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Journal Articles

Ending the undetermined significance of monoclonal gammopathies (MGUS): First results of the nomoremgus study

Free
Marta Lasa, Esperanza Martin-Sanchez, Aintzane Zabaleta, Diego Alignani, Carmen Gonzalez, Noemi Puig, Elena Alejo, Jorge Labrador, Maria Casanova Espinosa, Laura Rosiñol Dachs, Sebastián Garzón, Enrique Ocio, Albert Pérez-Montaña, Irene Romera, Carmen Couto, Sunil Lakhwani, Felipe Prosper, Adrian Alegre, Elena Cabezudo, Itziar Carro, Cristina Motlló, Montserrat Cortes, Isabel Maria Garcia Cabrera, Marta Romera, Javier de la Rubia, Andrea Manubens, Alexia Suarez Cabrera, Fernando Escalante Barrigón, Carlos Aguilar-Franco, Raquel Del Campo, Maria Esther Clavero Sanchez, Joaquin Martinez-Lopez, Valentin Cabanas Perianes, María-Jesús Blanchard, Ana Lopez-Guia, Diana Sanchez Arguello, Albert Oriol, Marta Reinoso -Segura, María Lourdes Amador Barciela, Celina Benavente Cuesta, Jose Maria Arguiñano PEREZ, Beatriz Ordoñez, Francisco Taboada, Joan Batista Blade Creixenti, María-Victoria Mateos, Juan-Jose Lahuerta Palacios, Jesus San-Miguel, Bruno Paiva
Journal: Blood
Blood (2025) 146 (Supplement 1): 578.
https://doi.org/10.1182/blood-2025-578
Published: 2025
Journal Articles

Circulating tumor cells (CTCs) for dynamic risk assessment of patients (Pts) with smoldering multiple myeloma (SMM)

Free
Esperanza Martin-Sanchez, Evangelos Terpos, Niels Weinhold, Albert Pérez-Montaña, Enrique Ocio, Elena Cabezudo, Joan Bargay, Artur Paiva, Rosalinda Termini, Hector Gracia, Cody Clayhold, David Žihala, Tomas Jelinek, Roman Hajek, Marc Raab, Elias K. Mai, Anna Luise Grab, Joaquin Martinez-Lopez, Irene Romera, Fernando Solano, Ianire Etxeguren, Rebeca Iglesias, Felipe de Arriba, Antonio Garcia, Heinz Ludwig, Albert Oriol, Maria Casanova Espinosa, Felipe Prosper, Aldo Roccaro, Marco Chiarini, Antonio Sacco, Adrian Alegre, Valentin Cabanas Perianes, Maialen Sirvent, Jill Corre, Francois Vergez, Herve Avet-Loiseau, María-Victoria Mateos, Noemi Puig, Jesus San-Miguel, Bruno Paiva
Journal: Blood
Blood (2025) 146 (Supplement 1): 493.
https://doi.org/10.1182/blood-2025-493
Published: 2025
Journal Articles

Head-to-head longitudinal comparison of two mass spectrometry-based methods for monitoring monoclonal proteins in multiple myeloma: Analytical and clinical insights from the GEM-CESAR trial

Free
Noemi Puig, Matthew Nichols, Cristina Agullo, Sergio Castro, Joaquin Martinez-Lopez, Marta Sonia Gonzalez Perez, Albert Oriol, Rafael Rios Tamayo, Laura Rosiñol, Joan Bargay, Ana Pilar Gonzalez, Chai Phua, Adrian Alegre, María Belen Iñigo, Javier de la Rubia, Anabel Teruel, Miguel Paricio, Felipe de Arriba, Sunil Lakhwani, Javier Lopez Jimenez, Marta Reinoso -Segura, Joan Batista Blade Creixenti, Juan-Jose Lahuerta Palacios, María Teresa Cedena, Bruno Paiva, Jesus San-Miguel, Martha Louzada, María-Victoria Mateos
Journal: Blood
Blood (2025) 146 (Supplement 1): 2238.
https://doi.org/10.1182/blood-2025-2238
Published: 2025
Journal Articles

