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Journal Articles

Comprehensive Genomic Characterization of Response and Resistance to Daratumumab-Based Quadruplet Induction in Newly Diagnosed Multiple Myeloma Patients

Kylee H Maclachlan, Carlyn Rose Tan, Tala Shekarkhand, Colin Rueda, Edith Serrano, David Nemirovsky, Andriy Derkach, Andrew McPherson, Benjamin Diamond, Bachisio Ziccheddu, Eileen Boyle, Hani Hassoun, Sham Mailankody, Urvi A Shah, Malin Hultcrantz, Sergio A. Giralt, David Chung, Heather Landau, Oscar Boutros Lahoud, Michael Scordo, Gunjan L. Shah, Yanming Zhang, Robert Cimera, Maria E. Arcila, Ahmet Dogan, Alexander Lesokhin, Gareth J. Morgan, Ola Landgren, Francesco Maura, Neha Korde, Saad Z Usmani
Journal: Blood
Blood (2023) 142 (Supplement 1): 3370.
https://doi.org/10.1182/blood-2023-187891
Published: 2023
Journal Articles

Targeted NGS Panel Guides Risk-Adapted Treatment Intention in Newly Diagnosed Myeloma Patients

Gaurav Agarwal, Mohammad Kazeroun, Mirian Salazar, Khrystal McBean, Lisa Ferguson, Jemma Larham, Jaimal Kothari, Naser Ansari-Pour, Sally Moore, Eileen Boyle, Udo Oppermann, Karthik Ramasamy, Angela Hamblin, Anjan Thakurta, Sarah Gooding
Journal: Blood
Blood (2023) 142 (Supplement 1): 644.
https://doi.org/10.1182/blood-2023-182734
Published: 2023
Journal Articles

The Cellular Impact, Immediate Targets and Mechanism of Action of NSD2 in t(4;14) Multiple Myeloma

Yubao Wang, Sanxiong Liu, Hussein Ghamlouch, Eileen Boyle, Faith E. Davies, Gareth J. Morgan
Journal: Blood
Blood (2023) 142 (Supplement 1): 1402.
https://doi.org/10.1182/blood-2023-189012
Published: 2023
Journal Articles

Single Cell Analysis of Bone Marrow Stromal Cells Shows That a Pro-Inflammatory and Stress Response Together with Polarized Differentiation of Stromal Elements Characterize the Bone Marrow Microenvironment during Multiple Myeloma Development

Hussein Ghamlouch, Dylan Gagler, Patrick Blaney, Eileen Boyle, Yubao Wang, Liming Hou, Ola Landgren, Francesco Maura, Aristotelis Tsirigos, Gareth J. Morgan, Faith E. Davies
Journal: Blood
Blood (2023) 142 (Supplement 1): 332.
https://doi.org/10.1182/blood-2023-182968
Published: 2023
Journal Articles

Tracking the evolution of therapy-related myeloid neoplasms using chemotherapy signatures

Benjamin Diamond, Bachisio Ziccheddu, Kylee Maclachlan, Justin Taylor, Eileen Boyle, Juan Arango Ossa, Jacob Jahn, Maurizio Affer, Tulasigeri M. Totiger, David Coffey, Namrata Chandhok, Justin Watts, Luisa Cimmino, Sydney X. Lu, Niccolò Bolli, Kelly Bolton, Heather Landau, Jae H. Park, Karuna Ganesh, Andrew McPherson, Mikkael A. Sekeres, Alexander Lesokhin, David J. Chung, Yanming Zhang, Caleb Ho, Mikhail Roshal, Jeffrey Tyner, Stephen Nimer, Elli Papaemmanuil, Saad Usmani, Gareth Morgan, Ola Landgren, Francesco Maura
Journal: Blood
Blood (2023) 141 (19): 2359–2371.
https://doi.org/10.1182/blood.2022018244
Published: 2023
Includes: Supplemental data
Journal Articles

Genomic Determinants of Resistance in Newly Diagnosed Multiple Myeloma Treated with Targeted-Immunotherapy

