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Amanda F Cashen
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Journal Articles

Itacitinib for Prevention of Graft-Versus-Host Disease and Cytokine Release Syndrome in Haploidentical Transplantation

Clinical Trials & Observations
Ramzi Abboud, Mark A. Schroeder, Michael P Rettig, Reyka G Jayasinghe, Feng Gao, Jeremy Eisele, Leah Gehrs, Julie K. Ritchey, Jaebok Choi, Camille N Abboud, Iskra Pusic, Meagan A Jacoby, Peter Westervelt, Matthew Christopher, Amanda F. Cashen, Armin Ghobadi, Keith Stockerl-Goldstein, Geoffrey L Uy, John F. DiPersio
Journal: Blood
Blood blood.2024026497.
https://doi.org/10.1182/blood.2024026497
Published: 2024
Includes: Supplemental data
Journal Articles

Duvelisib for Cytokine Release Syndrome Prophylaxis during CD19-Targeted CAR T Cell Therapy

Michael Slade, Michael P. Rettig, Zachary David Crees, Neha Mehta-Shah, Todd A Fehniger, Amanda F Cashen, Iskra Pusic, Geoffrey L Uy, Peter Westervelt, John DiPersio, Armin Ghobadi
Journal: Blood
Blood (2023) 142 (Supplement 1): 3470.
https://doi.org/10.1182/blood-2023-172439
Published: 2023
Journal Articles

Assessment of T-Cell Receptor (TCR) Mediated T-Cell Activation in Acute Myeloid Leukemia at Diagnosis Has Implications for Risk Stratification and Response to Immune Checkpoint Inhibitors

Nancy BJ Arthur, Agata Gruszczynska, Ma Xenia G Illagan, Michael Prinsen, Sharon E Heath, Tasha Burton, Victoria Donaldson, Cara Lunn Shirai, Eric J. Duncavage, Amanda F Cashen, Geoffrey L Uy, David H Spencer, Stephen M Sykes, Timothy J Ley, Francesca Ferraro
Journal: Blood
Blood (2023) 142 (Supplement 1): 2928.
https://doi.org/10.1182/blood-2023-189573
Published: 2023
Journal Articles

The Relapse-to-Therapy Interval in Relapsed or Refractory Diffuse Large B Cell Lymphoma Is Associated with Clinical Outcomes

Paolo F. Caimi, Christine Auberle, Krishna Goparaju, Molly Megan Gallogly, Firas Baidoun, Amanda F Cashen, Brian T. Hill
Journal: Blood
Blood (2023) 142 (Supplement 1): 1766.
https://doi.org/10.1182/blood-2023-181274
Published: 2023
Journal Articles

Itacitinib for Prevention of Graft-Versus-Host Disease and Cytokine Release Syndrome with T-Cell Replete Peripheral Blood Haploidentical Transplantation

Ramzi Abboud, Mark A. Schroeder, Michael P. Rettig, Feng Gao, Julie K. Ritchey, Camille N. Abboud, Iskra Pusic, Peter Westervelt, Amanda F Cashen, Matt Christopher, Armin Ghobadi, Ramzi Abboud, Keith Stockerl-Goldstein, Geoffrey L Uy, John F. DiPersio, Leah Gehrs
Journal: Blood
Blood (2023) 142 (Supplement 1): 651.
https://doi.org/10.1182/blood-2023-180289
Published: 2023
Journal Articles

Phase II Trial of Duvelisib Maintenance after Autologous Stem Cell Transplant in T-Cell and B-Cell Non-Hodgkin Lymphomas: Results of Safety Lead in

Raya Saba, Neha Mehta-Shah, Armin Ghobadi, John F. DiPersio, Amanda F Cashen, Ningying Wu
Journal: Blood
Blood (2023) 142 (Supplement 1): 6245.
https://doi.org/10.1182/blood-2023-174109
Published: 2023
Journal Articles

Mechanisms of Cytokine-Induced NK Cell Therapy: IL-12/15/18 Induce a Unique Transcriptional, Epigenetic, and Functional Human NK Cell Memory Program

