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Journal Articles

Firicabtagene autoleucel (firi-cel), a CD22-directed CAR T-cell therapy, for patients with relapsed/refractory large B-cell lymphoma: Results from the phase 2 study (FIRCE-1 Trial)

Free
Matthew Frank, David Qualls, Armin Ghobadi, Jordan Gauthier, Michael Tees, Luke Mountjoy, Joseph McGuirk, Sattva Neelapu, Reem Karmali, Iris Isufi, Brian Hill, Craig Sauter, Catherine Diefenbach, Jay Spiegel, Lizamarie Bachier-Rodriguez, Monalisa Ghosh, Nirav Shah, Rahul Lakhotia, Francisco Hernandez-Ilizaliturri, Anuja Abhyankar, Elise Chong, Matthew Schwede, Krish Patel, Olalekan Oluwole, John Baird, Nathan Denlinger, Farrukh Awan, Michael Jain, John Timmerman, Cesar Sanchez, Muthu Kumaran, Jean Yared, Jon Arnason, Ishan Tatake, Usama Gergis, Peter Riedell, Keith Pratz, Nirali Shah
Journal: Blood
Blood (2025) 146 (Supplement 1): 667.
https://doi.org/10.1182/blood-2025-667
Published: 2025
Journal Articles

Pirtobrutinib in Relapsed/Refractory (R/R) Mantle Cell Lymphoma (MCL): Final update from the Phase 1/2 BRUIN study

Free
Michael Wang, Jonathon Cohen, Nirav Shah, Wojciech Jurczak, Pier Luigi Zinzani, Chan Cheah, Chaitra Ujjani, Youngil Koh, Won Seog Kim, Sunita Dwivedy Nasta, Ian Flinn, Benoit Tessoulin, Shuo Ma, Alvaro Alencar, David Lewis, Jennifer Woyach, Kami Maddocks, Krish Patel, Yucai Wang, Joanna Rhodes, Constantine Tam, John Seymour, Hirokazu Nagai, Julie Vose, Bita Fakhri, Marc Hoffmann, Francisco Hernandez-Ilizaliturri, Andrew Zelenetz, Anita Kumar, Talha Munir, Donald Tsai, Paolo Abada, Minna Balbas, Jian Li, Ying (denise) Wang, Lindsey Roeker, Toby Eyre
Journal: Blood
Blood (2025) 146 (Supplement 1): 665.
https://doi.org/10.1182/blood-2025-665
Published: 2025
Journal Articles

Pirtobrutinib in Relapsed/Refractory (R/R) Waldenström macroglobulinemia (WM): Up to 5 years of follow-up from the Phase 1/2 BRUIN study

Free
Chan Cheah, Manish Patel, Toby Eyre, Wojciech Jurczak, David Lewis, Thomas Gastinne, Shuo Ma, Jonathon Cohen, Krish Patel, Jennifer Brown, Lydia Scarfo, Talha Munir, Ewa Lech-Maranda, Marc Hoffmann, Chaitra Ujjani, Bita Fakhri, Michael Wang, Koji Izutsu, Hirokazu Nagai, Constantine Tam, Joanna Rhodes, Julie Vose, Matthew McKinney, James Gerson, Minal Barve, Bryone Kuss, Youngil Koh, Aisling Barrett, Steven Treon, Jorge Castillo, John Seymour, Amy Ruppert Stark, Samuel McNeely, Richard Walgren, Donald Tsai, Katherine Bao, Binoj Chandrasekharan Nair, Jennifer Woyach, Lia Palomba
Journal: Blood
Blood (2025) 146 (Supplement 1): 226.
https://doi.org/10.1182/blood-2025-226
Published: 2025
Journal Articles

Outpatient (OP) use of lisocabtagene maraleucel (liso-cel) in patients (Pts) with relapsed or refractory (R/R) large B-cell lymphoma (LBCL): Real-world data from the CIBMTR registry

Free
Krish Patel, Matthew Lunning, Konstantinos Sdrimas, Minoo Battiwalla, Uttam Rao, Yi Lin, Sami Ibrahimi, Jennifer L. Crombie, Sairah Ahmed, Iris Isufi, Matthew Frigault, David Bernasconi, Debasmita Roy, Marcelo Pasquini, Bradley D. Hunter
Journal: Blood
Blood (2025) 146 (Supplement 1): 5482.
https://doi.org/10.1182/blood-2025-5482
Published: 2025
Journal Articles

Pirtobrutinib in post-cbtki CLL/SLL: Final update from the Phase 1/2 BRUIN study with more than 5 years follow-up

