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Adam S Kittai
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Journal Articles

A Matching-Adjusted Indirect Comparison of Acalabrutinib with and without Obinutuzumab Versus Zanubrutinib in Treatment-Naïve Chronic Lymphocytic Leukemia

John N. Allan, Adam S Kittai, Dan James, Helen Ridge, Miguel Miranda, Alan Yong, Fady Fam, Jack Roos, Vikram Shetty, Matthew S. Davids, Alan Skarbnik
Journal: Blood
Blood (2023) 142 (Supplement 1): 6563.
https://doi.org/10.1182/blood-2023-178698
Published: 2023
Journal Articles

Coronado CLL : A Phase Ib/II Trial of Co mbination R p-3500 and O laparib in DNA Damage Repair Pathway D eficient Relapsed/Refract o ry C hronic L ymphocytic L eukemia

Boyu Hu, Adam S Kittai, Kenneth Boucher, Tony Pomicter, Deborah M. Stephens
Journal: Blood
Blood (2023) 142 (Supplement 1): 3286.
https://doi.org/10.1182/blood-2023-178381
Published: 2023
Journal Articles

Is CAR T a Drug or a Therapeutic Pathway? Systematic Review, (Re-)Estimation of Efficacy Endpoints and Metanalyses in Large B-Cell Lymphoma Real World Reports

Pier Luigi Zinzani, Rossana Di Staso, Beatrice Casadei, Frederick L. Locke, Michael D. Jain, Timothy Voorhees, Adam S Kittai, Mariana Bastos-Oreiro, Antonio Gutiérrez, Alejandro Martin Garcia-Sancho, Maria Jose Terol, Monica Mead, Michael J. Maranzano, Gloria Iacoboni, Pere Barba, Mi Kwon, Rebeca Bailen, Juan Luis Reguera, Agrima Mian, Brian T. Hill, Emmanuel Bachy, Franck Morschhauser, Roch Houot, Catherine Thieblemont, Steven Le Gouill, Riccardo Masetti, Davide Gori, Lisa Argnani
Journal: Blood
Blood (2023) 142 (Supplement 1): 6938.
https://doi.org/10.1182/blood-2023-178526
Published: 2023
Journal Articles

Extended Follow up of a Phase 2 Study of Early Intervention with Lenalidomide in Patients with High-Risk Chronic Lymphocytic Leukemia

Kerry A Rogers, Qiuhong Zhao, Seema A Bhat, John C. Byrd, Cara Grantier, Michael R. Grever, Corinne Hoffman, Adam S Kittai, Gerard Lozanski, Margaret S. Lucas, Lindsey Rike, Shanmugapriya Thangavadivel, William E. Carson III, Jennifer A. Woyach
Journal: Blood
Blood (2023) 142 (Supplement 1): 3272.
https://doi.org/10.1182/blood-2023-180308
Published: 2023
Journal Articles

Single-Cell RNA-Seq Analysis Reveals Distinct Tumor and Immunosuppressive T Cell Phenotypes in CLL Patients Treated with Ibrutinib

Shanmugapriya Thangavadivel, Shrilekha Misra, Samon Benrashid, Britten Gordon, Alexander He, Tzung-Huei Lai, Kerry A Rogers, Seema A Bhat, Adam S Kittai, John C. Byrd, James S. Blachly, Jennifer A. Woyach, Bradley Wayne Blaser
Journal: Blood
Blood (2023) 142 (Supplement 1): 3262.
https://doi.org/10.1182/blood-2023-186604
Published: 2023
Journal Articles

Predictors of Cytokine Release Syndrome and Neurotoxicity in Patients with Large B-Cell Lymphoma and Their Impact on Survival

