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Yanira Ruiz-Heredia
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Journal Articles

Adoptively Infused Memory-like Natural Killer Cells Impact Adaptive Immune Responses in Patients with Acute Myeloid Leukemia

Sergio Rutella, Jayakumar Vadakekolathu, Amanda F Cashen, Nitin Mahajan, Yanira Ruiz-Heredia, Alejandro Martín-Muñoz, Santiago Barrio, Melissa M Berrien-Elliott, Jan Davidson-Moncada, Todd A Fehniger
Journal: Blood
Blood (2023) 142 (Supplement 1): 4813.
https://doi.org/10.1182/blood-2023-184986
Published: 2023
Journal Articles

Intracytoplasmatic BCMA Point Mutation and Teclistamab Resistance: Genomic Assessment of a Multidrug-Resistant Multiple Myeloma Patient

Natalia Buenache Cuenda, Hipolito Nicolas Cuesta Hernández, Alicia Giménez Sánchez, Laura Carneros Blanco, Juan Manuel Rosa-Rosa, Yanira Ruiz-Heredia, Enrique Revilla, Seungbin Han, Umair Munawar, Inmaculada Rapado, Rosa Ayala, K. Martin Kortüm, Antonio Valeri, Santiago Barrio, Joaquin Martinez Lopez, Larissa Haertle
Journal: Blood
Blood (2023) 142 (Supplement 1): 1925.
https://doi.org/10.1182/blood-2023-184824
Published: 2023
Journal Articles

Parallel Monitoring of Measurable Residual Disease and Chimerism By NGS in Myelodysplastic Syndrome after Allogenic STEM Cell Transplant

Irene Zamanillo, Santiago Barrio, Alejandro Martín-Muñoz, Sara Dorado, Ana K Ballesteros, Yanira Ruiz-Heredia, Margarita Rodriguez, Carolina Martinez-Laperche, Sandra Martín, Blanca Ferrer Lores, Ivan Martin Castillo, Inmaculada Rapado, Rosa Ayala, Joaquin Martinez-Lopez, Maria Teresa Cedena Romero
Journal: Blood
Blood (2023) 142 (Supplement 1): 6781.
https://doi.org/10.1182/blood-2023-188600
Published: 2023
Journal Articles

Dynamic Response Assesment Combining Liquid Biopsy MRD and PET/CT in Follicular Lymphoma Patients Including CAR-T Cell Therapy

Alejandro Martín-Muñoz, María Poza, Gloria Figaredo, Sara Dorado, Yanira Ruiz-Heredia, Margarita Rodriguez, Laura Rufian, Antonia Rodriguez Izquierdo, Laura Parrilla-Navamuel, Chongwu Wang, Paula Toledo, Carlos Grande Garcia, Tycho Baumann, Maria Calbacho, Inmaculada Rapado, Miguel Gallardo, Miguel Canales, Pilar Sarandeses, Manuela Mollejo, Luis Felipe Casado Montero, Rosa Ayala, Joaquín Martínez-López, Santiago Barrio, Ana Jimenez-Ubieto
Journal: Blood
Blood (2022) 140 (Supplement 1): 3514–3515.
https://doi.org/10.1182/blood-2022-166372
Published: 2022
Journal Articles

Cereblon enhancer methylation and IMiD resistance in multiple myeloma

Clinical Trials & Observations Brief Report
Larissa Haertle, Santiago Barrio, Umair Munawar, Seungbin Han, Xiang Zhou, Cornelia Vogt, Rafael Alonso Fernández, Max Bittrich, Yanira Ruiz-Heredia, Matteo Da Viá, Josip Zovko, Andoni Garitano-Trojaola, Niccolò Bolli, Anna Ruckdeschel, Thorsten Stühmer, Manik Chatterjee, Miriam Kull, Jan Krönke, Xabier Agirre, Jose I. Martin-Subero, Peter Raab, Hermann Einsele, Leo Rasche, Joaquin Martinez-Lopez, Thomas Haaf, K. Martin Kortüm
Journal: Blood
Blood (2021) 138 (18): 1721–1726.
https://doi.org/10.1182/blood.2020010452
Published: 2021
Includes: Supplemental data
Journal Articles

Clinical Validation of a NGS Capture Panel to Identify Mutations, Copy Number Variations and Translocations in Patients with Multiple Myeloma

Isabel Cuenca, MSc, Alejandro Medina, MD, Laura Rosinol, MD PhD, Iria Vazquez, PhD BSc, Ricardo Sanchez, Norma C. Gutierrez, MD PhD, Yanira Ruiz-Heredia, Santiago Barrio, Albert Oriol, MD, Maria Luisa Martin-Ramos, Manuela Fernández-Guijarro, María Jesús Blanchard, Rafael Rios, MD PhD, Anna Sureda Balari, MD PhD, Miguel T Hernández, Javier de la Rubia, Gorka Alkorta, Xabier Agirre, PhD, Gonzalo R Ordóñez, Rafael Valdés-Mas, Maria-Victoria Mateos, MD PhD, Joan Blade Creixenti, Juan Jose Lahuerta, MD PhD, Jesus F. San-Miguel, MD PhD, Maria Jose Calasanz, PhD BSc, Ramon Garcia-Sanz, Joaquin Martinez-Lopez, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 13–14.
https://doi.org/10.1182/blood-2020-140711
Published: 2020
Journal Articles