Francesco Maura, Eileen Boyle, David Coffey, Kylee H Maclachlan, Benjamin Diamond, Patrick Blaney, Dylan Gagler, Bachisio Ziccheddu, Hussein Ghamlouch, Yubao Wang, James E. Hoffman, Dickran Kazandjian, Hani Hassoun, Emily Guzman, Sham Mailankody, Urvi A Shah, Carlyn Tan, Malin Hultcrantz, Michael Scordo, Gunjan L. Shah, Heather Landau, David J. Chung, Sergio A. Giralt, Yanming Zhang, Ahmet Dogan, Alexander M Lesokhin, Dennis Verducci, Faith E. Davies, Saad Usmani, Neha Korde, Gareth J. Morgan, Ola Landgren
Journal: Blood
Blood (2022) 140 (Supplement 1): 1137–1139.
https://doi.org/10.1182/blood-2022-160308
Published: 2022
Journal Articles

Individualized Treatment-Adjusted Risk Stratification in Newly Diagnosed Multiple Myeloma

Francesco Maura, Arjun Raj Rajanna, Andriy Derkach, Bachisio Ziccheddu, Niels Weinhold, Kylee H Maclachlan, Benjamin Diamond, Faith E. Davies, Eileen Boyle, Brian A. Walker, Alexandra M Poos, Malin Hultcrantz, Ariosto Siqueira Silva, Oliver Hampton, Jamie Teer, Niccolò Bolli, Graham Jackson, Martin F. Kaiser, Charlotte Pawlyn, Gordon Cook, Dennis Verducci, Dickran Kazandjian, Frits van Rhee, Saad Usmani, Ken H. Shain, Marc S Raab, Gareth J. Morgan, Ola Landgren
Journal: Blood
Blood (2022) 140 (Supplement 1): 1561–1563.
https://doi.org/10.1182/blood-2022-160215
Published: 2022
Journal Articles

Impact of Rare Structural Variant Events in Newly Diagnosed Multiple Myeloma

Monika Chojnacka, Benjamin Diamond, Bachisio Ziccheddu, Even Rustad, Eileen Boyle, Kylee H Maclachlan, Patrick Blaney, Saad Usmani, Gareth J. Morgan, Ola Landgren, Francesco Maura
Journal: Blood
Blood (2022) 140 (Supplement 1): 1542–1543.
https://doi.org/10.1182/blood-2022-160311
Published: 2022
Journal Articles

A prospective phase 2 trial of daratumumab in patients with previously treated systemic light-chain amyloidosis

Clinical Trials & Observations
Murielle Roussel, Giampaolo Merlini, Sylvie Chevret, Bertrand Arnulf, Anne Marie Stoppa, Aurore Perrot, Giovanni Palladini, Lionel Karlin, Bruno Royer, Antoine Huart, Margaret Macro, Pierre Morel, Laurent Frenzel, Cyrille Touzeau, Eileen Boyle, Véronique Dorvaux, Fabien Le Bras, David Lavergne, Frank Bridoux, Arnaud Jaccard
Journal: Blood
Blood (2020) 135 (18): 1531–1540.
https://doi.org/10.1182/blood.2019004369
Published: 2020
Includes: Supplemental data
Journal Articles

Twice Weekly Induction with Ixazomib-Lenalidomide-Dexamethasone (IRd) Combination Followed By Extended IRD Consolidation and Lenalidomide Maintenance in Transplant Eligible Patients with Newly Diagnosed Multiple Myeloma (NDMM): A Phase 2 Study from the Intergroupe Francophone Du Myelome (IFM 2014-03)

Murielle Roussel, MD, Benjamin Hebraud, MD, Cyrille Hulin, MD, Xavier Leleu, MD PhD, Thierry Facon, MD, Eileen Boyle, MD PhD, Cyrille Touzeau, MD PhD, Brigitte Pegourie, MD, Aurore Perrot, MD PhD, Anne-Marie Stoppa, MD, Jean-Pierre Marolleau, MD PhD, Philippe Moreau, MD, Herve Avet-Loiseau, MD PhD, Laure Devlamynck, Valerie Lauwers-Cances, MD, Michel Attal, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3159.
https://doi.org/10.1182/blood-2019-123184
Published: 2019
Journal Articles

Primary Diffuse Large B-Cell CNS Lymphoma over 80 Years: An Analysis of 110 Patients from the French Oculo-Cerebral Lymphoma (LOC) Network

