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Journal Articles

Real-world experience with first-line regimens in transplant-ineligible patients with multiple myeloma

Free
Danyal Ladha, Donna Reece, Guido Lancman, Arleigh McCurdy, Engin Gul, Smriti Sharma, Jiandong Su, Martha Louzada, Michael Chu, Alissa Visram, Darrell White, Julie Stakiw, Muhammad Aslam, Michael Sebag, Rami Kotb, Victor Jimenez-Zepeda, Eve St-Hilaire, Anthony Reiman, Kevin Song, Christopher Venner, Rayan Kaedbey, Debra Bergstrom, Jesse Shustik, Ashley Freeman, Philip Kuruvilla, richard Leblanc
Journal: Blood
Blood (2025) 146 (Supplement 1): 2798.
https://doi.org/10.1182/blood-2025-2798
Published: 2025
Journal Articles

Real-world outcomes of teclistamab for multiple myeloma in Canada: Multi-institutional report from the Canadian myeloma research group (CMRG) database

Free
Guido Lancman, Donna Reece, Arleigh McCurdy, Engin Gul, Smriti Sharma, Jiandong Su, Kevin Song, Michael Chu, Martha Louzada, Alissa Visram, Darrell White, Rayan Kaedbey, Jesse Shustik, Julie Stakiw, Michael Sebag, Rami Kotb, Victor Jimenez-Zepeda, Anthony Reiman, Christopher Venner, Muhammad Aslam, Debra Bergstrom, Ashley Freeman, Eve St-Hilaire, Philip Kuruvilla, richard Leblanc
Journal: Blood
Blood (2025) 146 (Supplement 1): 7596.
https://doi.org/10.1182/blood-2025-7596
Published: 2025
Journal Articles

Efficacy and Safety of Selinexor, Pomalidomide, and Dexamethasone (SPd) for Treatment of Patients with Relapsed or Refractory Multiple Myeloma (RRMM)

Free
Muhamed Baljevic, Nizar J. Bahlis, Rami Kotb, Gary J. Schiller, Brea Lipe, Sumit Madan, Heather J. Sutherland, Suzanne Lentzsch, Natalie Callander, Noa Biran, Dane Van Domelen, Tomer Mark, Darrell White
Journal: Blood
Blood (2024) 144 (Supplement 1): 1996.
https://doi.org/10.1182/blood-2024-208086
Published: 2024
Journal Articles

Identification of Novel Protein Biomarkers in Bone Marrow Interstitial Fluid Links Coagulation Cascade Proteins to Survival Outcomes in Multiple Myeloma

Free
Samuel Cutler, Amy Trottier, Daniel Gaston, Nicholas Allen Forward, Darrell White, Alfredo H. De La Torre, Manal Elnenaei
Journal: Blood
Blood (2024) 144 (Supplement 1): 1876.
https://doi.org/10.1182/blood-2024-193994
Published: 2024
Journal Articles

Mezigdomide (MEZI) Plus Dexamethasone (DEX) and Bortezomib (BORT) or Carfilzomib (CFZ) in Patients (pts) with Relapsed/Refractory Multiple Myeloma (RRMM): Updated Results from the CC-92480-MM-002 Trial

Free
Irwindeep Sandhu, Paul G. Richardson, Albert Oriol, Darrell White, Richard Leblanc, Noopur Raje, Enrique M. Ocio, Aurore Perrot, Thierry Facon, Cesar Rodriguez, Ralph Wäsch, Meletios A. Dimopoulos, Tracy T. Chow, Allison Gaudy, Jing Gong, Zehua Zhou, Tiziana Civardi, Joseph T. Hadala, Yue Zhu, Jessica Katz, Marc S. Raab
Journal: Blood
Blood (2024) 144 (Supplement 1): 1025.
https://doi.org/10.1182/blood-2024-198408
Published: 2024
Journal Articles

Final Results of the Canadian Myeloma Research Group Trial of Cybord Induction, Double-Alkylator Conditioning with High-Dose Intravenous Busulfan + Melphalan, ASCT and Continuous Lenalidomide Maintenance for Patients with Newly Diagnosed Multiple Myeloma (CMRG-001)

