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Kylee Maclachlan
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Journal Articles

Genomic landscape of IgM-MGUS and patients with stable or progressive asymptomatic Waldenström macroglobulinemia

Available to Purchase
Tina Bagratuni, Ourania Theologi, Christos Vlachos, Ioannis Kollias, Kylee Maclachlan, Foteini Aktypi, Nefeli Mavrianou-Koutsoukou, Christine Liacos, Konstantina Taouxi, Alexandra Papadimou, Katerina Chrisostomidou, Maria Sakkou, Irene Solia, Foteini Theodorakakou, Gianmarco Favrin, Maria Gavriatopoulou, Evangelos Terpos, Marzia Varettoni, Zachary R. Hunter, Steven Treon, Francesco Maura, Meletios A. Dimopoulos, Efstathios Kastritis
Journal: Blood
Blood (2025) 146 (25): 3086–3097.
https://doi.org/10.1182/blood.2025030177
Published: 2025
Includes: Supplemental data
Journal Articles

Belantamab mafodotin, nirogacestat, and pomalidomide in patients with relapsed/refractory multiple myeloma

Free
Malin Hultcrantz, Hani Hassoun, Neha Korde, Carlyn Tan, Sergio Giralt, Alexander Lesokhin, Kylee Maclachlan, Dhwani Patel, Urvi Shah, Sridevi Rajeeve, Hamza Hashmi, Andriy Derkach, Ross Firestone, Linh Tran, Meredith Hyland, Kazunori Murata, Kevin Herrera, Karlo Perica, Saad Usmani, Sham Mailankody
Journal: Blood
Blood (2025) 146 (Supplement 1): 4060.
https://doi.org/10.1182/blood-2025-4060
Published: 2025
Journal Articles

Phase II trial of maintenance therapy with iberdomide after autologous hematopoietic cell transplant for patients with multiple myeloma previously treated with lenalidomide

Free
Natalia Tijaro Ovalle, Malin Hultcrantz, Khayla Leiva, Molly Hogan, Ambika Datta, Anjali Patel, Hamza Hashmi, Hani Hassoun, Neha Korde, Alexander Lesokhin, Kylee Maclachlan, Sham Mailankody, Sridevi Rajeeve, Urvi Shah, Carlyn Tan, Saad Usmani, David Chung, Heather Landau, Michael Scordo, Sergio Giralt, Gunjan Shah
Journal: Blood
Blood (2025) 146 (Supplement 1): 4048.
https://doi.org/10.1182/blood-2025-4048
Published: 2025
Journal Articles

Effectiveness of remote patient monitoring in enabling outpatient step-up dosing for bispecifics at a large academic cancer center in the USA

Free
Sridevi Rajeeve, Matt Wilkes, Nicole Zahradka, Maithili Deshpande, Alice Wang, Issam Hamadeh, Kelly Aliaga, Katie Jones, Kylee Maclachlan, Hamza Hashmi, Carlyn Tan, Malin Hultcrantz, Alexander Lesokhin, Hani Hassoun, Maximillian Merz, Francesco Maura, Parastoo Dahi, Michael Scordo, Heather Landau, Gunjan Shah, Sergio Giralt, Sham Mailankody, Felice Yang, Niodita Gupta-Werner, Tonya Le Blanc, Jessica Fowler, Shuchita Kaila, Saad Usmani, Neha Korde
Journal: Blood
Blood (2025) 146 (Supplement 1): 2751.
https://doi.org/10.1182/blood-2025-2751
Published: 2025
Journal Articles

Phylogenetic reconstruction reveals early divergence and late expansion of focal lesions in multiple myeloma

Free
Alexandra Poos, Lukas John, Kylee Maclachlan, Marc-Andrea Baertsch, Nina Prokoph, Juan-Jose Garces, Nina Hildenbrand, Christoph Rehnitz, Jan Frenking, Elias K. Mai, Philipp Reichert, Stefanie Huhn, Alexander Brobeil, Carsten Mueller-Tidow, Hartmut Goldschmidt, Saad Usmani, Sandra Sauer, Leo Rasche, Marc Raab, Francesco Maura, Niels Weinhold
Journal: Blood
Blood (2025) 146 (Supplement 1): 685.
https://doi.org/10.1182/blood-2025-685
Published: 2025
Journal Articles

Second primary malignancies in multiple myeloma: Incidence, survival and prognostic factors from a large single-center observational study

Free
Noriko Nishimura, Andriy Derkach, Kelly Barnett, Tala Shekarkhand, Issam Hamadeh, Heather Landau, Michael Scordo, Gunjan Shah, Roni Shouval, Ross Firestone, Sridevi Rajeeve, Francesco Maura, Hamza Hashmi, Maximillian Merz, Malin Hultcrantz, Neha Korde, Alexander Lesokhin, Sham Mailankody, Urvi Shah, Kylee Maclachlan, Carlyn Tan, Sergio Giralt, Saad Usmani, Hani Hassoun
Journal: Blood
Blood (2025) 146 (Supplement 1): 2213.
https://doi.org/10.1182/blood-2025-2213
Published: 2025
Journal Articles