Free
William Wierda, Jennifer Brown, Paolo Ghia, Lindsey Roeker, Krish Patel, Toby Eyre, Talha Munir, Ewa Lech-Maranda, Nicole Lamanna, Constantine Tam, John Seymour, Benoit Tessoulin, Nirav Shah, Chaitra Ujjani, Bita Fakhri, Catherine Coombs, Ian Flinn, Manish Patel, Sunita Dwivedy Nasta, Jonathon Cohen, Alvaro Alencar, Chan Cheah, Shuo Ma, Joanna Rhodes, Deepa Jagadeesh, Pier Luigi Zinzani, Anders Österborg, Koji Izutsu, Noriko Fukuhara, Donald Tsai, Paolo Abada, Minna Balbas, Jian Li, Ying (denise) Wang, Wojciech Jurczak, Jennifer Woyach
Journal: Blood
Blood (2025) 146 (Supplement 1): 2115.
https://doi.org/10.1182/blood-2025-2115
Published: 2025
Journal Articles

Biomarker correlates of clinical outcomes from a global Phase 1b study of JNJ-90014496, CD20/CD19 bi-specific chimeric antigen receptor (CAR) T-cell therapy for patients with large B-cell lymphoma (LBCL)

Free
Mahipal Suraneni, Da Yin, Dianna Wu, Daksh Thaper, Shajo Kunnath-Velayudhan, Jianmei Wu, Alfredo Perales Puchalt, Melissa Beelen, Julie Larsen, Leen Slaets, Arnob Banerjee, Donne Bennett Caces, Jacqueline Bussolari, Luke Mountjoy, Joanna Rhodes, Jacob Christensen, Martin Hutchings, Matthew Ku, Krish Patel, Vicki Plaks
Journal: Blood
Blood (2025) 146 (Supplement 1): 568.
https://doi.org/10.1182/blood-2025-568
Published: 2025
Journal Articles

Eculizumab vs control therapies in paroxysmal nocturnal hemoglobinuria: A meta-analysis of six randomized trials

Free
Anika Goel, Krish Patel, Arun Kumar Maloth, Sai Varun Reddy, Neel Parikh, Oorvi Gupta, Ammar Elgadi, Satya Ashray Guduru, Arysha Monis, Teja Sureddi, Ummul Asfeen, Malik saad Hayat
Journal: Blood
Blood (2025) 146 (Supplement 1): 6443.
https://doi.org/10.1182/blood-2025-6443
Published: 2025
Journal Articles

Two-year update of ZUMA-2 Cohort 3: Brexucabtagene autoleucel (Brexu-cel) in patients (pts) with relapsed/refractory mantle cell lymphoma (R/R MCL) who had not received prior Bruton tyrosine kinase inhibitor (BTKi) therapy

Free
Tom Van Meerten, Marie José Kersten, Gloria Iacoboni, Georg Hess, Pim Mutsaers, Alejandro Martin Garcia-Sancho, Andre Goy, Eva Gine, Brian Hill, Wen-Kai Weng, Martin Dreyling, Patrick Reagan, Krish Patel, Ahmed Galal, Charles Herbaux, Robin Sanderson, Dan Zheng, Sabina Adhikary, Wangshu Zhang, Rita Damico Khalid, Ioana Kloos, Michael Wang
Journal: Blood
Blood (2025) 146 (Supplement 1): 1799.
https://doi.org/10.1182/blood-2025-1799
Published: 2025
Journal Articles

Mortality trends in patients with mantle cell lymphoma with or without a COVID-19 diagnosis

Free
Krish Patel, Essam Ibrahim, Yi Han, Anna Teschemaker, Victoria Otero, Anouchka Chelles
Journal: Blood
Blood (2025) 146 (Supplement 1): 8055.
https://doi.org/10.1182/blood-2025-8055
Published: 2025
Journal Articles

A first-in-human Phase 1 trial of LY4152199, a B-cell activation factor receptor (BAFF-R) T-cell engager bispecific antibody, in patients with previously treated B-cell malignancies (BAF_FRontier-1 Trial in Progress)

Free
Krish Patel, Jennifer Crombie, Tycel Phillips, Michael Dickinson, Toby Eyre, Chan Cheah, Stephen Schuster, Nirav Shah, Georg Lenz, Laurie Sehn, Donald Tsai, Erica Johnston, Sonya Chapman, Hongmei Han, Minna Balbas, Ching Ching Leow, Gilles Salles
Journal: Blood
Blood (2025) 146 (Supplement 1): 5524.
https://doi.org/10.1182/blood-2025-5524
Published: 2025
Journal Articles

Optimizing processes for adverse event management for bispecific antibodies for diffuse large b-cell lymphoma in community practice: Insights from a quality improvement initiative

Free
Krish Patel, Joshua Brody, M. Sarfraz Nawaz, Jeffrey Bubis, Andy Chen, Edward Pearson, Emily Zyborowicz, Jeffrey Carter, Cherilyn Heggen, Shelby Sullivan, Lindsay Gurska
Journal: Blood
Blood (2025) 146 (Supplement 1): 6183.
https://doi.org/10.1182/blood-2025-6183
Published: 2025
Journal Articles