Jennifer Tran, Jennifer Ann Foltz, Pamela Wong, Changxu Fan, Michelle Becker-Hapak, Nancy D Marin, Celia C Cubitt, David A Russler-Germain, Mark Foster, Timothy Schappe, Lynne Marsala, Joseph Rueve, Kimberly Hwang, Ting Wang, Melissa M Berrien-Elliott, Amanda F Cashen, Jeffrey J. Bednarski, Obi Griffith, Malachi Griffith, Allegra Petti, Todd A Fehniger
Journal: Blood
Blood (2023) 142 (Supplement 1): 2067.
https://doi.org/10.1182/blood-2023-182435
Published: 2023
Journal Articles

Predictors of Cytokine Release Syndrome and Neurotoxicity in Patients with Large B-Cell Lymphoma and Their Impact on Survival

Roni Shouval, Christopher Strouse, Soyoung Kim, Temitope Oloyede, Sairah Ahmed, Farrukh T. Awan, Veronika Bachanova, Talha Badar, Pere Barba, Amer M. Beitinjaneh, Amanda F Cashen, Bhagirathbhai Dholaria, Mahmoud Elsawy, Siddhartha Ganguly, Praveen Ramakrishnan Geethakumari, Uri Greenbaum, Hamza Hashmi, Laquisa C. Hill, Michael D. Jain, Tania Jain, Partow Kebriaei, Adam S Kittai, Frederick L. Locke, Premal D. Lulla, Elena Mead, Joseph P McGuirk, Alberto Mussetti, Taiga Nishihori, Amanda L. Olson, Martina Pennisi, Miguel-Angel Perales, Peter A. Riedell, Wael Saber, Sayeef Mirza, Margarida Magalhaes-Silverman, Elizabeth J. Shpall, Mohamed Sorror, Kitsada Wudhikarn, Cameron J. Turtle, Marcelo Pasquini, Amy Moskop
Journal: Blood
Blood (2023) 142 (Supplement 1): 355.
https://doi.org/10.1182/blood-2023-181181
Published: 2023
Journal Articles

Adoptively Infused Memory-like Natural Killer Cells Impact Adaptive Immune Responses in Patients with Acute Myeloid Leukemia

Sergio Rutella, Jayakumar Vadakekolathu, Amanda F Cashen, Nitin Mahajan, Yanira Ruiz-Heredia, Alejandro Martín-Muñoz, Santiago Barrio, Melissa M Berrien-Elliott, Jan Davidson-Moncada, Todd A Fehniger
Journal: Blood
Blood (2023) 142 (Supplement 1): 4813.
https://doi.org/10.1182/blood-2023-184986
Published: 2023
Journal Articles

Mutations Associated with Progression in Follicular Lymphoma Predict Inferior Outcomes in Newly Diagnosed Patients (Alliance 151303)

David A. Russler-Germain, Kilannin Krysiak, Cody Ramirez, Matthew Mosior, Marcus P. Watkins, Felicia Gomez, Zachary Skidmore, Lee Trani, Feng Gao, Susan M. Geyer, Amanda F. Cashen, Neha Mehta-Shah, Brad S. Kahl, Nancy L. Bartlett, Izidore S. Lossos, Eric D. Hsi, Peter Martin, John P. Leonard, Malachi Griffith, Obi L. Griffith, Todd A. Fehniger
Journal: Blood
Blood (2022) 140 (Supplement 1): 3543–3545.
https://doi.org/10.1182/blood-2022-157051
Published: 2022
Journal Articles

Putative Predictors of Response to WU-NK-101, an Allogeneic, Enhanced Memory (ML) Natural Killer (NK) Cell Therapy Product, for Relapsed/Refractory (R/R) Acute Myeloid Leukemia (AML)

