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Nikolai Sepetov
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Journal Articles

PIKfyve inhibition in myeloma disrupts autophagy and the lysosome, increasing MHC expression and cholesterol metabolism

Open Access
Cecilia Bonolo De Campos, Ruijuan He, Tessa Josephine Pelino, Dor David Abelman, Zhihua Li, Daniel K C Lee, Ding Yan Wang, Michael St. Paul, Jeffrey Bruce, Craig D Simpson, Leanne Wybenga-Groot, Michael F. Moran, Rodger E Tiedemann, Trevor Pugh, Tak W. Mak, Olga Issakova, Nikolai Sepetov, Suzanne Trudel, A Keith Stewart
Journal: Blood
Blood blood.2025030061.
https://doi.org/10.1182/blood.2025030061
Published: 2025
Includes: Supplemental data
Journal Articles

PIK-001 a Novel Small Molecule Inhibitor of Pikfyve for Treatment of Multiple Myeloma (MM)

Free
A. Keith Stewart, Zhihua Li, Olga Issakova, Nikolai Sepetov, Suzanne Trudel
Journal: Blood
Blood (2021) 138 (Supplement 1): 1602.
https://doi.org/10.1182/blood-2021-151208
Published: 2021
Journal Articles

"Direct to Drug" Screening As a Route to Individualized Therapy in Multiple Myeloma

Free
Nathalie Meurice, PhD, Joachim L Petit, PhD, Cecilia Bonolo De Campos, PhD, Alysia N Polito, BS, Ilsel D Lopez Armenta, BS, Gregory J Ahmann, BS, Laura Ann Bruins, BS, Joseph R Mikhael, MD FRCPC, MD, Craig B. Reeder, MD, Angela A Mayo, MS, PA-C, P. Leif Bergsagel, MD, Rafael Fonseca, MD, Nikolai Sepetov, PhD, Sergei Romanov, PhD, A. Keith Stewart, MBChB, MBA
Journal: Blood
Blood (2017) 130 (Supplement 1): 3080.
https://doi.org/10.1182/blood.V130.Suppl_1.3080.3080
Published: 2017
Journal Articles

PIKfyve Inhibitors for the Treatment of Multiple Myeloma

Free
Cecilia Bonolo De Campos, PhD, Yuan Xiao Zhu, PhD, Chang-Xin Shi, PhD, Laura Ann Bruins, BS, Joachim L Petit, PhD, Alysia N Polito, BS, Meaghen E Sharik, BS, Caleb K Stein, MS, Gregory J Ahmann, BS, Ilsel D Lopez Armenta, BS, Nikolai Sepetov, PhD, Sergei Romanov, PhD, P. Leif Bergsagel, MD, Marta Chesi, PhD, Nathalie Meurice, PhD, A. Keith Stewart, MBChB, MBA
Journal: Blood
Blood (2017) 130 (Supplement 1): 4423.
https://doi.org/10.1182/blood.V130.Suppl_1.4423.4423
Published: 2017