Diverse preferences for treatment options in relapsed/refractory (R/R) follicular lymphoma (FL): Survey results from patients in the United States (US)

Free
Krish Patel, Esprit Ma, Mei Wu, Kelley Myers, Cooper Bussberg, Jayne Galinsky, Zachary Frosch
Journal: Blood
Blood (2025) 146 (Supplement 1): 6180.
https://doi.org/10.1182/blood-2025-6180
Published: 2025
Journal Articles

Patients with relapsed/refractory (R/R) diffuse large B-cell lymphoma (DLBCL) preferred fixed-duration treatments with less frequent administrations in the era of novel bispecific antibodies (BsAbs)

Free
Zachary Frosch, Anthony Masaquel, David Fox, Carolina Reyes, Lourenia Cassoli, Dominic Lai, Kelley Myers, Cooper Bussberg, Krish Patel
Journal: Blood
Blood (2025) 146 (Supplement 1): 6179.
https://doi.org/10.1182/blood-2025-6179
Published: 2025
Journal Articles

Real-world outcomes of patients with aggressive B-cell lymphoma treated with epcoritamab or glofitamab

Available to Purchase
Clinical Trials & Observations
Taylor R. Brooks, Emily C. Zabor, Yohanna B. Bedelu, Xi Yang, Yasmin H. Karimi, Adrienne N. Nedved, Yucai Wang, Nikita Dave, Daniel J. Landsburg, Kelsey Baron, Boyu Hu, Daniel C. Trotier, Priyanka A. Pophali, Jordan Miller, Natalie Grover, Catherine Reinert, Ajay Major, Tenley Schwarz, Krish Patel, Kiarash Salafian, Emily Ayers, Suchitra Sundaram, Joshua D. Brody, Marshall McKenna, Yun Kyoung Ryu Tiger, Megan Sears-Smith, Nilanjan Ghosh, Chelsea Peterson, Cyrus Khan, Sean P. Bliven, Mayur Narkhede, Alyssa Gibson, Justin Kline, Javier Munoz, Rodolfo Garza-Morales, Carrie I. Ho, Stephen D. Smith, Alex Niu, Francisco Hernandez-Ilizaliturri, Fadzai Chinyengetere, Sandeep Dave, Nayef Abdel-Razeq, Muhamad Alhaj Moustafa, Paolo F. Caimi, Brian T. Hill
Journal: Blood
Blood (2025) 146 (18): 2177–2188.
https://doi.org/10.1182/blood.2025029117
Published: 2025
Includes: Supplemental data
Journal Articles

Brexucabtagene autoleucel for BTKi-naive relapsed/refractory mantle cell lymphoma: primary analysis of ZUMA-2 Cohort 3

Open Access
Clinical Trials & Observations
Tom van Meerten, Marie José Kersten, Gloria Iacoboni, Georg R. Hess, Pim G.N.J. Mutsaers, Alejandro Martin Martin Garcia-Sancho, Andre Goy, Eva Gine, Brian T. Hill, Wen-Kai Weng, Patrick M. Reagan, Krish Patel, Ahmed Galal, Charles Herbaux, Robin Sanderson, Edouard Forcade, Max S. Topp, Roch Houot, Dan Zheng, Wangshu Zhang, Justyna Kanska, Rhine R Shen, Rita Damico Khalid, Ioana Kloos, Martin Dreyling, Michael L Wang
Journal: Blood
Blood blood.2025029734.
https://doi.org/10.1182/blood.2025029734
Published: 2025
Includes: Supplemental data
Journal Articles

Genomic Determinants of Response and Resistance to Pirtobrutinib in Relapsed/Refractory Chronic Lymphocytic Leukemia

Open Access
Clinical Trials & Observations
Jennifer R. Brown, Bastien Nguyen, Sai Prasad Desikan, Helen Won, Shady I. Tantawy, Samuel C McNeely, Narasimha Marella, Hetal S Randeria, Lauren M Hanson, Andrew Parker, Salome Calado Botelho, Jennifer A. Woyach, Krish Patel, Constantine S Tam, Toby A. Eyre, Chan Y Cheah, Nirav N Shah, Paolo Ghia, Wojciech Jurczak, Minna Balbas, Binoj Chandrasekharan Nair, Paolo B. Abada, Chunxiao Wang, Denise Wang, Lindsey Elizabeth Roeker, Varsha Gandhi, William G. Wierda
Journal: Blood
Blood blood.2024027009.
https://doi.org/10.1182/blood.2024027009
Published: 2025
Includes: Supplemental data
Journal Articles

Acalabrutinib-obinutuzumab improves survival vs chemoimmunotherapy in treatment-naive CLL in the 6-year follow-up of ELEVATE-TN