Sergio Rutella, Amanda F. Cashen, John Muth, Mary Elizabeth Mathyer, Alun James Carter, Brunda Tumala, Laura Arthur, Kristann Magee, Paula Comune Pennacchi, Julian Gorrochategui, Vincent Petit, Daniel Primo, Dominique Blanchard, Michael Kiebish, Nupur Bhatnagar, David Boocock, Jayakumar Vadakekolathu, Matthew L Cooper, Melissa M. Berrien-Elliott, Jan K Davidson-Moncada, Todd A. Fehniger
Journal: Blood
Blood (2022) 140 (Supplement 1): 7400–7401.
https://doi.org/10.1182/blood-2022-157199
Published: 2022
Journal Articles

A Phase 1 Study of WU-NK-101 in Patients with Relapsed or Refractory (R/R) Acute Myeloid Leukemia (AML)

Amanda F. Cashen, Hongtao Liu, Monzr M. Al Malki, Joshua F. Zeidner, Matthew C. Foster, Angela Pannunzio, Brett Ramsey, Jan Baughman, John Muth, Ouiam Bakkacha, Eileen McNulty, Kenneth Jacobs, Jan K Davidson-Moncada, Andrew H Wei
Journal: Blood
Blood (2022) 140 (Supplement 1): 12740–12741.
https://doi.org/10.1182/blood-2022-158634
Published: 2022
Journal Articles

Phase I Study of Baricitinib Gvhd Prophylaxis in HLA-Matched, Peripheral Blood Allogeneic Hematopoietic Cell Transplant

Mark A. Schroeder, Jaebok Choi, Himachandana Atluri, Jordan Atkins, Melinda Harding, Jeremy Eisele, Feng Gao, Ramzi Abboud, Camille Abboud, Sr., Amanda F. Cashen, Matthew Christopher, Todd A. Fehniger, Francesca Ferraro, Armin Ghobadi, Meagan A. Jacoby, Iskra Pusic, Keith E Stockerl-Goldstein, Geoffrey L. Uy, Ravi Vij, Matthew J Walter, Peter Westervelt, John F. DiPersio
Journal: Blood
Blood (2022) 140 (Supplement 1): 1875–1876.
https://doi.org/10.1182/blood-2022-157214
Published: 2022
Journal Articles

Outcomes of DLBCL Patients Achieving Complete Remission after R-ICE Chemoimmunotherapy

Paolo F Caimi, Christine Auberle, Krishna Goparaju, Firas Baidoun, Amanda F. Cashen, Brian T. Hill
Journal: Blood
Blood (2022) 140 (Supplement 1): 381–383.
https://doi.org/10.1182/blood-2022-170752
Published: 2022
Journal Articles

Long-term outcomes for ibrutinib–rituximab and chemoimmunotherapy in CLL: updated results of the E1912 trial

Clinical Trials & Observations
Tait D. Shanafelt, Xin Victoria Wang, Curtis A. Hanson, Elisabeth M. Paietta, Susan O’Brien, Jacqueline Barrientos, Diane F. Jelinek, Esteban Braggio, Jose F. Leis, Cong Christine Zhang, Steven E. Coutre, Paul M. Barr, Amanda F. Cashen, Anthony R. Mato, Avina K. Singh, Michael P. Mullane, Richard F. Little, Harry Erba, Richard M. Stone, Mark Litzow, Martin Tallman, Neil E. Kay
Journal: Blood
Blood (2022) 140 (2): 112–120.
https://doi.org/10.1182/blood.2021014960
Published: 2022
Includes: Supplemental data
Journal Articles

Phase 1/dose expansion trial of brentuximab vedotin and lenalidomide in relapsed or refractory diffuse large B-cell lymphoma

Clinical Trials & Observations
Jeffrey P. Ward, Melissa M. Berrien-Elliott, Felicia Gomez, Jingqin Luo, Michelle Becker-Hapak, Amanda F. Cashen, Nina D. Wagner-Johnston, Kami Maddocks, Matthew Mosior, Mark Foster, Kilannin Krysiak, Alina Schmidt, Zachary L. Skidmore, Sweta Desai, Marcus P. Watkins, Anne Fischer, Malachi Griffith, Obi L. Griffith, Todd A. Fehniger, Nancy L. Bartlett
Journal: Blood
Blood (2022) 139 (13): 1999–2010.
https://doi.org/10.1182/blood.2021011894
Published: 2022
Includes: Supplemental data
Journal Articles