Free
Donna E Reece, Giovanni Piza Rodriguez, Mariela A Pantoja, Eshetu G Atenafu, Darrell White, Irwindeep Sandhu, Julie Stakiw, Michael Sebag, Terrance Comeau, Kevin Song, Jean Roy, Martha L Louzada, Arleigh McCurdy, Vishal Kukreti, Suzanne Trudel, Anca Prica, Rodger E Tiedemann, Christine I Chen
Journal: Blood
Blood (2024) 144 (Supplement 1): 3376.
https://doi.org/10.1182/blood-2024-206247
Published: 2024
Journal Articles

Cell-Free DNA Whole Genome Sequencing for Non-Invasive MRD Detection in Multiple Myeloma

Free
Dor D. Abelman, Jenna Eagles, Aimee Wong, Saumil Shah, Stephanie Pedersen, Sarah Bridges, Cecilia Bonolo De Campos, Darrell White, Irwindeep Sandhu, Kevin Song, Zac McDonald, Abir Khaled, Liqiang Yang, Alli Murugesan, Anthony Reiman, Suzanne Trudel, Trevor J. Pugh
Journal: Blood
Blood (2024) 144 (Supplement 1): 3338.
https://doi.org/10.1182/blood-2024-208740
Published: 2024
Journal Articles

Mezigdomide (MEZI) Plus Dexamethasone (DEX) and Daratumumab (DARA) or Elotuzumab (ELO) in Patients (pts) with Relapsed/Refractory Multiple Myeloma (RRMM): Results from the CC-92480-MM-002 Trial

Free
Paul G. Richardson, Irwindeep Sandhu, Craig C. Hofmeister, Robert Z. Orlowski, Darrell White, Angelo Belotti, Charlotte Toftmann Hansen, Noopur S. Raje, Tracy T. Chow, Zehua Zhou, Tiziana Civardi, Phillip Koo, Yue Zhu, Jessica Katz, Albert Oriol
Journal: Blood
Blood (2023) 142 (Supplement 1): 1013.
https://doi.org/10.1182/blood-2023-174443
Published: 2023
Journal Articles

Preclinical and Translational Biomarker Analyses to Inform Clinical Development of Mezigdomide (CC-92480) in Combination with Dexamethasone and Daratumumab in Multiple Myeloma

Free
Tracy T. Chow, Michael Amatangelo, Peilin Ma, Chad C. Bjorklund, Krista Wollerman, Tiziana Civardi, Phillip Koo, Yue Zhu, Paulo Maciag, Jessica Katz, Aparna Raval, Albert Oriol, Robert Z. Orlowski, Darrell White, Paul G. Richardson, Anita K. Gandhi
Journal: Blood
Blood (2023) 142 (Supplement 1): 3318.
https://doi.org/10.1182/blood-2023-178881
Published: 2023
Journal Articles

Second Line Treatment and Outcomes of Patients with Multiple Myeloma: A Real World Multi-Institutional Report from the Canadian Myeloma Research Group (CMRG) Database

Free
Arleigh McCurdy, Engin Gul, Donna Reece, Christopher P. Venner, Darrell White, Jiandong Su, Michael P. Chu, Victor H. Jimenez-Zepeda, Kevin Song, Hira Mian, Michael Sebag, Debra Bergstrom, Julie Stakiw, Anthony Reiman, Rami Kotb, Muhammad Aslam, Rayan Kaedbey, Martha L Louzada, Richard LeBlanc
Journal: Blood
Blood (2023) 142 (Supplement 1): 3364.
https://doi.org/10.1182/blood-2023-181138
Published: 2023
Journal Articles

Prevention of Ocular Toxicity Using Protective Contact Lenses in Multiple Myeloma Patients Receiving Belantamab Mafodotin, Pomalidomide and Dexamethasone: A Sub-Study of the Cmrg-007 Trial

Free
Martha L Louzada, Donna E. Reece, Arleigh McCurdy, Rami Kotb, Ibraheem Othman, Hira Mian, Toni Lin, Michael P Chu, Darrell White, Stephen Parkin, Engin Gul, Aniba Khan, Suzanne Trudel
Journal: Blood
Blood (2023) 142 (Supplement 1): 4756.
https://doi.org/10.1182/blood-2023-174993
Published: 2023
Journal Articles

