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Sarai Sarvide
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Journal Articles

A Multi-Omic Study Unveils a Clonal Population of TET2-Mutated Infiltrating T-Cells in Germinal Center B Cell Lymphomas (DLBCL and FL)

Sofia Huerga, Beñat Ariceta, Paula Aguirre-Ruiz, Patxi San-Martin, Sarai Sarvide, Marta Abengozar-Muela, Diego Alignani, Rocio Figueroa, Carlos Grande, Alvaro Lopez-Janeiro, Emma Muiños-Lopez, Juan Roberto Rodriguez-Madoz, Amaia Vilas-Zornoza, Felipe Prosper, Miguel Canales
Journal: Blood
Blood (2023) 142 (Supplement 1): 3003.
https://doi.org/10.1182/blood-2023-182830
Published: 2023
Journal Articles

Multiomics Characterization of Normal CD34+ Hematopoietic Progenitor Cells (HPC) and Blasts in the Bone Marrow (BM) and Peripheral Blood (PB) of Patients with Acute Myeloid Leukemia (AML)

Catia Simoes, Carmen Gonzalez, Leire Burgos, Sarai Sarvide, Diego Alignani, Aitziber Lopez, Ivan Quispe, Jose A. Pérez-Simón, María García-Fortes, Teresa Bernal Del Castillo, Mercedes Colorado, Teresa Olave, Ana Alfonso Pierola, Felipe Prosper, Pau Montesinos, Bruno Paiva
Journal: Blood
Blood (2023) 142 (Supplement 1): 2951.
https://doi.org/10.1182/blood-2023-185760
Published: 2023
Journal Articles

Combined Single-Cell and Spatial Transcriptomics Unveil the Complex Organization of the Non-Immune Human Bone Marrow Microenvironment during Aging

Itziar Cenzano, Miguel Cocera, Robert Lehmann, Jin Ye, Amaia Vilas-Zornoza, Patxi San-Martin, Paula Aguirre-Ruiz, Diego Alignani, Aitziber Lopez, Bruno Paiva, Marta Miñana Barrios, Ignacio Sancho Gonzalez, Javier Ruiz, Sarai Sarvide, Purificacion Ripalda-Cemborain, Laura Sudupe, Emma Muiños-Lopez, Vincenzo Lagani, Jesper Tegner, Borja Saez-Ochoa, Isabel A Calvo, David Gomez-Cabrero, Felipe Prosper
Journal: Blood
Blood (2023) 142 (Supplement 1): 2706.
https://doi.org/10.1182/blood-2023-179730
Published: 2023
Journal Articles

Spatial Transcriptomics Unveils Novel Potential Mechanisms of Disease in a MI cγ1 Multiple Myeloma in vivo Model

Laura Sudupe, Emma Muiños-Lopez, Isabel A Calvo, Ana Rosa Lopez-Perez, Amaia Vilas-Zornoza, Sarai Sarvide, Purificacion Ripalda-Cemborain, Azari Bantan, Jin Ye, Vincenzo Lagani, Paula Aguirre-Ruiz, Patxi San-Martin, Itziar Cenzano, Marta Larrayoz, Laura Alvarez-Gigli, Marta Abengozar-Muela, Borja Saez-Ochoa, Phillip T Newton, Jesper Tegner, Bruno Paiva, Jose A. A Martinez-Climent, David Gomez-Cabrero, Felipe Prosper
Journal: Blood
Blood (2023) 142 (Supplement 1): 4076.
https://doi.org/10.1182/blood-2023-181643
Published: 2023
Journal Articles

Longitudinal Screening of Mutant Hematopoietic Progenitor Cells (HPC) in Multiple Myeloma (MM) and Its Association with Secondary Primary Malignancies (SPM)

Cristina Perez, Maria Jose Larrayoz, Iria Vazquez, Irache Erdozain, Noemi Puig, María T Cedena, Catarina Maia, Amagoia Mañu, Natalia Gordillo, Oihane Churruca, Diego Alignani, Sarai Sarvide, Albert Oriol Rocafiguera, Laura Rosiñol, Rafael Ríos, Marta Sonia Gonzalez Perez, Ana Pilar Gonzalez-Rodriguez, Felipe De Arriba, Jose Maria Moraleda, Jesus Martin Sanchez, Luis Palomera, Valentin Cabanas Perianes, Maria Jose Calasanz, Joaquin Martinez-Lopez, Maria Victoria Mateos, Joan Bladé, Juan Jose Lahuerta Palacios, Jesus San-Miguel, Bruno Paiva
Journal: Blood
Blood (2023) 142 (Supplement 1): 533.
https://doi.org/10.1182/blood-2023-185737
Published: 2023
Journal Articles