Open Access
Clinical Trials & Observations
Jeff P. Sharman, Miklos Egyed, Wojciech Jurczak, Alan Skarbnik, Krish Patel, Ian W. Flinn, Manali Kamdar, Talha Munir, Renata Walewska, Marie Hughes, Laura Maria Fogliatto, Yair Herishanu, Versha Banerji, George Follows, Patricia Walker, Paolo Ghia, Ann Janssens, John C. Byrd, Emmanuelle Ferrant, Alessandra Ferrajoli, William G. Wierda, Catherine Wangui Wachira, Batul T. Suterwala, Paulo Miranda, Veerendra Munugalavadla, Chuan-Chuan Wun, Jennifer A. Woyach
Journal: Blood
Blood (2025) 146 (11): 1276–1285.
https://doi.org/10.1182/blood.2024024476
Published: 2025
Includes: Supplemental data
Journal Articles

Tolerability, Efficacy, Pharmacokinetics, and Pharmacodynamics of BMS-986353 (CC-97540), a CD19-Directed Chimeric Antigen Receptor (CAR) T Cell Therapy Manufactured Using a Next-Generation Process, for Severe, Refractory Autoimmune Diseases: Updated Data from Ongoing Phase 1, Multicenter, Open-Label Studies

Free
Fabian Mueller, Krish Patel, Ran Reshef, Mohamad Cherry, Richard Nash, Ernesto Ayala, Jingmei Hsu, Jacques Azzi, Peter Vandenberghe, Roch Houot, Bastian von Tresckow, Giuseppina Stifano, Ashley Koegel, Susana Falcon, Burhan Chaudhry, Lisa Kelly, Jerill Thorpe, Alyse Frisbee, Sam Charab, Sharmila Das, Thomas Ly, Ken Ogasawara, Paolo Caimi
Journal: Blood
Blood (2024) 144 (Supplement 1): 2088.
https://doi.org/10.1182/blood-2024-194525
Published: 2024
Journal Articles

Molecular and Clinical Determinants of CAR-T Therapy Response in DLBCL

Free
Devang Thakkar, Brian T. Hill, Rachel Kositsky, Shari Tian, Leonardo Biral, Veronica Russell, Tushar Dave, Cassandra L. Love, Caroline Roth, Matthew Stuart McKinney, Ahmed Galal, Jadee Neff, Agrima Mian, Ellen Kendall, Sarah L. Ondrejka, Matthew Chiaramonte, Govind Bhagat, Kenneth N. Ofori, Ran Reshef, Alexandra E. Kovach, Tarsheen Sethi, Emily F. Mason, Shakthi Bhaskar, Olalekan O. Oluwole, Chad McCall, Christopher Pallas, Nilanjan Ghosh, Robert Ferdman, George Chen, Francisco Hernandez-Ilizaliturri, Joanna Zurko, Ashley Cunningham, Nirav C Shah, Boyu Hu, Deborah M. Stephens, Monalisa Ghosh, Neil Bailey, Krish Patel, John M. Pagel, Kavya Kannamma Kannan, Eric D. Hsi, Rakhee Vaidya, Andrew Ip, Andre Goy, Swetha Kambhampati, Robert Ohgami, Charalambos Andreadis, Christian A Gordillo, Brianna Just, Jonathon B Cohen, Arielle Baim, Julie Barbello, Erika Cavallone, Veronika Bachanova, Maureen Laschen, Andinet Teferra, Frederique Lorcy, Sylvain Lamure, Guillaume Cartron, Valerie Dardalhon, Kikkeri N Naresh, Magdalena Czader, Anupama Reddy, Elizabeth Thacker, Clayton Parker, Lanie Happ, Sandeep Dave
Journal: Blood
Blood (2024) 144 (Supplement 1): 3409.
https://doi.org/10.1182/blood-2024-199758
Published: 2024
Journal Articles

Primary Analysis of ZUMA-2 Cohort 3: Brexucabtagene Autoleucel (Brexu-Cel) in Patients (Pts) with Relapsed/Refractory Mantle Cell Lymphoma (R/R MCL) Who Were Naive to Bruton Tyrosine Kinase Inhibitors (BTKi)

Free
Tom van Meerten, M.J. Kersten, Gloria Iacoboni, Georg Hess, Pim Mutsaers, Alejandro Martín García-Sancho, Andre Goy, Eva Gine, Brian T. Hill, Wen-Kai Weng, Martin Dreyling, Patrick M. Reagan, Krish Patel, Ahmed Galal, Charles Herbaux, Robin Sanderson, Dan Zheng, Justyna Kanska, Wangshu Zhang, Rita Damico Khalid, Ioana Kloos, Michael Wang
Journal: Blood
Blood (2024) 144 (Supplement 1): 748.
https://doi.org/10.1182/blood-2024-198021
Published: 2024