Efficacy and Tolerance of Isatuximab, Cyclophosphamide, Bortezomib, and Dexamethasone (Isa-CBD) Induction Chemotherapy in Newly Diagnosed, Transplant Eligible Multiple Myeloma: Report of the Phase 2 Multi-Centre, Open Label Canadian Myeloma Research Group (CMRG)-008 Prospective Clinical Trial

Free
Rami Kotb, Darrell White, Sita Bhella, Arleigh McCurdy, Irwindeep Sandhu, Hira Mian, Julie Stakiw, Ibraheem Othman, Jiandong Su, Aniba Khan, Engin Gul, Donna Reece
Journal: Blood
Blood (2023) 142 (Supplement 1): 4751.
https://doi.org/10.1182/blood-2023-190168
Published: 2023
Journal Articles

Disease Characteristics and Outcomes of 504 Young Patients Diagnosed with Multiple Myeloma Treated with Modern Therapies in Canada

Free
Mégane Tanguay, Jean Roy, Jiandong Su, Engin Gul, Donna Reece, Christopher P. Venner, Darrell White, Michael P. Chu, Victor H. Jimenez-Zepeda, Kevin Song, Arleigh McCurdy, Hira Mian, Michael Sebag, Debra Bergstrom, Julie Stakiw, Anthony Reiman, Rami Kotb, Muhammad Aslam, Rayan Kaedbey, Martha L Louzada, Richard LeBlanc
Journal: Blood
Blood (2023) 142 (Supplement 1): 1954.
https://doi.org/10.1182/blood-2023-174338
Published: 2023
Journal Articles

Real World Data on Outcomes of Anti-CD38 Antibody Refractory, Including Triple Class Refractory, Patients with Multiple Myeloma: A Multi-Institutional Report from the Canadian Myeloma Research Group (CMRG) Database

Free
Alissa Visram, Alfredo De La Torre, Darrell White, Moustafa Kardjadj, Esther Masih-Khan, Michael P. Chu, Victor H Jimenez-Zepeda, Arleigh McCurdy, Richard Leblanc, Kevin Song, Hira S Mian, Martha L Louzada, Michael Sebag, Debra Bergstrom, Julie Stakiw, Anthony Reiman, Rami Kotb, Muhammad Aslam, Christopher P. Venner, Rayan Kaedbey, Engin Gul, Donna E. Reece
Journal: Blood
Blood (2022) 140 (Supplement 1): 4287–4289.
https://doi.org/10.1182/blood-2022-168843
Published: 2022
Journal Articles

Real-World Results of Autologous Stem Cell Transplantation in Newly Diagnosed Patients with Multiple Myeloma: A Multi-Institutional Report from the Canadian Myeloma Research Group (CMRG) Database

Free
Julie Cote, Richard Leblanc, Michael P. Chu, Arleigh McCurdy, Esther Masih-Khan, Moustafa Kardjadj, Victor H Jimenez-Zepeda, Kevin Song, Martha L Louzada, Hira S Mian, Darrell White, Michael Sebag, Anthony Reiman, Julie Stakiw, Rami Kotb, Debra Bergstrom, Muhammad Aslam, Rayan Kaedbey, Christopher P. Venner, Engin Gul, Donna E. Reece
Journal: Blood
Blood (2022) 140 (Supplement 1): 289–291.
https://doi.org/10.1182/blood-2022-158219
Published: 2022
Journal Articles

Elranatamab in Combination with Daratumumab for Patients (pts) with Relapsed/Refractory Multiple Myeloma (RRMM): Results from the Phase 3 Magnetismm-5 Study Safety Lead-in Cohort

Free
Sebastian Grosicki, Ulf-Henrik Mellqvist, Łukasz Pruchniewski, Jacob Crafoord, Suzanne Trudel, Chang-Ki Min, Darrell White, Adrian Alegre, Markus Hansson, Takashi Ikeda, Kazutaka Sunami, Eric Leip, Arthur Kudla, Gregory Finn, Youngil Koh
Journal: Blood
Blood (2022) 140 (Supplement 1): 4407–4408.
https://doi.org/10.1182/blood-2022-162738
Published: 2022
Journal Articles

