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Journal Articles

Longitudinal Screening of Mutant Hematopoietic Progenitor Cells (HPC) in Multiple Myeloma (MM) and Its Association with Secondary Primary Malignancies (SPM)

Cristina Perez, Maria Jose Larrayoz, Iria Vazquez, Irache Erdozain, Noemi Puig, María T Cedena, Catarina Maia, Amagoia Mañu, Natalia Gordillo, Oihane Churruca, Diego Alignani, Sarai Sarvide, Albert Oriol Rocafiguera, Laura Rosiñol, Rafael Ríos, Marta Sonia Gonzalez Perez, Ana Pilar Gonzalez-Rodriguez, Felipe De Arriba, Jose Maria Moraleda, Jesus Martin Sanchez, Luis Palomera, Valentin Cabanas Perianes, Maria Jose Calasanz, Joaquin Martinez-Lopez, Maria Victoria Mateos, Joan Bladé, Juan Jose Lahuerta Palacios, Jesus San-Miguel, Bruno Paiva
Journal: Blood
Blood (2023) 142 (Supplement 1): 533.
https://doi.org/10.1182/blood-2023-185737
Published: 2023
Journal Articles

Integrated Multidimensional Flow Cytometry (MFC) and Next-Generation Sequencing (NGS) to Reconstruct Evolutionary Paterns from Dysplasia to Acute Myeloid Leukemia (AML)

Catia Patricia Simoes, Carmen Chillon, David Martínez-Cuadrón, María José Calasanz, María-Belén Vidriales, Iria Vazquez, Montserrat Hernández-Ruano, Beñat Ariceta, Leire Burgos, Diego Alignani, Sarvide Sarai, Sara Villar, Felipe Prósper, Rosa Ayala, Joaquín Martínez-Lopez, Juan Miguel Bergua Burgues, Susana Vives, Jose A. Perez-Simon, María García-Fortes, Marcos González, Jesus San-Miguel, Miguel A. Sanz, Pau Montesinos, Bruno Paiva
Journal: Blood
Blood (2021) 138 (Supplement 1): 520.
https://doi.org/10.1182/blood-2021-145737
Published: 2021
Journal Articles

Nationwide Laboratory Network for AML Cross-Validated NGS Studies: Results from a Real-Life Cohort of the Pethema Group

Claudia Sargas, Rosa Ayala, Carmen Chillon, Maria Jose Larrayoz, Estrella Carrillo, Cristina Bilbao, Manuel Yébenes, Marta Llop, Inmaculada Rapado, Ramon Garcia-Sanz, Iria Vazquez, Elena Soria, Santiago Sánchez-Sosa, Kamila Janusz, Carmen Botella, Josefina Serrano, David Martinez-Cuadron, Juan-Miguel Bergua, Maria Luz Amigo, Pilar Martinez Sanchez, Mar Tormo, Teresa Bernal, Pilar Herrera-Puente, Raimundo García-Boyero, Lorenzo Algarra, Maria Jose Sayas, Lisette Costilla-Barriga, Esther Pérez-Santolalla, Inmaculada Marchante, Esperanza Lavilla-Rubira, Víctor Noriega, Juan Manuel Alonso Dominguez, Miguel A. Sanz, Joaquín Sánchez, María Teresa Gómez-Casares, Jose A. Perez-Simon, María José Calasanz, Marcos González, Joaquín Martínez-López, Eva Barragán, Pau Montesinos
Journal: Blood
Blood (2021) 138 (Supplement 1): 1302.
https://doi.org/10.1182/blood-2021-152353
Published: 2021
Journal Articles

Clinical Validation of a NGS Capture Panel to Identify Mutations, Copy Number Variations and Translocations in Patients with Multiple Myeloma

Isabel Cuenca, MSc, Alejandro Medina, MD, Laura Rosinol, MD PhD, Iria Vazquez, PhD BSc, Ricardo Sanchez, Norma C. Gutierrez, MD PhD, Yanira Ruiz-Heredia, Santiago Barrio, Albert Oriol, MD, Maria Luisa Martin-Ramos, Manuela Fernández-Guijarro, María Jesús Blanchard, Rafael Rios, MD PhD, Anna Sureda Balari, MD PhD, Miguel T Hernández, Javier de la Rubia, Gorka Alkorta, Xabier Agirre, PhD, Gonzalo R Ordóñez, Rafael Valdés-Mas, Maria-Victoria Mateos, MD PhD, Joan Blade Creixenti, Juan Jose Lahuerta, MD PhD, Jesus F. San-Miguel, MD PhD, Maria Jose Calasanz, PhD BSc, Ramon Garcia-Sanz, Joaquin Martinez-Lopez, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 13–14.
https://doi.org/10.1182/blood-2020-140711
Published: 2020
Journal Articles