Low dose tocilizumab for mitigation of cytokine release syndrome with bispecific antibodies in relapsed/refractory multiple myeloma

Free
Issam Hamadeh, Maximillian Merz, Andriy Derkach, Tala Shekarkhand, Alexander Lesokhin, Sham Mailankody, Malin Hultcrantz, Carlyn Tan, Hani Hassoun, Urvi Shah, Kylee Maclachlan, Sridevi Rajeeve, Hamza Hashmi, Francesco Maura, Ross Firestone, Alice Wang, Dhwani Patel, Michael Scordo, Gunjan Shah, Heather Landau, Sergio Giralt, Saad Usmani, Neha Korde
Journal: Blood
Blood (2025) 146 (Supplement 1): 2210.
https://doi.org/10.1182/blood-2025-2210
Published: 2025
Journal Articles

Functionally high-risk disease is associated with inferior outcomes after chimeric antigen receptor T-cell therapy for relapsed refractory multiple myeloma

Free
Tara Sebastian, Hamza Hashmi, Ross Firestone, Eric Jurgens, Sridevi Rajeeve, Tasmin Farzana, Maximilian Merz, Carlyn Tan, Kylee Maclachlan, Francesco Maura, Neha Korde, Hani Hassoun, Urvi Shah, Malin Hultcrantz, Heather Landau, Michael Scordo, Alexander Lesokhin, Andriy Derkach, David Nemirovsky, Sergio Giralt, Sham Mailankody, Saad Usmani
Journal: Blood
Blood (2025) 146 (Supplement 1): 2291.
https://doi.org/10.1182/blood-2025-2291
Published: 2025
Journal Articles

Lenalidomide-related diarrhea is associated with gut microbiota dysbiosis and disruption of the bile acid pool

Free
Kevin Miller, Teng Fei, Ruben Ramos, Ana Catarina Gradissimo De Oliveira, Jennifer Haber, Minsu Jaun, Francesca Castro, Andriy Derkach, Issam Hamadeh, Kylee Maclachlan, Malin Hultcrantz, Hani Hassoun, Sham Mailankody, Sridevi Rajeeve, Francesco Maura, Maximillian Merz, Hamza Hashmi, Ross Firestone, Eric Jurgens, Gunjan Shah, Michael Scordo, Heather Landau, Jonathan Peled, Sergio Giralt, Neha Korde, Saad Usmani, Urvi Shah, Alexander Lesokhin
Journal: Blood
Blood (2025) 146 (Supplement 1): 2233.
https://doi.org/10.1182/blood-2025-2233
Published: 2025
Journal Articles

On the cellular origins of multiple myeloma

Free
Dennis Lee, Patrick Blaney, Reva Shenwai, Sanghoon Lee, Di Zhang, Marc Braunstein, David Kaminetzky, Lisa Cervia, Kern Hast, Timothy Chu, Lara Winterkorn, Benjamin Diamond, Neha Korde, Alexander Lesokhin, Elizabeth Brown, Nicolas Robine, Kylee Maclachlan, Francesco Maura, Saad Usmani, Ola Landgren, Brian Walker, Faith Davies, Iryna Berezniuk, Oscar Lahoud, Christopher Park, Gareth Morgan
Journal: Blood
Blood (2025) 146 (Supplement 1): 5694.
https://doi.org/10.1182/blood-2025-5694
Published: 2025
Journal Articles

Whole genome sequencing of cell-free DNA for assessment of minimal residual disease in high-risk smoldering multiple myeloma

Free
Chrissy Baker, Elizabeth Hill, Dickran Kazandjian, Marios Papadimitriou, Michael Durante, Abhishek Pandey, Bachisio Ziccheddu, Tomas Jelinek, David Coffey, Brian Walker, Ryan Young, Kylee Maclachlan, Neha Korde, Nickoli Parkinson, Zoe Goldstein, Alexi Runnels, William Hooper, Nicolas Robine, Dan Avi Landau, Francesco Maura, Ola Landgren, Benjamin Diamond
Journal: Blood
Blood (2025) 146 (Supplement 1): 3920.
https://doi.org/10.1182/blood-2025-3920
Published: 2025
Journal Articles

The ribosome biogenesis inhibitor CX-5461 increases platelet count in humans and enhances murine megakaryopoiesis

Free
Vijay Bhoopalan, Amandeep Kaur, James Hearn, Kylee Maclachlan, Lixinyu Liu, Rita Ferreira, Sidra Ali, Yee-Lin Thong, Nadine Hein, Simone Brysland, Si Ming Man, Simon Harrison, Robert Andrews, Koji Eto, Philip Choi, Jiayu Wen, Ross Hannan, Elizabeth Gardiner
Journal: Blood
Blood (2025) 146 (Supplement 1): 3013.
https://doi.org/10.1182/blood-2025-3013
Published: 2025
Journal Articles

