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Journal Articles

PIKfyve inhibition in myeloma disrupts autophagy and the lysosome, increasing MHC expression and cholesterol metabolism

Cecilia Bonolo De Campos, Ruijuan He, Tessa Josephine Pelino, Dor David Abelman, Zhihua Li, Daniel K C Lee, Ding Yan Wang, Michael St. Paul, Jeffrey Bruce, Craig D Simpson, Leanne Wybenga-Groot, Michael F. Moran, Rodger E Tiedemann, Trevor Pugh, Tak W. Mak, Olga Issakova, Nikolai Sepetov, Suzanne Trudel, A Keith Stewart

Blood blood.2025030061.

https://doi.org/10.1182/blood.2025030061

Published: 2025

Includes: Supplemental data

Journal Articles

Umbilical cord blood microtransplantation improves the prognosis of patients with relapsed/refractory myeloid tumors who are not candidates for intensive therapy: Clinical efficacy and mechanism analysis

Chenxiao Du, Shiqin Luo, Yuhui Zhang, Guangshuai Teng, Yifan Duan, Yan Wang, Yanqi Li, Huiqin Zhang, Yuan Zhou, Yajing Chu, Weiping Yuan, Jie Bai

Blood (2025) 146 (Supplement 1): 7656.

https://doi.org/10.1182/blood-2025-7656

Published: 2025

Journal Articles

Ruxolitinib mitigates interferon-induced autoimmune toxicity: Clinical insights from a 465-patient MPN Cohort Retrospective study

Guangshuai Teng, Yuhui Zhang, Anna Li, Chenxiao Du, Yan Wang, Yanqi Li, Lan Peng, Huiqin Zhang, Yifan Duan, Yuan Zhou, Weiping Yuan, Jie Bai

Blood (2025) 146 (Supplement 1): 2044.

https://doi.org/10.1182/blood-2025-2044

Published: 2025

Journal Articles

A prospecitive, multicenter study of chidamide in adult patients with refractory primary immune thrombocytopenia

Lu Sun, Juan Wang, Yan Wang, Hongyu Zhao, Ruirong Xu, Yu Hou, Ming Hou

Blood (2025) 146 (Supplement 1): 3043.

https://doi.org/10.1182/blood-2025-3043

Published: 2025

Journal Articles

Total marrow and lymphoid irradiation (2000 cGy) together with cyclophosphamide and etoposide prior to allogeneic hematopoietic cell transplantation is an effective regimen for Relapsed/Refractory leukemia, with low non-relapse mortality

Blood (2025) 146 (Supplement 1): 2441.

https://doi.org/10.1182/blood-2025-2441

Published: 2025

Journal Articles

Gut microbiota alterations in myelodysplastic neoplasms are associated with immune dysfunction and the therapeutic mechanism of hypomethylating agents

Zhongxun Shi, Fei Huang, Yu Chen, Chun Qiao, Rong Wang, Yan Wang, Jianyong Li, Lei Fan, Wenyi Shen

Blood (2025) 146 (Supplement 1): 7362.

https://doi.org/10.1182/blood-2025-7362

Published: 2025

Journal Articles

Hematopoietic JAK2V617F mutation increases susceptibility to atrial fibrillation via NLRP3 inflammasome activation in macrophages

Guangshuai Teng, Ke Shang, Yuhui Zhang, Yifan Duan, Chenxiao Du, Yan Wang, Yanqi Li, Huiqin Zhang, Xiaojing Wei, Yuan Zhou, Weiping Yuan, Jie Bai

Blood (2025) 146 (Supplement 1): 634.

https://doi.org/10.1182/blood-2025-634

Published: 2025

Journal Articles

Low expression of TMSB10 in bone marrow in MDS patients with T cell large granular lymphocytic proliferation is associated with improved immune tolerance status of T cells and disease prognosis: Clinical data and single-cell sequencing analysis

Chenxiao Du, Shiqin Luo, Yuhui Zhang, Guangshuai Teng, Yifan Duan, Yan Wang, Yanqi Li, Huiqin Zhang, Yuan Zhou, Yajing Chu, Weiping Yuan, Jie Bai

Blood (2025) 146 (Supplement 1): 5020.

https://doi.org/10.1182/blood-2025-5020

Published: 2025

Journal Articles

Incidence, risk factors, and survival impact of secondary myelofibrosis in patients with myeloproliferative neoplasms in the real world: A nested case-control study

Yuhui Zhang, Guangshuai Teng, Yunhan Zhao, Yifan Duan, Ke Shang, Chenxiao Du, Yan Wang, Yanqi Li, Huiqin Zhang, Xiaojing Wei, Zonghong Shao, Yuan Zhou, Weiping Yuan, Jie Bai