Biological and clinical significance of dysplastic hematopoiesis in patients with newly diagnosed multiple myeloma

Catarina Maia, Noemi Puig, Maria-Teresa Cedena, Ibai Goicoechea, Rafael Valdes-Mas, Iria Vazquez, Maria-Carmen Chillon, Paula Aguirre, Sarai Sarvide, Francisco Javier Gracia-Aznárez, Gorka Alkorta, Maria-Jose Calasanz, Ramon Garcia-Sanz, Marcos Gonzalez, Norma C. Gutierrez, Joaquin Martinez-Lopez, José J. Perez, Juana Merino, Cristina Moreno, Leire Burgos, Diego Alignani, Cirino Botta, Felipe Prosper, Sergio Matarraz, Alberto Orfao, Albert Oriol, Ana-Isabel Teruel, Raquel de Paz, Felipe de Arriba, Miguel T. Hernandez, Luis Palomera, Rafael Martinez, Laura Rosiñol, Maria-Victoria Mateos, Juan-Jose Lahuerta, Joan Blade, Jesus F. San Miguel, Bruno Paiva
Journal: Blood
Blood (2020) 135 (26): 2375–2387.
https://doi.org/10.1182/blood.2019003382
Published: 2020
Includes: Supplemental data
Journal Articles

Strategy for Identification of an Inherited Leukemia Predisposition in a 299 Patients Cohort with Tumor-Only Sequencing Data

Almudena Aguilera Díaz, MSc, BS, Sara Palomino-Echeverria, MSc, BSc, Iria Vazquez, PhD BSc, Beñat Ariceta, BSc, Maria Jose Larrayoz, BSc, Amagoia Mañu, BSc, Zuriñe Blasco-Iturri, MSc, BSc, Matxalen Olivares Salaverri, MD, Maria Teresa Olave Rubio, MD, Teresa Bernal Del Castillo, MD PhD, Jose J. Rifon Roca, MD, Ana Alfonso Pierola, MD PhD, Felipe Prosper, MD PhD, Marta Fernández-Mercado, PhD MSc, BSc, Maria Jose Calasanz, PhD BSc
Journal: Blood
Blood (2019) 134 (Supplement_1): 1415.
https://doi.org/10.1182/blood-2019-126634
Published: 2019
Journal Articles

The Presence of MDS-like Phenotypic Abnormalities (MDS-PA) Identifies Newly Diagnosed Multiple Myeloma (MM) Patients with MDS/AML-Related Somatic Mutations and Inferior Survival

Bruno Paiva, PhD, Noemi Puig, MD PhD, Maria Teresa Cedena, Iria Vazquez, PhD, Carmen Chillon, Yanira Ruiz, Joaquin Martinez-Lopez, Ramon Garcia-Sanz, Marcos González, MD PhD, Xabier Agirre, PhD, Maria-Jose Calasanz, Leire Burgos, Diego Alignani, Felipe Prosper, MD, Sergio Matarraz, Alberto Orfao, MD PhD, Albert Oriol, MD, Ana Isabel Teruel, MD, M Asuncion Echeveste, Raquel De Paz, PhD, Felipe De Arriba, Miguel-T Hernandez, Gemma Azaceta, MD PhD, Rafael Martinez, MD, Maria-Victoria Mateos, MD PhD, Joan Bladé, Juan José Lahuerta, MD PhD, Jesus San Miguel, MDPhD
Journal: Blood
Blood (2016) 128 (22): 375.
https://doi.org/10.1182/blood.V128.22.375.375
Published: 2016
Journal Articles

Functional Analysis of the GATA2 Promoter Shows That Mutations of GATA2 Impair Its Own Transcriptional Regulation

Xabier Cortes-Lavaud, M.Sc., Miren Maicas, Ph.D., Iria Vazquez, Ph.D., Carmen Vicente, Ph.D., Leire Urquiza, M.Sc., Maria A Garcia-Sanchez, Ph.D., Maria D Odero, MD, Ph.D.
Journal: Blood
Blood (2012) 120 (21): 1233.
https://doi.org/10.1182/blood.V120.21.1233.1233
Published: 2012
Journal Articles

MYB Overexpression Is Directly Involved in Acute Myeloid Leukemia Pathogenesis and Could Constitute a New Therapeutic Target for Patients with Aberrant Expression of This Gene.