Alizee Maarek, MD, Delphine Maucort-Boulch, MD PhD, Caroline Houillier, MD, Olivier Chinot, MD PhD, Fontanet Bijou, MD, Luc Taillandier, MD PhD, Philippe Agape, MD, Roch Houot, MD PhD, Eileen Boyle, MD, Cecile Molucon-Chabrot, MD PhD, Philippe Rey, MD, Sylvain Choquet, MD, Jerome Tamburini Bonnefoy, MD PhD, Arnaud Jaccard, MD PhD, Guido Ahle, MD, Michel Fabbro, MD, Anne-Claire Gac, MD, Jean-Come Meniane, MD, Marie Francoise Le Coz, MD, Emmanuel Gyan, MD PhD, Khe Hoang-Xuan, MD PhD, Carole Soussain, MD PhD, Herv Ghesquieres
Journal: Blood
Blood (2018) 132 (Supplement 1): 4206.
https://doi.org/10.1182/blood-2018-99-117331
Published: 2018
Journal Articles

The Mutational Landscape of Primary Plasma Cell Leukemia

Carolina D. Schinke, MD, Cody Ashby, PhD, Yan Wang, Ruslana G. Tytarenko, MS, Eileen Boyle, Christopher Wardell, PhD, Pingping Qu, Sharmilan Thanendrarajan, MD, Sandra Susanibar, MD, Naveen Yarlagadda, MD, Maliha Khan, Meera Mohan, MD, Maurizio Zangari, MD, Frits van Rhee, MD PhD, Faith E. Davies, MD, Bart Barlogie, MD PhD, Gareth Morgan, MD, Brian A Walker, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 114.
https://doi.org/10.1182/blood-2018-99-116758
Published: 2018
Journal Articles

Long-Term Follow-up Identifies Double Hit and Key Mutations As Impacting Progression Free and Overall Survival in Multiple Myeloma

Cody Ashby, PhD, Eileen Boyle, Ruslana G. Tytarenko, MS, Hongwei Wang, MS, Adam Rosenthal, MS, Purvi Patel, Yan Wang, Shayu Deshpande, Maria Ortiz, Erin Flynt, Antje Hoering, PhD, Sharmilan Thanendrarajan, MD, Carolina D. Schinke, MD, Maurizio Zangari, MD, Frits van Rhee, MD PhD, Bart Barlogie, MD PhD, Anjan Thakurta, PhD, Gareth Morgan, MD, Brian A Walker, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 110.
https://doi.org/10.1182/blood-2018-99-113045
Published: 2018
Journal Articles

Final analysis of survival outcomes in the phase 3 FIRST trial of up-front treatment for multiple myeloma

Clinical Trials & Observations
Thierry Facon, Meletios A. Dimopoulos, Angela Dispenzieri, John V. Catalano, Andrew Belch, Michele Cavo, Antonello Pinto, Katja Weisel, Heinz Ludwig, Nizar J. Bahlis, Anne Banos, Mourad Tiab, Michel Delforge, Jamie D. Cavenagh, Catarina Geraldes, Je-Jung Lee, Christine Chen, Albert Oriol, Javier De La Rubia, Darrell White, Daniel Binder, Jin Lu, Kenneth C. Anderson, Philippe Moreau, Michel Attal, Aurore Perrot, Bertrand Arnulf, Lugui Qiu, Murielle Roussel, Eileen Boyle, Salomon Manier, Mohamad Mohty, Herve Avet-Loiseau, Xavier Leleu, Annette Ervin-Haynes, Guang Chen, Vanessa Houck, Lotfi Benboubker, Cyrille Hulin
Journal: Blood
Blood (2018) 131 (3): 301–310.
https://doi.org/10.1182/blood-2017-07-795047
Published: 2018
Includes: Supplemental data
Journal Articles

A Prospective Phase II of Daratumumab in Previously-Treated Systemic Light-Chain (AL) Amyloidosis

Murielle Roussel, MD, Anne-Marie Stoppa, MD, Aurore Perrot, MD, Lionel Karlin, MD, Bertrand Arnulf, MD PhD, Margaret Macro, MD, Antoine Huart, MD, Laurent Frenzel, MD PhD, Pierre Morel, MD, Eileen Boyle, MD, Veronique Dorvaux, MD, Giampaolo Merlini, MD, Giovanni Palladini, MDPhD, David Lavergne, PhD, Frank Bridoux, MD PhD, Arnaud Jaccard
Journal: Blood
Blood (2017) 130 (Supplement 1): 508.
https://doi.org/10.1182/blood.V130.Suppl_1.508.508
Published: 2017
Journal Articles

Efficacy and tolerability of nivolumab after allogeneic transplantation for relapsed Hodgkin lymphoma