Minimal Residual Disease Detection By Single Cell DNA Sequencing Technology: A Feasible Approach for Clinical Application and Identification of the Landscape of MRD Clones

Ana Alfonso Pierola, Beñat Ariceta, Amaia Vilas-Zornoza, Paula Aguirre-Ruiz, Sarai Sarvide, Patxi San-Martin, Maria-Antonia Fortuño, Catia Simoes, Leire Burgos, Maria Jose Larrayoz, Carmen Chillon, Olga Arce, Teresa Bernal Del Castillo, Mercedes Colorado, Laida Cuevas Palomares, Inmaculada Marchante, Maria Carmen Mateos, Mayte Olave, Jose A. Pérez-Simón, Maria Jose Calasanz, Ramon Garcia-Sanz, Bruno Paiva, Pau Montesinos, Felipe Prosper
Journal: Blood
Blood (2023) 142 (Supplement 1): 2958.
https://doi.org/10.1182/blood-2023-188865
Published: 2023
Journal Articles

Multiomics Profiling of Measurable Residual Disease (MRD) for Understanding the Biology of Ultra-Drug Resistance in Multiple Myeloma (MM)

Camila Guerrero, Noemi Puig, Maria Teresa Cedena Romero, Ibai Goicoechea, Leire Burgos, Diego Alignani, Aitziber Lopez, Sarai Sarvide, María José Calasanz, Ramon Garcia-Sanz, Joaquin Martinez-Lopez, Laura Rosiñol, Esther González Garcia, Albert Oriol, Rafael Rios, Estrella Carrillo-Cruz, Marta Sonia Gonzalez Perez, Carmen Montes Gaisan, Felipe De Arriba, Jose Maria Arguiñano, Josep M Marti, Yolanda Gonzalez-Montes, Antonio Garcia-Guiñon, Juan-José Lahuerta, Joan Bladé Creixenti, Maria-Victoria Mateos, Jesús San-Miguel, Bruno Paiva
Journal: Blood
Blood (2022) 140 (Supplement 1): 246–248.
https://doi.org/10.1182/blood-2022-165402
Published: 2022
Journal Articles

Tumor cells in light-chain amyloidosis and myeloma show distinct transcriptional rewiring of normal plasma cell development

CME Brief Report
Daniel Alameda, Ibai Goicoechea, Marco Vicari, Elena Arriazu, Alice Nevone, Sara Rodriguez, Marta Lasa, Noemi Puig, Maria Teresa Cedena, Diego Alignani, Sonia Garate, David Lara-Astiaso, Amaia Vilas-Zornoza, Sarai Sarvide, Enrique M. Ocio, Ramon Lecumberri, Alfonso Garcia de Coca, Jorge Labrador, Maria-Esther Gonzalez, Luis Palomera, Mercedes Gironella, Valentin Cabañas, Maria Casanova, Albert Oriol, Isabel Krsnik, Albert Perez-Montaña, Javier de la Rubia, Jose-Enrique de la Puerta, Felipe de Arriba, Vito Michele Fazio, Joaquin Martinez-Lopez, Juan-Jose Lahuerta, Maria-Victoria Mateos, Maria-Dolores Odero, Felipe Prosper, Assaf Weiner, Ido Amit, Mario Nuvolone, Jesus F. San Miguel, Bruno Paiva
Journal: Blood
Blood (2021) 138 (17): 1583–1589.
https://doi.org/10.1182/blood.2020009754
Published: 2021
Includes: Supplemental data
Journal Articles

Deep MRD profiling defines outcome and unveils different modes of treatment resistance in standard- and high-risk myeloma

Clinical Trials & Observations
Ibai Goicoechea, Noemi Puig, Maria-Teresa Cedena, Leire Burgos, Lourdes Cordón, María-Belén Vidriales, Juan Flores-Montero, Norma C. Gutierrez, Maria-Jose Calasanz, Maria-Luisa Martin Ramos, David Lara-Astiaso, Amaia Vilas-Zornoza, Diego Alignani, Idoia Rodriguez, Sarai Sarvide, Daniel Alameda, Juan José Garcés, Sara Rodriguez, Vicente Fresquet, Jon Celay, Ramón Garcia-Sanz, Joaquin Martinez-Lopez, Albert Oriol, Rafael Rios, Jesus Martin-Sanchez, Rafael Martinez-Martinez, Josep Sarra, Miguel-Teodoro Hernandez, Javier de la Rubia, Isabel Krsnik, Jose-Maria Moraleda, Luis Palomera, Joan Bargay, Jose-Angel Martinez-Climent, Alberto Orfao, Laura Rosiñol, Maria-Victoria Mateos, Juan-José Lahuerta, Joan Blade, Jesús San Miguel, Bruno Paiva
Journal: Blood
Blood (2021) 137 (1): 49–60.
https://doi.org/10.1182/blood.2020006731
Published: 2021
Includes: Supplemental data
Journal Articles