Donor memory-like NK cells persist and induce remissions in pediatric patients with relapsed AML after transplant

Clinical Trials & Observations
Jeffrey J. Bednarski, Clare Zimmerman, Melissa M. Berrien-Elliott, Jennifer A. Foltz, Michelle Becker-Hapak, Carly C. Neal, Mark Foster, Timothy Schappe, Ethan McClain, Patrick P. Pence, Sweta Desai, Samantha Kersting-Schadek, Pamela Wong, David A. Russler-Germain, Bryan Fisk, Wen-Rong Lie, Jeremy Eisele, Stephanie Hyde, Sima T. Bhatt, Obi L. Griffith, Malachi Griffith, Allegra A. Petti, Amanda F. Cashen, Todd A. Fehniger
Journal: Blood
Blood (2022) 139 (11): 1670–1683.
https://doi.org/10.1182/blood.2021013972
Published: 2022
Includes: Supplemental data
Journal Articles

Systemic IL-15 promotes allogeneic cell rejection in patients treated with natural killer cell adoptive therapy

Clinical Trials & Observations Brief Report
Melissa M. Berrien-Elliott, Michelle Becker-Hapak, Amanda F. Cashen, Miriam Jacobs, Pamela Wong, Mark Foster, Ethan McClain, Sweta Desai, Patrick Pence, Sarah Cooley, Claudio Brunstein, Feng Gao, Camille N. Abboud, Geoffrey L. Uy, Peter Westervelt, Meagan A. Jacoby, Iskra Pusic, Keith E. Stockerl-Goldstein, Mark A. Schroeder, John F. DiPersio, Patrick Soon-Shiong, Jeffrey S. Miller, Todd A. Fehniger
Journal: Blood
Blood (2022) 139 (8): 1177–1183.
https://doi.org/10.1182/blood.2021011532
Published: 2022
Includes: Supplemental data
Journal Articles

Measurable residual disease does not preclude prolonged progression-free survival in CLL treated with ibrutinib

Clinical Trials & Observations
Xin Victoria Wang, Curtis A. Hanson, Renee C. Tschumper, Connie E. Lesnick, Esteban Braggio, Elisabeth M. Paietta, Susan O’Brien, Jacqueline C. Barrientos, Jose Francisco Leis, Cong Christine Zhang, Steven E. Coutre, Paul M. Barr, Amanda F. Cashen, Anthony R. Mato, Avina K. Singh, Michael P. Mullane, Harry Erba, Richard Stone, Mark R. Litzow, Martin S. Tallman, Tait D. Shanafelt, Neil E. Kay
Journal: Blood
Blood (2021) 138 (26): 2810–2827.
https://doi.org/10.1182/blood.2020010146
Published: 2021
Includes: Supplemental data
Journal Articles

A Single-Arm, Open-Label, Pilot Study of the JAK1 Selective Inhibitor Itacitinib for the Prophylaxis of Graft-Versus-Host Disease and Cytokine Release Syndrome in T-Cell Replete Haploidentical Peripheral Blood Hematopoietic Cell Transplantation

Ramzi Abboud, Feng Gao, Michael P. Rettig, Jeremy Eisele, Leah Gehrs, Nichols Wallace, Camille Abboud, Sr., Peter Westervelt, Geoffrey L. Uy, Amanda F. Cashen, Matt Christopher, Armin Ghobadi, Meagan A. Jacoby, Iskra Pusic, Keith E. Stockerl-Goldstein, John F. DiPersio, Mark A. Schroeder
Journal: Blood
Blood (2021) 138 (Supplement 1): 100.
https://doi.org/10.1182/blood-2021-144591
Published: 2021