Roni Shouval, Christopher Strouse, Soyoung Kim, Temitope Oloyede, Sairah Ahmed, Farrukh T. Awan, Veronika Bachanova, Talha Badar, Pere Barba, Amer M. Beitinjaneh, Amanda F Cashen, Bhagirathbhai Dholaria, Mahmoud Elsawy, Siddhartha Ganguly, Praveen Ramakrishnan Geethakumari, Uri Greenbaum, Hamza Hashmi, Laquisa C. Hill, Michael D. Jain, Tania Jain, Partow Kebriaei, Adam S Kittai, Frederick L. Locke, Premal D. Lulla, Elena Mead, Joseph P McGuirk, Alberto Mussetti, Taiga Nishihori, Amanda L. Olson, Martina Pennisi, Miguel-Angel Perales, Peter A. Riedell, Wael Saber, Sayeef Mirza, Margarida Magalhaes-Silverman, Elizabeth J. Shpall, Mohamed Sorror, Kitsada Wudhikarn, Cameron J. Turtle, Marcelo Pasquini, Amy Moskop
Journal: Blood
Blood (2023) 142 (Supplement 1): 355.
https://doi.org/10.1182/blood-2023-181181
Published: 2023
Journal Articles

Outcomes of Patients with Richter Transformation without Prior Chemoimmunotherapy for CLL/SLL: An International Multicenter Retrospective Study

Adam S Kittai, Ying Huang, Sarah Miller, John N. Allan, Seema A Bhat, David A. Bond, Danielle M Brander, John C. Byrd, Julio C Chavez, Elise A. Chong, Matthew S Davids, Alexey Danilov, Wei Ding, Mark R Dowling, Kaitlyn M. Dvorak-Kornaus, Hannah Freedman, Paul J Hampel, Carrie I Ho, Steven R Hwang, Prioty Islam, Nitin Jain, Matthew Matasar, Cecelia Miller, Erin M Parry, Kari G. Rabe, Manoj Rai, Phil Raess, Lindsey E. Roeker, Joanna M. Rhodes, Kerry A Rogers, Aditi Saha, Jake Schade, Hamish S Scott, Mazyar Shadman, Geoffrey P. Shouse, Alan Skarbnik, Stephen E Spurgeon, Deborah M. Stephens, Meghan C. Thompson, Philip A. Thompson, Yucai Wang, William G. Wierda, Max Yano, Omer Zulfa, Jennifer A. Woyach
Journal: Blood
Blood (2023) 142 (Supplement 1): 497.
https://doi.org/10.1182/blood-2023-182114
Published: 2023
Journal Articles

T Cell Dysfunction and Exhaustion in Patients with CLL: The Impact of Long Term Ibrutinib Treatment

Shanmugapriya Thangavadivel, Charlene Mao, Meixiao Long, Shrilekha Misra, Samon Benrashid, Britten Gordon, Alexander He, Tzung-Huei Lai, Kerry A Rogers, Seema A Bhat, Adam S Kittai, John C. Byrd, Jennifer A. Woyach
Journal: Blood
Blood (2023) 142 (Supplement 1): 4631.
https://doi.org/10.1182/blood-2023-189755
Published: 2023
Journal Articles

Counting Chromosome Abnormalities in Chronic Lymphocytic Leukemia: Comparison of Iscn 2020 and MDS International Working Group Guidelines for Establishing Karyotype Complexity

Cecelia Miller, Ying Huang, Adam S Kittai, Seema A Bhat, Kerry A Rogers, Michael R. Grever, Jennifer A. Woyach, Matthew R Avenarius
Journal: Blood
Blood (2023) 142 (Supplement 1): 1906.
https://doi.org/10.1182/blood-2023-180807
Published: 2023
Journal Articles

Targeting Covalent and Non-Covalent Btki-Resistant CLL Using the Dual Irreversible/Reversible 4 th Generation BTK Inhibitor LP-168

