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Journal Articles

Identification of Molecular Mechanisms Governing CAR-T Cell Response in MM Patients Using Single Cell Transcriptomics

Lorea Jordana-Urriza, Guillermo Serrano, Maria Erendira Calleja-Cervantes, Patxi San Martin-Uriz, Amaia Vilas-Zornoza, Asier Ullate-Agote, Aintzane Zabaleta, Diego Alignani, Teresa Lozano, Valentin Cabañas, Almudena Navarro-Bailón, Aina Oliver-Caldes, Marta Español-Rego, Mariona Pascal, Manel Juan, Álvaro Urbano-Ispizua, Juan Luis Reguera, Jose Maria Moraleda, Maria-Victoria Mateos, Fermin Sanchez-Guijo, Ana Alfonso Pierola, José J. Rifón Roca, Paula Rodríguez-Otero, Carlos Fernandez de Larrea, Bruno Paiva, Susana Inogés, Ascensión López-Diaz de Cerio, Juan Jose Lasarte, Jesús San-Miguel, Juan Roberto Rodriguez-Madoz, Mikel Hernáez, Felipe Prósper
Journal: Blood
Blood (2022) 140 (Supplement 1): 7366–7368.
https://doi.org/10.1182/blood-2022-163082
Published: 2022
Journal Articles

Characterization of Transcriptional Alterations Leading to Aberrant Myeloid Differentiation in Myelodysplastic Syndromes

Aintzane Diaz-Mazkiaran, Jesús De la Fuente, Guillermo Serrano, Paula Garcia-Olloqui, Nerea Berastegui, Marina Ainciburu, Ana Alfonso Pierola, Amaia Vilas-Zornoza, Patxi San Martin-Uriz, Jose Maria Lamo De Espinosa, Mikel San Julián, Pamela Acha, Francesc Solé, Tamara Jimenez, Félix López Cadenas, Maria Diez-Campelo, Antonieta Molero, Maria Julia Montoro, David Valcarcel, Teresa Ezponda, Mikel Hernáez, Felipe Prosper
Journal: Blood
Blood (2022) 140 (Supplement 1): 5852–5854.
https://doi.org/10.1182/blood-2022-166921
Published: 2022
Journal Articles

BCMA CAR-T Cell Phenotype and Functionality Is Affected By Disease Stage of Multiple Myeloma Patients

Angel Martin-Mallo, Maria Erendira Calleja-Cervantes, Patxi San Martin-Uriz, Amaia Vilas-Zornoza, Aintzane Zabaleta, Diego Alignani, Paula Rodríguez-Márquez, Saray Rodríguez-Diaz, Rebeca Martínez-Turrillas, Patricia Jauregui, Cristina Calviño, Maria Luisa Palacios-Berraquero, Candela Ceballos, Jorge Illarramendi Esteban, Diana Gisell Gabaldon Limas, Maria Cruz Viguria, Ana Margarita Redondo, Manel Juan, Álvaro Urbano-Ispizua, Carlos Fernandez de Larrea, Paula Rodríguez-Otero, Jose J. Rifon Roca, Ana Alfonso Pierola, Teresa Lozano, Juan Jose Lasarte, Bruno Paiva, Susana Inogés, Ascensión López-Diaz de Cerio, Jesús San-Miguel, Juan Roberto Rodriguez-Madoz, Felipe Prósper
Journal: Blood
Blood (2022) 140 (Supplement 1): 12708–12710.
https://doi.org/10.1182/blood-2022-163149
Published: 2022
Journal Articles

Deep Deconvolution of the Hematopoietic Stem Cell Regulatory Microenvironment Reveals a High Degree of Specialization and Conservation between Mouse and Human

Jin Ye, Isabel A Calvo, Itziar Cenzano, Amaia Vilas-Zornoza, Xabier Martinez-de-Morentin, Miren Lasaga, Diego Alignani, Bruno Paiva, Ana C Viñado, Patxi San Martin-Uriz, Juan P Romero, Delia Quilez Agreda, Marta Miñana Barrios, Ignacio Sancho González, Gabriele Todisco, Luca Malcovati, Nuria Planell, Borja Saez, Jesper Tegner, Felipe Prosper, David Gomez Cabrero
Journal: Blood
Blood (2021) 138 (Supplement 1): 2168.
https://doi.org/10.1182/blood-2021-150612
Published: 2021
Journal Articles

Single-Cell Transcriptomics Study of Human Hematopoietic Progenitors Reveals Alterations Associated with Aging and Myeloid Malignancies

Marina Ainciburu, Teresa Ezponda, Nerea Berastegui, Ana Alfonso Pierola, Amaia Vilas-Zornoza, Patxi San Martin-Uriz, Diego Alignani, Jose Maria Lamo De Espinosa, Mikel San Julián, Tamara Jimenez, Felix López Cadenas, Sandra Muntion, Fermin Sanchez-Guijo, Antonieta Molero Yordi, María Julia Montoro, Guillermo Serrano, Aintzane Diaz-Mazkiaran, Miren Lasaga, Gomez-Cabrero David, Maria Diez-Campelo, David Valcarcel, Mikel Hernáez, Juan P. Romero, Felipe Prosper
Journal: Blood
Blood (2021) 138 (Supplement 1): 1082.
https://doi.org/10.1182/blood-2021-153550
Published: 2021
Journal Articles

CAR Density Influences Antitumoral Efficacy of BCMA CAR-T Cells and Correlates with Clinical Outcome

Paula Rodriguez-Marquez, Maria Erendira Calleja-Cervantes, Guillermo Serrano, Maria Luisa Palacios-Berraquero, Diego Alignani, Patxi San Martin-Uriz, Amaia Vilas-Zornoza, Candela Ceballos, Angel Martin-Mallo, Saray Rodríguez-Diaz, Rebeca Martínez-Turrillas, Patricia Jauregui, Cristina Calviño, Susana Inogés, Ascensión López-Diaz de Cerio, Aina Oliver-Caldés, Marta Español-Rego, Mariona Pascal, Beatriz Martin-Antonio, Manel Juan, Álvaro Urbano-Ispizua, Carlos Fernández De Larrea, Maria Cruz Viguria, Ana Margarita Redondo, Paula Rodríguez-Otero, Jose J. Rifon Roca, Ana Alfonso Pierola, Juan Jose Lasarte, Teresa Lozano, Bruno Paiva, Jesús F. San-Miguel, Mikel Hernáez, Juan Roberto Rodriguez-Madoz, Felipe Prósper
Journal: Blood
Blood (2021) 138 (Supplement 1): 735.
https://doi.org/10.1182/blood-2021-148578
Published: 2021
Journal Articles

Transcriptional Regulation of Hematopoietic Stem Cells in Aging and Myelodysplastic Syndrome Reveals DDIT3 As a Potential Driver of Transformation

Teresa Ezponda, Juan P. Romero, Marina Ainciburu, Ana Alfonso, Nerea Berastegui, Amaia Vilas-Zornoza, PhD, Patxi San Martin-Uriz, Laura Castro, Victoria Riego, Tamara Jimenez, Félix López Cadenas, MD, Jesus M Hernández-Sánchez, Antonieta Molero, MD, Julia Montoro, Bárbara Tazón, PhD, Bruno Paiva, PhD, María Díez-Campelo, MD PhD, David Valcarcel, David Lara-Astiaso, Felipe Prosper
Journal: Blood
Blood (2019) 134 (Supplement_1): 3764.
https://doi.org/10.1182/blood-2019-122686
Published: 2019