Immunologic Characterization of Coronavirus Disease 2019 (COVID-19) Patients with Hematological Cancer: Biologic and Clinical Significance

Catarina Maia, Esperanza Martín-Sánchez, Juan José Garcés, Ascensión López-Diaz de Cerio, Susana Inogés, MD PhD, Manuel Landecho, Belen Gil-Alzugaray, Cristina Pérez Ruiz, Cirino Botta, MDPhD, Aintzane Zabaleta, PhD, Felix Alegre, MD, César Rincón, Laura Blanco, Sarai Sarvide, Amaia Vilas-Zornoza, PhD, Diego Alignani, PhD, Cristina Moreno, Monica Olid, Andrés Blanco, Josepmaria Argemi, Bruno Paiva, PhD, Jose-Ramon Yuste
Journal: Blood
Blood (2020) 136 (Supplement 1): 22–23.
https://doi.org/10.1182/blood-2020-136969
Published: 2020
Journal Articles

Immunogenomic identification and characterization of granulocytic myeloid-derived suppressor cells in multiple myeloma

Cristina Perez, Cirino Botta, Aintzane Zabaleta, Noemi Puig, Maria-Teresa Cedena, Ibai Goicoechea, Daniel Alameda, Edurne San José-Eneriz, Juana Merino, Paula Rodríguez-Otero, Catarina Maia, Diego Alignani, Patricia Maiso, Irene Manrique, David Lara-Astiaso, Amaia Vilas-Zornoza, Sarai Sarvide, Caterina Riillo, Marco Rossi, Laura Rosiñol, Albert Oriol, María-Jesús Blanchard, Rafael Rios, Anna Sureda, Jesus Martin, Rafael Martinez, Joan Bargay, Javier de la Rubia, Miguel-Teodoro Hernandez, Joaquin Martinez-Lopez, Alberto Orfao, Xabier Agirre, Felipe Prosper, Maria-Victoria Mateos, Juan-José Lahuerta, Joan Blade, Jesús F. San-Miguel, Bruno Paiva
Journal: Blood
Blood (2020) 136 (2): 199–209.
https://doi.org/10.1182/blood.2019004537
Published: 2020
Includes: Supplemental data
Journal Articles

Biological and clinical significance of dysplastic hematopoiesis in patients with newly diagnosed multiple myeloma

Catarina Maia, Noemi Puig, Maria-Teresa Cedena, Ibai Goicoechea, Rafael Valdes-Mas, Iria Vazquez, Maria-Carmen Chillon, Paula Aguirre, Sarai Sarvide, Francisco Javier Gracia-Aznárez, Gorka Alkorta, Maria-Jose Calasanz, Ramon Garcia-Sanz, Marcos Gonzalez, Norma C. Gutierrez, Joaquin Martinez-Lopez, José J. Perez, Juana Merino, Cristina Moreno, Leire Burgos, Diego Alignani, Cirino Botta, Felipe Prosper, Sergio Matarraz, Alberto Orfao, Albert Oriol, Ana-Isabel Teruel, Raquel de Paz, Felipe de Arriba, Miguel T. Hernandez, Luis Palomera, Rafael Martinez, Laura Rosiñol, Maria-Victoria Mateos, Juan-Jose Lahuerta, Joan Blade, Jesus F. San Miguel, Bruno Paiva
Journal: Blood
Blood (2020) 135 (26): 2375–2387.
https://doi.org/10.1182/blood.2019003382
Published: 2020
Includes: Supplemental data
Journal Articles

Single-Cell Characterization of the Multiple Myeloma (MM) Immune Microenvironment Identifies CD27-Negative T Cells As Potential Source of Tumor-Reactive Lymphocytes

Cirino Botta, MD, Cristina Pérez Ruiz, Ibai Goicoechea, PhD, Noemi Puig, MD PhD, María Teresa Cedena, Lourdes Cordon, Aintzane Zabaleta, PhD, Leire Burgos, Catarina Maia, Sara Rodríguez, PhD, Idoia Rodriguez, Sarai Sarvide, Diego Alignani, PhD, Amaia Vilas-Zornoza, PhD, Erika Lorenzo-Vivas, PhD, Laura Rosinol Dachs, Albert Oriol, MD, María Jesús Blanchard, Rafael Rios, MD PhD, Anna Sureda, MD PhD, Rafael Martínez, Jesús Martín, Joan Bargay, MD PhD, Javier De La Rubia, Marco Rossi, MD, Pierosandro Tagliaferri, MD, Pierfrancesco Tassone, MD, Massimo Gentile, Juana Merino, Felipe Prosper, MD PhD, Alberto Orfao, MD PhD, Maria-Victoria Mateos, Juan-José Lahuerta, MD PhD, Joan Bladé, MD PhD, Jesús San-Miguel, Bruno Paiva, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 506.
https://doi.org/10.1182/blood-2019-123974
Published: 2019
Journal Articles

