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Thorsten Stuehmer
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Journal Articles

Immune Checkpoint CD200/CD200R Decreases T Cell-Mediated Cytotoxicity Via Dok2 and Is Regulated By P53 in Multiple Myeloma

Pooja Shah, Thorsten Stuehmer, Larissa Haertle, Daniela Bruennert, Umair Munawar, Ellen Leich, Sabrina Kraus, Michael Hudecek, Manik Chatterjee, Andreas Schlosser, Martin Kortuem, Ralf C Bargou, Hermann Einsele, Friederike Berberich-Siebelt, Torsten Steinbrunn
Journal: Blood
Blood (2022) 140 (Supplement 1): 7076–7077.
https://doi.org/10.1182/blood-2022-166283
Published: 2022
Journal Articles

Super-Enhancer-Driven PIM Kinase Upregulation in Multiple Myeloma Maintains the Plasma Cell-Specific Oncogenic and Microenvironmental Circuits, and Can be Efficiently Targeted By the Pan-PIM Inhibitor MEN1703

Filip Garbicz, Sonia Debek, Anna Szumera-Ciećkiewicz, Joanna Barankiewicz, Dorota Komar, Michał Pawlak, Aleksandra Matrejek, Thorsten Stuehmer, Aleksander Salomon-Perzynski, Agata Malenda, Julia Ostrowska, Julia Dudkiewicz, Krzysztof Brzózka, Tomasz Rzymski, Daniela Bellarosa, Ewa Lech-Marańda, Monika Prochorec-Sobieszek, Zofia Pilch, Dominika Nowis, Jakub Golab, Helen Tanton, Teru Hideshima, David M. Dorfman, Irena Misiewicz-Krzeminska, Tomasz Sewastianik, Ruben D. Carrasco, Maciej Szydlowski, Przemyslaw Juszczynski
Journal: Blood
Blood (2022) 140 (Supplement 1): 4189–4190.
https://doi.org/10.1182/blood-2022-168770
Published: 2022
Journal Articles

CD200 Expression on Multiple Myeloma Cells Induces Attenuation of T Cell-Mediated Cytotoxicity Via DOK2

Pooja Shah, Thorsten Stuehmer, Daniela Bruennert, Umair Munawar, Ellen Leich, Sabrina Kraus, Michael Hudecek, Manik Chatterjee, Andreas Schlosser, Ralf C Bargou, Hermann Einsele, Friederike Berberich-Siebelt, Torsten Steinbrunn
Journal: Blood
Blood (2021) 138 (Supplement 1): 1587.
https://doi.org/10.1182/blood-2021-153741
Published: 2021
Journal Articles

PIM Kinase Inhibition Decreases the Proangiogenic Properties of Multiple Myeloma Cells and Affects the Metabolic State of the Vascular Endothelium

Filip Garbicz, MD, Anna Szumera-Ciećkiewicz, MD PhD, Joanna Barankiewicz, MD, Dorota Komar, PhD, Michał Pawlak, PhD, Sonia Dębek, MSc, Aleksandra Matrejek, MSc, Thorsten Stuehmer, PhD, Aleksander Salomon-Perzynski, MD, Agata Malenda, MD PhD, Krzysztof Brzózka, PhD, Tomasz Rzymski, PhD, Andrea Massimiliano Tomirotti, PhD, Ewa Lech-Marańda, MD PhD, Monika Prochorec-Sobieszek, MD PhD, Maciej Szydlowski, PhD, Przemyslaw Juszczynski, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 16–17.
https://doi.org/10.1182/blood-2020-134979
Published: 2020
Journal Articles

Clonal Competition Models to Understand Progression and Resistance in Myeloma

Santiago Barrio, PhD, Larissa Haertle, PhD, Umair Munawar, MSc, Lucia Martin, Isabel Cuenca, MSc, Cornelia Vogt, MSc, Andoni Garitano-Trojaola, PhD, Matteo Claudio Da Via', MD, Miguel Gallardo, PhD, Thorsten Stuehmer, PhD, Hermann Einsele, MD, Leo Rasche, MD, Joaquin Martinez-Lopez, MD PhD, Martin Kortüm, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1807.
https://doi.org/10.1182/blood-2019-130812
Published: 2019
Journal Articles

Mechanisms of Proteasome Inhibitor Resistance Selected By Clonal Evolution in Multiple Myeloma