Britten Gordon, Elizabeth Muhowski, Janani Ravikrishnan, Samon Benrashid, Andrew Mitchell, Alexander He, Shrilekha Misra, Tzung-Huei Lai, Shanmugapriya Thangavadivel, Alexander Marr, Lianbo Yu, Brandi Walker, Elizabeth Perry, Kerry A Rogers, Adam S Kittai, Seema A Bhat, John C. Byrd, Deepa Sampath, Rosa Lapalombella, Weiguo Han, Neil E. Kay, Yi Chen, Fenlai Tan, Stephen P. Anthony, Yu Chen, Jennifer A. Woyach
Journal: Blood
Blood (2023) 142 (Supplement 1): 416.
https://doi.org/10.1182/blood-2023-178259
Published: 2023
Journal Articles

The PKC-β Inhibitor MS-553 Displays Preclinical Efficacy in BTK Inhibitor Resistant Chronic Lymphocytic Leukemia

Britten Gordon, Elizabeth Muhowski, Janani Ravikrishnan, Shanmugapriya Thangavadivel, Samon Benrashid, Alexander He, Shrilekha Misra, Tzung-Huei Lai, Alexander Marr, Lianbo Yu, Brandi Walker, Elizabeth Perry, Nicole R. Grieselhuber, Kerry A Rogers, James S. Blachly, Adam S Kittai, Seema A Bhat, John C. Byrd, Michael Niesman, Kai Zhang, Deepa Sampath, Jennifer A. Woyach
Journal: Blood
Blood (2023) 142 (Supplement 1): 2260.
https://doi.org/10.1182/blood-2023-182024
Published: 2023
Journal Articles

Real-World Outcomes of CD19CAR T Cell Therapy in Adult Patients with Relapsed Refractory Transformed Indolent Lymphoma

Swetha Kambhampati, Reid W. Merryman, Yan Wang, Evandro Bezerra, Timothy Voorhees, Ayo S Falade, Madhav R Seshadri, Megumi Bailey, Neil Bailey, Krish Patel, Charalambos Andreadis, Adam S Kittai, Caron A Jacobson, Joycelynne Michelle Palmer, Annette Brown, Alex F. Herrera, L. Elizabeth Budde
Journal: Blood
Blood (2023) 142 (Supplement 1): 3511.
https://doi.org/10.1182/blood-2023-182467
Published: 2023
Journal Articles

Anti-CD19 Chimeric Antigen Receptor T-Cell Therapy for Richter's Transformation: An International Multicenter Retrospective Study

Adam S Kittai, David A. Bond, Ying Huang, Seema A Bhat, Emily Blyth, John C. Byrd, Julio C Chavez, Matthew S Davids, Jamie P Dela Cruz, Mark R Dowling, Caitlyn Duffy, Carrie I Ho, Caron A Jacobson, Samantha M. Jaglowski, Nitin Jain, Kevin H Lin, Christine McCarthy, Erin M Parry, Manoj Rai, Kerry A Rogers, Aditi Saha, Levanto Schachter, Hamish Scott, Jayastu Senapati, Mazyar Shadman, Tanya Siddiqi, Deborah M. Stephens, Vinay Vanguru, William G. Wierda, Omer Zulfa, Jennifer A. Woyach, Philip A. Thompson
Journal: Blood
Blood (2023) 142 (Supplement 1): 108.
https://doi.org/10.1182/blood-2023-180858
Published: 2023
Journal Articles

Safety, Efficacy and T-Cell Predictive Biomarkers in a Phase I Trial of Copanlisib+Nivolumab in Patients with Richter's Transformation (RT) or Transformed Non-Hodgkin Lymphoma (tNHL)

Geoffrey P. Shouse, Leslie L. Popplewell, Alex Muir, Tanya Siddiqi, Alex F. Herrera, Olga Danilova, Sandrine Puverel, Lili Wang, Adam S Kittai, Lu Chen, Matthew S Davids, Alexey Danilov
Journal: Blood
Blood (2023) 142 (Supplement 1): 1730.
https://doi.org/10.1182/blood-2023-182559
Published: 2023
Journal Articles

Initial Results of a Phase 2 Study of Venetoclax Added to Ibrutinib to Eliminate Ibrutinib Resistance Mutations in CLL