Clinical Trials & Observations
Charles Herbaux, Jordan Gauthier, Pauline Brice, Elodie Drumez, Loic Ysebaert, Hélène Doyen, Luc Fornecker, Krimo Bouabdallah, Guillaume Manson, Hervé Ghesquières, Reza Tabrizi, Eric Hermet, Julien Lazarovici, Anne Thiebaut-Bertrand, Adrien Chauchet, Hélène Demarquette, Eileen Boyle, Roch Houot, Ibrahim Yakoub-Agha, Franck Morschhauser
Journal: Blood
Blood (2017) 129 (18): 2471–2478.
https://doi.org/10.1182/blood-2016-11-749556
Published: 2017
Journal Articles

Serum free light chains, not urine specimens, should be used to evaluate response in light-chain multiple myeloma

CME
Thomas Dejoie, Jill Corre, Helene Caillon, Cyrille Hulin, Aurore Perrot, Denis Caillot, Eileen Boyle, Marie-Lorraine Chretien, Jean Fontan, Karim Belhadj, Sabine Brechignac, Olivier Decaux, Laurent Voillat, Philippe Rodon, Olivier Fitoussi, Carla Araujo, Lotfi Benboubker, Charlotte Fontan, Mourad Tiab, Pascal Godmer, Odile Luycx, Olivier Allangba, Jean-Michel Pignon, Jean-Gabriel Fuzibet, Laurence Legros, Anne Marie Stoppa, Mamoun Dib, Brigitte Pegourie, Frederique Orsini-Piocelle, Lionel Karlin, Bertrand Arnulf, Murielle Roussel, Laurent Garderet, Mohamad Mohty, Nathalie Meuleman, Chantal Doyen, Pascal Lenain, Margaret Macro, Xavier Leleu, Thierry Facon, Philippe Moreau, Michel Attal, Herve Avet-Loiseau
Journal: Blood
Blood (2016) 128 (25): 2941–2948.
https://doi.org/10.1182/blood-2016-07-726778
Published: 2016
Journal Articles

Ibrutinib Monotherapy in Relapse or Refractory Primary CNS Lymphoma (PCNSL) and Primary Vitreo-Retinal Lymphoma (PVRL). Result of the Interim Analysis of the iLOC Phase II Study from the Lysa and the French LOC Network

Sylvain Choquet, MD, Caroline Houillier, MD, Fontanet Bijou, MD, Roch Houot, MD PhD, Eileen Boyle, MD, Remy Gressin, MD, Emmanuelle Nicolas-Virelizier, MD, Maryline Barrie, MD, Cecile Molucon-Chabrot, MD, Marie Blonski, MD, Abderrazak El Yamani, MD, Marie-Laure LeLez, MD, Aline Clavert, MD, Solène Coisy, MD, Marjan Ertault de la Bretonnière, MD, Valérie Touitou, MD PhD, Nathalie Cassoux, MD PhD, Sami Boussetta, Florence Broussais, MD, Benedicte Gelas-Dore, Noélie Barzic, Herve Ghesquieres, MD PhD, Khê Hoang-Xuan, MD PhD, Carole Soussain, MD PhD
Journal: Blood
Blood (2016) 128 (22): 784.
https://doi.org/10.1182/blood.V128.22.784.784
Published: 2016
Journal Articles

Can Assessment of Patient Monoclonal Immunoglobulins By Heavy/Light Analysis be Used to Assign Patient Responses Analogous to IMWG Response Criteria?

Eileen Boyle, Guillemette Fouquet, Julie Lejeune, Salomon Manier, MD, Lucile Musset, Claire Bories, Remy Dulery, MD, Stéphanie Guidez, Sarah Bonnet, Brigitte Onraed, Jean-Luc Faucompre, Sabine Tricot, Stephanie Poulain, Veronique Leblond, MD PhD, Kym Snell, Xavier Leleu, MD
Journal: Blood
Blood (2015) 126 (23): 3042.
https://doi.org/10.1182/blood.V126.23.3042.3042
Published: 2015
Journal Articles

Impact of Anti-CD20 Antibodies on the Incidence of Secondary Cancers in Patients Treated for Chronic Lymphocytic Leukemia

Stéphanie Guidez, Hélène Demarquette, Morgane Nudel, Charline Le Grand, Eileen Boyle, Charles Herbaux, MD, Thierry Facon, Bruno Cazin, MD, Franck Morschhauser, MD
Journal: Blood
Blood (2015) 126 (23): 5291.
https://doi.org/10.1182/blood.V126.23.5291.5291
Published: 2015