Validation of the High-Risk Prognostic Score Defined By the Presence of Mutations in NRAS or TP53 in a Cohort of 497 Patients with Acute Myeloid Leukemia

Rosa Ayala, MD PhD, Pau Montesinos, MD PhD, Eva Barragán, PhD, Joaquin Martinez-Lopez, MD, Miguel A. Sanz, Yanira Ruiz-Heredia, Santiago Barrio, Juan Manuel de la Rosa, Inmaculada Rapado, Pilar Martinez, MD, Rafael Colmenares, Maria Pozas, Xabier Gutierrez, María Luz Morales, Noemí Álvarez Sánchez-Redondo
Journal: Blood
Blood (2020) 136 (Supplement 1): 4–5.
https://doi.org/10.1182/blood-2020-137467
Published: 2020
Journal Articles

Making Clinical Decisions to Change Therapy Using Measurable Residual Disease Improves the Outcome in Multiple Myeloma

Joaquin Martinez Lopez, Rafael Alonso Fernández, Sandy W. Wong, MD, Rafael Rios, MD PhD, Nina Shah, MD, Maria Teresa Cedena Romero, MD PhD, Yanira Ruiz-Heredia, Jose M. Sanchez, MD, Santiago Barrio Garcia, PhD, Thomas Martin, III, MD, Jeffrey L. Wolf, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 42–43.
https://doi.org/10.1182/blood-2020-140352
Published: 2020
Journal Articles

Increase of Mitochondrial Activity Contributes to the Bortezomib-Relapsed in Multiple Myeloma, a Novel Therapeutic Opportunity

Alejandra Ortiz-Ruiz, BSc, Yanira Ruiz-Heredia, Mehmet Samur, PhD, Pedro Aguilar-Garrido, Maria Luz Morales, Antonio Valeri, PhD, Almudena Garcia-Ortiz, PhD, Santiago Barrio, PhD, Carmen Bárcena, Rosa Maria Garcia-Martin, Vanesa Garrido, Mariateresa Fulciniti, PhD, Nikhil C. Munshi, MD, María Teresa Cedena, Joaquin Martinez-Lopez, MD PhD, Maria Linares, PhD, Miguel Gallardo, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4408.
https://doi.org/10.1182/blood-2019-123950
Published: 2019
Journal Articles

Focusing PI and IMiD Resistance in Multiple Myeloma: Impact of DNA Methylation

Larissa Haertle, PhD, Max Bittrich, MD, Ramya Potabattula, PhD, Matteo Claudio Da Via', MD, Umair Munawar, MS, BS, Yanira Ruiz-Heredia, Cornelia Vogt, Torsten Steinbrunn, Andoni Garitano-Trojaola, PhD, Thorsten Stuehmer, Joaquin Martinez Lopez, MD PhD, Hermann Einsele, MD, Thomas Haaf, MD PhD, K. Martin Kortüm, MD, Santiago Barrio Garcia, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 404.
https://doi.org/10.1182/blood-2018-99-118944
Published: 2018
Journal Articles

Role of MAX As a Tumor Suppressor Driver Gene in Multiple Myeloma

Santiago Barrio Garcia, PhD, Yanira Ruiz-Heredia, Matteo Da Via', MD, Miguel Gallardo, PhD, Andoni Garitano-Trojaola, PhD, Josip Zovko, MD, Marc S Raab, MD PhD, Pieter Sonneveld, MDPhD, Esteban Braggio, PhD, A. Keith Stewart, MBChB, MBA, Hermann Einsele, Joaquín Martínez, K. Martin Kortüm, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4347.
https://doi.org/10.1182/blood.V130.Suppl_1.4347.4347
Published: 2017
Journal Articles

5q+ MDS Patients with Low RPS14 Expression Are Candidates to Immune-Modulating Drugs

María Linares, PhD, Inmaculada Rapado, Yanira Ruiz-Heredia, Maria Teresa Cedena, Keina Quiroz, Santiago Barrio, PhD, Rosa Ayala, Joaquín Martínez
Journal: Blood
Blood (2017) 130 (Supplement 1): 5303.
https://doi.org/10.1182/blood.V130.Suppl_1.5303.5303
Published: 2017
Journal Articles

Abnormalities in Mitochondrial DNA Copy Number Have Pathogenetic and Prognostic Implications in Multiple Myeloma

