino Botta, MDPhD, Aintzane Zabaleta, PhD, Felix Alegre, MD, César Rincón, Laura Blanco, Sarai Sarvide, Amaia Vilas-Zornoza, PhD, Diego Alignani, PhD, Cristina Moreno, Monica Olid, Andrés Blanco, Josepmaria Argemi, Bruno Paiva, PhD, Jose-Ramon Yuste
Journal: Blood
Blood (2020) 136 (Supplement 1): 22–23.
https://doi.org/10.1182/blood-2020-136969
Published: 2020
Journal Articles

The Pathogenesis of Multiple Myeloma (MM) Is Preceded By Mutated Lymphopoiesis and B Cell Oligoclonality That Persist in Patients with Negative Minimal Residual Disease (MRD)

Sara Rodríguez, PhD, Noemi Puig, MD PhD, Katerina Gemenetzi, Ibai Goicoechea, PhD, Cirino Botta, MD, Andreas Agathangelidis, PhD, Rafael Valdés-Mas, Juan José Garcés, María Teresa Cedena, José J Pérez, Leire Burgos, Maria Jose Calasanz, PhD BSc, Diego Alignani, PhD, Amaia Vilas-Zornoza, PhD, Erika Lorenzo-Vivas, PhD, Irene Aires, Idoia Rodriguez, Sarvide Sarai, Felipe Prosper, MD PhD, Jose Angel Martinez-Climent, MD PhD, Alberto Orfao, MD PhD, Ramón García-Sanz, MD PhD, Joaquin Martinez-Lopez, MD PhD, Juan-José Lahuerta, MD PhD, Laura Rosinol Dachs, Joan Bladé, MD, Maria-Victoria Mateos, Anastasia Hadzidimitriou, PhD, Jesús San-Miguel, Bruno Paiva, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 509.
https://doi.org/10.1182/blood-2019-128049
Published: 2019
Journal Articles

Waldenström's Macroglobulinemia (WM) Is Preceded By Clonal Lymphopoiesis Including MYD88 L265P in Progenitor B Cells

Sara Rodríguez, PhD, Cirino Botta, MD, Jon Celay, PhD, Ibai Goicoechea, PhD, Maria J Garcia-Barchino, PhD, Rafael Valdés-Mas, Yolanda Carrasco, Daniel Alameda, PhD, Juan José Garcés, Marta Larrayoz, PhD, Susana Santos, Diego Alignani, PhD, Amaia Vilas-Zornoza, PhD, Erika Lorenzo-Vivas, PhD, Cristina Pérez Ruiz, Sonia Garate, Sarvide Sarai, Amaia Gascue, Christian Reinhardt, MD, Isidro Sanchez-Garcia, PhD, Maria Jose Larrayoz, PhD, Maria Jose Calasanz, PhD BSc, Felipe Prosper, MD PhD, Marina Motta, Antonella Anastasia, Antonio Sacco, RN, Massimo Gentile, Sara Duarte, Helena Vitoria, Catarina Geraldes, MD PhD, Artur Paiva, Aldo M. Roccaro, MD PhD, Jesús San-Miguel, Jose Angel Martinez-Climent, MD PhD, Bruno Paiva, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1527.
https://doi.org/10.1182/blood-2019-126889
Published: 2019
Journal Articles

Circulating Tumor Cells (CTCs) for Comprehensive and Multiregional Non-Invasive Genetic Characterization of Multiple Myeloma (MM)

Juan José Garcés, Gabriel Bretones, Leire Burgos, Rafael Valdes-Mas, Diego Alignani, PhD, Diana Álvarez Puente, Ibai Goicoechea, PhD, Miguel García Álvarez, Sonia Garate, Idoia Rodriguez, Maria Jose Calasanz, PhD BSc, Paula Rodriguez, MD, Rafael Rios, MD PhD, Joaquin Martinez-Lopez, MD PhD, Pamela Millacoy, Luis Palomera, MD PhD, Rafael Del Orbe, MD PhD, Albert Pérez, MD, Xabier Agirre, PhD, Juan Flores-Montero, Luzalba Sanoja-Flores, Alberto Orfao, MD PhD, Halima El Omri, Felipe Prosper, MD PhD, Carlos Lopez-Otin, Jesús San-Miguel, Bruno Paiva, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3064.
https://doi.org/10.1182/blood-2019-126527
Published: 2019
Journal Articles

Flowct: A Semi-Automated Workflow for Deconvolution of Immunophenotypic Data and Objective Reporting on Large Datasets

Cirino Botta, MD, Catarina Maia, Cristina Pérez Ruiz, Irene Manrique, Juan José Garcés, Sara Rodríguez, PhD, Leire Burgos, Juana Merino, Aitziber Lopez Lopez, Noemi Puig, MD PhD, María Teresa Cedena, Artur Paiva, Marco Rossi, Pierosandro Tagliaferri, MD, Piefrancesco Tassone, MD, Massimo Gentile, MD, Ivan M. Borrello, MD, Laura Rosinol Dachs, Maria-Victoria Mateos, MD PhD, Juan-José Lahuerta, MD PhD, Joan Bladé, MD, Jesús San-Miguel, Bruno Paiva, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4355.
https://doi.org/10.1182/blood-2019-122088
Published: 2019
Journal Articles

Transcriptomic Profiling of Circulating Tumor Cells (CTCs) in Multiple Myeloma (MM): A New Model to Understand Disease Dissemination

Juan José Garcés, Michal Šimíček, Marco Vicari, Lucie Brozova, MSc, Leire Burgos, Renata Bezděková, MSc., Diego Alignani, PhD, Maria Jose Calasanz, BSc, PhD, Katerina Growkova, Ludek Pour, MD, Rafael Rios, MD PhD, Joaquin Martinez-Lopez, MD PhD, Pamela Millacoy, Luis Palomera, MD PhD, Rafael Del Orbe, Sonia Garate, Laura Blanco, Patricia Maiso, PhD, Zuzana Chyra, Alexander Vdovin, Tomas Jelinek, Cirino Botta, MD, Halima El Omri, Xabier Agirre, PhD, Felipe Prosper, MD PhD, Roman Hajek, MD PhD, Jesus F San-Miguel, MD PhD, Bruno Paiva, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 245.
https://doi.org/10.1182/blood-2018-99-113331
Published: 2018
Journal Articles

Non-Invasive Genetic Profiling Is Highly Applicable in Multiple Myeloma (MM) through Characterization of Circulating Tumor Cells (CTCs)

Leire Burgos, Diego Alignani, Juan-Jose Garces, Lourdes Ortiz, Tomas Jelinek, MD, Victor Segura, PhD, Luzalba Sanoja, Maria-Jose Calasanz, Xabier Agirre, PhD, Felipe Prosper, MD, Paula Rodriguez-Otero, MD PhD, Rafael Rios, Joaquin Martinez-Lopez, Luis Palomera, MD PhD, Maria Teresa Zudaire, Rafael Del Orbe, MD, Jacques J.M. van Dongen, MD PhD, Alberto Orfao, MD PhD, Bruno Paiva, PhD, Jesus San Miguel, MD PhD
Journal: Blood
Blood (2016) 128 (22): 801.
https://doi.org/10.1182/blood.V128.22.801.801
Published: 2016