Early rescue intervention with daratumumab, pomalidomide and dexamethasone (DPd) in high-risk smoldering myeloma (HR-SMM) patients included in the GEM-CESAR treated with carfilzomib, lenalidomide and dexamethasone (KRd)- autologous stem cell transplantation (ASCT)-krd-rd

Free
María-Victoria Mateos, Joaquin Martinez-Lopez, Verónica González-Calle, Marta Sonia Gonzalez Perez, Albert Oriol, Javier Lopez Jimenez, Marta Reinoso -Segura, Rafael Rios Tamayo, Paula Rodriguez-Otero, Laura Rosiñol Dachs, Javier de la Rubia, Felipe de Arriba, Sunil Lakhwani, Joan Bargay, Ana Pilar Gonzalez, Noemí Puig, Maria Teresa Cedena Romero, Bruno Paiva, Adrian Alegre, Fernando Escalante Barrigón, Maria Belen Inigo-Rodriguez, Anabel Teruel, Luis Palomera, Aránzazu García-Mateo, Miguel Alvarez-Rivas, Enrique Ocio, Joan Batista Blade Creixenti, Juan-Jose Lahuerta Palacios, Jesus San-Miguel
Journal: Blood
Blood (2025) 146 (Supplement 1): 371.
https://doi.org/10.1182/blood-2025-371
Published: 2025
Journal Articles

Allogeneic hematopoietic cell transplantation in dyskeratosis congenita: Short and long- term outcome of 183 consecutive patients transplanted at EBMT centers

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Fabiana Cacace, Filomena Pierri, Francesca Fioredda, Laura Van Hussen-Daenen, Dirk-Jan Eikema, Joe Tuffnell, Brian Piepenbroek, Constantijn Halkes, Alexey Maschan, Flore Sicre-de-Fontbrune, Josu de la Fuente, Ali Al-Ahmari, Cristina Díaz-de-Heredia, Maura Faraci, Polina Stepensky, Mahmoud Aljurf, Persis Amrolia, Sarah Lawson, Elena Skorobogatova, R.F. Wynn, Benedicte Bruno, Jean-Hugues Dalle, Franca Fagioli, Tayfun Güngör, Marta Gonzalez Vicent, Franco Locatelli, Adam Nelson, Benedicte Neven, Victoria Potter, Adrian Alegre, Gerard Michel, Francesco Paolo Tambaro, Maria Ester Bernardo, Krzysztof Kalwak, Carlo Dufour, Austin Kulasekararaj, Antonio Risitano
Journal: Blood
Blood (2025) 146 (Supplement 1): 2490.
https://doi.org/10.1182/blood-2025-2490
Published: 2025
Journal Articles

Unraveling Long-Term Survival of Multiple Myeloma Patients, the GEM2000 Experience

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Rafael Alonso Fernandez, Andrés Arroyo Barea, Maria Teresa Cedena Romero, Laura Rosiñol Dachs, Javier de la Rubia, Sara Miqueleiz, Veronica Gonzalez-Calle, Felipe De Arriba, Luis Felipe Casado Montero, Miguel Teodoro Hernandez, Maria Mas Esteve, Pascual Fernandez, Paula Rodríguez-Otero, Carmen Calle Primo, Eugenia Abella, Paz Ribas, Adrian Alegre, Juan Miguel Bergua, Irene Gomez-Catalan, Jose Maria Arguiñano Perez, Luis Palomera, Enrique M Ocio, Maria Jose Busto Medina, Nieves Somolinos, Jose Maria Alonso Alonso, Aránzazu García Mateo, Joan Bargay, Pilar Delgado, Dunia De Miguel Llorente, Javier de la Cruz, Maria Victoria Mateos, Jesús F. San-Miguel, Joan Bladé, Juan-Jose Lahuerta Palacios, Joaquin Martinez Lopez
Journal: Blood
Blood (2024) 144 (Supplement 1): 1957.
https://doi.org/10.1182/blood-2024-211383
Published: 2024
Journal Articles