Detailed Phenotypic, Molecular and Functional Profiling of Myeloid Derived Suppressor Cells (MDSCs) in the Tumor Immune Microenvironment (TIME) of Multiple Myeloma (MM)

Cristina Pérez Ruiz, Aintzane Zabaleta, PhD, Noemi Puig, MD PhD, María Teresa Cedena, Juana Merino, Diego Alignani, PhD, Sonia Garate, Ibai Goicoechea, PhD, David Lara-Astiaso, PhD, Sarai Sarvide, Cirino Botta, MD, Joaquin Martinez Lopez, MD PhD, Albert Oriol, MD, Rafael Rios, MD PhD, Laura Rosinol, MD PhD, Maria-Victoria Mateos, MD PhD, Juan-José Lahuerta, MD PhD, Joan Bladé, MD, Jesus F San-Miguel, MD PhD, Bruno Paiva, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4436.
https://doi.org/10.1182/blood-2018-99-111102
Published: 2018
Journal Articles

Understanding the Cellular Origin and Pathogenic Transcriptional Programs in Multiple Myeloma (MM) and Light-Chain Amyloidosis (AL) through the Dissection of the Normal Plasma Cell (PC) Development

Daniel Alameda, PhD, Marco Vicari, MD, David Lara-Astiaso, PhD, Marta Lasa, Noemi Puig, MD PhD, Maria Teresa Cedena Romero, MD PhD, Idoia Rodriguez, Diego Alignani, PhD, Amaia Vilas-Zornoza, PhD, Ibai Goicoechea, PhD, Sarai Sarvide, Enrique M. Ocio, MD, Ramon Lecumberri, MD PhD, Alfonso García de Coca, MD PhD, Jorge Labrador, MD, Esther González Garcia, MD, Luis Palomera, MD PhD, Mercedes Gironella, MD, Valentin Cabañas, MD, Maria Casanova, MD, Albert Oriol, MD, Isabel Krsnik, MD PhD, Albert Pérez, MD, Joaquin Martinez Lopez, MD PhD, Maria-Victoria Mateos, MD PhD, Juan-José Lahuerta, MD PhD, Felipe Prosper, MD PhD, Assaf Weiner, PhD, Ido Amit, PhD, Jesús F San-Miguel, MD, Bruno Paiva, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 188.
https://doi.org/10.1182/blood-2018-188
Published: 2018
Journal Articles

Clinical Significance and Transcriptional Profiling of Persistent Minimal Residual Disease (MRD) in Multiple Myeloma (MM) Patients with Standard-Risk (SR) and High-Risk (HR) Cytogenetics

Ibai Goicoechea, PhD, Noemi Puig, MD PhD, María Teresa Cedena, Lourdes Cordon, Maria-Belen Vidriales, MD, Leire Burgos, Juan Flores-Montero, Norma C. Gutierrez, MD PhD, Maria Jose Calasanz, BSc, PhD, Maria Luisa Martin-Ramos, David Lara-Astiaso, PhD, Amaia Vilas-Zornoza, PhD, Diego Alignani, PhD, Idoia Rodriguez, Sarai Sarvide, Ramon Garcia-Sanz, MD PhD, Joaquin Martinez-Lopez, MD PhD, Albert Oriol, MD, Rafael Rios, MD PhD, Jesús Martín, Rafael Martínez, Josep Sarra, Miguel T Hernández, MD PhD, Javier De La Rubia, MD, Isabel Krsnik, Jose Maria Moraleda, Luis Palomera, MD PhD, Joan Bargay, MD PhD, Alberto Orfao, MD PhD, Laura Rosiñol, Maria-Victoria Mateos, MD PhD, Juan Jose Lahuerta, MD PhD, Joan Bladé, MD PhD, Jesus F San-Miguel, MD PhD, Bruno Paiva, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 112.
https://doi.org/10.1182/blood-2018-99-113312
Published: 2018
Journal Articles

Pre-Clinical Efficacy of the Anti-CD38 Monoclonal Antibody (mAb) Isatuximab in Acute Myeloid Leukemia (AML)

Tomas Jelinek, Aintzane Zabaleta, PhD, Cristina Perez, Daniel Ajona, PhD, Diego Alignani, PhD, Idoia Rodriguez, Sonia Garate, Sarai Sarvide, Marta Lasa, Patricia Maiso, PhD, Felipe Prosper, MDPhD, Roman Hajek, Jesus F. San Miguel, MD, Bruno Paiva, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2655.
https://doi.org/10.1182/blood.V130.Suppl_1.2655.2655
Published: 2017