Kerry A Rogers, Eric McLaughlin, Lai Wei, Seema A Bhat, Arianna Crouse, Michael R. Grever, Dan Jones, Adam S Kittai, Gerard Lozanski, Mollie Moran, Mark Reid, Ellen J Sass, Swetha Suresh, John C. Byrd, Jennifer A. Woyach
Journal: Blood
Blood (2023) 142 (Supplement 1): 1899.
https://doi.org/10.1182/blood-2023-180294
Published: 2023
Journal Articles

Initial Results of a Phase 1 Dose Escalation Study of LP-168, a Novel Covalent and Non-Covalent Next-Generation Inhibitor of Bruton's Tyrosine Kinase

Jennifer A. Woyach, Deborah M. Stephens, Danielle M Brander, Adam S Kittai, Boyu Hu, Andrea Sitlinger, Emily K Curran, Fenlai Tan, Yi Chen, Stephen P. Anthony, Yu Chen, John C. Byrd
Journal: Blood
Blood (2023) 142 (Supplement 1): 328.
https://doi.org/10.1182/blood-2023-186432
Published: 2023
Journal Articles

A Phase I Trial of PI3Kαδ Inhibitor Copanlisib in Combination with Nivolumab in Patients with Richter's Transformation (RT) or Transformed Non-Hodgkin Lymphoma (tNHL)

Geoffrey Shouse, Tanya Siddiqi, Leslie L. Popplewell, Alexandra Muir, Ivana Melgar, Kirsten Orand, Brandy Gonzalez, Sandrine Puverel, Lili Wang, Adam S Kittai, Lu Chen, Matthew S. Davids, Alexey V Danilov
Journal: Blood
Blood (2022) 140 (Supplement 1): 6633–6634.
https://doi.org/10.1182/blood-2022-160157
Published: 2022
Journal Articles

Impact of a Validated Composite Comorbidity Score on Outcomes in Patients Treated with CAR T-Cell Therapy for Diffuse Large B Cell Lymphoma (DLBCL): A Multicenter Real-World Evidence (RWE) Study

Geoffrey Shouse, Andy Kaempf, Max J. Gordon, David Yashar, Audrey M. Sigmund, Gordon Smilnak, Steven M. Bair, Agrima Mian, Lindsey A. Fitzgerald, Amneet Bajwa, Samantha Jaglowski, Neil Bailey, Mazyar Shadman, Krish Patel, Deborah M. Stephens, Manali Kamdar, Brian T. Hill, Jordan Gauthier, Reem Karmali, Loretta J. Nastoupil, Adam S Kittai, Alexey V Danilov
Journal: Blood
Blood (2022) 140 (Supplement 1): 2048–2050.
https://doi.org/10.1182/blood-2022-169872
Published: 2022
Journal Articles

Treatment of CLL-Associated Autoimmune Cytopenias and Outcomes in a Single Institution Cohort Study

Isaac Esplin, Ying Huang, Seema A. Bhat, Cara Grantier, Michael R. Grever, Corinne Hoffman, Adam S Kittai, Margaret S. Lucas, Mollie E. Moran, Mark Reid, Swetha Suresh, Jennifer A. Woyach, Kerry A. Rogers
Journal: Blood
Blood (2022) 140 (Supplement 1): 4166–4168.
https://doi.org/10.1182/blood-2022-167314
Published: 2022
Journal Articles

Characterizing the Development of Secondary Myelodysplastic Syndrome (MDS) with Antecedent or Concurrent Chronic Lymphocytic Leukemia (CLL) in the Era of Small Molecule Inhibitors for the Treatment of CLL

Kristin L Koenig, Prachi Jain, Ying Huang, Kerry A. Rogers, Seema A. Bhat, Jennifer A. Woyach, Michael R. Grever, Uma Borate, Alice S. Mims, Daniel Jones, Cecelia Miller, James S. Blachly, Adam S Kittai
Journal: Blood
Blood (2022) 140 (Supplement 1): 4071–4073.
https://doi.org/10.1182/blood-2022-168274
Published: 2022