Covalent Menin Inhibitor Bmf-219 in Patients with Relapsed or Refractory (R/R) Acute Leukemia (AL): Preliminary Phase 1 Data from the Covalent-101 Study

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Jeffrey Lancet, Farhad Ravandi, Pau Montesinos, Jacqueline C. Barrientos, Talha Badar, Adrián Alegre, Asad Bashey, Juan Miguel Bergua Burgues, Lorenzo Brunetti, Emily K Curran, David C. Christian de Leeuw, Enrico Derenzini, Geert A. Huls, Jeroen J.W.M. Janssen, Deepa Jeyakumar, Mojca Jongen-Lavrencic, Ashwin Kishtagari, Maria-Victoria Mateos, Daniel Morillo, Alessandro Rambaldi, Aaron S. Rosenberg, Gary J. Schiller, Uzma Ahmed, Alexandru Cacovean, Stephan W. Morris, Courtney Follit, Brian Munneke, Ganesh Waghmare, Clarissa Mandap, Mona Vimal, Thomas Butler, Hetty E. Carraway
Journal: Blood
Blood (2023) 142 (Supplement 1): 2916.
https://doi.org/10.1182/blood-2023-173149
Published: 2023
Journal Articles

Isolated and Dynamic Peripheral Blood Residual Disease Status Characterized By Mass Spectrometry Predicts Outcome in Patients with High Risk Smoldering Multiple Myeloma Treated in the GEM-CESAR Trial

Free
Noemi Puig, Cristina Agullo, Teresa Contreras, Bruno Paiva, Maria Teresa Cedena Romero, José Juan Pérez, Irene Aires, Joaquin Martinez-Lopez, Paula Rodriguez Otero, Veronica Gonzalez-Calle, Marta Sonia Gonzalez Perez, Norma C. Gutierrez, Albert Oriol Rocafiguera, Rafael Ríos, Laura Rosiñol, Miguel Angel Alvarez Rivas, Maria Jose Calasanz, Bargay Joan, Ramon Garcia-Sanz, Ana Pilar Gonzalez, Adrián Alegre, Fernando Escalante, Rafael Martínez, Javier De La Rubia, Ana Isabel Teruel, Felipe De Arriba, Luis Palomera, Sergio Castro, Miguel Teodoro Hernández Garcia, Javier López, Aránzazu García Mateo, Enrique M Ocio, Joan Bladé, Juan Jose Lahuerta Palacios, Jesús San Miguel, Maria Victoria Mateos
Journal: Blood
Blood (2023) 142 (Supplement 1): 645.
https://doi.org/10.1182/blood-2023-182964
Published: 2023
Journal Articles

Belantamab Mafodotin in Patients with Relapsed/Refractory Multiple Myeloma Included in the Compassionate Use or the Expanded Access Program. Experience with a Spanish Cohort

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Javier De La Rubia, Rafael Alonso, Maria Esther Clavero Sanchez, Elham Askari, Alfonso García de Coca, Ana Maldonado, Margarita Fernandez De La Mata, Fernando Escalante, Ana Garcia-Feria, Rafael Rios, Venancio Conesa, Maria Aranzazu Bermudez, Beatriz Merchan, Alberto Velasco, María Jesús Blanchard, Antonia Sampol, Eukene Gainza González, Pedro M Hernandez, Veronica Gonzalez-Calle, Adrian Alegre
Journal: Blood
Blood (2022) 140 (Supplement 1): 4315–4317.
https://doi.org/10.1182/blood-2022-158538
Published: 2022
Journal Articles

COVID-19 Severity and Survival over Time in Vaccinated Patients with Hematologic Malignancies

