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Journal Articles

Whole-genome analysis identifies novel drivers and high-risk double-hit events in relapsed/refractory myeloma

Naser Ansari-Pour, Mehmet Samur, Erin Flynt, Sarah Gooding, Fadi Towfic, Nicholas Stong, Maria Ortiz Estevez, Konstantinos Mavrommatis, Brian Walker, Gareth Morgan, Nikhil Munshi, Herve Avet-Loiseau, Anjan Thakurta
Journal: Blood
Blood (2023) 141 (6): 620–633.
https://doi.org/10.1182/blood.2022017010
Published: 2023
Includes: Supplemental data
Journal Articles

Multiomic Mapping of Copy Number and Structural Variation on Chromosome 1 (Chr1) Highlights Multiple Recurrent Disease Drivers

Patrick Blaney, Eileen M Boyle, Yubao Wang, Hussein Ghamlouch, Jinyoung Choi, Louis Williams, Stoeckle James, Ariel Siegel, Beatrice Razzo, Marc Braunstein, David Kaminetzky, Arnaldo A Arbini, Benedetto Bruno, Jill Corre, Lydia Montes, Daniel Auclair, Faith E. Davies, Aristotelis Tsirigos, Even H Rustad, Francesco Maura, Ola Landgren, Michael A Bauer, Brian Walker, Gareth Morgan
Journal: Blood
Blood (2021) 138 (Supplement 1): 721.
https://doi.org/10.1182/blood-2021-148439
Published: 2021
Journal Articles

Unifying the Definition of High-Risk in Multiple Myeloma

Ariel Siegel, Eileen M Boyle, Patrick Blaney, Yubao Wang, Hussein Ghamlouch, Jinyoung Choi, Jessica Caro, Louis Williams, Beatrice Razzo, Arnaldo A. Arbini, Marc Braunstein, David Kaminetzky, Daniel Auclair, Charlotte Pawlyn, David Cairns, Graham Jackson, Brian Walker, Benedetto Bruno, Gareth J. Morgan, Faith E. Davies
Journal: Blood
Blood (2021) 138 (Supplement 1): 2714.
https://doi.org/10.1182/blood-2021-148502
Published: 2021
Journal Articles

Whole-Genome Sequencing Reveals Evidence of Two Biologically and Clinically Distinct Entities: Progressive Versus Stable Myeloma Precursor Disease

Bénedith Oben, Guy Froyen, Kylee H Maclachlan, Binbin Zheng-Lin, MDMSc, Venkata Yellapantula, PhD, Federico Abascal, Daniel A. Leongamornlert, PhD, Andriy Derkach, PhD, Ellen Geerdens, Benjamin Diamond, MD, Ingrid Arijs, Brigitte Maes, Kimberly Vanhees, Malin Hultcrantz, MD PhD, Ahmet Dogan, MD PhD, Yanming Zhang, MD, Aneta Mikulasova, Brian Walker, PhD, Gareth Morgan, MDPhDFRCP, Peter J Campbell, Ola Landgren, MD PhD, Jean-Luc Rummens, Niccolo Bolli, MD PhD, Francesco Maura, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 47–48.
https://doi.org/10.1182/blood-2020-136403
Published: 2020
Journal Articles

Impact of Etiological Cytogenetic Abnormalities on Immunoparesis and Progression-Free and Overall Survival in Newly Diagnosed Multiple Myeloma

Jessica Caro, MD, David Cairns, MSc, PhD, Tom Menzies, Charlotte Pawlyn, BA,PhDMBBChir,MRCP,FRCPath, Eileen M Boyle, MD MSc, Gareth Morgan, MD PhD, Gordon Cook, MB ChB, PhD, Martin F. Kaiser, MD FRCP, FRCPath, Roger G Owen, MD, Walter M Gregory, PhD, Graham H Jackson, MD MA, MB BS, FRCP, FRCPath, Brian Walker, PhD, Jennifer LJ Heaney, PhD, Mark T Drayson, MB ChB, PhD FRCPath, Faith E. Davies
Journal: Blood
Blood (2020) 136 (Supplement 1): 6.
https://doi.org/10.1182/blood-2020-133516
Published: 2020
Journal Articles

Homozygous Deletions Can Be Used to Define a Cell Death Specific Gene Expression Signature Able to Predict Outcome in Myeloma

Nicholas J Dickens, DPhil, Brian Walker, PhD, Paola E Leone, PhD, Matthew W Jenner, Faith Davies, MD, Gareth J Morgan, MD, PhD
Journal: Blood
Blood (2008) 112 (11): 2725.
https://doi.org/10.1182/blood.V112.11.2725.2725
Published: 2008
Journal Articles

Bcr-Abl Positive Cells Display Increased Proteasome Activity and Greater Sensitivity to Proteasome Inhibition

Lisa Crawford, PhD, BSc, Philip Windrum, MD, MRCPath, Laura Magill, PhD, BSc, Junia V. Melo, MD, PhD, FRCPath, Lynn McCallum, PhD, BSc, MaryFrances McMullin, MD, Huib Ovaa, PhD, BSc, Brian Walker, PhD, BSc, Alexandra Irvine, PhD
Journal: Blood
Blood (2008) 112 (11): 3192.
https://doi.org/10.1182/blood.V112.11.3192.3192
Published: 2008
Journal Articles

siRNA Knockdown of MMSET Disrupts Cell Cycle and Induces Apoptosis in t(4;14) Myeloma.

Jose Brito, Brian Walker, Faith Davies, Julie Irving, Gareth J. Morgan
Journal: Blood
Blood (2007) 110 (11): 245.
https://doi.org/10.1182/blood.V110.11.245.245
Published: 2007
Journal Articles

Evaluation of the Specificity and Cytotoxicity of Three Proteasome Inhibitors.

Lisa J.A. Crawford, Huib Ovaa, Brian Walker, Dharminder Chauhan, Kenneth C. Anderson, Treen C.M. Morris, Alexandra E. Irvine
Journal: Blood
Blood (2005) 106 (11): 3366.
https://doi.org/10.1182/blood.V106.11.3366.3366
Published: 2005
Journal Articles

Streptokinase-induced platelet activation involves antistreptokinase antibodies and cleavage of protease-activated receptor-1

James P. McRedmond, Patrick Harriott, Brian Walker, Desmond J. Fitzgerald
Journal: Blood
Blood (2000) 95 (4): 1301–1308.
https://doi.org/10.1182/blood.V95.4.1301.004k24_1301_1308
Published: 2000