Yanira Ruiz-Heredia, Mehmet Kemal Samur, PhD, Alejandra Ortiz-Ruiz, Rafael Alonso Fernández, Beatriz Sanchez-Vega, Alberto Blazquez, Aitor Delmiro, Jose Carlos Martinez-Avila, Esther Onecha, Antonio Valeri, PhD, Miguel Angel Martin, Niccolo Bolli, MD, Yu-Tzu Tai, PhD, Francesco Maura, Raphael Szalat, MD, Mariateresa Fulciniti, PhD, María Linares, PhD, Miguel Gallardo, PhD, Peter J Campbell, MD PhD, Hervé Avet-Loiseau, Juan Jose Lahuerta, Nikhil Munshi, MD, Joaquin Martinez-Lopez, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4378.
https://doi.org/10.1182/blood.V130.Suppl_1.4378.4378
Published: 2017
Journal Articles

IKZF1/3 and CRL4 CRBN E3 Ubiquitin Ligase Mutations Associate with IMiD Resistance in Relapsed Multiple Myeloma

Santiago Barrio Garcia, PhD, Matteo Da Via', MD, Andoni Garitano-Trojaola, PhD, Yanira Ruiz-Heredia, Max Bittrich, MD, ChangXin Shi, PhD, Yuan Zhu, Nicola Lehners, MD, Elias K Mai, MD, Marc S Raab, MD PhD, Pieter Sonneveld, MDPhD, Joaquín Martínez, Andreas Rosenwald, Esteban Braggio, PhD, Hermann Einsele, A. Keith Stewart, MBChB, MBA, K. Martin Kortüm, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 270.
https://doi.org/10.1182/blood.V130.Suppl_1.270.270
Published: 2017
Journal Articles

Targeted RNA-Seq Identify a Subset of Adolescent and Adult Patients with Acute Lymphoblastic Leukemia with BCR-ABL1-like Characteristics

Ricardo Sanchez, Mireia Morgades, M.Prob.S, Rosa Ayala, Esther Onecha, Yanira Ruiz-Heredia, Jose M. Sanchez, Susana Vives, MD, Santiago Mercadal, MD, Ramón Guardia, Marta Cervera, MD, Olga García, Jordi Ribera, Josep-Maria Ribera, MD, Joaquín Martínez
Journal: Blood
Blood (2017) 130 (Supplement 1): 2710.
https://doi.org/10.1182/blood.V130.Suppl_1.2710.2710
Published: 2017
Journal Articles

Ultra-Deep Targeted Sequencing Does Not Identify MM Patients with Different Prognosis: Results from a Randomized Phase II Clinical Trial

Yanira Ruiz-Heredia, Joaquín Martínez-López, MD PhD, Jose Carlos Martínez-Ávila, Beatriz Sanchez-Vega, PhD, Inmaculada Rapado, PhD, Cristina Jimenez, BSc, Esteban Braggio, PhD, Rafael Martinez, MD PhD, Laura Rosiñol, Enrique M. Ocio, MD PhD, M Asuncion Echeveste, Jaime Perez de Oteyza, Albert Oriol, Joan Bargay, MD, Mercedes Gironella, Jesus Martin, Rosa M. Ayala, MD PhD, Joan Bladé, Keith Stewart, M.B., Ch.B., Maria-Victoria Mateos, MD PhD, Jesus San Miguel, MD PhD, Ramon Garcia-Sanz, Juan José Lahuerta, MD PhD, Xabier Aguirre
Journal: Blood
Blood (2016) 128 (22): 2078.
https://doi.org/10.1182/blood.V128.22.2078.2078
Published: 2016
Journal Articles

Prognostic Impact of Molecular Response Assessed By Next-Generation Sequencing in a Large Cohort of Multiple Myeloma Patients

Beatriz Sanchez-Vega, PhD, Rafael Alonso, MD, Isabel Cuenca, Santiago Barrio, PhD, Yanira Ruiz-Heredia, Carlos Marin, Inmaculada Rapado, PhD, Cristina Jimenez, BSc, Xabier Aguirre, Rosa M. Ayala, MD PhD, Teresa Cedena, Bruno Paiva, PhD, Maria-Victoria Mateos, MD PhD, Laura Rosiñol, Joan Bladé, Jesus San Miguel, MD PhD, Ramon Garcia-Sanz, MD PhD, Juan José Lahuerta, MDPhD, Joaquín Martínez-López, MD PhD
Journal: Blood
Blood (2016) 128 (22): 3283.
https://doi.org/10.1182/blood.V128.22.3283.3283
Published: 2016
Journal Articles

Targeted Genomic Mutation Panel (M 3 P) Results from 504 Multiple Myeloma (MM) Patients

K Martin Kortuem, Esteban Braggio, Pieter Sonneveld, MD PhD, Laura Ann Bruins, Santiago Barrio, Davine Hofste op Bruinink, Mark vanDuin, Elias Karl Mai, MD, Nur Hanafiah, Hartmut Goldschmidt, MD, Sanchin Pathangey, Yanira Ruiz Heredia, Inmaculada Rapado, Beatriz Sanchez-Vega, Stefan Knop, Leo Rasche, Christian Langer, Miriam Kull, Lars Bullinger, Monika Engelhardt, Joaquin Martinez-Lopez, Hermann Einsele, Marc S. Raab, A. Keith Stewart
Journal: Blood
Blood (2015) 126 (23): 1795.
https://doi.org/10.1182/blood.V126.23.1795.1795
Published: 2015