Free
Joaquin Martinez Lopez, Javier De La Cruz, Rodrigo Gil-Manso, Celina Benavente Cuesta, Lauren Benito, jose Angel Hernandez, Maria Regina Herraez, Pilar Herrera Puente, Mi Kwon, Keina Quiroz, Andres Arroyo, Adrian Alegre, María Pilar Llamas Sillero, Javier López Jiménez, Pedro Sanchez-Godoy, Rafael F. Duarte, Jose L. Diez Martin, Víctor Jiménez-Yuste, Julio Garcia-Suarez
Journal: Blood
Blood (2022) 140 (Supplement 1): 7924–7925.
https://doi.org/10.1182/blood-2022-169545
Published: 2022
Journal Articles

Curative Strategy (GEM-CESAR) for High-Risk Smoldering Myeloma (SMM): Post-Hoc Analysis of Sustained Undetectable Measurable Residual Disease (MRD)

Free
Maria-Victoria Mateos, Joaquín Martínez-López, Paula Rodríguez-Otero, Jesús San-Miguel, Veronica Gonzalez-Calle, Marta Sonia Gonzalez, Albert Oriol, Norma C. Gutierrez, Rafael Rios, Laura Rosinol Dachs, Miguel Angel Alvarez, Joan Bargay, Ana Pilar Gonzalez, Fernando Escalante, Adrian Alegre, Belén Iñigo, Javier de la Rubia, Ana Isabel Teruel, Felipe De Arriba, Luis Palomera, Miguel-Teodoro Hernández, Javier Lopez Jimenez, Marta Reinoso Segura, Aránzazu García Mateo, Enrique M. Ocio, Joan Bladé, Juan-José Lahuerta, María Teresa Cedena, Noemi Puig, Bruno Paiva
Journal: Blood
Blood (2022) 140 (Supplement 1): 292–294.
https://doi.org/10.1182/blood-2022-159606
Published: 2022
Journal Articles

Elranatamab in Combination with Daratumumab for Patients (pts) with Relapsed/Refractory Multiple Myeloma (RRMM): Results from the Phase 3 Magnetismm-5 Study Safety Lead-in Cohort

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Sebastian Grosicki, Ulf-Henrik Mellqvist, Łukasz Pruchniewski, Jacob Crafoord, Suzanne Trudel, Chang-Ki Min, Darrell White, Adrian Alegre, Markus Hansson, Takashi Ikeda, Kazutaka Sunami, Eric Leip, Arthur Kudla, Gregory Finn, Youngil Koh
Journal: Blood
Blood (2022) 140 (Supplement 1): 4407–4408.
https://doi.org/10.1182/blood-2022-162738
Published: 2022
Journal Articles

Impact of the COVID-19 Pandemic on the Incidence Registry of Hematological Neoplasms in the Region of Madrid (Spain). Preliminary Report of 2014-2021

Free
Adrian Alegre, Luis Juarez-Salcedo, Víctor Jiménez-Yuste, Julio Garcia-Suarez, José Luis Díez-Martín, Joaquín Martínez-López, Beatriz Aguado, José Ángel Hernández-Rivas, Lauren Benito, Pilar Martinez-Barranco, Javier López Jiménez, Pedro Sanchez-Godoy, Fj Peñalver, Alberto Velasco, Adriana Pascual, Celina Benavente Cuesta, María Pilar Llamas Sillero, Juan Francisco DEL Campo, Elena Ruiz, Regina Herraez, Javier Ortiz, Carolina Miranda, Gregorio Garrido
Journal: Blood
Blood (2022) 140 (Supplement 1): 10965–10966.
https://doi.org/10.1182/blood-2022-167155
Published: 2022
Journal Articles

Immune Biomarkers of Survival and Severe Infection in Newly Diagnosed Multiple Myeloma (NDMM) Patients (pts) Treated with the Backbone Regimen Lenalidomide and Dexamethasone (Rd)