Carmen Vicente, Ph.D., Ana Conchillo, Ph.D., Daphnie Pauwels, BSc, Iria Vazquez, Ph.D., Laura Garcia-Orti, BSc, Maria J. Calasanz, Ph.D., Idoya Lahortiga, Ph.D., Jan Cools, Ph.D., Maria D. Odero, MD, Ph.D.
Journal: Blood
Blood (2009) 114 (22): 2402.
https://doi.org/10.1182/blood.V114.22.2402.2402
Published: 2009
Journal Articles

Prevalence of EVI1 Overexpression and Its Impact on Diagnosis and Prognosis in Acute Myeloid Leukemia: A Study of 490 Patients from the Spanish Group of Myeloid Malignancies of the RTICC.

Iria Vazquez, BSc, José Cervera, MD, PhD, Maria Gomez-Benito, Ph.D., Nerea Marcotegui, BSc, Miren Maicas, BSc, Ana Conchillo, Ph.D., Ana Valencia, Ph.D., Eva Lumbreras, Ph.D., Salut Brunet, MD, Maria T. Gómez-Casares, MD, Ph.D., Jesus-Maria Hernandez-Rivas, MD, Ph.D., Maria J. Calasanz, PhD, Jorge Sierra, MD, PhD, Maria D. Odero, MD, PhD
Journal: Blood
Blood (2008) 112 (11): 1515.
https://doi.org/10.1182/blood.V112.11.1515.1515
Published: 2008
Journal Articles

A Gain of Function Mutation in JAK2 Is Frequently Found in Patients with AML-M2 and Normal Karyotype.

Nerea Marcotegui, BSc, Idoya Lahortiga, PhD, Iria Vazquez, BSc, Jose L. Vizmanos, PhD, Ion Cristobal, BSc, Cristina Ormazabal, BSc, Eva Bandres, PhD, Maria J. Larrayoz, BSc, Carmen Vicente, BSc, Maria J. Calasanz, PhD, María D. Odero, MD, PhD
Journal: Blood
Blood (2005) 106 (11): 2366.
https://doi.org/10.1182/blood.V106.11.2366.2366
Published: 2005
Journal Articles

GATA2 Is Overexpressed in 46% of Patients with AML and Normal Karyotype. The Mutational Pattern FLT3-ITD/GATA2/WT1 Could Define a Group of Patients with Normal Karyotype and AML-M1 Subtype.

Idoya Lahortiga, PhD, Iria Vazquez, BSc, Nerea Marcotegui, BSc, Eva Bandres, PhD, Raquel Malumbres, PhD, Maria J. Larrayoz, BSc, Carmen Vicente, BSc, Jose Cervera, MD, PhD, Jesus M. Hernandez, MD, PhD, Jesus Garcia-Foncillas, MD, PhD, Maria T. Ardanaz, MD, Filomena Floristan, MD, Maria J. Calasanz, PhD, Maria D. Odero, MD, PhD
Journal: Blood
Blood (2005) 106 (11): 2378.
https://doi.org/10.1182/blood.V106.11.2378.2378
Published: 2005
Journal Articles

GATA2 May Contribute with EVI1 to the Leukemogenic Mechanism in Patients with 3q21q26 Rearrangements.

Iria Vazquez, BSc, Idoya Lahortiga, PhD, Nerea Marcotegui, BSc, Maria Jose Larrayoz, BSc, Carmen Vicente, BSc, Jesus Maria Hernandez, MD, Jose Cervera, MD, Maria Jesus Vidal, MD, Jose A. Marquez, MD, Maria Jose Calasanz, PhD, Maria Dolores Odero, MD, PhD
Journal: Blood
Blood (2005) 106 (11): 2852.
https://doi.org/10.1182/blood.V106.11.2852.2852
Published: 2005