Blood (2025) 146 (Supplement 1): 7337.

https://doi.org/10.1182/blood-2025-7337

Published: 2025

Journal Articles

Phase I study of NPB5005-V283 in patients with relapsed/refractory multiple myeloma

Wanyan Ouyang, William Comrie, Shiwei Jin, Mengmeng Pan, Jie Xu, Yi Tao, Yuanfang Liu, Yan Wang, Weiping Zhang, Xueqiong Song, Cong Wang, Wenshan Hao, Jian-Qing Mi

Blood (2025) 146 (Supplement 1): 2295.

https://doi.org/10.1182/blood-2025-2295

Published: 2025

Journal Articles

Analysis of clinical and laboratory characteristics of ALL with atypical BCR::ABL1 fusion genes

Yanbo Nie, Hong Zhang, Liying Liu, Yue Hou, Chuting Zhao, Yan Wang, Tongcui An, Yani Lin, Kun Ru

Blood (2025) 146 (Supplement 1): 6885.

https://doi.org/10.1182/blood-2025-6885

Published: 2025

Journal Articles

Fully Human anti-GPRC5D CAR T-Cell Therapy RD118 Induces Durable Remissions in Relapsed/Refractory Multiple Myeloma

Mengmeng Pan, Di Wang, Jie Xu, Shiwei Jin, Yan Wang, Yi Tao, Yuanfang Liu, Wanyan Ouyang, Xiangqin Weng, Hongmei Yi, Yu Huang, Xinmei Cao, Shuhua Li, Fuyuan Zhang, Weiping Zhang, Chunrui Li, Jian-Qing Mi

Blood blood.2025030559.

https://doi.org/10.1182/blood.2025030559

Published: 2025

Includes: Supplemental data

Journal Articles

Targeting WDR5/ATAD2 signaling by the CK2/IKAROS axis demonstrates therapeutic efficacy in T-ALL

Qi Han, Yan Gu, Huimin Xiang, Linyao Zhang, Yan Wang, Chan Yang, Jun Li, Chelsea Steiner, Rosa Lapalombella, Jennifer A. Woyach, Yiping Yang, Sinisa Dovat, Chunhua Song, Zheng Ge

Blood (2025) 145 (13): 1407–1421.

https://doi.org/10.1182/blood.2024024130

Published: 2025

Includes: Supplemental data

Journal Articles

Characterization of Hemophagocytic Lymphohistiocytosis Associated with Myeloid Neoplasms at Single-Cell Resolution

Ke Shang, Guangshuai Teng, Yuhui Zhang, Yifan Duan, Chenxiao Du, Yan Wang, Huiqin Zhang, Xuelian Cheng, Yuan Zhou, Yajing Chu, Weiping Yuan, Jie Bai

Blood (2024) 144 (Supplement 1): 4101.

https://doi.org/10.1182/blood-2024-206981

Published: 2024

Journal Articles

Clinical Characterization of Myeloid Neoplasms Patients with Fanconi Anemia Gene Mutations

Yuhui Zhang, Guangshuai Teng, Yifan Duan, Chenxiao Du, Yan Wang, Huiqin Zhang, Xin Hu, Yunhan Zhao, Yuan Zhou, Weiping Yuan, Jie Bai

Blood (2024) 144 (Supplement 1): 3175.

https://doi.org/10.1182/blood-2024-207513

Published: 2024

Journal Articles

The Immune Inhibitory Hematopoietic Adaptor Protein Hacs1(Sly2) Suppresses the Proinflammatory Macrophage Function Contributing to Multiple Myeloma Progression

Ding Yan Wang, Ming Liu, Jamie Li, Raymond Qu, Keva Garg, Yuan Gao, Xinmiao Andrew Yang, Leqi Shen, Jingdong Wu, Xiaoyuan Liu, Derek Shiqi Xu, Cecilia Bonolo De Campos, Jinyi Zhang, Anthony Gramolini, Katherine Siminovitch, Xiao-Yan Wen, A. Keith Stewart

Blood (2024) 144 (Supplement 1): 3271.

https://doi.org/10.1182/blood-2024-209501

Published: 2024

Journal Articles

Targeted Therapy with CX4945 Biomimetic Nanodrug Delivery System for High-Risk B-Cell Acute Lymphoblastic Leukemia

Yan Wang, Fei Wang, Haoan Wu, Qi Han, Yu Zhang, Chunhua Song, Zheng Ge

Blood (2024) 144 (Supplement 1): 2788.

https://doi.org/10.1182/blood-2024-202461

Published: 2024

Journal Articles

Hematopoietic JAK2 V617F Mutation Increases Risk for Atrial Fibrillation

Guangshuai Teng, Ke Shang, Yuhui Zhang, Yifan Duan, Chenxiao Du, Yan Wang, Huiqin Zhang, Weiping Yuan, Yuan Zhou, Jie Bai