Free
Catarina Maia, Noemi Puig, Cristina Pérez Ruiz, Maria Teresa Cedena Romero, Camila Guerrero, Marta Larrayoz, Cirino Botta, Norma C. Gutierrez, María José Calasanz, Maria Luisa Martin-Ramos, Miguel Hernández, Laura Rosinol Dachs, Esther González Garcia, Felipe De Arriba, Albert Oriol, Veronica Gonzalez-Calle, Fernando Escalante, Javier de la Rubia, Mercedes Gironella Mesa, Rafael Rios, Ricarda Belen Garcia Sanchez, Jose Maria Arguiñano PEREZ, Adrian Alegre, Jesus Martin, María del Carmen Couto Caro, Maria Casanova, Mario Arnao Herraiz, Ernesto Pérez, Sebastián Garzón López, Marta Sonia Gonzalez Perez, Guillermo Martín-Nuñez, Adriana Rossi, Morton Coleman, Cristina Encinas, Ana M. Vale, Ana Isabel Teruel, María Cortés Rodríguez, Jose A. Martinez-Climent, Juan-José Lahuerta, Joan Bladé Creixenti, Ruben Niesvizky, Jesús San-Miguel, Maria-Victoria Mateos, Bruno Paiva
Journal: Blood
Blood (2022) 140 (Supplement 1): 4200–4203.
https://doi.org/10.1182/blood-2022-163058
Published: 2022
Journal Articles

Curative Strategy (GEM-CESAR) for High-Risk Smoldering Myeloma (SMM): Carfilzomib, Lenalidomide and Dexamethasone (KRd) As Induction Followed By HDT-ASCT, Consolidation with Krd and Maintenance with Rd

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Maria-Victoria Mateos, Joaquin Martinez Lopez, Paula Rodríguez-Otero, Veronica Gonzalez-Calle, Marta Sonia Gonzalez, Albert Oriol, Norma C. Gutierrez, Rafael Rios, Laura Rosinol, Miguel Angel Alvarez, Joan Bargay, Ana Pilar Gonzalez, Adrian Alegre, Fernando Escalante, Belén Iñigo, Javier de la Rubia, Ana Isabel Teruel, Felipe De Arriba, Luis Palomera, Miguel-Teodoro Hernández, Javier Lopez Jimenez, Aránzazu García Mateo, Marta Reinoso Segura, Enrique Ocio, Bruno Paiva, Noemi Puig, María Teresa Cedena, Joan Bladé, Juan Jose Lahuerta, Jesús F. San-Miguel
Journal: Blood
Blood (2021) 138 (Supplement 1): 1829.
https://doi.org/10.1182/blood-2021-148423
Published: 2021
Journal Articles

Compassionate Use of Belantamab Mafodotin for Treatment of Patients with Relapsed/Refractory Multiple Myeloma Heavily Treated. Spanish Experience

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Adrian Alegre, Gonzalo Benzo Callejo, Rafael Alonso Fernández, Joaquin Martínez-López, Ana Jimenez-Ubieto, Clara Cuellar, Elham Askari, Elena Prieto, Concha Alaez, Beatriz Aguado, Alberto Velasco, Isabel Krsnik, Laura Llorente, Cristina Muñoz-Linares, Ana Morales, Eugenio Gimenez Mesa, Rebeca Iglesias, Carmen Martínez-Chamorro, Arancha Alonso, Carmen Jiménez-Montes, María Jesús Blanchard
Journal: Blood
Blood (2021) 138 (Supplement 1): 3775.
https://doi.org/10.1182/blood-2021-151267
Published: 2021
Journal Articles

Acute and Post-Acute COVID-19 Severity and Mortality in Patients with Hematologic Malignancies: A Population-Based Registry Study

