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Paula Aguirre
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Journal Articles

Comprehensive Characterization of the Bone Marrow Microenvironment Transcriptional Remodeling in the Progression from MGUS to Smoldering and Multiple Myeloma

Itziar Cenzano, Miguel Cocera, Azari Bantan, Marta Larrayoz, Amaia Vilas-Zornoza, Patxi San-Martin, Paula Aguirre-Ruiz, Beñat Ariceta, Jin Ye, Diego Alignani, Aitziber Lopez, Aleksandra Kurowska, Fatimah AlSultan, Raghad Shuwaikan, Vincenzo Lagani, Jesper Tegner, Iñaki I. Martin Subero, Jose A. A Martinez-Climent, Xabier Agirre, Borja Saez-Ochoa, Bruno Paiva, Jesus San-Miguel, Mikel Hernaez, Isabel A Calvo, David Gomez-Cabrero, Felipe Prosper
Journal: Blood
Blood (2023) 142 (Supplement 1): 88.
https://doi.org/10.1182/blood-2023-178534
Published: 2023
Journal Articles

Minimal Residual Disease Detection By Single Cell DNA Sequencing Technology: A Feasible Approach for Clinical Application and Identification of the Landscape of MRD Clones

Ana Alfonso Pierola, Beñat Ariceta, Amaia Vilas-Zornoza, Paula Aguirre-Ruiz, Sarai Sarvide, Patxi San-Martin, Maria-Antonia Fortuño, Catia Simoes, Leire Burgos, Maria Jose Larrayoz, Carmen Chillon, Olga Arce, Teresa Bernal Del Castillo, Mercedes Colorado, Laida Cuevas Palomares, Inmaculada Marchante, Maria Carmen Mateos, Mayte Olave, Jose A. Pérez-Simón, Maria Jose Calasanz, Ramon Garcia-Sanz, Bruno Paiva, Pau Montesinos, Felipe Prosper
Journal: Blood
Blood (2023) 142 (Supplement 1): 2958.
https://doi.org/10.1182/blood-2023-188865
Published: 2023
Journal Articles

Light Chain Amyloidosis Plasma Cells Show Specific Chromatin Accessibility and Transcriptome

Beñat Ariceta, Alice Nevone, Itziar Cenzano, Ane Amundarain, Amaia Vilas-Zornoza, Leire Garate, Paula Aguirre-Ruiz, Estibaliz Miranda, Patxi San-Martin, Paolo Milani, Ramon Lecumberri Villamediana, Diego Alignani, Giovanni Palladini, Bruno Paiva, Jose Ignacio Martin-Subero, Giampaolo Merlini, Jesus San-Miguel, Mikel Hernaez, David Gomez-Cabrero, Xabier Agirre, Mario Nuvolone, Felipe Prosper
Journal: Blood
Blood (2023) 142 (Supplement 1): 4676.
https://doi.org/10.1182/blood-2023-185614
Published: 2023
Journal Articles

A Multi-Omic Study Unveils a Clonal Population of TET2-Mutated Infiltrating T-Cells in Germinal Center B Cell Lymphomas (DLBCL and FL)

Sofia Huerga, Beñat Ariceta, Paula Aguirre-Ruiz, Patxi San-Martin, Sarai Sarvide, Marta Abengozar-Muela, Diego Alignani, Rocio Figueroa, Carlos Grande, Alvaro Lopez-Janeiro, Emma Muiños-Lopez, Juan Roberto Rodriguez-Madoz, Amaia Vilas-Zornoza, Felipe Prosper, Miguel Canales
Journal: Blood
Blood (2023) 142 (Supplement 1): 3003.
https://doi.org/10.1182/blood-2023-182830
Published: 2023
Journal Articles

Combined Single-Cell and Spatial Transcriptomics Unveil the Complex Organization of the Non-Immune Human Bone Marrow Microenvironment during Aging