Blood (2024) 144 (Supplement 1): 5740.

https://doi.org/10.1182/blood-2024-206325

Published: 2024

Journal Articles

Real-World Effectiveness of Ravulizumab Among Adults with Atypical Hemolytic Uremic Syndrome (aHUS) Who Switched to Ravulizumab within 3 Months of Eculizumab Treatment: A Physician Panel-Based Chart Review Study (aHUS IMPACT)

Shruti Chaturvedi, Yan Wang, Moh-Lim Ong, Arpita Nag, Rui Song, Lynn Huynh, Jordan A. Burdeau, Mei Sheng Duh, Ramy Magdy Hanna

Blood (2024) 144 (Supplement 1): 2613.

https://doi.org/10.1182/blood-2024-194225

Published: 2024

Journal Articles

Outpatient Administration of Brexucabtagene Autoleucel (brexu-cel) for Acute Lymphoblastic Leukemia (ALL) and Mantle Cell Lymphoma (MCL) Is Safe and Feasible

Tamer Othman, John H. Baird, Yan Wang, Stacy Pak, Ibrahim Aldoss, Ji-Lian Cai, Alexey Danilov, Tycel J. Phillips, Vaibhav Agrawal, Karamjeet S Sandhu, Matthew Mei, Paul B. Koller, Joycelynne Michelle Palmer, Stephen J. Forman, Lihua E. Budde, Ahmed Aribi

Blood (2024) 144 (Supplement 1): 2278.

https://doi.org/10.1182/blood-2024-207085

Published: 2024

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PIKfyve inhibition in myeloma disrupts autophagy and the lysosome, increasing MHC expression and cholesterol metabolism

Umbilical cord blood microtransplantation improves the prognosis of patients with relapsed/refractory myeloid tumors who are not candidates for intensive therapy: Clinical efficacy and mechanism analysis

Ruxolitinib mitigates interferon-induced autoimmune toxicity: Clinical insights from a 465-patient MPN Cohort Retrospective study

A prospecitive, multicenter study of chidamide in adult patients with refractory primary immune thrombocytopenia

Total marrow and lymphoid irradiation (2000 cGy) together with cyclophosphamide and etoposide prior to allogeneic hematopoietic cell transplantation is an effective regimen for Relapsed/Refractory leukemia, with low non-relapse mortality

Gut microbiota alterations in myelodysplastic neoplasms are associated with immune dysfunction and the therapeutic mechanism of hypomethylating agents

Hematopoietic JAK2V617F mutation increases susceptibility to atrial fibrillation via NLRP3 inflammasome activation in macrophages

Low expression of TMSB10 in bone marrow in MDS patients with T cell large granular lymphocytic proliferation is associated with improved immune tolerance status of T cells and disease prognosis: Clinical data and single-cell sequencing analysis

Incidence, risk factors, and survival impact of secondary myelofibrosis in patients with myeloproliferative neoplasms in the real world: A nested case-control study

Phase I study of NPB5005-V283 in patients with relapsed/refractory multiple myeloma

Analysis of clinical and laboratory characteristics of ALL with atypical BCR::ABL1 fusion genes

Fully Human anti-GPRC5D CAR T-Cell Therapy RD118 Induces Durable Remissions in Relapsed/Refractory Multiple Myeloma

Targeting WDR5/ATAD2 signaling by the CK2/IKAROS axis demonstrates therapeutic efficacy in T-ALL

Characterization of Hemophagocytic Lymphohistiocytosis Associated with Myeloid Neoplasms at Single-Cell Resolution

Clinical Characterization of Myeloid Neoplasms Patients with Fanconi Anemia Gene Mutations

The Immune Inhibitory Hematopoietic Adaptor Protein Hacs1(Sly2) Suppresses the Proinflammatory Macrophage Function Contributing to Multiple Myeloma Progression

Targeted Therapy with CX4945 Biomimetic Nanodrug Delivery System for High-Risk B-Cell Acute Lymphoblastic Leukemia

Hematopoietic JAK2 V617F Mutation Increases Risk for Atrial Fibrillation

Real-World Effectiveness of Ravulizumab Among Adults with Atypical Hemolytic Uremic Syndrome (aHUS) Who Switched to Ravulizumab within 3 Months of Eculizumab Treatment: A Physician Panel-Based Chart Review Study (aHUS IMPACT)

Outpatient Administration of Brexucabtagene Autoleucel (brexu-cel) for Acute Lymphoblastic Leukemia (ALL) and Mantle Cell Lymphoma (MCL) Is Safe and Feasible

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