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Joaquin Martinez-Lopez, Javier De La Cruz, Rodrigo Gil-Manso, Angel Cedillo, Adrian Alegre, Maria Pilar Llamas Sillero, Rafael F. Duarte, Víctor Jiménez-Yuste, jose Angel Hernandez, Mi Kwon, Pedro Sanchez Godoy, Pilar Martinez-Barranco, Blanca Colás Lahuerta, Pilar Herrera Puente, Lauren Benito, Alberto Velasco, Arturo Matilla, Concha Alaez, Rafael Martos, Carmen Martínez-Chamorro, Keina Quiroz, Juan F del Campo, Adolfo De La Fuente, Maria Regina Herraez, Adriana Pascual, Elvira Gomez, Jaime Perez De Oteyza, Elena Ruiz, Jose Luis Diez Martin, Julio Garcia-Suarez
Journal: Blood
Blood (2021) 138 (Supplement 1): 186.
https://doi.org/10.1182/blood-2021-152539
Published: 2021
Journal Articles

Severity of Covid-19 Clinical Outcomes and Mortality in Multiple Myeloma Patients over Year 1 of the Pandemic

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Joaquín Martínez-López, Maria-Victoria Mateos, Nieves López-Muñoz, Maria Alicia Senin Magan, Maria Dunia De Miguel, Ana López de la Guía, Anna Sureda, Cristina Encinas, Diego Conde Royo, Laura Rosinol, Lucía García Tomás, Jose Angel Hernandez-Rivas, Javier Alberto Rojas, Adrian Alegre, María Jesús Blanchard, Fernando Escalante Barrigón, Esther González Garcia, Belén Iñigo, Pilar Bravo Barahona, F. Javier Penalver, Javier De La Rubia, Noemi Fernandez-Escalada, Jose Maria Alonso Alonso, Joan Bladé, Juan Jose Lahuerta, Javier De La Cruz, Jesús F. San-Miguel
Journal: Blood
Blood (2021) 138 (Supplement 1): 2719.
https://doi.org/10.1182/blood-2021-149192
Published: 2021
Journal Articles

HORIZON (OP-106): Melflufen Plus Dexamethasone (dex) in Patients (pts) with Relapsed/Refractory Multiple Myeloma (RRMM) Exposed to Prior Alkylator Therapy-Subgroup Analysis

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Paula Rodríguez-Otero, MD PhD, María-Victoria Mateos, MD PhD, Albert Oriol, Alessandra Larocca, Joan Blade Creixenti, Michele Cavo, Xavier Leleu, MD, Maxim Norkin, MD PhD, Omar Nadeem, MD, John W. Hiemenz, MD, Hani Hassoun, MD, Cyrille Touzeau, Adrián Alegre Amor, MD PhD, Agne Paner, MD, Christopher Maisel, MD, Amitabha Mazumder, MD, Anastasios Raptis, MD, Noemí Puig, MD PhD, Marcus Thuresson, PhD, Johan Harmenberg, MD PhD, Olof Harlin, VMD, PhD, Paul G. Richardson, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 22–23.
https://doi.org/10.1182/blood-2020-136466
Published: 2020
Journal Articles

HORIZON (OP-106): Melflufen Plus Dexamethasone in Patients with Relapsed/Refractory Multiple Myeloma-Age Subgroup Analysis of Elderly Patients

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Alessandra Larocca, Paul G. Richardson, MD, Albert Oriol, Joan Blade Creixenti, Michele Cavo, Paula Rodríguez-Otero, MD PhD, Xavier Leleu, MD, Maxim Norkin, MD PhD, Omar Nadeem, MD, John W. Hiemenz, MD, Hani Hassoun, MD, Cyrille Touzeau, Adrián Alegre Amor, MD PhD, Agne Paner, MD, Christopher Maisel, MD, Amitabha Mazumder, MD, Anastasios Raptis, MD, Noemí Puig, MD PhD, Marcus Thuresson, PhD, Johan Harmenberg, MD PhD, Bengt Gustavsson, Dr MDSci, MSc Pharm, María-Victoria Mateos, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 44–46.
https://doi.org/10.1182/blood-2020-136856
Published: 2020