Daratumumab versus lenalidomide as maintenance therapy in newly diagnosed multiple myeloma – final results from a randomized investigator-initiated trial

Free
Sridevi Rajeeve, Andriy Derkach, Sean Devlin, Jeannen Santos, Anna Przemielewska, Tara Sood, Francesca Castro, Thomas Atkinson, Kylee Maclachlan, Hamza Hashmi, Carlyn Tan, Neha Korde, Malin Hultcrantz, Alexander Lesokhin, Hani Hassoun, Parastoo Dahi, Michael Scordo, David Chung, Heather Landau, Gunjan Shah, Ola Landgren, Sergio Giralt, Sham Mailankody, Saad Usmani, Urvi Shah
Journal: Blood
Blood (2025) 146 (Supplement 1): 2273.
https://doi.org/10.1182/blood-2025-2273
Published: 2025
Journal Articles

Factors associated with remote healthcare utilization in MM patients undergoing autologous stem cell transplantation

Free
Molly Benson, Anna Howard, Isabel Concepcion, Andriy Derkach, Gunjan Shah, Michael Scordo, Heather Landau, Sergio Giralt, Malin Hultcrantz, Carlyn Tan, Sham Mailankody, Hani Hassoun, Hamza Hashmi, Sridevi Rajeeve, Urvi Shah, Neha Korde, Kylee Maclachlan, Francesco Maura, Alexander Lesokhin, Miguel-Angel Perales, David Chung, Saad Usmani, Ross Firestone
Journal: Blood
Blood (2025) 146 (Supplement 1): 2632.
https://doi.org/10.1182/blood-2025-2632
Published: 2025
Journal Articles

Genomics define neoplastic transformation in multiple myeloma precursor conditions

Free
Francesco Maura, P. Leif Bergsagel, Bachisio Ziccheddu, Shaji Kumar, Kylee Maclachlan, Andriy Derkach, Juan-Jose Garces, Ross Firestone, Esteban Braggio, Yan Asmann, Michael Durante, Benjamin Diamond, Marios Papadimitriou, Malin Hultcrantz, Giancarlo Castellano, Alessio Marella, Akihiro Maeda, Marta Lionetti, Antonio Matera, Stefania Pioggia, Matteo Claudio Da Vià, Claudio de Magistris, Daniel Leongamornlert, Daniel Deavila, Praneeth Reddy Sudalagunta, Rafael Renatino Canevarolo, Erin Siegel, Phaedra Agius, Jamie Teer, Andrew McPherson, Yusuke Yamashita, Ariosto Siqueira Silva, Patrick Blaney, Rachid Baz, Krina Patel, Peter Campbell, Gareth Morgan, Rafael Fonseca, Ola Landgren, Robert Orlowski, Kenneth Shain, Niccolo Bolli, Saad Usmani, Vincent Rajkumar
Journal: Blood
Blood (2025) 146 (Supplement 1): 686.
https://doi.org/10.1182/blood-2025-686
Published: 2025
Journal Articles

The biological and clinical impact of deletions before and after large chromosomal gains in multiple myeloma

Free
Anthony M. Cirrincione, Alexandra M. Poos, Bachisio Ziccheddu, Marcella Kaddoura, Marc-Andrea Bärtsch, Kylee Maclachlan, Monika Chojnacka, Benjamin Diamond, Lukas John, Philipp Reichert, Stefanie Huhn, Patrick Blaney, Dylan Gagler, Karsten Rippe, Yanming Zhang, Ahmet Dogan, Alexander M. Lesokhin, Faith Davies, Hartmut Goldschmidt, Roland Fenk, Katja C. Weisel, Elias K. Mai, Neha Korde, Gareth J. Morgan, Saad Usmani, Ola Landgren, Marc S. Raab, Niels Weinhold, Francesco Maura
Journal: Blood
Blood (2024) 144 (7): 771–783.
https://doi.org/10.1182/blood.2024024299
Published: 2024
Includes: Supplemental data
Journal Articles

Tracking the evolution of therapy-related myeloid neoplasms using chemotherapy signatures

Free
Benjamin Diamond, Bachisio Ziccheddu, Kylee Maclachlan, Justin Taylor, Eileen Boyle, Juan Arango Ossa, Jacob Jahn, Maurizio Affer, Tulasigeri M. Totiger, David Coffey, Namrata Chandhok, Justin Watts, Luisa Cimmino, Sydney X. Lu, Niccolò Bolli, Kelly Bolton, Heather Landau, Jae H. Park, Karuna Ganesh, Andrew McPherson, Mikkael A. Sekeres, Alexander Lesokhin, David J. Chung, Yanming Zhang, Caleb Ho, Mikhail Roshal, Jeffrey Tyner, Stephen Nimer, Elli Papaemmanuil, Saad Usmani, Gareth Morgan, Ola Landgren, Francesco Maura
Journal: Blood
Blood (2023) 141 (19): 2359–2371.
https://doi.org/10.1182/blood.2022018244
Published: 2023
Includes: Supplemental data