Larissa Haertle, PhD, Santiago Barrio, PhD, Michal Simicek, PhD, Umair Munawar, MSc, Ricardo Sanchez, PhD MD, Max Bittrich, MD, Matteo DaVia, MD, Cornelia Vogt, MSc, Nicola Giesen, MD, Andoni Garitano-Trojaola, PhD, Silvia Nerreter, Thorsten Stuehmer, PhD, Marc S. Raab, MD, Joaquin Martinez Lopez, MD PhD, Roman Hajek, MD, Hermann Einsele, MD, Leo Rasche, MD, Thomas Haaf, MD, Martin Kortüm, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4349.
https://doi.org/10.1182/blood-2019-130847
Published: 2019
Journal Articles

Focusing PI and IMiD Resistance in Multiple Myeloma: Impact of DNA Methylation

Larissa Haertle, PhD, Max Bittrich, MD, Ramya Potabattula, PhD, Matteo Claudio Da Via', MD, Umair Munawar, MS, BS, Yanira Ruiz-Heredia, Cornelia Vogt, Torsten Steinbrunn, Andoni Garitano-Trojaola, PhD, Thorsten Stuehmer, Joaquin Martinez Lopez, MD PhD, Hermann Einsele, MD, Thomas Haaf, MD PhD, K. Martin Kortüm, MD, Santiago Barrio Garcia, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 404.
https://doi.org/10.1182/blood-2018-99-118944
Published: 2018
Journal Articles

The HACE1-NRF2 Axis a Novel Target in Acute Myeloid Leukemia

Andoni Garitano-Trojaola, PhD, Eva Teufel, Nadine Rodhes, Jennifer Kreckel, Thorsten Stuehmer, Matteo Claudio Da Via', MD, Santiago Barrio Garcia, PhD, Torsten Haferlach, MD, Raoul Tibes, Harald Wajant, Andreas Rosenwald, Hermann Einsele, MD, K. Martin Kortüm, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 5132.
https://doi.org/10.1182/blood-2018-99-118270
Published: 2018
Journal Articles

The Role of NRAS G12D Mutations in the Response to Conventional Chemotherapy and 5-Azacitidine in Secondary AML

Andoni Garitano-Trojaola, PhD, Eva Teufel, Matteo Claudio Da Via', MD, Ana Sancho, Nadine Rodhes, Thorsten Stuehmer, Santiago Barrio Garcia, PhD, Jürgen Groll, Torsten Haferlach, MD, Raoul Tibes, Andreas Rosenwald, Hermann Einsele, MD, Martin Kortüm, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 5148.
https://doi.org/10.1182/blood-2018-99-118484
Published: 2018
Journal Articles

Molecular Resistance Mechanisms in Multiple Myeloma

Santiago Barrio Garcia, PhD, Umair Munawar, MS, BS, Thorsten Stuehmer, Hermann Einsele, MD, K. Martin Kortüm, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 471.
https://doi.org/10.1182/blood-2018-99-118700
Published: 2018
Journal Articles

Implications of TP53 alterations for Therapy Response in Multiple Myeloma

Umair Munawar, MS, BS, Santiago Barrio, PhD, Markus Roth, Hermann Einsele, MD, Ralf C Bargou, Thorsten Stuehmer, Martin Kortum, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3189.
https://doi.org/10.1182/blood-2018-99-118658
Published: 2018
Journal Articles

Activated Ral and Mutated RAS Are Independent Drivers of Multiple Myeloma Cell Survival.

Marcel Seibold, Thorsten Stuehmer, Anja Mottok, Claus J Scholz, Manik Chatterjee, Ellen Leich, Martin Kortüm, Andreas Schlosser, Hermann Einsele, Andreas Rosenwald, Ralf C Bargou, Torsten Steinbrunn
Journal: Blood
Blood (2018) 132 (Supplement 1): 3217.
https://doi.org/10.1182/blood-2018-99-119804
Published: 2018
Journal Articles

RAL Mediates Multiple Myeloma Cell Survival Independently of Oncogenic RAS

Marcel Seibold, Thorsten Stuehmer, Nadine Kremer, Anja Mottok, MD PhD, Claus J Scholz, Daniela Bruennert, Manik Chatterjee, Ellen Leich, Andreas Schlosser, Andreas Rosenwald, Hermann Einsele, Ralf C Bargou, Torsten Steinbrunn
Journal: Blood
Blood (2017) 130 (Supplement 1): 4406.
https://doi.org/10.1182/blood.V130.Suppl_1.4406.4406
Published: 2017
Journal Articles

Combined Disruption of Both the MEK/ERK and the IL-6R/STAT3 Pathways Is Required To Induce Apoptosis of Multiple Myeloma Cells in the Presence of Bone Marrow Stromal Cells.

Manik Chatterjee, Thorsten Stuehmer, Pia Herrmann, Kurt Bommert, Bernd Dorken, Ralf C. Bargou
Journal: Blood
Blood (2004) 104 (11): 4839.
https://doi.org/10.1182/blood.V104.11.4839.4839
Published: 2004