Itziar Cenzano, Miguel Cocera, Robert Lehmann, Jin Ye, Amaia Vilas-Zornoza, Patxi San-Martin, Paula Aguirre-Ruiz, Diego Alignani, Aitziber Lopez, Bruno Paiva, Marta Miñana Barrios, Ignacio Sancho Gonzalez, Javier Ruiz, Sarai Sarvide, Purificacion Ripalda-Cemborain, Laura Sudupe, Emma Muiños-Lopez, Vincenzo Lagani, Jesper Tegner, Borja Saez-Ochoa, Isabel A Calvo, David Gomez-Cabrero, Felipe Prosper
Journal: Blood
Blood (2023) 142 (Supplement 1): 2706.
https://doi.org/10.1182/blood-2023-179730
Published: 2023
Journal Articles

The Transcriptional Impact of 5q Deletion in MDS at Single Cell Resolution

Aintzane Diaz-Mazkiaran, Guillermo Serrano, Nerea Berastegui, Paula Garcia-Olloqui, Sofia Huerga, Ana Alfonso Pierola, Asier Ullate-Agote, Beñat Ariceta, Marina Ainciburu, Amaia Vilas-Zornoza, Patxi San-Martin, Paula Aguirre-Ruiz, Jose Maria Lamo De Espinosa, Pamela Acha, Oriol Calvete, Tamara Jimenez, Antonieta Molero, Julia Montoro, Maria Diez-Campelo, David Valcarcel, Francesc Sole, Idoia Ochoa, Teresa Ezponda, Felipe Prosper, Mikel Hernaez
Journal: Blood
Blood (2023) 142 (Supplement 1): 1850.
https://doi.org/10.1182/blood-2023-186173
Published: 2023
Journal Articles

Spatial Transcriptomics Unveils Novel Potential Mechanisms of Disease in a MI cγ1 Multiple Myeloma in vivo Model

Laura Sudupe, Emma Muiños-Lopez, Isabel A Calvo, Ana Rosa Lopez-Perez, Amaia Vilas-Zornoza, Sarai Sarvide, Purificacion Ripalda-Cemborain, Azari Bantan, Jin Ye, Vincenzo Lagani, Paula Aguirre-Ruiz, Patxi San-Martin, Itziar Cenzano, Marta Larrayoz, Laura Alvarez-Gigli, Marta Abengozar-Muela, Borja Saez-Ochoa, Phillip T Newton, Jesper Tegner, Bruno Paiva, Jose A. A Martinez-Climent, David Gomez-Cabrero, Felipe Prosper
Journal: Blood
Blood (2023) 142 (Supplement 1): 4076.
https://doi.org/10.1182/blood-2023-181643
Published: 2023
Journal Articles

Biological and clinical significance of dysplastic hematopoiesis in patients with newly diagnosed multiple myeloma

Catarina Maia, Noemi Puig, Maria-Teresa Cedena, Ibai Goicoechea, Rafael Valdes-Mas, Iria Vazquez, Maria-Carmen Chillon, Paula Aguirre, Sarai Sarvide, Francisco Javier Gracia-Aznárez, Gorka Alkorta, Maria-Jose Calasanz, Ramon Garcia-Sanz, Marcos Gonzalez, Norma C. Gutierrez, Joaquin Martinez-Lopez, José J. Perez, Juana Merino, Cristina Moreno, Leire Burgos, Diego Alignani, Cirino Botta, Felipe Prosper, Sergio Matarraz, Alberto Orfao, Albert Oriol, Ana-Isabel Teruel, Raquel de Paz, Felipe de Arriba, Miguel T. Hernandez, Luis Palomera, Rafael Martinez, Laura Rosiñol, Maria-Victoria Mateos, Juan-Jose Lahuerta, Joan Blade, Jesus F. San Miguel, Bruno Paiva
Journal: Blood
Blood (2020) 135 (26): 2375–2387.
https://doi.org/10.1182/blood.2019003382
Published: 2020
Includes: Supplemental data