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Shady I. Tantawy
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Journal Articles

Genomic Determinants of Response and Resistance to Pirtobrutinib in Relapsed/Refractory Chronic Lymphocytic Leukemia

Open Access
Clinical Trials & Observations
Jennifer R. Brown, Bastien Nguyen, Sai Prasad Desikan, Helen Won, Shady I. Tantawy, Samuel C McNeely, Narasimha Marella, Hetal S Randeria, Lauren M Hanson, Andrew Parker, Salome Calado Botelho, Jennifer A. Woyach, Krish Patel, Constantine S Tam, Toby A. Eyre, Chan Y Cheah, Nirav N Shah, Paolo Ghia, Wojciech Jurczak, Minna Balbas, Binoj Chandrasekharan Nair, Paolo B. Abada, Chunxiao Wang, Denise Wang, Lindsey Elizabeth Roeker, Varsha Gandhi, William G. Wierda
Journal: Blood
Blood blood.2024027009.
https://doi.org/10.1182/blood.2024027009
Published: 2025
Includes: Supplemental data
Journal Articles

Impact of Docirbrutinib (AS-1763) Treatment in CLL: Preclinical Data and Early Clinical Biomarkers

Free
Natalia Timofeeva, Breana Herrera, Shady I. Tantawy, Hitomi Fujiwara, Lizbeth Loza, Mariko Hatakeyama, Tokiko Asami, Hiroshi Ohmoto, Kyoko Miyamoto, Yu Nishioka, Akinori Arimura, Masaaki Sawa, Nitin Jain, Varsha Gandhi
Journal: Blood
Blood (2024) 144 (Supplement 1): 1850.
https://doi.org/10.1182/blood-2024-210788
Published: 2024
Journal Articles

Characterization and Preclinical Evaluation of AS-1763, an Oral, Potent and Selective Noncovalent BTK Inhibitor, in Chronic Lymphocytic Leukemia

Free
Shady I. Tantawy, Natalia Timofeeva, Hitomi Fujiwara, Mariko Hatakeyama, Breana Herrera, Lizbeth Loza, Tokiko Asami, Hiroshi Ohmoto, Kyoko Miyamoto, Yu Nishioka, Akinori Arimura, Masaaki Sawa, Nitin Jain, Varsha Gandhi
Journal: Blood
Blood (2023) 142 (Supplement 1): 1453.
https://doi.org/10.1182/blood-2023-189659
Published: 2023
Journal Articles

Genomic Evolution and Resistance during Pirtobrutinib Therapy in Covalent BTK-Inhibitor (cBTKi) Pre-Treated Chronic Lymphocytic Leukemia Patients: Updated Analysis from the BRUIN Study

Free
Jennifer R. Brown, Sai Prasad Desikan, Bastien Nguyen, Helen Won, Shady I. Tantawy, Samuel McNeely, Narasimha Marella, Kevin Ebata, Jennifer A. Woyach, Krish Patel, Constantine S. Tam, Toby A. Eyre, Chan Y. Cheah, Nirav N. Shah, Paolo Ghia, Wojciech Jurczak, Minna Balbas, Binoj Nair, Paolo Abada, Chunxiao Wang, Ying (Denise) Wang, Lindsey E. Roeker, Varsha Gandhi, William G. Wierda
Journal: Blood
Blood (2023) 142 (Supplement 1): 326.
https://doi.org/10.1182/blood-2023-180143
Published: 2023
Journal Articles

Pharmacological Profiling of Cells from Patients with Chronic Lymphocytic Leukemia (CLL) Treated with Pirtobrutinib

Free
Shady I. Tantawy, Burcu Aslan, Lisa S Chen, Lakesla Iles, Philip A. Thompson, Nitin Jain, William G. Wierda, Varsha Gandhi
Journal: Blood
Blood (2022) 140 (Supplement 1): 501–502.
https://doi.org/10.1182/blood-2022-171119
Published: 2022