Iberdomide (IBER) in Combination with Dexamethasone (DEX) in Relapsed/Refractory Multiple Myeloma (RRMM): Results from the Anti-B-Cell Maturation Antigen (BCMA)-Exposed Cohort of the CC-220-MM-001 Trial

Free
Sagar Lonial, Al-Ola Abdallah, Faiz Anwer, Ashraf Z. Badros, Manisha Bhutani, Abdullah Khan, Brea Lipe, Albert Oriol, Darrell White, Michael Amatangelo, Kexin Jin, Mark Masin, Vi Nguyen, Alpesh Amin, Paulo Maciag, Niels WCJ Van De Donk
Journal: Blood
Blood (2022) 140 (Supplement 1): 4398–4400.
https://doi.org/10.1182/blood-2022-158180
Published: 2022
Journal Articles

Selinexor-Based Regimens in Patients with Multiple Myeloma after Prior Anti-B-Cell Maturation Antigen Treatment

Free
Muhamed Baljevic, Cristina Gasparetto, Gary J. Schiller, Sascha A. Tuchman, Natalie S. Callander, Suzanne Lentzsch, Jorge Monge, Rami Kotb, Nizar J. Bahlis, Darrell White, Christine I. Chen, Heather J. Sutherland, Sumit Madan, Richard Leblanc, Michael Sebag, Christopher P. Venner, William I. Bensinger, Noa Biran, Andrew DeCastro, Dane R. Van Domelen, Ohad S. Bentur, Chris Zhang, Jatin J. Shah, Sharon Shacham, Michael G. Kauffman, Brea Lipe
Journal: Blood
Blood (2021) 138 (Supplement 1): 2751.
https://doi.org/10.1182/blood-2021-150998
Published: 2021
Journal Articles

CC-92480, a Potent, Novel Cereblon E3 Ligase Modulator (CELMoD) Agent, in Combination with Dexamethasone (DEX) and Bortezomib (BORT) in Patients (pts) with Relapsed/Refractory Multiple Myeloma (RRMM): Preliminary Results from the Phase 1/2 Study CC-92480-MM-002

Free
Paul G. Richardson, Enrique Ocio, Noopur S. Raje, Tara Gregory, Darrell White, Albert Oriol, Irwindeep Sandhu, Marc-Steffen Raab, Richard LeBlanc, Cesar Rodriguez, Suzanne Trudel, Ralph Wäsch, Aurore Perrot, Nizar J. Bahlis, Zehua Zhou, Manisha Lamba, Michael Amatangelo, Tiziana Civardi, Jessica Katz, Paulo Maciag, Teresa Peluso, Meletios A. Dimopoulos
Journal: Blood
Blood (2021) 138 (Supplement 1): 2731.
https://doi.org/10.1182/blood-2021-147812
Published: 2021
Journal Articles

Late vs Early Response and Depth of Response Are Associated with Improved Outcomes in Newly Diagnosed Multiple Myeloma (NDMM) Patients (pts) Treated with Ixazomib-Lenalidomide-Dexamethasone (IRd) or Placebo-Lenalidomide-Dexamethasone (pbo-Rd) in the Phase 3 TOURMALINE-MM2 Trial

Free
Paul G. Richardson, Thierry Facon, Christopher P. Venner, Nizar J. Bahlis, Fritz Offner, Darrell White, Lionel Karlin, Lotfi Benboubker, Sophie Rigaudeau, Eric Voog, Sung-Soo Yoon, Kenshi Suzuki, Hirohiko Shibayama, Xiaoquan Zhang, Arun Kumar, Philip Twumasi-Ankrah, Richard Labotka, Robert M. Rifkin, Sagar Lonial, Shaji Kumar, S. Vincent Rajkumar, Philippe Moreau
Journal: Blood
Blood (2021) 138 (Supplement 1): 2733.
https://doi.org/10.1182/blood-2021-148481
Published: 2021